Drug & supplement interaction

Wood Sorrel + Enasidenib

Enasidenib brand name: Idhifa.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Wood Sorrel and Enasidenib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Wood Sorrel and Enasidenib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Enasidenib and Wood Sorrel in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Wood Sorrel at all — not against Enasidenib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Wood Sorrel safety at a glance

Wood Sorrel overall Use caution Generally used as a food in small amounts, but its oxalic acid content makes large or frequent use risky.
Pregnancy Avoid Not enough safety information; best avoided in medicinal amounts during pregnancy.
Breastfeeding Possibly Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Enasidenib and Wood Sorrel? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Wood Sorrel and Enasidenib May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Diarrhea / Nausea Additional detail

    Wood Sorrel

    “Orally, consuming excessive amounts of wood sorrel can cause diarrhea, nausea, and other gastrointestinal symptoms. Wood sorrel contains oxalic acid, which is thought to be responsible for these adverse effects (6,17).”

    Wood Sorrel · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
    2. 17. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.

    Enasidenib

    Listed in the ADVERSE REACTIONS section of the FDA label for Enasidenib. Read the label on DailyMed ›

  • A skin rash Additional detail

    Wood Sorrel

    “Orally, consuming excessive amounts of wood sorrel can cause dermatitis. Wood sorrel contains oxalic acid, which is thought to be responsible for this adverse effect (4,17).”

    Wood Sorrel · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 17. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.

    Enasidenib

    Listed in the ADVERSE REACTIONS section of the FDA label for Enasidenib. Read the label on DailyMed ›

Reported for Wood Sorrel but not commonly for Enasidenib: passing urine more often.

Effects for Enasidenib come from the ADVERSE REACTIONS section of its FDA label; effects for Wood Sorrel come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Wood Sorrel in Pregnancy & Breastfeeding

Lactation Possibly Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Enasidenib

This page covers Wood Sorrel only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Enasidenib page lists 203 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), 1,3-dmaa (moderate) and Acacia Rigidula (moderate).

By severity: 3 major · 156 moderate · 44 minor.

From our pharmacist’s overview on the Enasidenib page

“Anyone taking enasidenib (Idhifa) for acute myeloid leukemia should treat this supplement list with genuine care, beginning with the major-rated entries: grapefruit, St. John's wort, and activated charcoal.”

Reviewed by 2 · Jul 18, 2026

Open the Enasidenib interaction page

How much people look this up

Where Wood Sorrel and Enasidenib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Wood Sorrel
Steady interest

#1,424 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Enasidenib
Steady interest

#2,414 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Wood Sorrel reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Wood Sorrel and Enasidenib records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Wood Sorrel

What is Wood Sorrel?

  • Digestive upset
  • Mouth and throat soothing
  • Mild diuretic
  • Fever and thirst relief
  • Wound and skin care (traditional)

Wood sorrel is a small, sour-tasting wild plant used in folk medicine and as a tangy edible green. There is very little modern research to support any health use, and its naturally high oxalic acid content means it should be used in small amounts. People with kidney problems, gout, or who are pregnant should be especially cautious.

Oxalis acetosella · Oxalidaceae · Leaves and aerial parts · Fresh leaves, tea, tincture, juice

An interaction check asks whether these two react with each other — it does not ask whether Wood Sorrel is a good idea for someone in your situation. Here is what our Wood Sorrel record says about it on its own.

Wood Sorrel: dosing

There is no established or standardized medicinal dose for wood sorrel. It has been used traditionally as fresh leaves, a tea, or a juice, but no reliable guidelines exist for how much is safe or effective.Because of its oxalic acid content, it is wise to keep any use to small amounts and avoid taking it regularly.

From our Wood Sorrel monograph — the full record covers uses, side effects and every documented interaction.

Read the full Wood Sorrel monograph & all interactions
Medication

About Enasidenib

What Is Enasidenib Used For?

Brand name: Idhifa

Idhifa (enasidenib) is used to treat adult patients with acute myeloid leukemia (AML) — a fast-moving cancer of the blood and bone marrow — whose disease has come back after treatment (relapsed) or has stopped responding to treatment (refractory). It is specifically for patients whose leukemia has a mutation in the IDH2 gene, which must be confirmed by an FDA-approved test before starting therapy.

See full Enasidenib drug information
Keep checking

Other Drugs & Wood Sorrel

Browse every other medication we’ve checked against Wood Sorrel — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Wood Sorrel against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Wood Sorrel list.

See the full Wood Sorrel interactions page
See every supplement checked against Enasidenib, ranked by severity
Evidence & sources

Wood Sorrel References

The 3 references that drive our Wood Sorrel monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Wood Sorrel and Enasidenib Together: Common Questions

Is it safe to take Wood Sorrel with Enasidenib?
We do not list a known interaction between Wood Sorrel and Enasidenib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Wood Sorrel and Enasidenib have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Enasidenib interact with any supplements?
Yes. Enasidenib has documented interactions with 203 supplements in our database — Wood Sorrel is not one of them. The Enasidenib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Wood Sorrel monograph Uses, safety profile, and every drug interaction in one place Enasidenib drug information The full plain-English guide to this medication Enasidenib supplement interactions Every supplement checked against Enasidenib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Enasidenib and Wood Sorrel?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.