Herb & supplement monograph

Yellow Dock Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by ·Updated July 2026
What is this page for?

First and foremost: how Yellow Dock interacts with medications. The heart of this page is the interaction list — every drug Yellow Dock is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Yellow Dock is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

Check Yellow Dock against your medication

Add one medication
Yellow Dock
+
Start typing any prescription or over-the-counter drug name.
Reviewed by licensed pharmacists Sourced from Natural Medicines
On this page

Yellow Dock Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, Yellow Dock drug interactions carry a meaningful risk for people taking certain heart or fluid medications, especially when the supplement is used long-term or in large amounts. Nearly all of the listed interactions are rated major, driven by yellow dock's potential to lower potassium with chronic or heavy use.

Interactions deserving the most attention

The interactions that matter most involve digoxin and diuretics (water pills). Used heavily or over time, yellow dock may lower potassium levels, which can raise the risk of digoxin toxicity and add to the potassium loss diuretics already cause. There is also a weaker, theoretical concern with warfarin: in large amounts, yellow dock acts as a mild laxative, and the resulting diarrhea could increase warfarin's effect and the chance of bleeding.

What the rest of the list means

The long list of interacting medications mostly reflects one shared issue, potassium loss, spread across the many diuretic drugs available. These effects are predicted from how yellow dock works in the body rather than confirmed in human interaction studies, and they mainly apply to chronic or high-dose use rather than occasional use in typical amounts.

Check your medications against Yellow Dock

Based on HelloPharmacist’s Yellow Dock interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Yellow Dock

78 medications have a known interaction with Yellow Dock, graded by severity. Select any drug for the full evidence-based detail.

76 major interactions. These combinations can be clinically significant — best avoided, or used only with close professional supervision. Always check with your pharmacist before combining them with Yellow Dock.

2,830 drugs
Acetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual› Acetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES› AcetazolamideAk-Zol, Diamox› Amiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic› Ammonium ChlorideAmmonium Chloride› Atenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic› Atenolol, ChlorthalidoneTenoretic› Azilsartan, ChlorthalidoneEdarbyclor› Benazepril, HydrochlorothiazideLotensin HCT› BendroflumethiazideAprinox, Naturetin, Neo-NaClex› Bendroflumethiazide, NadololCorzide› Bendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K› Bendroflumethiazide, Rauwolfia SerpentinaRauzide› BenzthiazideExna› Bisoprolol, HydrochlorothiazideZiac› BumetanideBurinex› Bumetanide, PotassiumBurinex K› Caffeine, Potassium Salicylate, SalicylamideTrim-Elim› Candesartan Cilexetil, HydrochlorothiazideAtacand HCT› Captopril, HydrochlorothiazideAcezide, Capozide› ChlorothiazideDiuril› Chlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250› Chlorothiazide, ReserpineDiupres› ChlorthalidoneHygroton, Thalitone› Chlorthalidone, ClonidineClorpres, Combipres› Cryptenamine, MethyclothiazideDiutensen› CyclothiazideAnhydron, Fluidil› Deserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte› Deserpidine, MethyclothiazideEnduronyl, Enduronyl Forte› DigoxinDigitek, Lanoxicaps, Lanoxin›
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Yellow Dock combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Yellow Dock affects

Every type of medication (drug category) Yellow Dock is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 3 drug categories Yellow Dock interacts with
Digoxin (lanoxin)Diuretic DrugsWarfarin (coumadin)
Digoxin (Lanoxin)

Theoretically, yellow dock might increase the risk of digoxin toxicity when used long-term or in large amount.
When yellow dock is used chronically or in large amounts, hypokalemia may occur. This might increase the toxic effects of digoxin.

Likelihood Probable Evidence D
Diuretic Drugs

Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.
When yellow dock is used chronically or in large amounts, hypokalemia may occur, and overuse of yellow dock might compound diuretic-induced potassium loss.

Likelihood Probable Evidence D
Warfarin (Coumadin)

Theoretically, the laxative effects of yellow dock might increase the effects of warfarin, including the risk of bleeding.
The anthraquinones in yellow dock have a mild stimulant laxative effect. Consuming excessive amounts can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding.

