ActiFolate Ingredients & Drug Interactions
by Metagenics
What is this page for?
First and foremost: checking ActiFolate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
ActiFolate is a dietary supplement by Metagenics with 1 active ingredient.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of ActiFolate by Metagenics
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about ActiFolate, straight from the product label.
| Brand | Metagenics |
|---|---|
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Oct 25, 2013 |
| DSLD ID | 26243 |
| Product type | Vitamin |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for ActiFolate by Metagenics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Folate | 800 mcg | 200% |
Other ingredients: Microcrystalline Cellulose, Stearic Acid, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
This combination of folates uniquely supports healthy methylation, homocysteine levels, pregnancy, mental function, and other critical functions of folate. Providing three forms of folate may better ensure optimal folate nutrition-even in those with genetic variations in folate metabolism (up to 40% of the population) who may not receive the vital benefits expected from dietary or supplemental folic acid.
ActiFolate(R) is our exclusive proprietary blend of three key forms of folate: folic acid, 5-formyl tetrahydrofolate, and L-5-methyl tetrahydrofolate (L-5-MTHF).
Precautions
CAUTION: If pregnant or nursing, or taking medication, please consult your healthcare practitioner before use.
Keep out of reach of children.
General Statements
Genetic Potential Through Nutrition
Comprehensive Folate Nutrition
0410134 4/12
LAC002F2 PROD ACTF
FDA Statement of Identity
Dietary Supplement
Formulation
Vegetarian
Formulated to Exclude: Wheat, gluten, corn, protein, soy, animal or dairy products, nuts, tree-nuts, fish, crustacean shellfish, colors, artificial flavors, and preservatives.
Brand IP Statement(s)
ActiFolate(R) is our exclusive proprietary blend of three key forms of folate: folic acid, 5-formyl tetrahydrofolate, and L-5-methyl tetrahydrofolate (L-5-MTHF).
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Suggested/Recommended/Usage/Directions
DIRECTIONS: Take one tablet daily or as directed by your healthcare practitioner.
Storage
STORAGE: Keep tightly closed in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
ActiFolate by Metagenics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in ActiFolate by Metagenics
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Folate
Other (inactive) ingredients: Microcrystalline Cellulose, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.
ActiFolate by Metagenics Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in ActiFolate. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for ActiFolate, from the product label.
Metagenics
See all Metagenics products- Name
- METAGENICS, INC. Makers of Professional Quality Supplements
- Street Address
- 100 Ave. La Pata
- City
- San Clemente
- State
- CA
- ZipCode
- 92673
- Web Address
- www.metagenics.com
ActiFolate by Metagenics: Common Questions
Does ActiFolate by Metagenics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if ActiFolate is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
ActiFolate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC