Drug & supplement interaction

Proline + Galantamine

Galantamine brand names: Reminyl, Razadyne.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Proline and Galantamine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Galantamine states a food rule worth keeping to.

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Interaction report

Proline and Galantamine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Galantamine and Proline in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Proline at all — not against Galantamine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Proline safety at a glance

Proline overall Use caution Generally considered low-risk from food, but supplement safety has not been well studied.
Pregnancy Use caution Not enough reliable data on supplemental doses, so it is best to avoid extra amounts unless your doctor advises.
Breastfeeding Use caution Safety of supplemental doses while breastfeeding is not established, so use caution.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Galantamine and Proline? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Galantamine’s Own FDA Label Lists

This is not an interaction — none of it involves Proline. These are the most notable effects listed in the ADVERSE REACTIONS section of Galantamine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 4 of them are worth acting on rather than waiting out — marked below.

  • Memory problems Worth acting on mentioned in 20.8% of FDA reports for Galantamine
  • A slow heartbeat Worth acting on
  • Fainting Worth acting on
  • Low mood Worth acting on
  • Drowsiness mentioned in 18.4% of FDA reports for Galantamine
  • Weight loss
  • Tremor or shakiness
  • Reduced appetite
  • Muscle pain
  • Stomach upset

Showing the 10 most notable of 17 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Galantamine. Read the label on DailyMed › Where a percentage is shown, it is the share of 3,188 voluntary FDA FAERS reports for Galantamine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Proline’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Proline side to compare — that is a limit of the record, not a statement that Proline has no side effects.

How to take them

Some Galantamine Products Have a Food Rule — Proline Should Not Break It

At least one FDA label for a product containing Galantamine says to take it with food. If you take Proline on an empty stomach out of habit, keep them separate — and take Galantamine with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Galantamine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2.1 ) Take with food; ensure adequate fluid intake during treatment (2.1) Hepatic impairment: should not exceed 16 mg/day for moderate hepatic impairment; do not use in patients with severe hepatic impairment ( 2.2 ) Renal impairment: should not exceed 16 mg/day for creatinine clearance 9 to 59 mL/min; do not use in patients with creatinine clearance less than 9 mL/min.

From the Dosage and Administration section of the FDA label we read for Galantamine — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Galantamine

This page covers Proline only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Galantamine page lists 170 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), 1,3-dmaa (moderate) and Acacia Rigidula (moderate).

By severity: 3 major · 126 moderate · 41 minor.

From our pharmacist’s overview on the Galantamine page

“Galantamine (Razadyne) treats Alzheimer's disease, so it is often a caregiver filling the pill organizer alongside memory supplements and morning juice. That pairing deserves genuine care, because three of the 170 supplement ingredients on file are rated major and two of them are everyday items.”

Reviewed by 2 · Jul 18, 2026

Open the Galantamine interaction page

One more smart check

Taking Proline as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,054 real supplement products containing Proline, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Proline. Even though Proline itself has no known interaction with Galantamine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Proline and Galantamine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Proline
Top 25%

#217 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Galantamine
Top half

#1,249 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Proline reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Proline and Galantamine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Proline

What is Proline?

  • Joint and connective tissue support
  • Skin health and wound healing
  • Collagen production
  • Athletic recovery
  • General amino acid supplementation

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of collagen, but strong human evidence that taking proline supplements improves skin, joints, or healing is limited. For most healthy people a balanced diet supplies plenty, so talk to your pharmacist or doctor before adding a supplement.

Amino acid (made by the body and found in protein-rich foods) · Capsules, powders, and as part of collagen or amino acid blends

An interaction check asks whether these two react with each other — it does not ask whether Proline is a good idea for someone in your situation. Here is what our Proline record says about it on its own.

Proline: dosing

There is no well-established standard dose of proline as a supplement. Amounts vary widely between products, and proline is often combined with other amino acids or collagen rather than taken alone.If you choose to use a proline-containing product, follow the directions on the label and do not exceed the recommended amount.

From our Proline monograph — the full record covers uses, side effects and every documented interaction.

Read the full Proline monograph & all interactions
Medication

About Galantamine

What Is Galantamine Used For?

Brand names: Reminyl, Razadyne

Galantamine — available as extended-release capsules, tablets, and an oral solution — is used to treat mild to moderate dementia caused by Alzheimer's disease. All supported formulations share this indication.

It does not cure or slow the underlying disease, but it can help support cognitive function in people with early to moderate-stage Alzheimer's. Its benefits may lessen as the disease progresses and more brain cells are lost.

Most-Reported Side Effects for Galantamine

From FAERS, the FDA’s public side-effect reporting system (3,188 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fall 812 reports
Cognitive disorder 664 reports
Constipation 651 reports
Balance disorder 632 reports
Hypotension 631 reports
See full Galantamine drug information
Keep checking

Other Drugs & Proline

Browse every other medication we’ve checked against Proline — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Proline References

The 4 references that drive our Proline monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Proline and Galantamine Together: Common Questions

Is it safe to take Proline with Galantamine?
We do not list a known interaction between Proline and Galantamine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Proline and Galantamine at the same time of day?
At least one FDA label for a product containing Galantamine says to take it with food. If you take Proline on an empty stomach out of habit, keep them separate and take Galantamine with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Galantamine products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Galantamine interact with any supplements?
Yes. Galantamine has documented interactions with 170 supplements in our database — Proline is not one of them. The Galantamine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Galantamine and Proline?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.