Herb & supplement monograph

Chickweed Drug Interactions, Uses, Effectiveness, Safety & More

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Interaction report

Drugs that interact with Chickweed

0 medications have a known interaction with Chickweed, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Chickweed. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Chickweed combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Chickweed: Uses, Safety & Side Effects

The bottom line

Chickweed is a common edible wild plant traditionally used on the skin for itching and minor irritation, and taken as a tea or tincture for various complaints. Solid human studies are lacking, so its benefits are largely based on tradition rather than proof. It is generally considered low-risk when used short-term, but pregnant and breastfeeding people should avoid it due to limited safety data.

Chickweed
Scientific name
Stellaria media
Family
Caryophyllaceae
Part used
Above-ground parts (leaves, stems, and flowers)
Common forms
Tea, capsules, tincture, dried herb, creams, ointments, salves, poultices
People commonly use it for
  • Skin irritation and itching
  • Minor wounds and cuts
  • Digestive upset
  • Joint and muscle aches
  • Used historically for scurvy
  • Mild diuretic

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Generally considered low-risk for short-term use, but high-quality safety data are limited.

PregnancyLikely Safe

When used orally in the amounts commonly found in foods. There is insufficient reliable information available about the safety of chickweed when used...

Read the full pregnancy detail
BreastfeedingLikely Safe

When used orally in the amounts commonly found in foods. There is insufficient reliable information available about the safety of chickweed when used...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Chickweed (Stellaria media) is a small, low-growing plant with weak, sprawling stems and tiny white, star-shaped flowers. It grows almost everywhere as a common weed in gardens, lawns, fields, and along roadsides across much of the world.

People have eaten the tender leaves and stems in salads and soups for centuries, and it has long been used in folk medicine. It is most often applied to the skin in creams, ointments, and poultices for itching and irritation, or taken by mouth as a tea or tincture.

How it works

Chickweed contains a mix of plant compounds, including saponins, flavonoids, vitamin C, and other antioxidants. These compounds are sometimes credited with soothing, anti-inflammatory, and mild wound-supporting effects.

It is important to know that most of these effects have only been observed in laboratory or test-tube studies. How well these compounds work in the human body, and at what amounts, has not been clearly proven.

Effectiveness

Does Chickweed work?

Evidence overview · 3 uses evaluated
3 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Chickweed, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 3 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Diabetes
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral chickweed for diabetes, there is insufficient reliable information about the clinical effects of chickweed for this purpose.

Insufficient Reliable Evidence To Rate Hyperlipidemia
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral chickweed for hyperlipidemia, there is insufficient reliable information about the clinical effects of chickweed for this purpose.

Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral chickweed for obesity, there is insufficient reliable information about the clinical effects of chickweed for this purpose.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

Chickweed is eaten as a food and is generally thought to be low-risk when used in small amounts for a short time. Still, there are no good long-term safety studies in people.

Be careful not to confuse chickweed with similar-looking plants, since misidentified wild plants can be harmful. People with plant or pollen allergies may react to it. Because chickweed contains saponins, large amounts taken by mouth could cause stomach upset.

Pregnancy and breastfeeding: There is not enough reliable information to know whether chickweed is safe during pregnancy or while breastfeeding. To be safe, avoid it during these times. Always check with your pharmacist or doctor before using chickweed, especially if you have a health condition or take other medicines.

Side effects

When used on the skin or eaten in small food amounts, chickweed is usually well tolerated. Possible side effects include skin irritation or an allergic reaction in sensitive people.

Taken by mouth in large amounts, the saponins in chickweed may cause nausea, stomach upset, diarrhea, or vomiting. Stop using it and seek medical care if you notice signs of an allergic reaction such as rash, swelling, or trouble breathing.

Chickweed: Reported Adverse Effects

Documented safety reports on Chickweed from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Reports by condition
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no established, standardized dose for chickweed. It is sold in many forms, including teas, tinctures, capsules, and skin creams or ointments, and the strength varies widely between products.

If you use a commercial product, follow the directions on the label. Because a proven safe and effective dose has not been set, it is best to start low and check with your pharmacist or doctor before using it, especially by mouth.

