100% Organic Spirulina 500 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking 100% Organic Spirulina 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
100% Organic Spirulina 500 mg is a dietary supplement by Vitamer Laboratories with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, antioxidant support, cholesterol and metabolic health.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Spirulina. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against 100% Organic Spirulina 500 mg by Vitamer Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with 100% Organic Spirulina 500 mg by Vitamer Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of 100% Organic Spirulina 500 mg by Vitamer Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains a single active ingredient: organic spirulina, a blue-green algae, at 500 mg per tablet. There are no other inactive ingredients listed.
Does it work?
Moderate evidence
Spirulina has been rated possibly effective for high blood pressure (hypertension) in our data. For acne, hay fever (allergic rhinitis), iron deficiency anemia, and arsenic poisoning, the evidence isn't established — we have insufficient reliable evidence to rate whether it works for these uses.
How safe is it?
Well-documented data
Spirulina is generally well tolerated when taken by mouth. The most common side effects in studies were stomach upset: abdominal cramps, bloating, diarrhea, dizziness, fatigue, gas, headache, nausea, and vomiting.
Allergic reactions including rashes and itching have occurred; one rare case of severe anaphylaxis (a life-threatening allergic reaction) was reported in a teenager. A small number of people taking spirulina reported mild gum bleeding or bruising.
A major caution: quality varies widely between products, and some spirulina supplements can be contaminated with toxins or heavy metals. The safety data available is limited, and contamination risk is a real concern — talk with your pharmacist about whether this product has been third-party tested for purity.
Meds to double-check
Moderate interaction found
Double-check this product if you take blood thinners or antiplatelet drugs (Moderate severity), immunosuppressants (Moderate severity), or diabetes medications (Moderate severity). No interactions are documented beyond these three categories.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Spirulina might help with high blood pressure, but the evidence for other uses isn't clear. If you take blood thinners, immunosuppressants, or diabetes medications, check with your pharmacist first.
Before you buy, ask whether the brand has been tested for heavy metals and toxins.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2016.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about 100% Organic Spirulina 500 mg, straight from the product label.
| Brand | Vitamer Laboratories |
|---|---|
| Barcode (UPC) | 719985141409 |
| Net contents | 100 Vegetarian Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 21, 2016 |
| DSLD ID | 67276 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for 100% Organic Spirulina 500 mg by Vitamer Laboratories, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Our Ultimate Organics products do not contain conventional pesticides, synthetic fertilizers, growth hormones, genetic modification or antibiotics.
We source only natural, organic raw materials that promote the use of renewable resources and conservation and are reviewed by USDA-approved organic certifiers.
Pesticide and Herbicide free
This product is certified organic by Quality Assurance International (QAI).
Contains no artificial colors, flavors or preservatives; no wheat, gluten, milk, eggs, peanuts, tree nuts, soy, crustacean shellfish or fish.
Suitable for vegans.
Our 100% Organic Spirulina is a certified organic whole food concentrate, providing a naturally rich source of vitamins, trace minerals, mixed carotenoids, antioxidants, and essential fatty acids.
Precautions
BMAA (beta-N-methylamino-L-alanine) is a toxin sometimes associated with spirulina.
Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.
Keep out of reach of children.
General Statements
We guarantee our supplements for potency and purity
Green super food
Our tablets are 100% organic without herbicides, pesticides, fertilizers or preservatives and tests negative for BMAA.
Typical Analysis: (Each serving may typically provide the following naturally occurring nutrients) Calories 10 Calories from Fat 1 Protein 2 g 4% Vitamin A (as beta-carotene) 6900 IU 138% Vitamin K 28 mcg 35% Riboflavin 0.2 mg 10% Niacin 0.5 mg 2% Vitamin B6 0.03 mg 2% Vitamin B12 6 mcg 100% Iron 1 mg 6% Phosphorus 24 mg 2% Iodine 6 mcg Magnesium 6 mg 2% Manganese 0.06 mg 4% Chromium 4.5 mcg 4% Sodium 25 mg 1% Potassium 30 mg <1% C-Phycocyanin 480 mg * Chlorophyll 42 mg * Gamma Linolenic Acid (GLA) 23 mg * Zeaxanthin 2 mg * Inositol 2 mg * ** Typical analysis due to seasonal variations
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
Ultimate Organics
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
USDA Organic
Double Verified Gluten Free
Quality Assurance International Certified Organic
Suggested/Recommended/Usage/Directions
Suggested Use: Take 6 tablets daily with food.
Formula
Spirulina provides a vegetarian source of complete protein. Spirulina platensis contains an exceptionally high amount of C-phycocyanin, a type of algae renowned for its health benefits.
General
VVL 141-100S
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
100% Organic Spirulina 500 mg by Vitamer Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in 100% Organic Spirulina 500 mg by Vitamer Laboratories
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size6 Tablet(s) Dosage formTablet Or Pill Servings per container17 Amounts shown are per serving.
Organic Spirulina
Interacts with327 drugs
Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and...
Organic Spirulina monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
100% Organic Spirulina 500 mg by Vitamer Laboratories Drug Interactions
HelloPharmacist Interaction Report
Vitamer Laboratories' 100% Organic Spirulina can interact with a few medication types.
The most serious concern is with blood thinners and antiplatelet drugs (like warfarin or aspirin) — spirulina has shown anticoagulant effects in the lab, and theoretically could increase bleeding risk, though one small study suggested this is unlikely to happen in practice.
Read the full breakdown — every affected drug type, severity by severity
Two other Moderate-severity interactions are documented. Spirulina may interfere with immunosuppressant medications (drugs that calm down your immune system) because spirulina stimulates immune activity.
It may also increase the risk of low blood sugar (hypoglycemia) if you take diabetes medications, since spirulina itself can lower blood sugar — though it doesn't seem to improve long-term blood sugar control.
Altogether, these interactions span 322 individual medications. Because the exact drugs you take matter, use the medication checker below with your full list before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against 100% Organic Spirulina 500 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in 100% Organic Spirulina 500 mg interact with 327 drugs. Click any drug to see the details.
1 of the 1 ingredient in 100% Organic Spirulina 500 mg interact with drugs. Each result below shows which ingredient is responsible. organic Spirulina
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Spirulina + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Spirulina + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Spirulina + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + Alemtuzumab interactionAlogliptinNesina
How Alogliptin interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Spirulina + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Spirulina + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Spirulina + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Anagrelide interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full Organic Spirulina + Anifrolumab-fnia interactionAnisindioneMiradon
How Anisindione interacts with 100% Organic Spirulina 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Organic SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full Organic Spirulina + Anisindione interactionEach ingredient & the kinds of drugs it affects
For each ingredient in 100% Organic Spirulina 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Spirulina
Anticoagulant/Antiplatelet Drugs
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.
Antidiabetes Drugs
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.
Immunosuppressants
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.
Brand information
Manufacturer and brand details for 100% Organic Spirulina 500 mg, from the product label.
100% Organic Spirulina 500 mg by Vitamer Laboratories: Common Questions
Does 100% Organic Spirulina 500 mg by Vitamer Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does spirulina actually lower blood sugar?
What are the most common side effects?
Can I take this if I'm pregnant or breastfeeding?
Is this product contaminated with heavy metals?
Can spirulina cause an allergic reaction?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if 100% Organic Spirulina 500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind 100% Organic Spirulina 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
100% Organic Spirulina 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 22 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Blue-green Algae 22 references
- Jensen GS, Ginsberg DJ, Huerta P, et al. Consumption of Aphanizomenon flos-aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA 2000;2:50-6.
