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Dietary supplement

Metaburn Herbal Weight Formula Ingredients & Drug Interactions

by Christopher's Original Formulas

Metaburn Herbal Weight Formula label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Metaburn Herbal Weight Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Metaburn Herbal Weight Formula is a dietary supplement by Christopher's Original Formulas with 9 active ingredients. Its ingredients are commonly taken for short-term constipation relief, bowel cleansing before procedures, occasional irregularity.Based on those ingredients, 1,155 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Red Clover, Catnip, Cayenne. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Metaburn Herbal Weight Formula by Christopher's Original Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Metaburn Herbal Weight Formula by Christopher's Original Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Metaburn Herbal Weight Formula by Christopher's Original Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 9 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,275 mg) without saying how much of each component you get.

Metaburn contains nine active herbal ingredients in a proprietary blend: senna leaf (a stimulant laxative), damiana (traditionally used for sexual function), oatstraw (oat extract), juniper berry, red clover, chickweed, catnip, Brigham Tea (Mormon tea), and cayenne pepper. The product is encapsulated in a plant-derived capsule shell.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Oats) (Natural Medicines).
  • On file: Postherpetic neuralgia — rated "Likely Effective" (Capsicum) (Natural Medicines).
  • On file: Dyslipidemia — rated "Likely Effective" (Oats) (Natural Medicines).
  • On file: Diabetic neuropathy — rated "Likely Effective" (Capsicum) (Natural Medicines).
  • On file: Constipation — rated "Likely Effective" (Senna) (Natural Medicines).

The evidence is mixed and sparse for most claims. Senna is likely effective for constipation and possibly effective for bowel preparation—it's a proven laxative.

Oatstraw is likely effective for managing cholesterol (dyslipidemia) and coronary heart disease risk. Cayenne is likely effective for nerve pain after shingles (postherpetic neuralgia) and diabetic nerve pain, and possibly effective for cluster headaches, back pain, and nausea after surgery.

For the other ingredients—damiana, juniper, red clover, chickweed, and catnip—we don't hold evidence strong enough to rate them for any condition. The product as a whole is not proven for weight loss in the data we have.

The evidence, ingredient by ingredient Senna Damiana Oats Juniper Red Clover Chickweed Catnip Mormon Tea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 9 of the 9 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 9.
  • General safety write-ups exist for 9 of 9.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Senna is generally well tolerated short-term but not for long-term daily use without medical guidance; common side effects are abdominal pain, cramps, diarrhea, and nausea. Damiana, juniper, catnip, and chickweed have limited human safety data.

Oatstraw as food is safe in pregnancy and lactation, though concentrated supplements are less studied. Damiana and juniper should be avoided in pregnancy and lactation due to insufficient safety data.

Catnip may stimulate the uterus and should be avoided in pregnancy. Cayenne in food amounts is likely safe in pregnancy and lactation, but concentrated doses aren't well studied.

Brigham Tea has no reliable pregnancy or lactation data and should be avoided. Red clover is possibly unsafe in lactation despite being rated possibly safe in pregnancy; avoid it while breastfeeding.

Cayenne can cause burning, bloating, diarrhea, and gastrointestinal discomfort; oatstraw may cause bloating and gas.

Side effects, ingredient by ingredient Senna Damiana Oats Juniper Red Clover Chickweed Catnip Mormon Tea

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 7 of the 9 matched ingredients can interact with medications — Red Clover, Senna, Damiana, Juniper, Oats, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 1,156 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Metaburn, check with your doctor or pharmacist if you take blood thinners (warfarin, antiplatelet drugs), diabetes or insulin medications, diuretics, digoxin, estrogen therapy, tamoxifen, methotrexate, sedatives (CNS depressants), lithium, theophylline, aspirin, ACE inhibitors, or ciprofloxacin. Several ingredients—senna, damiana, oatstraw, juniper, and cayenne—can raise low blood sugar risk; senna and cayenne may increase bleeding or interfere with hormone therapy; and catnip may affect lithium levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a multi-ingredient herbal blend with proven benefit mainly for constipation (from senna) and nerve pain (from cayenne). If you take blood thinners, diabetes medications, heart drugs, lithium, or sedatives, talk with your doctor or pharmacist before using it—several ingredients interact with these drug classes.

