Yarrow + Hydrochlorothiazide, Lisinopril
Hydrochlorothiazide, Lisinopril brand names: Zestoretic, Prinzide.
We found no known interaction between Yarrow and Hydrochlorothiazide, Lisinopril in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Yarrow and Hydrochlorothiazide, Lisinopril
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Hydrochlorothiazide, Lisinopril and Yarrow in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Yarrow safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Hydrochlorothiazide, Lisinopril
Interactions in our licensed database are recorded against drug classes, not just single drug names. Hydrochlorothiazide, Lisinopril is filed under 10 classifications — including lisinopril, ace inhibitors (aceis), thiazide diuretics. Yarrow has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Hydrochlorothiazide, Lisinopril’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Yarrow Does Interact With Other Medications
Yarrow has 1 moderate known drug interaction in our database — Hydrochlorothiazide, Lisinopril isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Yarrow
We haven’t checked that one against Yarrow yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Yarrow. Pick one to open its full report.
Yarrow in Pregnancy & Breastfeeding
When used orally; yarrow is believed to be an abortifacient and affect the menstrual cycle.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Hydrochlorothiazide, Lisinopril
This page covers Yarrow only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Hydrochlorothiazide, Lisinopril page lists 236 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Dolomite (major).
By severity: 10 major · 199 moderate · 27 minor.
From our pharmacist’s overview on the Hydrochlorothiazide, Lisinopril page
“I would not add a supplement casually alongside hydrochlorothiazide and lisinopril (Zestoretic, Prinzide). This combination lowers blood pressure with a water pill plus an ACE inhibitor, and most interacting ingredients either drag pressure down too far or push back against the drug, while smaller groups strain the kidneys, drain potas…”
Reviewed by 2 · Jul 18, 2026
Taking Yarrow as Part of a Dietary Supplement Product? Check It for Interactions
We hold 600 real supplement products containing Yarrow, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Yarrow. Even though Yarrow itself has no known interaction with Hydrochlorothiazide, Lisinopril, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Yarrow and Hydrochlorothiazide, Lisinopril Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#336 of 1,452 supplements looked up here in the last 7 days
#633 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Yarrow reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Yarrow and Hydrochlorothiazide, Lisinopril records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Yarrow
What is Yarrow?
- Wounds and minor bleeding
- Digestive upset and cramping
- Colds, flu, and fever
- Skin conditions
- Menstrual discomfort
Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used short-term, and people who are pregnant, breastfeeding, or allergic to ragweed and related plants should avoid it.
Achillea millefolium · Asteraceae · Aerial parts (leaves, flowers, and stems) and essential oil · Tea, tincture, capsules, dried herb, topical creams or ointments, and essential oil
An interaction check asks whether these two react with each other — it does not ask whether Yarrow is a good idea for someone in your situation. Here is what our Yarrow record says about it on its own.
Yarrow: dosing
There is no official, standardized dose for yarrow. Traditional use includes teas made from the dried herb, tinctures, and capsules, as well as creams applied to the skin.Because product strengths vary widely, the safest approach is to follow the directions on the product label and not exceed them. Yarrow is intended for short-term use, not long-term daily use.
From our Yarrow monograph — the full record covers uses, side effects and every documented interaction.
About Lisinopril and Hydrochlorothiazide
What Is Lisinopril and Hydrochlorothiazide Used For?
Brand names: Zestoretic, Prinzide
Lisinopril and hydrochlorothiazide tablets — sold as the brand Zestoretic and as the generic combination — are used to treat high blood pressure (hypertension). Lowering blood pressure reduces the risk of serious cardiovascular events such as stroke and heart attack.
This is a fixed-dose combination product and is not intended as a first-line (initial) treatment for high blood pressure. It is typically prescribed for patients whose blood pressure is not adequately controlled on a single medication alone.
Other Drugs & Yarrow
Browse every other medication we’ve checked against Yarrow — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
1 interaction
No interaction 2,828 drugs checked — show the list
We also checked Yarrow against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Acetaminophen ›
- Tadalafil ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Abemaciclib ›
- Hydroxyurea ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Warfarin Sodium ›
- Tirzepatide ›
- Prednisone ›
- Propranolol ›
- Bupropion ›
- Metformin ›
- Lisdexamfetamine ›
- Amoxicillin ›
- Lisinopril ›
- Acyclovir ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Methotrexate ›
- Lamotrigine ›
- Fluoxetine ›
- Amphetamine ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Pregabalin ›
- Azithromycin ›
- Dextroamphetamine ›
- Isotretinoin ›
- Clonazepam ›
- Omeprazole ›
- Methylene Blue ›
- Quetiapine ›
- Amlodipine Besylate ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Naproxen ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Yarrow list.
Yarrow References
The 8 references that drive our Yarrow monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
- Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
- Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
- Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
- Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
- de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
- Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Hydrochlorothiazide, Lisinopril Is Linked to Lower Levels of 8 Nutrients
Natural Medicines records Hydrochlorothiazide, Lisinopril as a medicine that can lower these. This is not an interaction with Yarrow — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Hydrochlorothiazide, Lisinopril nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Yarrow and Hydrochlorothiazide, Lisinopril Together: Common Questions
Is it safe to take Yarrow with Hydrochlorothiazide, Lisinopril?
Do Yarrow and Hydrochlorothiazide, Lisinopril have any of the same side effects?
How was the Yarrow and Hydrochlorothiazide, Lisinopril combination checked?
Does Yarrow interact with any other medications?
Does Hydrochlorothiazide, Lisinopril interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.