Pregnancy & Breastfeeding

Chickweed & Pregnancy

Likely Safe

When used orally in the amounts commonly found in foods. There is insufficient reliable information available about the safety of chickweed when used orally in amounts greater than those found in food; avoid using.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

Chickweed & Breastfeeding

Likely Safe

When used orally in the amounts commonly found in foods. There is insufficient reliable information available about the safety of chickweed when used orally in amounts greater than those found in food; avoid using.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 4 references that drive our Chickweed monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Jovanovic M, Mimica-Dukic N, Poljacki M, Boza P. Erythema multiforme due to contact with weeds: a recurrence after patch testing. Contact Dermatitis 2003;48:17-25. PubMed
  3. Jovanovic, M., Poljacki, M., Mimica-Dukic, N., Boza, P., Vujanovic, Lj, Duran, V., and Stojanovic, S. Sesquiterpene lactone mix patch testing supplemented with dandelion extract in patients with allergic contact dermatitis, atopic dermatitis and non-alle
  4. Poljacki, M., Jovanovic, M., Boza, P., Mimica-Dukic, N., Petrovic, A., and Novovic, Z. [Is Vojvodina a risk area for contact weed allergies?]. Med Pregl. 2005;58(3-4):123-126. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Product directory

Supplement products with Chickweed

277 products in our database contain Chickweed. Open any to see its full ingredient list and every drug interaction we check.

Kidneys & Bladder Hydrate Tincture by Doctor Morse's Healing Herbs Liquid 2 Ounce(s) · 59 mL View ingredients & interactions LiFiber by Unicity Powder 1 Pound(s) · 454 Gram(s) View ingredients & interactions Lung & Bronchial by Christopher's Original Formulas Capsule 100 Vegetarian Cap(s) View ingredients & interactions Lung & Bronchial Formula by Christopher's Original Formulas Liquid 2 fl. Oz. · 59 mL View ingredients & interactions Lung Detox Glycerin by Dr. Morse's Cellular Botanicals Liquid 2 Ounce(s) · 59 mL View ingredients & interactions Lung Detox Tincture by Dr. Morse's Cellular Botanicals Liquid 2 Ounce(s) · 59 Milliliter(s) View ingredients & interactions Lung Detox Tincture by Doctor Morse's Healing Herbs Liquid 2 Ounce(s) · 59 Milliliter(s) View ingredients & interactions Lung Formula by Woodstock Herbal Products Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Lymph Drainage Gentle Mover Tincture by Doctor Morse's Healing Herbs Liquid 2 Ounce(s) · 59 mL View ingredients & interactions Lymphatic System 1 Capsules by Dr. Morse's Cellular Botanicals Capsule 90 Veggiecap(s) View ingredients & interactions Lymphatic System 1 Glycerin by Dr. Morse's Cellular Botanicals Liquid 2 Ounce(s) · 59 mL View ingredients & interactions Lymphatic System 1 Tincture by Dr. Morse's Cellular Botanicals Liquid 2 Ounce(s) · 59 mL View ingredients & interactions MetaboMax Free by Nature's Sunshine Capsule 120 Capsule(s) View ingredients & interactions MetaboMax Plus by Nature's Sunshine Capsule 120 Capsule(s) View ingredients & interactions Metaburn Herbal Weight Formula by Christopher's Original Formulas Capsule 100 Vegetarian Cap(s) View ingredients & interactions Multi-Herb Digestion & Detox Support by Nature's Secret Tablet Or Pill 275 Tablet(s) View ingredients & interactions Multi-Herb Digestion & Detox Support by Nature's Secret Tablet Or Pill 120 Tablet(s) View ingredients & interactions Multi-Herb Digestion & Detox Support by Nature's Secret Tablet Or Pill 36 Tablet(s) View ingredients & interactions Multi-Herb Digestion & Detox Support by Nature's Secret Tablet Or Pill 120 Tablet(s) View ingredients & interactions NatruLAX by Clarify Tablet Or Pill 90 Tablet(s) View ingredients & interactions OC-M by Pure Herbs Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions OC-M by Pure Herbs Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions OC-M by Pure Herbs Capsule 100 Capsule(s) View ingredients & interactions Pancreas Health by Signature Supplements Capsule 100 Capsule(s) View ingredients & interactions
Pharmacist Counseling Corner

Chickweed: Common Questions

What is Chickweed used for, and does it work?
People use Chickweed for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Chickweed interact with prescription medications?
We do not currently list any known drug interactions for Chickweed. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Chickweed interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Chickweed with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Chickweed interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Chickweed used for?
It is most commonly used in skin creams and ointments for itching and minor irritation, and is taken as a tea or tincture for digestive and other complaints. These uses are based mostly on tradition rather than strong scientific proof.
Is Chickweed safe to eat?
The tender leaves and stems have long been eaten in salads and soups and are generally considered safe in food amounts. Just be sure the plant is correctly identified, since some weeds look similar but are not safe.
Can I use Chickweed if I am pregnant or breastfeeding?
It is best to avoid Chickweed during pregnancy and breastfeeding because there is not enough reliable safety information. Talk to your doctor or pharmacist before using it.
Does Chickweed cause side effects?
Most people tolerate it well on the skin or in small food amounts, but it can cause skin irritation or allergic reactions. Taking large amounts by mouth may upset the stomach.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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