Drug & supplement interaction

Yarrow + Mupirocin

Mupirocin brand name: Bactroban.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Yarrow and Mupirocin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Yarrow and Mupirocin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mupirocin and Yarrow in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Yarrow safety at a glance

Yarrow overall Use caution Often used short-term, but human safety data are limited and allergic reactions can occur.
Pregnancy Likely Unsafe When used orally; yarrow is believed to be an abortifacient and affect the menstrual cycle. Read the full pregnancy detail
Breastfeeding Avoid Not enough safety information, so it is best avoided while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mupirocin and Yarrow? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Mupirocin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Mupirocin is filed under a single classification — topical drugs. Yarrow has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Mupirocin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Yarrow Does Interact With Other Medications

Yarrow has 1 moderate known drug interaction in our database — Mupirocin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 1 No known interaction 2,829 (incl. Mupirocin)
Taking anything else?

Check Another of Your Medications Against Yarrow

Covers the 2,830 medications we’ve checked against Yarrow. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Yarrow and Mupirocin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Hives Worth acting on Additional detail

    Yarrow

    “Topically, yarrow can cause atopic or allergic dermatitis or urticaria due to its sesquiterpene lactone content. Yarrow has also been reported to cause phototoxic and photo-allergic dermatitis and airborne contact dermatitis.

    Intravaginally, aggravated facial acne was reported by 1 of 40 patients in a clinical trial.”

    Yarrow · Natural Medicines adverse-effect record, reported in acne.

    4 sources cited
    1. 52558. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
    2. 68385. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
    3. 77007. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
    4. 105360. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed

    “Topically, yarrow can cause atopic or allergic dermatitis or urticaria due to its sesquiterpene lactone content. It has also been reported to cause phototoxic and photo-allergic dermatitis and airborne contact dermatitis. In one 44-year-old female, handling yarrow flowers resulted in rhinitis and asthma.”

    Yarrow · Natural Medicines adverse-effect record, reported in asthma.

    4 sources cited
    1. 52558. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
    2. 68385. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
    3. 77007. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
    4. 96911. Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.

    Mupirocin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mupirocin. Read the label on DailyMed ›

  • Itching Additional detail

    Yarrow

    “Intravaginally, aggravated vaginal pruritus and dryness were reported by 1 of 40 patients in a clinical trial.”

    Yarrow · Natural Medicines adverse-effect record, reported in pruritus.

    1 source cited
    1. 105360. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed

    Mupirocin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mupirocin. Read the label on DailyMed ›

  • A skin rash reported in 4.5% of FDA reports for Mupirocin Additional detail

    Yarrow

    “Orally and intravaginally, yarrow seems to be well tolerated.

    Most Common Adverse Effects:

    Topically: Dermatitis.”

    Yarrow · Natural Medicines adverse-effect record, reported in dermatitis.

    Mupirocin

    Listed in the ADVERSE REACTIONS section of the FDA label for Mupirocin, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Reported for Yarrow but not commonly for Mupirocin: a stuffy or runny nose, wheezing and acne.

Effects for Mupirocin come from the ADVERSE REACTIONS section of its FDA label; effects for Yarrow come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 13,756 voluntary FDA FAERS reports for Mupirocin that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Yarrow in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally; yarrow is believed to be an abortifacient and affect the menstrual cycle.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Yarrow or Mupirocin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Yarrow or Mupirocin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Mupirocin

This page covers Yarrow only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mupirocin page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Mupirocin page

“Rubbing DMSO onto skin that is also being treated with mupirocin (Bactroban), a prescription antibiotic ointment for skin infections such as impetigo, could push more of the drug through the skin than intended, raising both its effects and its side effects. That is the biggest concern on a short list.”

Reviewed by 2 · Jul 18, 2026

Open the Mupirocin interaction page

One more smart check

Taking Yarrow as Part of a Dietary Supplement Product? Check It for Interactions

We hold 600 real supplement products containing Yarrow, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Yarrow. Even though Yarrow itself has no known interaction with Mupirocin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Yarrow and Mupirocin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Yarrow
Top 25%

#273 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mupirocin
Steady interest

#2,252 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Yarrow reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Yarrow and Mupirocin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Yarrow

What is Yarrow?

Yarrow
  • Wounds and minor bleeding
  • Digestive upset and cramping
  • Colds, flu, and fever
  • Skin conditions
  • Menstrual discomfort

Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used short-term, and people who are pregnant, breastfeeding, or allergic to ragweed and related plants should avoid it.

Achillea millefolium · Asteraceae · Aerial parts (leaves, flowers, and stems) and essential oil · Tea, tincture, capsules, dried herb, topical creams or ointments, and essential oil

An interaction check asks whether these two react with each other — it does not ask whether Yarrow is a good idea for someone in your situation. Here is what our Yarrow record says about it on its own.

Yarrow: dosing

There is no official, standardized dose for yarrow. Traditional use includes teas made from the dried herb, tinctures, and capsules, as well as creams applied to the skin.Because product strengths vary widely, the safest approach is to follow the directions on the product label and not exceed them. Yarrow is intended for short-term use, not long-term daily use.

From our Yarrow monograph — the full record covers uses, side effects and every documented interaction.

Read the full Yarrow monograph & all interactions
Medication

About Mupirocin

What Is Mupirocin Used For?

Brand name: Bactroban

Mupirocin ointment is approved to treat impetigo — a common contagious skin infection — caused by susceptible strains of Staphylococcus aureus or Streptococcus pyogenes.

Mupirocin cream (including the brand Pirnuo) is approved for secondarily infected traumatic skin lesions — meaning minor cuts, scrapes, or wounds that have become infected — up to a certain size, caused by those same bacteria.

Most-Reported Side Effects for Mupirocin

From FAERS, the FDA’s public side-effect reporting system (13,756 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 955 reports
Fatigue 821 reports
Macular degeneration 820 reports
Headache 765 reports
Diarrhea 705 reports
See full Mupirocin drug information
Keep checking

Other Drugs & Yarrow

Browse every other medication we’ve checked against Yarrow — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
1Moderate
0Minor
2,828No known interaction
1 Moderate 2,828 No interaction
Moderate

1 interaction

No interaction 2,828 drugs checked — show the list

We also checked Yarrow against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Yarrow list.

See the full Yarrow interactions page
See every supplement checked against Mupirocin, ranked by severity
Evidence & sources

Yarrow References

The 8 references that drive our Yarrow monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
  3. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
  4. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
  5. Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
  6. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
  7. de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
  8. Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Yarrow and Mupirocin Together: Common Questions

Is it safe to take Yarrow with Mupirocin?
We do not list a known interaction between Yarrow and Mupirocin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Yarrow and Mupirocin have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Yarrow and Mupirocin combination checked?
Interactions in our licensed database are recorded against drug classes. Mupirocin is filed under 1 classification, and Yarrow has documented interactions with 1 drug class — none of Mupirocin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Yarrow interact with any other medications?
Yes. Yarrow has 1 documented drug interaction in our database — Mupirocin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Mupirocin interact with any supplements?
Yes. Mupirocin has documented interactions with 3 supplements in our database — Yarrow is not one of them. The Mupirocin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Yarrow monograph Uses, safety profile, and every drug interaction in one place Mupirocin drug information The full plain-English guide to this medication Mupirocin supplement interactions Every supplement checked against Mupirocin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 8 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Mupirocin and Yarrow?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.