Medication interaction hub

What Supplements Interact with Sodium Nitrite, Sodium Thiosulfate?

Sodium Nitrite, Sodium Thiosulfate brand name: Nithiodote. Every interaction below applies to the brands too.

6 Interactions 6 Moderate
Curated & coded by · Clinical Pharmacist · Updated September 25, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Sodium Nitrite, Sodium Thiosulfate? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Sodium Nitrite, Sodium Thiosulfate against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Nithiodote pairs sodium nitrite with sodium thiosulfate to treat cyanide poisoning, an emergency IV drug rather than a pill taken at home. All six entries on this page share one theme, a possible lowering of the seizure threshold, meaning each could theoretically nudge seizure risk upward alongside this treatment. None rises above moderate, all rest on theoretical or animal evidence, and melatonin and ginkgo are the two most people would actually have in the cabinet.

Because cyanide treatment happens in a crisis, the realistic moment for this list is recovery, when someone asks what supplements to restart. Thuja, which contains the neurotoxin thujone, is the one I would keep on hold until the care team clears it. The rest read as combinations worth watching during that window, not forbidden ones.

— , Clinical Pharmacist · July 18, 2026

Moderate 6 No known interaction 1,446

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Sodium Nitrite, Sodium Thiosulfate: Top Interactions at a Glance

The most significant Sodium Nitrite, Sodium Thiosulfate supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 6 highest-ranked of 6 interacting ingredients — plus 1,446 more checked with no known interaction. See the complete ranked list.

Start here

The Moderate Interactions to Know About

The most clinically significant Sodium Nitrite, Sodium Thiosulfate + supplement combinations in our database, best-documented first. Open any card for the full report.

Moderate Likelihood Possible Biofeedback + Sodium Nitrite, Sodium Thiosulfatei

There is some concern that electroencephalogram (EEG) biofeedback might lower the seizure threshold in some patients.

Read the full interaction Moderate Likelihood Possible Dendrobium + Sodium Nitrite, Sodium Thiosulfatei

The dendrobium constituent dendrobine is reported to have convulsant effects.

Read the full interaction Moderate Likelihood Possible Ginkgo + Sodium Nitrite, Sodium Thiosulfatei

Theoretically, taking ginkgo with drugs that lower the seizure threshold might increase the risk for convulsions.

Read the full interaction Moderate Likelihood Possible Melatonin + Sodium Nitrite, Sodium Thiosulfatei

Theoretically, taking melatonin with drugs that lower the seizure threshold might increase the risk of seizure activity.

Read the full interaction Moderate Likelihood Possible Rauwolscine + Sodium Nitrite, Sodium Thiosulfatei

Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.

Read the full interaction Moderate Likelihood Possible Thuja + Sodium Nitrite, Sodium Thiosulfatei

Thuja products can contains significant amounts of thujone, a neurotoxin.

Read the full interaction
The complete list

Every Supplement Checked Against Sodium Nitrite, Sodium Thiosulfate

All 1,452 ingredients in our database, ranked by severity — 6 with a Sodium Nitrite, Sodium Thiosulfate interaction on file and 1,446 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Sodium Nitrite, Sodium Thiosulfate?

One-line answers, one card per combination — scroll through today’s 12 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Biofeedback with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is some concern that electroencephalogram (EEG) biofeedback might lower the seizure threshold in some patients.

Full Biofeedback + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Dendrobium with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. The dendrobium constituent dendrobine is reported to have convulsant effects.

Full Dendrobium + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Ginkgo with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking ginkgo with drugs that lower the seizure threshold might increase the risk for convulsions.

Full Ginkgo + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Melatonin with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking melatonin with drugs that lower the seizure threshold might increase the risk of seizure activity.

Full Melatonin + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Rauwolscine with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.

Full Rauwolscine + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Thuja with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Thuja products can contains significant amounts of thujone, a neurotoxin.

Full Thuja + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Biofeedback with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is some concern that electroencephalogram (EEG) biofeedback might lower the seizure threshold in some patients.

Full Biofeedback + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Dendrobium with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. The dendrobium constituent dendrobine is reported to have convulsant effects.

Full Dendrobium + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Ginkgo with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking ginkgo with drugs that lower the seizure threshold might increase the risk for convulsions.

Full Ginkgo + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Melatonin with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking melatonin with drugs that lower the seizure threshold might increase the risk of seizure activity.

Full Melatonin + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Rauwolscine with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.

Full Rauwolscine + Sodium Nitrite, Sodium Thiosulfate answer

Can you take Thuja with Sodium Nitrite, Sodium Thiosulfate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Thuja products can contains significant amounts of thujone, a neurotoxin.

Full Thuja + Sodium Nitrite, Sodium Thiosulfate answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Sodium Nitrite, Sodium Thiosulfate is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Sodium Nitrite, Sodium Thiosulfate, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Sodium Nitrite, Sodium Thiosulfate sits in 1 interaction category. Open any one to see what the group means:

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Sodium Nitrite, Sodium Thiosulfate through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Sodium Nitrite, Sodium Thiosulfate

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Sodium Nitrite, Sodium Thiosulfate.

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Pharmacist Counseling Corner

Sodium Nitrite, Sodium Thiosulfate & Supplements: Common Questions

What supplements interact with Sodium Nitrite, Sodium Thiosulfate?
More than you might expect — 6 in total, though they are far from equal: 0 are rated major, 6 moderate, and 0 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Biofeedback, Dendrobium, Ginkgo.
Which Sodium Nitrite, Sodium Thiosulfate supplement interactions are the most serious?
None of the Sodium Nitrite, Sodium Thiosulfate supplement interactions on file are currently rated major. The most significant are the 6 moderate-rated ones — combinations that may need monitoring, a dose adjustment, or separated timing. Still worth a quick look through the ranked list for anything you take daily. Jump to the ranked list.
Can I take vitamins or supplements while on Sodium Nitrite, Sodium Thiosulfate?
Usually yes — most people on Sodium Nitrite, Sodium Thiosulfate can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Nithiodote have the same supplement interactions as Sodium Nitrite, Sodium Thiosulfate?
Yes — Nithiodote all contain Sodium Nitrite, Sodium Thiosulfate, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Sodium Nitrite, Sodium Thiosulfate and my other medications?
This page covers Sodium Nitrite, Sodium Thiosulfate against supplements and herbal ingredients. Checking Sodium Nitrite, Sodium Thiosulfate against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 25, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.