Medication interaction hub

What Supplements Interact with Galantamine?

Galantamine brand names: Reminyl, Razadyne. Every interaction below applies to the brands too.

170 Interactions 3 Major 126 Moderate 41 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Galantamine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Galantamine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Galantamine (Razadyne) treats Alzheimer's disease, so it is often a caregiver filling the pill organizer alongside memory supplements and morning juice. That pairing deserves genuine care, because three of the 170 supplement ingredients on file are rated major and two of them are everyday items. Grapefruit can push galantamine's blood level up by blocking the liver enzyme that clears it, while St. John's wort revs that same enzyme and can weaken the drug's effect. Most of the 126 moderate entries pull on those same enzyme pathways in one direction or the other.

Activated charcoal, the third major, can soak up a dose in the gut before it is absorbed, and about 17 entries interfere with oral absorption more broadly, so those belong well apart from the dose, with the full report guiding specifics. A smaller cluster, betel nut among them, adds to galantamine's own cholinergic action, which can stack nausea, cramping, or a slowed heartbeat on top. The 41 minor entries can wait; know the three majors cold.

— , Clinical Pharmacist · July 18, 2026

Major 3 Moderate 126 Minor 41 No known interaction 1,282

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Galantamine: Top Interactions at a Glance

The Galantamine supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 170 interacting ingredients — plus 1,282 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Galantamine Combinations Today

The Galantamine + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Minor Likelihood Unlikely Milk Thistle + Galantaminei

It is unclear if milk thistle inhibits CYP3A4; research is conflicting.

Read the full interaction Moderate Likelihood Possible Marjoram + Galantaminei

In vitro research suggests that marjoram extract can inhibit acetylcholinesterase activity.

Read the full interaction Moderate Likelihood Possible Dimethylsulfoxide (dmso) + Galantaminei

Theoretically, DMSO might increase the risk of cholinergic adverse effects when taken with cholinergic drugs.

Read the full interaction Moderate Likelihood Possible Pomegranate + Galantaminei

Theoretically, pomegranate might increase levels of drugs metabolized by CYP2D6.

Read the full interaction Moderate Likelihood Probable Glucomannan + Galantaminei

Theoretically, glucomannan may decrease absorption of drugs taken orally.

Read the full interaction Moderate Likelihood Possible Bael + Galantaminei

Bael leaf extract shows acetylcholinesterase (AChE) inhibitory activity in vitro.

Read the full interaction
The complete list

Every Supplement Checked Against Galantamine

All 1,452 ingredients in our database, ranked by severity — 170 with a Galantamine interaction on file and 1,282 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Galantamine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Milk Thistle with Galantamine?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. It is unclear if milk thistle inhibits CYP3A4; research is conflicting.

Full Milk Thistle + Galantamine answer

Can you take Marjoram with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that marjoram extract can inhibit acetylcholinesterase activity.

Full Marjoram + Galantamine answer

Can you take Dimethylsulfoxide (dmso) with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, DMSO might increase the risk of cholinergic adverse effects when taken with cholinergic drugs.

Full Dimethylsulfoxide (dmso) + Galantamine answer

Can you take Pomegranate with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, pomegranate might increase levels of drugs metabolized by CYP2D6.

Full Pomegranate + Galantamine answer

Can you take Glucomannan with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, glucomannan may decrease absorption of drugs taken orally.

Full Glucomannan + Galantamine answer

Can you take Grapefruit with Galantamine?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Grapefruit juice can increase levels of drugs metabolized by CYP3A4.

Full Grapefruit + Galantamine answer

Can you take Activated Charcoal with Galantamine?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the rout...

Full Activated Charcoal + Galantamine answer

Can you take St. John's Wort with Galantamine?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. St.

Full St. John's Wort + Galantamine answer

Can you take Ayahuasca with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, ayahuasca might increase plasma concentrations of CYP2D6 substrates.

Full Ayahuasca + Galantamine answer

Can you take Betel Nut with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro and animal research suggests that betel nut extract can inhibit acetylcholinesterase activity.

Full Betel Nut + Galantamine answer

Can you take Cannabidiol (cbd) with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Cannabidiol may increase levels of drugs that are metabolized by CYP3A4.

Full Cannabidiol (cbd) + Galantamine answer

Can you take Coffee Charcoal with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two...

Full Coffee Charcoal + Galantamine answer

Can you take European Mandrake with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European...

Full European Mandrake + Galantamine answer

Can you take Goldenseal with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Goldenseal might increase serum levels of drugs metabolized by CYP2D6.

Full Goldenseal + Galantamine answer

Can you take Guggul with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, guggul might reduce the effects of CYP3A4 substrates.

Full Guggul + Galantamine answer

Can you take Schisandra with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Schisandra can increase the levels and clinical effects of drugs metabolized by CYP3A4.

Full Schisandra + Galantamine answer

Can you take Syrian Rue with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Syrian rue might increase the levels and clinical effects of drugs metabolized by CYP2D6.

Full Syrian Rue + Galantamine answer

Can you take Tree Turmeric with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tree turmeric might increase the levels and clinical effects of drugs that are substrates of CYP3A4.

Full Tree Turmeric + Galantamine answer

Can you take 1,3-dmaa with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. 1,3-DMAA strongly inhibits cytochrome P450 2D6 (CYP2D6) enzymes in vitro.

Full 1,3-dmaa + Galantamine answer

Can you take Acacia Rigidula with Galantamine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Acacia rigidula products that are adulterated with beta-methylphenylethylamine (BMPEA) might increase the levels of CYP2D6 su...

Full Acacia Rigidula + Galantamine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Galantamine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Galantamine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Galantamine sits in 5 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Galantamine through this category.

Cytochrome P450 2D6 (Cyp2D6) Substrates 60 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

60 of the supplement ingredients on this page reach Galantamine through this category.

Cholinergic Drugs 21 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

21 of the supplement ingredients on this page reach Galantamine through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Galantamine through this category.

Acetylcholinesterase (Ache) Inhibitors 2 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

2 of the supplement ingredients on this page reach Galantamine through this category.

About Galantamine

Galantamine is a cholinesterase inhibitor used to treat mild to moderate dementia of the Alzheimer's type.

Generic name: Galantamine  ·  Brand names: Reminyl, Razadyne.

See the full Galantamine drug information
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Pharmacist Counseling Corner

Galantamine & Supplements: Common Questions

What supplements interact with Galantamine?
In our interaction database, 170 supplement and herbal ingredients have an interaction with Galantamine on file — 3 rated major, 126 moderate, and 41 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Grapefruit, Activated Charcoal, St. John's Wort.
Which Galantamine supplement interactions are the most serious?
Focus on the major group: Grapefruit, Activated Charcoal and St. John's Wort. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Galantamine?
That depends entirely on which supplement. The honest answer for Galantamine is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Reminyl have the same supplement interactions as Galantamine?
Yes — Reminyl, Razadyne all contain Galantamine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Galantamine and my other medications?
This page covers Galantamine against supplements and herbal ingredients. Checking Galantamine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Galantamine drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.