- Iwasa M, Yamamoto M, Tanaka Y, et al. Spirulina-associated hepatotoxicity. Am J Gastroenterol 2002;97:3212-13. PubMed
- Hayashi O, Katoh T, Okuwaki Y. Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol (Tokyo) 1994;40:431-41.. PubMed
- Vitale S, Miller NR, Mejico LJ, et al. A randomized, placebo-controlled, crossover clinical trial of super blue-green algae in patients with essential blepharospasm or Meige syndrome. Am J Ophthalmol 2004;138:18-32. PubMed
- Mani UV, Desai S, Iyer U. Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. J Nutraceut 2000;2(3):25-32. DOI
- Chiu HF, Yang SP, Kuo YL, et al. Mechanisms involved in the antiplatelet effect of C-phycocyanin. Br J Nutr 2006;95:435-40. PubMed
- Hsiao G, Chou PH, Shen MY, et al. C-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensis. J Agric Food Chem 2005;53:7734-40.
- Katz M, Levine AA, Kol-Degani H, Kav-Venaki L. A compound herbal preparation (CHP) in the treatment of children with ADHD: a randomized controlled trial. J Atten Disord 2010;14:281-91. PubMed
- Madhyastha, H. K., Radha, K. S., Sugiki, M., Omura, S., and Maruyama, M. Purification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cells. Phytomedicine PubMed
- Mazokopakis, E. E., Karefilakis, C. M., Tsartsalis, A. N., Milkas, A. N., and Ganotakis, E. S. Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis). Phytomedicine. 2008;15(6-7):525-527. PubMed
- Halidou, Doudou M., Degbey, H., Daouda, H., Leveque, A., Donnen, P., Hennart, P., and Dramaix-Wilmet, M. [The effect of spiruline during nutritional rehabilitation: systematic review]. Rev.Epidemiol.Sante Publique 2008;56(6):425-431.
- Konno, T., Umeda, Y., Umeda, M., Kawachi, I., Oyake, M., and Fujita, N. [A case of inflammatory myopathy with widely skin rash following use of supplements containing Spirulina]. Rinsho Shinkeigaku 2011;51(5):330-333. PubMed
- Le TM, Knulst AC, Röckmann H. Anaphylaxis to Spirulina confirmed by skin prick test with ingredients of Spirulina tablets. Food Chem Toxicol 2014;74:309-10. PubMed
- Rzymski P, Niedzielski P, Kaczmarek N, Jurczak T, Klimaszyk P. The multidisciplinary approach to safety and toxicity assessment of microalgae-based food supplements following clinical cases of poisoning. Harmful Algae 2015;46:34-42. DOI
- Petrus M, Culerrier R, Campistron M, et al. First case report of anaphylaxis to spirulin: identification of phycocyanin as responsible allergen. Allergy 2010;65(7):924-5. PubMed
- Marles RJ, Barrett ML, Barnes J, et al. United States Pharmacopeia safety evaluation of spirulina. Crit Rev Food Sci Nutr 2011;51(7):593-604. PubMed
- Majdoub H, Ben Mansour M, Chaubet F, et al. Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis. Biochim Biophys Acta 2009;1790(10):1377-81. PubMed
- Cha BG, Kwak HW, Park AR, et al. Structural characteristics and biological performance of silk fibroin nanofiber containing microalgae spirulina extract. Biopolymers 2014;101(4):307-18. PubMed
- Jensen GS, Drapeau C, Lenninger M, Benson KF. Clinical safety of a high dose of phycocyanin-enriched aqueous extract from Arthrospira (Spirulina) platensis: results from a randomized, double-Blind, placebo-controlled study with a focus on anticoagulant ac
- Hamedifard Z, Milajerdi A, Reiner Z, Taghizadeh M, Kolahdooz F, Asemi Z. The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized con
- Moradi S, Zobeiri M, Feizi A, Clark CCT, Entezari MH. The effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative
- Ghanbari F, Amerizadeh A, Behshood P, Moradi S, Asgary S. Effect of microalgae arthrospira on biomarkers of glycemic control and glucose metabolism: a systematic Review and meta-analysis. Curr Probl Cardiol 2022;47(10):100942. PubMed
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