Drug & supplement interaction

Yoga + Propoxyphene

Propoxyphene brand names: Darvon, Prophene-65, Margesic, Davon.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Yoga and Propoxyphene in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Yoga and Propoxyphene

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Propoxyphene and Yoga in our sources. This does not guarantee that the combination is completely free of risk — research on Yoga alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Yoga at all — not against Propoxyphene, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Yoga is a practice rather than something you take. Ask your care team whether the type and intensity you plan to practice are appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Yoga safety at a glance

Yoga overall Generally safe Generally safe for most people when practiced appropriately and within personal limits.
Pregnancy Possibly Safe When used appropriately. Some clinical research shows that yoga during pregnancy does not adversely affect birth outcomes. However, some aggressive forms of yog... Read the full pregnancy detail
Breastfeeding Possibly Safe When used appropriately. Some clinical research shows that yoga during pregnancy does not adversely affect birth outcomes. However, some aggressive forms of yog... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Propoxyphene and Yoga? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Yoga and Propoxyphene May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so practicing Yoga while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Low mood Worth acting on Additional detail

    Yoga

    “Chronic headache, sleep problems, cerebral hemorrhage, tingling, vertigo, and depressive symptoms have all been reported rarely by individuals practicing yoga. A case of acute cervical myelopathy with concurrent cervical arterial dissection is reported in a 63-year-old after performing the Vrischikasana yoga pose. The patient was hospitalized and recovered gradually following surgery and antithrombotic treatment.”

    Yoga · Natural Medicines adverse-effect record, reported in cluster headache.

    3 sources cited
    1. 101533. Cramer H, Quinker D, Schumann D, Wardle J, Dobos G, Lauche R. Adverse effects of yoga: a national cross-sectional survey. BMC Complement Altern Med. 2019 Jul 29;19(1):190. doi: 10.1186/s12906-019-2612-7. PubMed
    2. 105351. Simon NM, Hofmann SG, Rosenfield D, et al. Efficacy of yoga vs cognitive behavioral therapy vs stress education for the treatment of generalized anxiety disorder: A randomized clinical trial. JAMA Psychiatry. 2021;78(1):13-20. PubMed
    3. 111578. Nayar G, Desai A, Agarwal N, Alan N, Moossy JJ. Cervical arterial dissection and traumatic myelopathy following yoga: surgical case report. Spinal Cord Ser Cases 2022;8(1):46. PubMed

    Propoxyphene

    Listed in the ADVERSE REACTIONS section of the FDA label for Propoxyphene. Read the label on DailyMed ›

  • Numbness or tingling / Dizziness Additional detail

    Yoga

    Recorded for Yoga in the same Natural Medicines adverse-effect record shown under Low mood above.

    Propoxyphene

    Listed in the ADVERSE REACTIONS section of the FDA label for Propoxyphene. Read the label on DailyMed ›

  • Headache Additional detail

    Yoga

    “Yoga is generally safe and well tolerated.

    Most Common Adverse Effects:

    Temporary musculoskeletal pain.

    Serious Adverse Effects (Rare):

    Cerebral hemorrhage, chronic back, neck, shoulder, knee, or hip pain, chronic headache, fractures, sciatica, strains and sprains, and tendon shortening. Hot yoga has been reported to cause heat stroke.”

    Yoga · Natural Medicines adverse-effect record, reported in chronic obstructive pulmonary disease (copd).

    Propoxyphene

    Listed in the ADVERSE REACTIONS section of the FDA label for Propoxyphene. Read the label on DailyMed ›

Reported for Yoga but not commonly for Propoxyphene: muscle pain and bleeding or bruising.

Effects for Propoxyphene come from the ADVERSE REACTIONS section of its FDA label; effects for Yoga come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Yoga in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Safe

When used appropriately. Some clinical research shows that yoga during pregnancy does not adversely affect birth outcomes. However, some aggressive forms of yoga exercises might not be safe to use during pregnancy.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Propoxyphene Is Prescribed For, and What Yoga Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Propoxyphene is a prescription medicine with approved uses on its FDA label. Yoga is a practice: what follows is what researchers have looked at it for, and how strong that evidence is.

