What Supplements Interact with Brincidofovir?
Brincidofovir brand name: Tembexa. Every interaction below applies to the brands too.
Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy
What is this page for?
One answer, for one medication: what supplements and herbal products interact with Brincidofovir? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.
This page covers supplement interactions only — to check Brincidofovir against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy
34 supplements and herbal ingredients have interactions with Brincidofovir on file in the HelloPharmacist interaction database — 4 rated major, 15 moderate, and 15 minor. The most serious involve Apple, Grapefruit, Sweet Orange and Activated Charcoal.
Our assessment: with 4 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Brincidofovir.
Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.
This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓
Brincidofovir: Top Interactions at a Glance
The most significant Brincidofovir supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.
Showing the 12 highest-ranked of 34 interacting ingredients — plus 1,418 more checked with no known interaction. See the complete ranked list.
The Major Interactions to Know About
The most clinically significant Brincidofovir + supplement combinations in our database, best-documented first. Open any card for the full report.
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full interaction Major Likelihood Likely Grapefruit + BrincidofoviriGrapefruit juice can decrease levels of drugs that are substrates of OATP.
Read the full interaction Major Likelihood Likely Sweet Orange + BrincidofoviriConsuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full interaction Major Likelihood Probable Activated Charcoal + BrincidofoviriActivated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full interactionEvery Supplement Checked Against Brincidofovir
All 1,452 ingredients in our database, ranked by severity — 34 with a Brincidofovir interaction on file and 1,418 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.
Looking for an interaction with a specific supplement product? Search products instead ↓
No ingredients match “”.
AppleMalus Domestica, abilde, almindelig Aeble, +25 more Likely
What it is: Apples are a nutritious whole food that provides fiber, vitamins, and antioxidant plant compounds, and eating them regularly fits well into...
Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Read the full Apple + Brincidofovir interactionGrapefruitCitrus Paradisi Likely
What it is: Grapefruit is a nutritious citrus fruit rich in vitamin C and other nutrients, and it is generally safe to eat.
Grapefruit juice can decrease levels of drugs that are substrates of OATP.
Read the full Grapefruit + Brincidofovir interactionSweet OrangeCitrus Sinensis, blood Orange, citri Sinensis, +14 more Likely
What it is: Sweet orange is a common citrus fruit that is a good source of vitamin C, fiber, and antioxidants, and is enjoyed as a food worldwide.
Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Read the full Sweet Orange + Brincidofovir interactionActivated CharcoalActivated Carbon, animal Charcoal, carbo Vegetabilis, +13 more Probable
What it is: Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some...
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Brincidofovir interactionCoffee CharcoalCafé Arabica, café Carbonisé, café Robusta, +5 more Probable
What it is: Coffee charcoal is made by roasting green coffee beans until they turn black, creating a charcoal-like material used traditionally for diarr...
Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two hours.
Read the full Coffee Charcoal + Brincidofovir interactionEuropean MandrakeMandragora Officinarum, alraunwurzel, mandragora, +7 more Probable
What it is: European mandrake is a highly toxic plant from the nightshade family that was used in ancient and medieval times as a sedative and pain reli...
Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European mandrake.
Read the full European Mandrake + Brincidofovir interactionGlucomannanGlucomanano, glucomannane, konjac, +1 more Probable
What it is: Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipati...
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Brincidofovir interactionGreen TeaCamellia Sinensis, green Sencha Tea, green Tea Extract, +17 more Probable
What it is: Green tea is a popular beverage rich in antioxidants called catechins, and drinking it in normal amounts is considered safe for most people.
Theoretically, green tea might reduce the absorption of organic anion-transporting polypeptide (OATP) substrates.
Read the full Green Tea + Brincidofovir interactionBanabaLagerstroemia Speciosa, banaba Extract, banabalean, +8 more Possible
What it is: Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic...
Theoretically, concomitant use of banaba with substrates of OATP might reduce the bioavailability of the OATP substrate.
Read the full Banaba + Brincidofovir interactionBlack Tea Possible
What it is: Black tea is a popular caffeinated drink made from the fully oxidized leaves of the Camellia sinensis plant, and it contains caffeine and an...
Theoretically, black tea might reduce the absorption of organic anion-transporting polypeptide (OATP) substrates.
Read the full Black Tea + Brincidofovir interactionGuar GumDietary Fiber, farine De Guar, fibre Alimentaire, +10 more Possible
What it is: Guar gum is a soluble, gel-forming fiber from the guar bean that may modestly help with cholesterol, blood sugar, and bowel regularity.
Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.
Read the full Guar Gum + Brincidofovir interactionGum ArabicAcacia, acacia Gum, arabic Gum, +16 more Possible
What it is: Gum arabic is a soluble dietary fiber from the acacia tree that is widely used as a safe food additive and is sometimes taken as a supplemen...
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Gum Arabic + Brincidofovir interactionMethoxylated Flavones Possible
What it is: Methoxylated flavones (often called polymethoxyflavones) are a group of plant compounds, found mainly in citrus peel, that include substance...
In vitro, methoxylated flavones inhibit organic anion transporting polypeptide (OATP) 1B1, 1B3, and 2B1.
Read the full Methoxylated Flavones + Brincidofovir interactionQuercetin7-pentahydroxyflavone, bioflavonoid, bioflavonoid Complex, +9 more Possible
What it is: Quercetin is a plant flavonoid with antioxidant and anti-inflammatory properties found in many common foods and sold as a supplement.
Theoretically, concomitant use might increase the effects and adverse effects of OATP substrates.
Read the full Quercetin + Brincidofovir interactionSlippery ElmIndian Elm, moose Elm, olmo Americano, +7 more Possible
What it is: Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and ir...
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Brincidofovir interactionSorrelRumex Acetosa, acedera, azeda-brava, +13 more Possible
What it is: Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation.
Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
Read the full Sorrel + Brincidofovir interactionTheaflavin Possible
What it is: Theaflavins are antioxidant compounds formed when tea leaves are oxidized to make black tea.
In vitro, theaflavin inhibits organic anion-transporting polypeptide (OATP)2B1.
Read the full Theaflavin + Brincidofovir interactionTragacanthAdragante, astragale Adragant, astragale De Marseille, +14 more Possible
What it is: Tragacanth is a plant gum used mainly as a thickener and emulsifier in foods, cosmetics, and medicines, and traditionally to soothe the thro...
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Tragacanth + Brincidofovir interactionTurmericCurcuma Longa, curcuma, curcumae Longa, +17 more Possible
What it is: Turmeric is a popular spice whose main active compounds, curcuminoids, are studied mostly for inflammation and joint pain.
Theoretically, turmeric might increase blood levels of OATP4C1 substrates.
Read the full Turmeric + Brincidofovir interactionThyroid Extract Likely
What it is: Thyroid extract supplements are made from dried animal thyroid gland and may contain real thyroid hormones (T3 and T4), but the amounts in o...
Food and medications can interfere with thyroid hormone absorption.
Read the full Thyroid Extract + Brincidofovir interactionAgarAgar-agar, agarose, agarose Gel, +17 more Possible
What it is: Agar is a plant-based gel made from red seaweed that is widely used as a vegetarian alternative to gelatin and as a source of dietary fiber.
Agar forms a thick gel, which may disrupt the absorption of nutrients and medications.
Read the full Agar + Brincidofovir interactionAlginAlginate, alginate De Calcium, alginate De Magnésium, +12 more Possible
What it is: Algin (alginate) is a fiber-like substance from brown seaweed that is widely used as a thickener, gel, and binder in foods and medicines.
Theoretically, algin can alter the absorption of oral drugs.
Read the full Algin + Brincidofovir interactionBaikal SkullcapScutellaria Baicalensis, baikal Scullcap, baikal Skullcap Root, +16 more Possible
What it is: Baikal skullcap is a traditional Chinese herb (Huang Qin) used for inflammation, allergies, and infections, with active compounds like baica...
Theoretically, Baikal skullcap might alter the levels and clinical effects of OATP substrates.
Read the full Baikal Skullcap + Brincidofovir interactionBlack CohoshActaea Racemosa, baie D'actée, baneberry, +10 more Possible
What it is: Black cohosh is a North American plant most often used to ease menopause symptoms like hot flashes, but the research is mixed and far from s...
Black cohosh may inhibit one form of OATP, OATP2B1, which could reduce the bioavailability and clinical effects of OATP2B1 substrates.
Read the full Black Cohosh + Brincidofovir interactionBlack PsylliumAfrican Plantain, brown Psyllium, dietary Fiber, +16 more Possible
What it is: Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive...
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Black Psyllium + Brincidofovir interactionBlond PsylliumPlantago Ovata, balle De Psyllium, blond Plantago, +14 more Possible
What it is: Blond psyllium is a soluble fiber from the seed husks of Plantago ovata, and it is one of the better-studied fiber supplements.
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Blond Psyllium + Brincidofovir interactionCarobCeratonia Siliqua, algarrobo, carob Flour, +16 more Possible
What it is: Carob is a Mediterranean tree whose pods are widely used as a caffeine-free, naturally sweet cocoa alternative and as a thickener (carob gum...
Theoretically, carob might also impair the absorption of oral drugs.
Read the full Carob + Brincidofovir interactionEleutheroEleutherococcus Senticosus, acanthopanax Obovatus, ciwujia Root, +13 more Possible
What it is: Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress.
Theoretically, eleuthero might decrease levels of drugs metabolized by OATP.
Read the full Eleuthero + Brincidofovir interactionKaraya GumBassora Tragacanth, goma Karaya, gomme Karaya, +14 more Possible
What it is: Karaya gum is a natural plant gum from the Sterculia tree that is mostly used as a bulk-forming laxative and as a thickener or adhesive in f...
Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption of drugs.
Read the full Karaya Gum + Brincidofovir interactionMarshmallowAlthaea Officinalis, altea, alteia, +16 more Possible
What it is: Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sor...
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow + Brincidofovir interactionMilk ThistleSilybum Marianum, artichaut Sauvage, blessed Milk Thistle, +12 more Possible
What it is: Milk thistle is a popular herbal supplement most often used for liver health, and its main active component is a group of compounds called s...
