Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Acai Ingredients & Drug Interactions

by Rexall Sundown Naturalist

Acai label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Acai against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Acai is a dietary supplement by Rexall Sundown Naturalist with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, weight loss, energy and vitality.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Acai extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Acai by Rexall Sundown Naturalist

Ask about any prescription or over-the-counter medication and we check it for interactions with Acai by Rexall Sundown Naturalist — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Acai by Rexall Sundown Naturalist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: acai extract. Acai is a berry that's been studied for a range of claims, from skin health to athletic performance to heart health.

The supplement also includes several inactive ingredients (soybean oil, gelatin, glycerin, yellow beeswax, and soy lecithin) that serve as the capsule and carrier.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Acai product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Acai's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“antioxidant support for health and vitality”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence for acai extract doesn't yet support its use for any of the conditions people typically take it for. Our data shows insufficient reliable evidence to rate its effectiveness for aging skin, athletic performance, erectile dysfunction, high cholesterol, or obesity.

That doesn't mean it doesn't work — it means the research isn't there yet to say either way.

The evidence, ingredient by ingredient Acai

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Acai as a whole food is generally well tolerated, but concentrated supplements like this one haven't been thoroughly studied for safety. We don't have enough data on high doses or long-term use.

If you're pregnant or breastfeeding, caution is advised because acai supplements haven't been adequately studied in these situations — talk with your doctor or pharmacist about whether it's right for you.

Side effects, ingredient by ingredient Acai

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Acai.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any diabetes medications (antidiabetes drugs), double-check with your pharmacist before adding this product. Acai may interfere with blood sugar control.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

If you're curious about acai for general wellness and don't take diabetes medications, there's no major red flag here. But if you're on diabetes medication, check with your pharmacist first — acai could affect your blood sugar control.

Because the evidence for what acai actually does is still limited, manage your expectations.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Acai, straight from the product label.

Brand Rexall Sundown Naturalist
Barcode (UPC) 030768199654
Net contents 60 Rapid Release Softgel(s)
Market status On market
Date entered into DSLD Oct 25, 2013
DSLD ID 26120
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Acai by Rexall Sundown Naturalist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
030768199654
IngredientAmount% DV
Acai extract50 mg--

Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Soy Lecithin, Contains <2% of

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

Prod. No. 50225 01B B19965 KAA

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Quality Guaranteed Lab Tested Laboratory tested to meet strict quality control standards for potency, purity and disintegration. 100% Quality Guaranteed.

ACTUAL SIZE

IMPORTANT FACTS YOU SHOULD KNOW Brazillian Acai provides natural flavonoids and antioxidants for health and vitality.* Antioxidants help protect against free radicals that can lead to the premature aging of cells.* Rapid release softgels ensure that the active ingredients of this unique superfood are released quickly into the digestive system for optimum benefit.

Natural Antioxidants and Flavonoids

1-888-VITAHELP

Precautions

WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

KEEP OUT OF REACH OF CHILDREN.

TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

Suggested/Recommended/Usage/Directions

DIRECTIONS: FOR ADULTS TAKE TWO (2) SOFTGELS TWICE DAILY, PREFERABLY WITH MEALS.

Formulation

No yeast, wheat, gluten, milk or milk derivatives, lactose, sugar, preservatives, artificial flavor, sodium.

Storage

STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.

Brand IP Statement(s)

(c)2011

Formula

1000 mg EQUIVALENT PER SERVING

Seals/Symbols

QUALITY ASSURANCE LABORATORY TESTED 100%

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Acai by Rexall Sundown Naturalist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Acai label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Acai by Rexall Sundown Naturalist

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Acai extract

Interacts with
86 drugs
50 mg per serving

Acai is a nutritious Amazonian berry rich in antioxidants and healthy fats, and it is fine to enjoy as a food. However, strong human evidence is lacki...

Acai extract monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Soy Lecithin, Contains <2% of. These complete the product’s ingredient list but are not active constituents.

Interaction report

Acai by Rexall Sundown Naturalist Drug Interactions

Want to check YOUR meds against Acai?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Acai extract 86

Individual Drug Interactions

The ingredients in Acai interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Acai interact with drugs. Each result below shows which ingredient is responsible. Acai extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Acai with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Acai extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking acai with antidiabetes drugs might interfere with glycemic control.
Preliminary clinical research in healthy adults has shown that taking acai may increase or decrease levels of fasting blood glucose.

Likelihood Possible Evidence D
Acai extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Acai, from the product label.

Rexall Sundown Naturalist

See all Rexall Sundown Naturalist products
Name
Rexall Sundown, Inc.
City
Boca Raton
State
FL
ZipCode
33487
Phone Number
1-888-848-2435
Pharmacist Counseling Corner

Acai by Rexall Sundown Naturalist: Common Questions

Does Acai by Rexall Sundown Naturalist interact with any medications?
Yes. Based on its ingredients, Acai has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Acai contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will acai help me lose weight?
The evidence isn't established yet. Our data shows insufficient reliable evidence to rate acai for obesity, so we can't say whether it actually works for weight loss.
Is acai safe if I'm pregnant or breastfeeding?
There isn't enough safety information on acai supplements during pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice — they can help you decide whether it's right for you.
Can acai help with high cholesterol?
The research doesn't yet support that claim. We have insufficient reliable evidence to rate acai for high cholesterol.
What's in the softgel capsule besides acai?
The capsule and carrier contain soybean oil, gelatin, glycerin, yellow beeswax, and soy lecithin. If you're allergic to soy or gelatin, check the label carefully.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Acai is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Acai label
Go deeper

The Full Monographs Behind Acai’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Acai

Interacts with 86 drugs

Acai is a nutritious Amazonian berry rich in antioxidants and healthy fats, and it is fine to enjoy as a food. However, strong human evidence is lacking for the bold health claims often atta...

Read the full Acai monograph →
Sources

Sources & How We Checked

Acai's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Acai 2 references
  1. Udani JK, Singh BB, Singh VJ, Barrett ML. Effects of acai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: a pilot study. Nutr J 2011;10:45.
  2. de Liz S, Cardoso AL, Copetti CLK, et al. Açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) juices improved HDL-c levels and antioxidant defense of healthy adults in a 4-week randomized cross-over study. Clin Nutr. 2020;39(12):3629-3636. PubMed

See these in context on the Acai monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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