Medication interaction hub

What Supplements Interact with Dicloxacillin Injection?

Dicloxacillin Injection brand name: Dynapen Injection. Every interaction below applies to the brands too.

39 Interactions 2 Major 35 Moderate 2 Minor
Curated & coded by · Clinical Pharmacist · Updated September 15, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Dicloxacillin Injection? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Dicloxacillin Injection against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Dicloxacillin Injection (Dynapen) is a penicillin antibiotic used against serious bacterial infections, and this list earns real caution, chiefly for its two major-rated entries. Siberian cocklebur and asarabacca can each damage the kidneys, and pairing them with other kidney-stressing substances risks compounding that harm, so I would avoid both outright. The other 37 entries, 35 moderate and 2 minor, are a milder story, and most are probiotics.

Twenty-seven of the 39 ingredients are probiotic strains or fermented milk, and there the interaction runs backward, since the antibiotic kills the live organisms and the supplement loses its benefit, not the drug. Taking them well apart from your antibiotic doses protects that benefit. Four other ingredients carry the same kidney concern as the majors at a moderate level, and six may lower the seizure threshold, meaning a seizure becomes slightly more likely during treatment.

— , Clinical Pharmacist · July 18, 2026

Major 2 Moderate 35 Minor 2 No known interaction 1,413

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Dicloxacillin Injection: Top Interactions at a Glance

The most significant Dicloxacillin Injection supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 39 interacting ingredients — plus 1,413 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Dicloxacillin Injection + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Likely Siberian Cocklebur + Dicloxacillin Injectioni

Siberian cocklebur can adversely affect the kidney.

Read the full interaction Major Likelihood Possible Asarabacca + Dicloxacillin Injectioni

Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.

Read the full interaction
The complete list

Every Supplement Checked Against Dicloxacillin Injection

All 1,452 ingredients in our database, ranked by severity — 39 with a Dicloxacillin Injection interaction on file and 1,413 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Dicloxacillin Injection?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Asarabacca with Dicloxacillin Injection?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.

Full Asarabacca + Dicloxacillin Injection answer

Can you take Siberian Cocklebur with Dicloxacillin Injection?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Siberian cocklebur can adversely affect the kidney.

Full Siberian Cocklebur + Dicloxacillin Injection answer

Can you take Bacillus Subtilis with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.

Full Bacillus Subtilis + Dicloxacillin Injection answer

Can you take Bifidobacterium Animalis Subsp. Lactis with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Bifidobacterium lactis with antibiotic drugs might decrease the effectiveness of B.

Full Bifidobacterium Animalis Subsp. Lactis + Dicloxacillin Injection answer

Can you take Bifidobacterium Bifidum with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Bifidobacterium.

Full Bifidobacterium Bifidum + Dicloxacillin Injection answer

Can you take Bifidobacterium Breve with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.

Full Bifidobacterium Breve + Dicloxacillin Injection answer

Can you take Bifidobacterium Longum with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.

Full Bifidobacterium Longum + Dicloxacillin Injection answer

Can you take Fermented Milk with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, antibiotic drugs might decrease the effectiveness of fermented milk.

Full Fermented Milk + Dicloxacillin Injection answer

Can you take Lacticaseibacillus Casei with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lacticaseibacillus casei with antibiotic drugs might decrease the effectiveness of L.

Full Lacticaseibacillus Casei + Dicloxacillin Injection answer

Can you take Lacticaseibacillus Paracasei with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lacticaseibacillus paracasei with antibiotic drugs might decrease the effectiveness of L.

Full Lacticaseibacillus Paracasei + Dicloxacillin Injection answer

Can you take Lacticaseibacillus Rhamnosus with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lacticaseibacillus rhamnosus with antibiotic drugs might decrease the effectiveness of L.

Full Lacticaseibacillus Rhamnosus + Dicloxacillin Injection answer

Can you take Lactiplantibacillus Pentosus with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lactiplantibacillus pentosus with antibiotic drugs might decrease the effectiveness of L.

Full Lactiplantibacillus Pentosus + Dicloxacillin Injection answer

Can you take Lactiplantibacillus Plantarum with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lactiplantibacillus plantarum with antibiotic drugs might decrease the effectiveness of L.

Full Lactiplantibacillus Plantarum + Dicloxacillin Injection answer

Can you take Lactobacillus Acidophilus with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.

Full Lactobacillus Acidophilus + Dicloxacillin Injection answer

Can you take Lactobacillus Crispatus with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lactobacillus crispatus with antibiotic drugs might decrease the effectiveness of L.

Full Lactobacillus Crispatus + Dicloxacillin Injection answer

Can you take Lactobacillus Delbrueckii with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.

Full Lactobacillus Delbrueckii + Dicloxacillin Injection answer

Can you take Lactobacillus Gasseri with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L.

Full Lactobacillus Gasseri + Dicloxacillin Injection answer

Can you take Lactobacillus Helveticus with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L.

Full Lactobacillus Helveticus + Dicloxacillin Injection answer

Can you take Lactobacillus Jensenii with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lactobacillus jensenii with antibiotic drugs might decrease the effectiveness of L.

Full Lactobacillus Jensenii + Dicloxacillin Injection answer

Can you take Lactobacillus Johnsonii with Dicloxacillin Injection?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Lactobacillus johnsonii with antibiotic drugs might decrease the effectiveness of L.

Full Lactobacillus Johnsonii + Dicloxacillin Injection answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Dicloxacillin Injection is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Dicloxacillin Injection, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Dicloxacillin Injection sits in 3 interaction categories. Open any one to see what the group means:

Antibiotic Drugs 27 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

27 of the supplement ingredients on this page reach Dicloxacillin Injection through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Dicloxacillin Injection through this category.

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Dicloxacillin Injection through this category.

Related: does Dicloxacillin Injection deplete any nutrients?

Dicloxacillin Injection has 7 reported nutrient associations in the research literature — see the Dicloxacillin Injection nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Dicloxacillin Injection

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Dicloxacillin Injection.

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Pharmacist Counseling Corner

Dicloxacillin Injection & Supplements: Common Questions

What supplements interact with Dicloxacillin Injection?
In our interaction database, 39 supplement and herbal ingredients have an interaction with Dicloxacillin Injection on file — 2 rated major, 35 moderate, and 2 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Siberian Cocklebur, Asarabacca, Bacillus Coagulans.
Which Dicloxacillin Injection supplement interactions are the most serious?
The 2 major-rated combinations — led by Siberian Cocklebur and Asarabacca — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Dicloxacillin Injection?
That depends entirely on which supplement. The honest answer for Dicloxacillin Injection is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Dynapen Injection have the same supplement interactions as Dicloxacillin Injection?
Yes — Dynapen Injection all contain Dicloxacillin Injection, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Dicloxacillin Injection deplete any vitamins or nutrients?
It might — Dicloxacillin Injection has 7 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Dicloxacillin Injection nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Dicloxacillin Injection and my other medications?
This page covers Dicloxacillin Injection against supplements and herbal ingredients. Checking Dicloxacillin Injection against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 15, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.