Medication interaction hub

What Supplements Interact with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Chlorpheniramine Maleate, Hydrocodone Bitartrate brand name: Vituz. Every interaction below applies to the brands too.

258 Interactions 12 Major 204 Moderate 42 Minor
Curated & coded by · Clinical Pharmacist · Updated September 18, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Chlorpheniramine Maleate, Hydrocodone Bitartrate? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Chlorpheniramine Maleate, Hydrocodone Bitartrate against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line

258 supplements and herbal ingredients have interactions with Chlorpheniramine Maleate, Hydrocodone Bitartrate on file in the HelloPharmacist interaction database — 12 rated major, 204 moderate, and 42 minor. The most serious involve Beer, Grapefruit, Wine, 1,4-butanediol and Activated Charcoal.

Our assessment: with 12 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Chlorpheniramine Maleate, Hydrocodone Bitartrate.

Major 12 Moderate 204 Minor 42 No known interaction 1,194

Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Chlorpheniramine Maleate, Hydrocodone Bitartrate: Top Interactions at a Glance

The Chlorpheniramine Maleate, Hydrocodone Bitartrate supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 258 interacting ingredients — plus 1,194 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Chlorpheniramine Maleate, Hydrocodone Bitartrate Combinations Today

The Chlorpheniramine Maleate, Hydrocodone Bitartrate + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Moringa + Chlorpheniramine Maleate, Hydrocodone Bitartratei

Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.

Read the full interaction Moderate Likelihood Possible Bitter Orange + Chlorpheniramine Maleate, Hydrocodone Bitartratei

Bitter orange might increase levels of drugs metabolized by CYP3A4.

Read the full interaction Moderate Likelihood Possible Cranberry + Chlorpheniramine Maleate, Hydrocodone Bitartratei

Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.

Read the full interaction Moderate Likelihood Possible Ashwagandha + Chlorpheniramine Maleate, Hydrocodone Bitartratei

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.

Read the full interaction Minor Likelihood Possible Marshmallow + Chlorpheniramine Maleate, Hydrocodone Bitartratei

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.

Read the full interaction Moderate Likelihood Possible Padang Cassia + Chlorpheniramine Maleate, Hydrocodone Bitartratei

In vitro research shows that a methanol extract of Padang cassia inhibits cytochrome P450 3A4 (CYP3A4) activity.

Read the full interaction
The complete list

Every Supplement Checked Against Chlorpheniramine Maleate, Hydrocodone Bitartrate

All 1,452 ingredients in our database, ranked by severity — 258 with a Chlorpheniramine Maleate, Hydrocodone Bitartrate interaction on file and 1,194 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Chlorpheniramine Maleate, Hydrocodone Bitartrate?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Moringa with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.

Full Moringa + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Bitter Orange with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bitter orange might increase levels of drugs metabolized by CYP3A4.

Full Bitter Orange + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Cranberry with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.

Full Cranberry + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Ashwagandha with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.

Full Ashwagandha + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Marshmallow with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, mucilage in marshmallow might impair absorption of oral drugs.

Full Marshmallow + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Fo-ti with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, fo-ti may increase the levels and clinical effects of drugs metabolized by CYP2D6.

Full Fo-ti + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Galphimia Glauca with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Galphimia glauca with CNS depressants may increase the risk of sedation.

Full Galphimia Glauca + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Gamma Butyrolactone (gbl) with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of GBL with CNS depressants may potentiate respiratory and CNS depression.

Full Gamma Butyrolactone (gbl) + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Garcinia with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin sy...

Full Garcinia + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Garlic with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.

Full Garlic + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take German Chamomile with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, German chamomile might have additive effects when used with CNS depressants.

Full German Chamomile + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Ginger with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Ginger might increase or decrease the levels of CYP3A4 substrates.

Full Ginger + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Ginkgo with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking ginkgo with drugs that lower the seizure threshold might increase the risk for convulsions.

Full Ginkgo + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Goji with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, goji berry might inhibit CYP2D6 and reduce metabolism of CYP2D6 substrates.