Pregnancy and breastfeeding require extra caution: damiana, juniper, and catnip should be avoided. Work through your medication list with your own healthcare provider before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 9 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Metaburn Herbal Weight Formula, straight from the product label.

Brand Christopher's Original Formulas
Barcode (UPC) 084783891734
Net contents 100 Vegetarian Cap(s)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 200486
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Metaburn Herbal Weight Formula by Christopher's Original Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
33
UPC/BARCODE
084783891734
IngredientAmount% DV
Senna0 NP--
Damiana0 NP--
Oatstraw0 NP--
Proprietary Blend1275 mg--
Juniper0 NP--
Red Clover0 NP--
Chickweed0 NP--
Catnip0 NP--
Brigham Tea0 NP--
Cayenne0 NP--

Other ingredients: plant-derived Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommendation: As a dietary supplement, take 3 capsules 2 times a day, with meals or a glass of water, or as directed by your health care professional. Avoid product usage after 2:00 p.m.

Precautions

Avoid product usage after 2:00 p.m.

Storage

Store in a cool dry place.

Brand IP Statement(s)

2010 Wholistic Botanicals L.L.C. All Rights Reserved

John R. Christopher

FDA Statement of Identity

Dietary Supplement

General Statements

425 mg each

Formulation

No Fillers or Chemicals.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Metaburn Herbal Weight Formula by Christopher's Original Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Metaburn Herbal Weight Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Metaburn Herbal Weight Formula by Christopher's Original Formulas

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container33 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1275 mg per serving

Other (inactive) ingredients: Plant-derived Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Metaburn Herbal Weight Formula by Christopher's Original Formulas Drug Interactions

Want to check YOUR meds against Metaburn Herbal Weight Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,155Drugs
581 Moderate 574 Minor

Ingredients driving the most interactions

Red Clover 867
Catnip 248
Cayenne 239
Juniper 162
Senna 140

Individual Drug Interactions

The ingredients in Metaburn Herbal Weight Formula interact with 1,155 drugs. Click any drug to see the details.

7 of the 9 ingredients in Metaburn Herbal Weight Formula interact with drugs. Each result below shows which ingredient is responsible. Red Clover Catnip Cayenne Juniper Senna Damiana Oatstraw

Each ingredient & the kinds of drugs it affects

For each ingredient in Metaburn Herbal Weight Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Red Clover9 drug types · 867 drugs

Estrogens

Theoretically, concomitant use of large amounts of red clover might interfere with estrogen therapy.
Red clover contains phytoestrogens which might have estrogenic activity in some people. Theoretically, red clover might compete for estrogen receptors and interfere with estrogen-containing drug therapy.

Likelihood Probable Evidence D
Methotrexate (Trexall, Others)

Theoretically, red clover might increase the risk of methotrexate toxicity.
In a case report, a 52-year-old female receiving weekly methotrexate injections for psoriasis developed symptoms of methotrexate toxicity, including severe vomiting and epigastric pain, after three days of taking red clover 430 mg daily. Toxicity resolved after red clover was discontinued. However, no liver function tests or methotrexate levels were reported.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, the phytoestrogens in red clover might interfere with tamoxifen.
In vitro and animal research suggests that genistein, a constituent of red clover, might antagonize the antitumor effects of tamoxifen. However, there is some evidence from an animal study that red clover does not reduce the efficacy of tamoxifen. Until more is known, tell patients taking tamoxifen to avoid red clover.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Although some laboratory research suggests that red clover may have anticoagulant and antiplatelet activity, clinical research has not shown this effect.
In vitro research suggests that genistein in red clover has antiplatelet effects, and historically, red clover was thought to have anticoagulant effects due to its coumarin content. However, some experts state that this is unlikely as most natural coumarins have not been shown to have anticoagulant effects, and their content in red clover is low. Additionally, some clinical research in postmenopausal patients found no effect on coagulation or prothrombin time with the use of red clover flowering tops 378 mg daily for 12 months or red clover isoflavone (Rimostil) 50 mg daily for 2 years.