Milk thistle may inhibit one form of OATP, OATP-B1, which could reduce the bioavailability and clinical effects of OATP-B1 substrates.
Read the full Milk Thistle + Brincidofovir interactionPassion FlowerPassiflora Incarnata, apricot Vine, burucuya, +18 more Possible
What it is: Passion flower is a traditional calming herb that many people use for anxiety and sleep.
Theoretically, passion flower might reduce the bioavailability of OATP2B1 and OATP1A2 substrates.
Read the full Passion Flower + Brincidofovir interactionPuravive Possible
What it is: Puravive is a branded, multi-ingredient capsule marketed mainly for weight loss by claiming to boost brown fat activity, but there is no pub...
Puravive contains quercetin.
Read the full Puravive + Brincidofovir interactionXanthan GumBacterial Polysaccharide, corn Sugar Gum, goma Xantana, +7 more Possible
What it is: Xanthan gum is a fermentation-made fiber widely used to thicken and stabilize foods and to thicken liquids for people with swallowing diffic...
Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities.
Read the full Xanthan Gum + Brincidofovir interactionCan You Take It With Brincidofovir?
One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.
Can you take Apple with Brincidofovir?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Concomitant consumption of apple juice can significantly decrease oral absorption and blood levels of OATP substrates.
Full Apple + Brincidofovir answerCan you take Xanthan Gum with Brincidofovir?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities.
Full Xanthan Gum + Brincidofovir answerCan you take Grapefruit with Brincidofovir?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Grapefruit juice can decrease levels of drugs that are substrates of OATP.
Full Grapefruit + Brincidofovir answerCan you take Sweet Orange with Brincidofovir?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Consuming sweet orange juice can decrease oral absorption of OATP substrates.
Full Sweet Orange + Brincidofovir answerCan you take Activated Charcoal with Brincidofovir?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the rout...
Full Activated Charcoal + Brincidofovir answerCan you take Coffee Charcoal with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two...
Full Coffee Charcoal + Brincidofovir answerCan you take European Mandrake with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European...
Full European Mandrake + Brincidofovir answerCan you take Glucomannan with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, glucomannan may decrease absorption of drugs taken orally.
Full Glucomannan + Brincidofovir answerCan you take Green Tea with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, green tea might reduce the absorption of organic anion-transporting polypeptide (OATP) substrates.
Full Green Tea + Brincidofovir answerCan you take Banaba with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of banaba with substrates of OATP might reduce the bioavailability of the OATP substrate.
Full Banaba + Brincidofovir answerCan you take Black Tea with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, black tea might reduce the absorption of organic anion-transporting polypeptide (OATP) substrates.
Full Black Tea + Brincidofovir answerCan you take Guar Gum with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.
Full Guar Gum + Brincidofovir answerCan you take Gum Arabic with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Full Gum Arabic + Brincidofovir answerCan you take Methoxylated Flavones with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, methoxylated flavones inhibit organic anion transporting polypeptide (OATP) 1B1, 1B3, and 2B1.
Full Methoxylated Flavones + Brincidofovir answerCan you take Quercetin with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the effects and adverse effects of OATP substrates.
Full Quercetin + Brincidofovir answerCan you take Slippery Elm with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Full Slippery Elm + Brincidofovir answerCan you take Sorrel with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
Full Sorrel + Brincidofovir answerCan you take Theaflavin with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, theaflavin inhibits organic anion-transporting polypeptide (OATP)2B1.
Full Theaflavin + Brincidofovir answerCan you take Tragacanth with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tragacanth might alter absorption of oral drugs.
Full Tragacanth + Brincidofovir answerCan you take Turmeric with Brincidofovir?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, turmeric might increase blood levels of OATP4C1 substrates.
Full Turmeric + Brincidofovir answerWhat Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
How Does Our Interaction Checker Work?
Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).
So the check works in three steps: (1) Brincidofovir is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Brincidofovir, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.
Brincidofovir sits in 2 interaction categories. Open any one to see what the group means:
Oral Drugs 17 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
17 of the supplement ingredients on this page reach Brincidofovir through this category.
Organic Anion-Transporting Polypeptide Substrates (Oatp) 17 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
17 of the supplement ingredients on this page reach Brincidofovir through this category.
Take a Supplement Product? Check the Whole Bottle Against Brincidofovir
Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Brincidofovir.
Search a supplement product
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Products that contain Brincidofovir-interacting ingredients
Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Brincidofovir.
Brincidofovir & Supplements: Common Questions
What supplements interact with Brincidofovir?
Which Brincidofovir supplement interactions are the most serious?
Can I take vitamins or supplements while on Brincidofovir?
Do brands like Tembexa have the same supplement interactions as Brincidofovir?
Where do these interaction ratings come from?
What about Brincidofovir and my other medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Where This Data Comes From — and Why You Can Trust It
🧪 Licensed clinical database
Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.
🧑⚕️ Pharmacist review
This page is curated and coded by Dr. Brian Staiger, PharmD, BCPS, Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.
🔄 Kept current
Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 15, 2026.
🔍 Full transparency
How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.
Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.