Full Goji + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Goldthread with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There's very preliminary evidence that berberine, a constituent of goldthread, might inhibit cytochrome P450 3A4 (CYP3A4) enzyme.

Full Goldthread + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Gotu Kola with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.

Full Gotu Kola + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Grape with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.

Full Grape + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Greater Celandine with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Research in vitro shows that chelidonine, a constituent of greater celandine, inhibits cytochrome P450 2D6 (CYP2D6) enzyme activity.

Full Greater Celandine + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Griffonia Simplicifolia with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Griffonia simplicifolia seed extract with CNS depressants might increase the risk of additive CNS depression.

Full Griffonia Simplicifolia + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer

Can you take Guar Gum with Chlorpheniramine Maleate, Hydrocodone Bitartrate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.

Full Guar Gum + Chlorpheniramine Maleate, Hydrocodone Bitartrate answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Chlorpheniramine Maleate, Hydrocodone Bitartrate is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Chlorpheniramine Maleate, Hydrocodone Bitartrate, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Chlorpheniramine Maleate, Hydrocodone Bitartrate sits in 11 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Cns Depressants 78 ingredients

Central-nervous-system depressants. Sedating supplements can intensify drowsiness and slowed reactions when combined.

78 of the supplement ingredients on this page reach Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Cytochrome P450 2D6 (Cyp2D6) Substrates 60 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

60 of the supplement ingredients on this page reach Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Anticholinergic Drugs 30 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

30 of the supplement ingredients on this page reach Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Serotonergic Drugs 20 ingredients

Medications that raise serotonin activity. Combining them with serotonin-active supplements can, in rare cases, push serotonin too high.

20 of the supplement ingredients on this page reach Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Narcotic Drugs 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Cytochrome P450 2D6 (Cyp2D6) Inhibitors 3 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

3 of the supplement ingredients on this page reach Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Serotonergic Drugs 1 ingredient

Medications that raise serotonin activity. Combining them with serotonin-active supplements can, in rare cases, push serotonin too high.

1 of the supplement ingredient on this page reaches Chlorpheniramine Maleate, Hydrocodone Bitartrate through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Chlorpheniramine Maleate, Hydrocodone Bitartrate

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Chlorpheniramine Maleate, Hydrocodone Bitartrate.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

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Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Products that contain Chlorpheniramine Maleate, Hydrocodone Bitartrate-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Chlorpheniramine Maleate, Hydrocodone Bitartrate.

Yeast-Cleanse by Solaray contains Grapefruit Ultimate GCB by M3 Supplement Company contains Grapefruit Neuro Health by Nature’s Craft contains Grapefruit NDF Happy Peach by Bioray Kids contains Grapefruit
Pharmacist Counseling Corner

Chlorpheniramine Maleate, Hydrocodone Bitartrate & Supplements: Common Questions

What supplements interact with Chlorpheniramine Maleate, Hydrocodone Bitartrate?
Our database currently documents 258 ingredients with a known Chlorpheniramine Maleate, Hydrocodone Bitartrate interaction (12 major, 204 moderate, 42 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 258. The highest-ranked right now: Beer, Grapefruit, Wine.
Which Chlorpheniramine Maleate, Hydrocodone Bitartrate supplement interactions are the most serious?
Focus on the major group: Beer, Grapefruit, Wine, 1,4-butanediol and Activated Charcoal, among others. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Chlorpheniramine Maleate, Hydrocodone Bitartrate?
Plenty of supplements coexist fine with Chlorpheniramine Maleate, Hydrocodone Bitartrate; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Vituz have the same supplement interactions as Chlorpheniramine Maleate, Hydrocodone Bitartrate?
Yes — Vituz all contain Chlorpheniramine Maleate, Hydrocodone Bitartrate, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Chlorpheniramine Maleate, Hydrocodone Bitartrate and my other medications?
This page covers Chlorpheniramine Maleate, Hydrocodone Bitartrate against supplements and herbal ingredients. Checking Chlorpheniramine Maleate, Hydrocodone Bitartrate against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 18, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.