Likelihood Possible Evidence D
Monograph

Yellow Dock: Uses, Safety & Side Effects

Medically reviewed by · Reviewed July 2026 ·
The bottom line

Yellow dock is a traditional herb used mostly as a mild laxative and a digestive and skin tonic. Good-quality human studies are lacking, so its benefits are largely unproven, and its naturally occurring oxalates and anthraquinones mean it should be used cautiously and not long-term.

Scientific name
Rumex crispus
Family
Polygonaceae
Part used
Root (rhizome); leaves are sometimes used
Common forms
Capsules, tinctures, liquid extracts, dried root for tea, and sometimes topical ointments
People commonly use it for
  • Constipation
  • Digestive support
  • Skin conditions
  • Iron-deficiency or 'blood-building' tonic
  • Liver and detox support

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

May act as a laxative and contains oxalates; use short-term and with care.

PregnancyPossibly Unsafe

When used orally; avoid using. Yellow dock contains anthraquinone glycosides; unstandardized laxatives are not desirable during pregnancy.

Read the full pregnancy detail
BreastfeedingPossibly Unsafe

When used orally; avoid using. Anthraquinones are secreted into breast milk.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Yellow dock (Rumex crispus) is a flowering plant in the buckwheat family. It is also sometimes called curly dock because of its wavy-edged leaves. It grows as a common weed in fields, roadsides, and disturbed soil across North America, Europe, and many other parts of the world.

The part most often used is the deep yellow root. People dry and grind it for teas, or take it as capsules, tinctures, and liquid extracts. In folk and traditional herbal practice, yellow dock has long been used as a gentle laxative and as a general tonic for digestion, the skin, and the liver.

How it works

Yellow dock root contains anthraquinone compounds, which are the same general type of substance found in other plant laxatives like senna. These may stimulate the bowel and produce a laxative effect. The root also has bitter compounds that may stimulate digestive juices, and tannins that have an astringent (tightening) action.

The root contains some iron, which is part of why it is traditionally used as a "blood-building" tonic, though the amount and how well the body absorbs it are not well established.

Most of these effects are based on laboratory studies, animal research, or traditional reasoning rather than solid human trials, so they should be viewed as proposed mechanisms, not proven ones.

Effectiveness

Does Yellow Dock work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by .

Evidence overview · 2 uses evaluated
2 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Yellow Dock, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 2 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Diabetes
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral yellow dock for diabetes, there is insufficient reliable information about the clinical effects of yellow dock for this purpose.

Insufficient Reliable Evidence To Rate Iron deficiency anemia
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral yellow dock for iron deficiency anemia, there is insufficient reliable information about the clinical effects of yellow dock for this purpose.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

Yellow dock is best thought of as a short-term herb rather than something to take daily for long periods. Like other laxative herbs that contain anthraquinones, frequent or long-term use can lead to dependence on the laxative effect and to electrolyte loss.

The plant also naturally contains oxalates. People with a history of kidney stones, kidney disease, or gout should be especially cautious or avoid it, since oxalates can contribute to certain stones. Very large amounts of oxalate-containing plants have rarely been linked to poisoning.

People with bowel conditions such as inflammatory bowel disease, blockage, or unexplained abdominal pain should not use laxative herbs without medical advice. Pregnant and breastfeeding women should avoid yellow dock because there is not enough safety information and the laxative compounds may not be appropriate. Do not give it to children unless a healthcare provider recommends it.

Side effects

The most common side effects relate to its laxative action and may include cramping, loose stools, diarrhea, and nausea. Overuse can lead to dehydration and loss of important minerals like potassium.

Because of its oxalate content, large or prolonged use could theoretically raise the risk of kidney stones in some people. Allergic reactions are possible but uncommon. Stop using it and seek medical care if you have severe stomach pain, persistent vomiting, signs of an allergic reaction, or symptoms of dehydration.

Yellow Dock: Reported Adverse Effects

Documented safety reports on Yellow Dock from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, yellow dock seems to be well tolerated when properly prepared and consumed in food amounts. Consuming raw yellow dock leaves or rhizomes may be unsafe.

Serious Adverse Effects (Rare):

Orally: Raw leaves or rhizomes can cause hypocalcemia, kidney stones, and vomiting.