Likelihood Unlikely Evidence B
Caffeine

Theoretically, soy might reduce the clearance of caffeine; however, a small clinical study found no effect.
Red clover contains genistein. Taking genistein 1 gram daily for 14 days seems to inhibit caffeine clearance and metabolism in healthy females. However, this effect does not seem to occur with the lower amounts of genistein found in red clover. A clinical study in healthy postmenopausal individuals shows that taking red clover capsules standardized to contain 60 mg isoflavones twice daily for 14 days does not affect the pharmacokinetics of caffeine.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, red clover might increase levels of drugs metabolized by CYP1A2; however, a small clinical study found no effect.
In vitro evidence shows that red clover inhibits CYP1A2. However, a clinical study in healthy postmenopausal individuals shows that taking red clover capsules standardized to contain 60 mg isoflavones twice daily for 14 days does not affect the pharmacokinetics of caffeine, a CYP1A2 probe substrate.

Likelihood Unlikely Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, red clover might increase the levels and clinical effects of drugs metabolized by CYP2C19.
In vitro evidence suggests that red clover weakly inhibits CYP2C19. This interaction has not been reported in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, red clover might increase levels of drugs metabolized by CYP2C9; however, a small clinical study found no effect.
In vitro evidence suggests that red clover might inhibit CYP2C9. However, a clinical study in healthy postmenopausal individuals shows that taking red clover capsules standardized to contain 60 mg isoflavones twice daily for 14 days does not affect the pharmacokinetics of tolbutamide, a CYP2C9 probe substrate.

Likelihood Unlikely Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, red clover might increase levels of drugs metabolized by CYP3A4; however, a small clinical study found no effect.
In vitro evidence shows that red clover might inhibit CYP3A4 isoenzymes. However, a clinical study in healthy postmenopausal individuals shows that taking red clover capsules standardized to contain 60 mg isoflavones twice daily for 14 days does not affect the pharmacokinetics of alprazolam, a CYP3A4 probe substrate.

Likelihood Unlikely Evidence B
Red Clover full monograph & interactions

Catnip2 drug types · 248 drugs

Cns Depressants

Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Clinical and animal research shows that catnip has sedative properties.

Likelihood Possible Evidence D
Lithium

Theoretically, catnip might reduce excretion and increase levels of lithium.
Catnip is thought to have diuretic properties which might reduce lithium excretion. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Catnip full monograph & interactions

Cayenne6 drug types · 239 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, capsicum may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro research shows that capsicum might increase the effects of antiplatelet drugs. Also, population research shows that capsicum is associated with an increased risk of self-reported bleeding in patients taking warfarin. However, clinical research shows that taking a single dose of capsaicin (Asian Herbex Ltd.), the active ingredient in capsicum, 400-800 mcg orally in combination with aspirin 500 mg does not decrease platelet aggregation when compared with taking aspirin 500 mg alone. Also, there was no notable effect on measures of platelet aggregation with capsaicin. It is unclear whether capsaicin must be used in more than a single dose to affect platelet aggregation.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, taking capsicum with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical research shows that consuming capsicum 5 grams along with a glucose drink attenuates the rise in plasma glucose after 30 minutes by 21%, decreases the 2-hour postprandial area under the curve of plasma glucose by 11%, and increases the 2-hour postprandial area under the curve of plasma insulin by 58% in healthy individuals when compared with placebo. Other clinical research shows that taking capsicum 5 mg daily for 28 days significantly reduces postprandial blood glucose and insulin levels, but not fasting blood glucose and insulin levels, in patients with gestational diabetes.

Likelihood Possible Evidence B
Aspirin

Theoretically, taking capsicum with aspirin might reduce the bioavailability of aspirin.
Animal research shows that acute or chronic intake of capsicum pepper reduces oral aspirin bioavailability. This has not been shown in humans.

