Drug & supplement interaction

Wood Sorrel + Tadalafil

Tadalafil brand names: Cialis, Tadliq.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Wood Sorrel and Tadalafil in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Wood Sorrel and Tadalafil

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tadalafil and Wood Sorrel in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Wood Sorrel at all — not against Tadalafil, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Wood Sorrel safety at a glance

Wood Sorrel overall Use caution Generally used as a food in small amounts, but its oxalic acid content makes large or frequent use risky.
Pregnancy Avoid Not enough safety information; best avoided in medicinal amounts during pregnancy.
Breastfeeding Possibly Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tadalafil and Wood Sorrel? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Wood Sorrel Itself Has Been Linked To

This is not an interaction — nothing below involves Tadalafil. It is the side-effect record for Wood Sorrel on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Wood Sorrel, this list is the first place to look.

  • Passing urine more often Additional detail

    “There is currently a limited amount of information on the adverse effects of wood sorrel. A thorough evaluation of safety outcomes has not been conducted.

    Most Common Adverse Effects:

    Orally: Dermatitis, diarrhea, nausea, and polyuria.”

    Wood Sorrel · Natural Medicines adverse-effect record, reported in dermatitis.

  • Diarrhea / Nausea Additional detail

    “Orally, consuming excessive amounts of wood sorrel can cause diarrhea, nausea, and other gastrointestinal symptoms. Wood sorrel contains oxalic acid, which is thought to be responsible for these adverse effects (6,17).”

    Wood Sorrel · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
    2. 17. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  • A skin rash Additional detail

    “Orally, consuming excessive amounts of wood sorrel can cause dermatitis. Wood sorrel contains oxalic acid, which is thought to be responsible for this adverse effect (4,17).”

    Wood Sorrel · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 17. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.

Everything above comes from the Natural Medicines adverse-effect record for Wood Sorrel — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Tadalafil’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Tadalafil column appears here.

Special populations

Wood Sorrel in Pregnancy & Breastfeeding

Lactation Possibly Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Wood Sorrel or Tadalafil

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Wood Sorrel or Tadalafil, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Tadalafil

This page covers Wood Sorrel only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tadalafil page lists 144 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Mistletoe (major), Grapefruit (major), Hawthorn (major) and St. John's Wort (major).

By severity: 5 major · 98 moderate · 41 minor.

From our pharmacist’s overview on the Tadalafil page

“Grapefruit juice is the first thing to know about if you take tadalafil (Cialis, Tadliq). It blocks CYP3A4, the enzyme that clears the drug, so blood levels climb and side effects like a steep drop in blood pressure become more likely.”

Reviewed by 2 · Jul 18, 2026

Open the Tadalafil interaction page

How much people look this up

Where Wood Sorrel and Tadalafil Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Wood Sorrel
Steady interest

#1,424 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tadalafil
Top 1%

#20 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Wood Sorrel reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Wood Sorrel and Tadalafil records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Wood Sorrel

What is Wood Sorrel?

  • Digestive upset
  • Mouth and throat soothing
  • Mild diuretic
  • Fever and thirst relief
  • Wound and skin care (traditional)

Wood sorrel is a small, sour-tasting wild plant used in folk medicine and as a tangy edible green. There is very little modern research to support any health use, and its naturally high oxalic acid content means it should be used in small amounts. People with kidney problems, gout, or who are pregnant should be especially cautious.

Oxalis acetosella · Oxalidaceae · Leaves and aerial parts · Fresh leaves, tea, tincture, juice

An interaction check asks whether these two react with each other — it does not ask whether Wood Sorrel is a good idea for someone in your situation. Here is what our Wood Sorrel record says about it on its own.

Wood Sorrel: dosing

There is no established or standardized medicinal dose for wood sorrel. It has been used traditionally as fresh leaves, a tea, or a juice, but no reliable guidelines exist for how much is safe or effective.Because of its oxalic acid content, it is wise to keep any use to small amounts and avoid taking it regularly.

From our Wood Sorrel monograph — the full record covers uses, side effects and every documented interaction.

Read the full Wood Sorrel monograph & all interactions
Medication

About Tadalafil

What Is Tadalafil Used For?

Brand names: Cialis, Tadliq

Tadalafil tablets (including Cialis and generic tadalafil) are used to treat erectile dysfunction (ED), the symptoms of benign prostatic hyperplasia (BPH — an enlarged prostate), or both conditions together. When used with the drug finasteride to start BPH treatment, this combination is recommended for up to 26 weeks.

Adcirca, Alyq (tablets), and Tadliq (oral suspension) are indicated specifically for pulmonary arterial hypertension (PAH — high blood pressure in the lungs), to improve the ability to exercise.

Most-Reported Side Effects for Tadalafil

From FAERS, the FDA’s public side-effect reporting system (99,210 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 11,917 reports
Headache 10,982 reports
Diarrhea 8,020 reports
Nausea 6,697 reports
Fatigue 6,080 reports
See full Tadalafil drug information
Keep checking

Other Drugs & Wood Sorrel

Browse every other medication we’ve checked against Wood Sorrel — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Wood Sorrel against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Wood Sorrel list.

See the full Wood Sorrel interactions page
See every supplement checked against Tadalafil, ranked by severity
Evidence & sources

Wood Sorrel References

The 3 references that drive our Wood Sorrel monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Wood Sorrel and Tadalafil Together: Common Questions

Is it safe to take Wood Sorrel with Tadalafil?
We do not list a known interaction between Wood Sorrel and Tadalafil. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Tadalafil interact with any supplements?
Yes. Tadalafil has documented interactions with 144 supplements in our database — Wood Sorrel is not one of them. The Tadalafil interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Wood Sorrel monograph Uses, safety profile, and every drug interaction in one place Tadalafil drug information The full plain-English guide to this medication Tadalafil supplement interactions Every supplement checked against Tadalafil, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Tadalafil and Wood Sorrel?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.