Reports by condition
Depression Pulmonary/Respiratory

Orally, yellow dock has been linked to respiratory depression and death after ingestion of 500 grams. Oxalic acid, a constituent of yellow dock, reacts with calcium in plasma, forming insoluble calcium oxalate, which can cause hypocalcemia; the crystals may precipitate in the lungs. Older or uncooked leaves should be avoided.

  1. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
Dermatitis Dermatologic

Orally, yellow dock can cause dermatitis when consumed in large amounts. Topically, contact with the plant may cause dermatitis in people sensitive to yellow dock.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
Diarrhea Gastrointestinal

Orally, vomiting may occur after ingestion of fresh rhizome. Consuming excessive amounts can cause diarrhea and nausea. Excessive use can also cause abdominal cramps and intestinal atrophy. There is one report of a death, preceded by vomiting and diarrhea, after ingestion of 500 grams of yellow dock. Older or uncooked leaves should be avoided.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  4. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
Fatigue Hematologic

Orally, in one case report, a 38-year-old female developed immune-mediated thrombocytopenia after consuming a "cleansing" tea containing unknown amounts of yellow dock and burdock. The patient presented with bruising, mild weakness, and fatigue, which started 2-3 days after consuming the tea, and was found to have a platelet count of 5,000 per mcL. Symptoms resolved after platelet transfusion and treatment with oral dexamethasone. It is unclear if these effects were caused by yellow dock, burdock, the combination, or other contributing factors.

  1. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247.
Hypocalcemia Other

Orally, yellow dock can cause hypokalemia when taken in large amounts. There is one report of a death, preceded by severe metabolic acidosis, after ingestion of 500 grams of yellow dock. Oxalic acid, a constituent of yellow dock, reacts with calcium in plasma, forming insoluble calcium oxalate, which can cause hypocalcemia; the crystals may precipitate in the kidneys, blood vessels, heart, lungs, and liver. Older or uncooked leaves should be avoided.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
Hypocalcemia Hepatic

Orally, yellow dock has been linked to liver failure and death after ingestion of 500 grams. Oxalic acid, a constituent of yellow dock, reacts with calcium in plasma, forming insoluble calcium oxalate, which can cause hypocalcemia; the crystals may precipitate in the liver. Older or uncooked leaves should be avoided.

  1. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
Hypocalcemia Cardiovascular

Orally, yellow dock has been linked to ventricular fibrillation and death after ingestion of 500 grams. Oxalic acid, a constituent of yellow dock, reacts with calcium in plasma, forming insoluble calcium oxalate, which can cause hypocalcemia; the crystals may precipitate in the blood vessels and heart. Older or uncooked leaves should be avoided.

  1. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
Hypocalcemia Renal

Orally, yellow dock can cause polyuria when consumed in large amounts. There is one report of a death, preceded by kidney failure, after ingestion of 500 grams. Oxalic acid, a constituent of yellow dock, reacts with calcium in plasma, forming insoluble calcium oxalate, which can cause hypocalcemia; the crystals may precipitate in the kidneys. Individuals with a history of kidney stones should use yellow dock cautiously. Older or uncooked leaves should be avoided.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no official or standardized dose for yellow dock, and product strengths vary widely between teas, tinctures, and capsules. Because of this, the safest approach is to follow the directions on the product label and not exceed them.

Use it for the shortest time needed rather than as a long-term daily supplement. Before starting yellow dock—especially if you take other medicines or have a health condition—check with a pharmacist or doctor to make sure it is appropriate for you.

Pregnancy & Breastfeeding

Yellow Dock & Pregnancy

Possibly Unsafe

When used orally; avoid using. Yellow dock contains anthraquinone glycosides; unstandardized laxatives are not desirable during pregnancy.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

Yellow Dock & Breastfeeding

Possibly Unsafe

When used orally; avoid using. Anthraquinones are secreted into breast milk.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 8 references that drive our Yellow Dock monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  5. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  6. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  7. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  8. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Yellow Dock

202 brands in our database make a supplement containing Yellow Dock.

Product directory

Supplement products with Yellow Dock

765 products in our database contain Yellow Dock. Open any to see its full ingredient list and every drug interaction we check.