Propoxyphene is prescribed for: This three-ingredient combination — butalbital, acetaminophen, and caffeine — is used to relieve the symptoms of tension headache (also called muscle contraction headache). All supported products, including tablets, capsules, and oral solution, share this same approved use. It is worth knowing that evidence for using this combination to treat repeated, frequent tension headaches over time is limited. Because butalbital can be habit-forming, extended or repeated use is not recommended.

Yoga has been studied for:

  • Tension headache studied, not established Yoga has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Yoga for tension headache

    It is unclear if yoga is beneficial in patients with tension headache.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Propoxyphene on your own; if you are taking Yoga for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Propoxyphene

This page covers Yoga only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Propoxyphene page lists 172 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 8 major · 141 moderate · 23 minor.

From our pharmacist’s overview on the Propoxyphene page

“Propoxyphene (Darvon) is an opioid painkiller, and the biggest hazard among the 172 supplement interactions on file is anything else that slows the brain and breathing. Seventy-eight of these ingredients pile on that sedation, alcohol and kava among the worst rated, and with an opioid the combination can push breathing dangerously low.”

Reviewed by 2 · Jul 18, 2026

Open the Propoxyphene interaction page

How much people look this up

Where Yoga and Propoxyphene Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Yoga
Steady interest

#1,265 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Propoxyphene
Top 5%

#84 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Yoga reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Yoga and Propoxyphene records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Mind-body practice

About Yoga

What is Yoga?

  • Stress and anxiety
  • Low back pain
  • Flexibility and balance
  • Sleep problems
  • Depression and mood
  • General wellness and fitness

Yoga is a mind-body practice combining physical postures, breathing techniques, and meditation, not a dietary supplement or herb. Research suggests it may help with stress, back pain, mood, and overall well-being, and it is generally safe for most people when practiced carefully. Beginners and those with health conditions should start gently and talk to a doctor before beginning.

Not applicable (mind-body practice) · Hatha yoga, Vinyasa, Iyengar, restorative yoga, breathing exercises (pranayama), meditation classes, online videos, group or private sessions

An interaction check asks whether these two react with each other — it does not ask whether Yoga is a good idea for someone in your situation. Here is what our Yoga record says about it on its own.

Yoga: dosing

There is no standard "dose" for yoga the way there is for a supplement. Benefits often come from regular, ongoing practice rather than a single session.Many studies use sessions lasting from about 30 to 90 minutes, practiced once or several times per week. A good approach is to start with shorter, gentler sessions and gradually build up as your comfort and ability improve.If you are new to yoga or have a health condition, consider working with a qualified instructor and checking with your doctor or pharmacist to make sure your chosen style is appropriate for you.

From our Yoga monograph — the full record covers uses, side effects and every documented interaction.

Read the full Yoga monograph & all interactions
Medication

About Acetaminophen, Butalbital, and Caffeine

What Is Acetaminophen, Butalbital, and Caffeine Used For?

Brand names: Darvon, Prophene-65, Margesic, Davon

This three-ingredient combination — butalbital, acetaminophen, and caffeine — is used to relieve the symptoms of tension headache (also called muscle contraction headache). All supported products, including tablets, capsules, and oral solution, share this same approved use.

It is worth knowing that evidence for using this combination to treat repeated, frequent tension headaches over time is limited. Because butalbital can be habit-forming, extended or repeated use is not recommended.

See full Acetaminophen, Butalbital, and Caffeine drug information
Keep checking

Other Drugs & Yoga

Browse every other medication we’ve checked against Yoga — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Yoga against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Yoga list.

See the full Yoga interactions page
See every supplement checked against Propoxyphene, ranked by severity
Evidence & sources

Yoga References

The 19 references that drive our Yoga monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Chuntharapat S, Petpichetchian W, Hatthakit U. Yoga during pregnancy: effects on maternal comfort, labor pain and birth outcomes. Complement Ther Clin Pract 2008;14:105-15. PubMed
  2. Narendran S, Nagarathna R, Narendran V, et al. Efficacy of yoga on pregnancy outcome. J Altern Complement Med 2005;11:237-44. PubMed
  3. Kashyap AS, Anand KP, Kashyap S. Complications of yoga. Emerg Med J 2007;24:231. PubMed
  4. Johnson DB, Tierney MJ, Sadighi PJ. Kapalabhati pranayama: breath of fire or cause of pneumothorax? A case report. Chest 2004;125:1951-2. PubMed
  5. Boddu P, Patel S, Shahrrava A. Sudden Cardiac Arrest From Heat Stroke: Hidden Dangers of Hot Yoga. Am J Med. 2016;129(8):e129-30.
  6. Campo M, Shiyko MP, Kean MB, Roberts L, Pappas E. Musculoskeletal pain associated with recreational yoga participation: A prospective cohort study with 1-year follow-up, Journal of Bodywork & Movement Therapies (2017). PubMed
  7. Wieland LS, Skoetz N, Pilkington K, Vempati R, D'Adamo CR, Berman BM. Yoga treatment for chronic non-specific low back pain. Cochrane Database Syst Rev. 2017;1:CD010671. DOI
  8. Schmid AA, Fruhauf CA, Sharp JL, Van Puymbroeck MV, Bair MJ, Portz JD. Yoga for People With Chronic Pain in a Community-Based Setting: A Feasibility and Pilot RCT. J Evid Based Integr Med. 2019 Jan-Dec;24:2515690X19863763. doi: 10.1177/2515690X19863763. PubMed
  9. Cramer H, Quinker D, Schumann D, Wardle J, Dobos G, Lauche R. Adverse effects of yoga: a national cross-sectional survey. BMC Complement Altern Med. 2019 Jul 29;19(1):190. doi: 10.1186/s12906-019-2612-7. PubMed
  10. Wiese C, Keil D, Rasmussen AS, Olesen R. Injury in yoga asana practice: Assessment of the risks. J Bodyw Mov Ther. 2019 Jul;23(3):479-488. doi: 10.1016/j.jbmt.2018.09.151. Epub 2018 Oct 24. PubMed
  11. Simon NM, Hofmann SG, Rosenfield D, et al. Efficacy of yoga vs cognitive behavioral therapy vs stress education for the treatment of generalized anxiety disorder: A randomized clinical trial. JAMA Psychiatry. 2021;78(1):13-20. PubMed
  12. Zhu F, Zhang M, Wang D, Hong Q, Zeng C, Chen W. Yoga compared to non-exercise or physical therapy exercise on pain, disability, and quality of life for patients with chronic low back pain: A systematic review and meta-analysis of randomized controlled tri
  13. Makhija A, Khatik N, Raghunandan C. A randomized control trial to study the effect of integrated yoga on pregnancy outcome in hypertensive disorder of pregnancy. Complement Ther Clin Pract. 2021;43:101366. PubMed
  14. Pais M, Pai MV, Kamath A, Bhat R, Bhat P, Joisa GH. A Randomized Controlled Trial on the Efficacy of Integrated Yoga on Pregnancy Outcome. Holist Nurs Pract 2021;35(5):273-280. PubMed
  15. Nayar G, Desai A, Agarwal N, Alan N, Moossy JJ. Cervical arterial dissection and traumatic myelopathy following yoga: surgical case report. Spinal Cord Ser Cases 2022;8(1):46. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Practicing Yoga While Taking Propoxyphene: Common Questions

Is it safe to practice Yoga while taking Propoxyphene?
We do not list a known interaction between Yoga and Propoxyphene. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Yoga and Propoxyphene have any of the same side effects?
Yes — our sources link each of them separately to 4 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Yoga and Propoxyphene used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Yoga in each. That is a conversation for your prescriber, especially if Propoxyphene is being adjusted to a target.
Does Propoxyphene interact with any supplements?
Yes. Propoxyphene has documented interactions with 172 supplements in our database — Yoga is not one of them. The Propoxyphene interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Yoga monograph Uses, safety profile, and every drug interaction in one place Acetaminophen, Butalbital, and Caffeine drug information The full plain-English guide to this medication Propoxyphene supplement interactions Every supplement checked against Propoxyphene, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 19 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Propoxyphene and Yoga?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.