Likelihood Possible Evidence D
Theophylline

Theoretically, taking capsicum with theophylline might increase the levels and adverse effects of theophylline.
In animal research, oral administration of capsicum reduced excretion of theophylline. However, capsicum does not seem to affect the pharmacokinetics of theophylline when administered intravenously.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, using topical capsaicin may increase the risk of ACE inhibitor-induced cough.
There is one case report of a topically applied capsaicin cream contributing to the cough reflex in a patient using an ACEI. However, it is unclear if this interaction is clinically significant.

Likelihood Unlikely Evidence D
Ciprofloxacin (Cipro)

Theoretically, taking capsicum with ciprofloxacin might increase levels and adverse effects of ciprofloxacin.
Animal research shows that concomitant use of capsaicin, the active constituent of capsicum, and ciprofloxacin increases the bioavailability of ciprofloxacin by up to 70%.

Likelihood Possible Evidence D
Cayenne full monograph & interactions

Juniper3 drug types · 162 drugs

Antidiabetes Drugs

Theoretically, taking juniper berry with antidiabetes medications might cause additive hypoglycemia.
Animal research shows that juniper berry can lower blood glucose.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, juniper berry might increase the risk of adverse effects from diuretic drugs.
Juniper berry is thought to have mild diuretic effects.

Likelihood Possible Evidence D
Lithium

Theoretically, juniper berry might reduce lithium excretion and increase serum levels of lithium.
Juniper berry is thought to have mild diuretic effects.

Likelihood Possible Evidence D
Juniper full monograph & interactions

Senna5 drug types · 140 drugs

Digoxin (Lanoxin)

Theoretically, senna might increase the risk of adverse effects when taken with digoxin.
Overuse/abuse of senna increases the risk of adverse effects from cardiac glycosides, such as digoxin, due to potassium depletion.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of senna might compound diuretic-induced potassium loss and increase the risk for hypokalemia.

Likelihood Possible Evidence D
Estrogens

Theoretically, taking senna may interfere with the absorption of exogenous estrogens.
Some preliminary clinical evidence suggests that senna reduces the absorption of estradiol and decreases serum concentrations of estrone and estrone sulfate by decreasing intestinal transit time.

Likelihood Possible Evidence B
Stimulant Laxatives

Theoretically, senna might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Senna is a stimulant laxative; concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, excessive use of senna might increase the effects of warfarin.
Senna has stimulant laxative effects and can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. In one case report, excessive use of senna for 3 weeks resulted in diarrhea, bloody stools, and an elevated INR of 11.9.

Likelihood Possible Evidence D
Senna full monograph & interactions

Damiana1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
Damiana full monograph & interactions

Oatstraw2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Consuming oats can decrease blood glucose in patients with diabetes. In those who require insulin, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence D
Insulin

Concomitant use of oats and insulin might increase the risk of hypoglycemia.
In patients with insulin-dependent type 2 diabetes, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence B
Oatstraw full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Metaburn Herbal Weight Formula, from the product label.

Christopher's Original Formulas

See all Christopher's Original Formulas products
Name
Wholistic Botanicals L.L.C.
City
Spanish Fork
State
UT
ZipCode
84660
Phone Number
1-800-453-1406
Web Address
www.drchristopher.com
Pharmacist Counseling Corner

Metaburn Herbal Weight Formula by Christopher's Original Formulas: Common Questions