#3 - GB-LIV by Nutri-West Herbals Tablet Or Pill 100 Tablet(s) View ingredients & interactions 14 Day Teatox by Teatox Life Other (e.g. Tea Bag) 2.45 Ounce(s) · 70 Gram(s) View ingredients & interactions Acne Flormula by TerraVita Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Acne Formula 450 mg by TerraVita Premium Collection Capsule 100 Capsule(s) View ingredients & interactions Acne Formula Chocolate Flavor by TerraVita Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Acne Formula Mint Flavor by TerraVita Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Acne Formula Powder by TerraVita Premium Collection Powder 4 Ounce(s) View ingredients & interactions Acne Formula Powder by TerraVita Premium Collection Powder 1 Ounce(s) View ingredients & interactions Acne Formula Strawberry Flavor by TerraVita Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Acne Formula Vanilla Flavor by TerraVita Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions AcneAdvance by Futurebiotics Tablet Or Pill 90 Vegetarian Tablet(s) View ingredients & interactions AcneAdvance with Colustrum by Futurebiotics Tablet Or Pill 90 Vegetarian Tablet(s) View ingredients & interactions ACP Vitamin ACP by Systemic Formulas Bio Nutriment Capsule 60 Capsule(s) View ingredients & interactions All Cell Detox by Nature's Sunshine Capsule View ingredients & interactions AM - PM Power Cleanse Herb Blend Formula by The Vitamin Shoppe Tablet Or Pill 120 Tablet(s) View ingredients & interactions AM Packet, NOON Packet by Nature's Sunshine Capsule 42 Packet(s) · 14 AM, NOON, PM Packet(s) View ingredients & interactions ATAK Immune Rejuvenator by Systemic Formulas Bio Challenge Capsule 60 Capsule(s) View ingredients & interactions B-Complete by Simply Young Powder 114 Gram(s) · 4.04 Ounce(s) View ingredients & interactions B-Complex by Catie's Capsule 150 V Capsule(s) View ingredients & interactions B-Complex Powder by Catie's Powder 89 Gram(s) · 2.89 Ounce(s) View ingredients & interactions Balance by Herbally Grounded Liquid 4 Fluid Ounce(s) · 118 mL View ingredients & interactions BC-W by Pure Herbs Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions BC-W by Pure Herbs Liquid 4 Fluid Ounce(s) · 120 mL View ingredients & interactions Berry DeTox by Yogi Other (e.g. Tea Bag) 16 Tea Bag(s) · 1.12 Oz(s) · 32 Gram(s) View ingredients & interactions
Pharmacist Counseling Corner

Yellow Dock: Common Questions

What is Yellow Dock used for, and does it work?
People use Yellow Dock for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Yellow Dock interact with prescription medications?
Yes. We list 78 medications with a known interaction with Yellow Dock, including 76 rated major. Use the checker above to see how Yellow Dock interacts with a specific drug.
How are Yellow Dock interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Yellow Dock with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Yellow Dock interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Yellow Dock used for?
It is traditionally used as a mild laxative for constipation and as a tonic for digestion, the skin, and iron support. These uses are based mostly on tradition, and strong human evidence is lacking.
Is Yellow Dock safe to take?
It may be acceptable for short-term use in healthy adults, but it acts as a laxative and contains oxalates. People with kidney stones, kidney disease, gout, or bowel problems should be cautious or avoid it, and it should not be used long-term without medical advice.
Can I take Yellow Dock while pregnant or breastfeeding?
No. Because of the lack of safety data and its laxative compounds, it is best to avoid Yellow Dock during pregnancy and while breastfeeding.
Does Yellow Dock help with low iron or anemia?
The root contains a small amount of iron and is traditionally used as a "blood builder," but there is no solid proof it treats iron-deficiency anemia. If you have low iron, talk to your doctor about tested treatments.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Keep exploring

Products that contain Yellow Dock

A rotating sample of real supplements in our database that list Yellow Dock — open any to see its full ingredients and every drug interaction we check.

See all 765 products with Yellow Dock →
Where next
Supplement interaction checkerCheck any supplement or product against your medications Drug–drug interactionsCheck two or more of your medications against each other Browse medications A–ZEvery drug we’ve checked against herbs & supplements NDC & pricing lookupFind a drug’s NDCs, packaging and costs Ask a pharmacistFree, personal answer from our licensed team

Have a question about Yellow Dock?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist