Medication interaction hub

What Supplements Interact with Edrophonium, Atropine?

Edrophonium, Atropine brand name: Enlon-Plus. Every interaction below applies to the brands too.

34 Interactions 2 Major 29 Moderate 3 Minor
Curated & coded by · Clinical Pharmacist · Updated September 23, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Edrophonium, Atropine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Edrophonium, Atropine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Enlon-Plus combines edrophonium, which raises levels of the nerve messenger acetylcholine, with atropine, which tempers its side effects, and the supplements listed below can tip that balance in either direction. I read this list with real caution. The two major-rated entries, henbane and scopolia, contain the same tropane alkaloids as atropine itself and can stack its effects, dry mouth, racing heart, blurred vision, and confusion included. Of the 34 ingredients on file, 29 rate moderate and 3 minor.

Most others fall into two camps. Roughly thirty behave like extra atropine and add to that same load, while about twenty mimic edrophonium by blocking the enzyme that clears acetylcholine, which can intensify one half of the drug and undercut the other. Since Enlon-Plus is given by a medical team, usually during anesthesia to reverse muscle relaxants, the most useful step is naming every herb you take before that day.

— , Clinical Pharmacist · July 18, 2026

Major 2 Moderate 29 Minor 3 No known interaction 1,418

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Edrophonium, Atropine: Top Interactions at a Glance

The most significant Edrophonium, Atropine supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 34 interacting ingredients — plus 1,418 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Edrophonium, Atropine + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Probable Henbane + Edrophonium, Atropinei

Concomitant use of henbane can have additive anticholinergic effects and adverse effects with amantadine, antihistamines, atropine, belladonna alkaloids, hyoscy...

Read the full interaction Major Likelihood Probable Scopolia + Edrophonium, Atropinei

The alkaloid constituents of scopolia, including hyoscyamine, scopolamine, and atropine, could potentiate the effects and adverse effects of anticholinergic dru...

Read the full interaction
The complete list

Every Supplement Checked Against Edrophonium, Atropine

All 1,452 ingredients in our database, ranked by severity — 34 with a Edrophonium, Atropine interaction on file and 1,418 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Edrophonium, Atropine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Choline with Edrophonium, Atropine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, choline might decrease the effects of atropine in the brain.

Full Choline + Edrophonium, Atropine answer

Can you take Phosphatidylserine with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.

Full Phosphatidylserine + Edrophonium, Atropine answer

Can you take Belladonna with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Belladonna may increase the risk of adverse effects when used concomitantly with anticholinergic drugs.

Full Belladonna + Edrophonium, Atropine answer

Can you take Betel Nut with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro and animal research suggests that betel nut extract can inhibit acetylcholinesterase activity.

Full Betel Nut + Edrophonium, Atropine answer

Can you take Datura Wrightii with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Datura wrightii contains atropine and scopolamine, as well as other tropane alkaloids with anticholinergic activity.

Full Datura Wrightii + Edrophonium, Atropine answer

Can you take Angel's Trumpet with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use may increase anticholinergic effects and adverse effects.

Full Angel's Trumpet + Edrophonium, Atropine answer

Can you take Arenaria Rubra with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Arenaria rubra, by inhibiting acetylcholinesterase, may theoretically interact with other acetylcholinesterase inhibitors like donepezil and...

Full Arenaria Rubra + Edrophonium, Atropine answer

Can you take Bacopa with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might decrease the effectiveness of both agents.

Full Bacopa + Edrophonium, Atropine answer

Can you take Bael with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bael leaf extract shows acetylcholinesterase (AChE) inhibitory activity in vitro.

Full Bael + Edrophonium, Atropine answer

Can you take Boxwood with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that boxwood extract can inhibit acetylcholinesterase activity.

Full Boxwood + Edrophonium, Atropine answer

Can you take Calamus with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of anticholinergic drugs and calamus might decrease the effectiveness of the anticholinergic drug.

Full Calamus + Edrophonium, Atropine answer

Can you take Clubmoss with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that clubmoss extract can inhibit acetylcholinesterase activity.

Full Clubmoss + Edrophonium, Atropine answer

Can you take Corkwood Tree with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, corkwood tree might increase the risk of adverse anticholinergic effects when taken with anticholinergic drugs.

Full Corkwood Tree + Edrophonium, Atropine answer

Can you take Dimethylsulfoxide (dmso) with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, DMSO might increase the risk of cholinergic adverse effects when taken with cholinergic drugs.

Full Dimethylsulfoxide (dmso) + Edrophonium, Atropine answer

Can you take European Barberry with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.

Full European Barberry + Edrophonium, Atropine answer

Can you take European Mandrake with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concurrent use may cause additive anticholinergic effects and adverse effects.

Full European Mandrake + Edrophonium, Atropine answer

Can you take Huperzine A with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, huperzine A might decrease the effects of anticholinergic drugs.

Full Huperzine A + Edrophonium, Atropine answer

Can you take Iboga with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, iboga might decrease the effectiveness of anticholinergic drugs.

Full Iboga + Edrophonium, Atropine answer

Can you take Jimson Weed with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, jimson weed may increase anticholinergic effects and adverse effects.

Full Jimson Weed + Edrophonium, Atropine answer

Can you take Marjoram with Edrophonium, Atropine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that marjoram extract can inhibit acetylcholinesterase activity.

Full Marjoram + Edrophonium, Atropine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Edrophonium, Atropine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Edrophonium, Atropine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Edrophonium, Atropine sits in 4 interaction categories. Open any one to see what the group means:

Anticholinergic Drugs 30 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

30 of the supplement ingredients on this page reach Edrophonium, Atropine through this category.

Cholinergic Drugs 21 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

21 of the supplement ingredients on this page reach Edrophonium, Atropine through this category.

Acetylcholinesterase (Ache) Inhibitors 2 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

2 of the supplement ingredients on this page reach Edrophonium, Atropine through this category.

Atropine 1 ingredient

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

1 of the supplement ingredient on this page reaches Edrophonium, Atropine through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Edrophonium, Atropine

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Edrophonium, Atropine.

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Products that contain Edrophonium, Atropine-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Edrophonium, Atropine.

Calmhills by Herbal Hills contains Henbane Migrahills by Herbal Hills contains Henbane Migrahills by Herbal Hills contains Henbane Migrahills by Herbal Hills contains Henbane Angiplex by UNDA Plex contains Belladonna Back & Neck Pain by BIOVEA Homeopathics contains Belladonna SuperFlex-H by NewtonEverett contains Belladonna CBD+13 by T-Relief contains Belladonna
Pharmacist Counseling Corner

Edrophonium, Atropine & Supplements: Common Questions

What supplements interact with Edrophonium, Atropine?
Our database currently documents 34 ingredients with a known Edrophonium, Atropine interaction (2 major, 29 moderate, 3 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 34. The highest-ranked right now: Henbane, Scopolia, Belladonna.
Which Edrophonium, Atropine supplement interactions are the most serious?
Focus on the major group: Henbane and Scopolia. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Edrophonium, Atropine?
Plenty of supplements coexist fine with Edrophonium, Atropine; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Enlon-Plus have the same supplement interactions as Edrophonium, Atropine?
Yes — Enlon-Plus all contain Edrophonium, Atropine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Edrophonium, Atropine and my other medications?
This page covers Edrophonium, Atropine against supplements and herbal ingredients. Checking Edrophonium, Atropine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 23, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.