Does Metaburn Herbal Weight Formula by Christopher's Original Formulas interact with any medications?
Yes. Based on its ingredients, Metaburn Herbal Weight Formula has a known interaction with 1,155 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Metaburn Herbal Weight Formula contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm on blood thinners?
No—not without checking first. Senna can increase diarrhea, which raises warfarin's effect and bleeding risk (Moderate severity). Cayenne also has a Moderate interaction with blood thinners. Talk to your doctor or pharmacist before starting.
Can I take it if I have diabetes or take insulin?
Not without medical approval. Damiana, oatstraw, juniper, and cayenne all lower blood sugar, so taking them with diabetes drugs or insulin raises your risk of low blood sugar (hypoglycemia). Your doctor may need to adjust your dose.
Is senna in here safe to use long-term?
No. Senna is approved for short-term use only—not for daily long-term use without medical guidance. Overuse can deplete potassium and cause serious side effects. Use it only as directed and for short periods.
Can I use this while pregnant or breastfeeding?
Ask your doctor. Damiana, juniper, and catnip should be avoided during pregnancy and lactation because safety is not established. Red clover is possibly unsafe while breastfeeding. Senna, oatstraw, and cayenne in food amounts may be acceptable, but this is a concentrate—your healthcare provider needs to weigh the risks.
What does this product actually do?
The strongest evidence is for senna—it works as a laxative for constipation and bowel prep. Cayenne is proven for nerve pain. Oatstraw may help with cholesterol. For weight loss, the other ingredients (damiana, juniper, red clover, chickweed, catnip, Brigham Tea), we don't have evidence strong enough to rate them.
What are the most common side effects?
From senna: abdominal cramping, diarrhea, nausea, and discomfort. From oatstraw: bloating, gas, and flatulence. From cayenne: burning sensation, diarrhea, heartburn, and gastrointestinal upset. Starting slowly can reduce these.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Metaburn Herbal Weight Formula label
Go deeper

The Full Monographs Behind Metaburn Herbal Weight Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Senna

Interacts with 140 drugs

Senna is a plant-based stimulant laxative that is widely used and generally effective for short-term relief of constipation. It is best used occasionally and for only a few days at a time, s...

Read the full Senna monograph → Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph → Herb & supplement monograph

Oats

Interacts with 86 drugs

Oats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a food, oats are safe for most people, and...

Read the full Oats monograph → Herb & supplement monograph

Juniper

Interacts with 162 drugs

Juniper berry is a traditional herb best known for flavoring gin and for its folk use as a diuretic and digestive aid. Solid human evidence for its health benefits is limited, and it can irr...

Read the full Juniper monograph → Herb & supplement monograph

Red Clover

Interacts with 867 drugs

Red clover is a plant rich in isoflavones (plant compounds with weak estrogen-like activity) that is most often used for menopause symptoms like hot flashes. The evidence is mixed and genera...

Read the full Red Clover monograph → Herb & supplement monograph

Chickweed

Chickweed is a common edible wild plant traditionally used on the skin for itching and minor irritation, and taken as a tea or tincture for various complaints. Solid human studies are lackin...

Read the full Chickweed monograph → Herb & supplement monograph

Catnip

Interacts with 248 drugs

Catnip is a mint-family herb most often used as a calming tea for sleep, anxiety, and minor digestive upset, but solid human research supporting these uses is lacking. It is generally consid...

Read the full Catnip monograph → Herb & supplement monograph

Mormon Tea

Mormon Tea is a traditional Southwestern desert beverage made from a North American Ephedra plant that, unlike Asian ephedra, is generally thought to lack ephedrine. There is very little mod...

Read the full Mormon Tea monograph → Herb & supplement monograph

Capsicum

Interacts with 239 drugs

Capsicum (chili pepper) contains capsaicin, which is best known and best studied as a topical treatment for certain types of pain. Topical capsaicin products are supported by reasonable evid...

Read the full Capsicum monograph →
Sources

Sources & How We Checked

Metaburn Herbal Weight Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 190 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Senna 42 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. American Academy of Pediatrics. The transfer of drugs and other chemicals into human milk. Pediatrics 2001;108:776-89. PubMed
  4. Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
  5. Seybold U, Landauer N, Hillebrand S, Goebel FD. Senna-induced hepatitis in a poor metabolizer. Ann Intern Med 2004;141:650-1. PubMed
  6. Vanderperren B, Rizzo M, Angenot L, et al. Acute liver failure with renal impairment related to the abuse of senna anthraquinone glycosides. Ann Pharmacother 2005;39:1353-7. PubMed
  7. Xing JH, Soffer EE. Adverse effects of laxatives. Dis Colon Rectum 2001;44:1201-9. PubMed
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Damiana 2 references
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Juniper 7 references
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Chickweed 4 references
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Mormon Tea 2 references
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Capsicum 89 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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