Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Agmatine 750 Unflavored Ingredients & Drug Interactions

by Evlution Nutrition

Agmatine 750 Unflavored label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Agmatine 750 Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Agmatine 750 Unflavored is a dietary supplement by Evlution Nutrition with 1 active ingredient. Its ingredients are commonly taken for pre- and post-workout support, muscle pumps and exercise performance, cognitive support and mood.Based on those ingredients, 258 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Agmatine Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Agmatine 750 Unflavored by Evlution Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Agmatine 750 Unflavored by Evlution Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Agmatine 750 Unflavored by Evlution Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: agmatine sulfate. Agmatine is a compound that forms naturally in your body from the amino acid arginine.

It has been studied for effects on blood pressure, blood sugar, nerve pain, and mood, though evidence for most of these uses is still incomplete. The product comes as an unflavored powder with no other inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Agmatine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support vasodilation nitric oxide and nutrient delivery.
  • We looked for evidence on: Athletic performance, Muscle strength, Exercise performance, Blood flow, Endothelial function.
  • The closest evidence on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Muscle strength.

The evidence for agmatine sulfate isn't established in our data. The product facts list six potential uses — alcohol use disorder, Alzheimer disease, anxiety, athletic performance, autism spectrum disorder, and bipolar disorder — but all of them are rated as having insufficient reliable evidence to know whether it works.

If you're considering agmatine for any of these reasons, talk with your pharmacist or doctor about what the current science actually supports.

The evidence, ingredient by ingredient Agmatine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of agmatine appears generally well tolerated, but long-term safety hasn't been well studied in humans. The most common side effects in small studies were diarrhea, indigestion (dyspepsia), and nausea.

A small number of trial participants taking agmatine sulfate at higher doses reported mild-to-moderate diarrhea and nausea within a few days; these effects went away once they stopped taking it. There isn't enough safety data to know whether agmatine is safe in pregnancy or while breastfeeding — the safety data advises against use during both.

Side effects, ingredient by ingredient Agmatine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Agmatine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 258 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before starting if you take blood pressure medications (antihypertensives) or diabetes drugs — agmatine may increase your risk of low blood pressure or low blood sugar with these. No other interactions are documented for the ingredient we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Agmatine sulfate is one ingredient, and short-term it's generally tolerated well, though digestive upset can happen. The big question is whether it actually works for what you want to use it for — and on that front, the evidence we have is incomplete.

If you take blood pressure or diabetes medication, you'll want to check your specific drugs before starting. Talk with your pharmacist before you use it long-term or if you're pregnant, breastfeeding, or on any prescription.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Agmatine 750 Unflavored, straight from the product label.

Brand Evlution Nutrition
Barcode (UPC) 818901024304
Net contents 2.65 Ounce(s); 75 Gram(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 302077
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Agmatine 750 Unflavored by Evlution Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.75 Gram(s)
Maximum serving Sizes:
0.75 Gram(s)
Servings per container
100
UPC/BARCODE
818901024304
IngredientAmount% DV
Agmatine Sulfate750 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, mix 1 scoop of Agmatine750 with your pre-workout or beverage of choice 15-30 minutes before training. For best results, take an additional serving during training.

Precautions

Warning: Not for use by those with pre-existing medical conditions, those taking any medications or those under the age of 18.

Warning: Not for use by those with pre-existing medical conditions, those taking any medications or those under the age of 18. Keep out of reach of children and pets.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Agmatine750, when combined with regular training, is designed to support: Vasodilation Intense pumps Nitric oxide Nutrient delivery

This product is made in the USA and manufactured by a (GMP) registered facility, and contains ingredients of domestic and international origin.

Nitric Oxide Nutrient delivery Vasodilation & performance support

Vasodilation support Promotes nitric oxide

Vegan/Gluten free

Vegan/Gluten free

General Statements

Instagram Facebook Twitter @EVLSports #EVL

Seals/Symbols

Made In The USA

Formula

750G Agmatine Sulfate

Brand IP Statement(s)

EVL EvlutionNutrition

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Agmatine 750 Unflavored by Evlution Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Agmatine 750 Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Agmatine 750 Unflavored by Evlution Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.75 Gram(s) Dosage formPowder Servings per container100 Amounts shown are per serving.

Agmatine Sulfate

Interacts with
258 drugs
750 mg per serving

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most...

Agmatine Sulfate monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Agmatine 750 Unflavored by Evlution Nutrition Drug Interactions

Want to check YOUR meds against Agmatine 750 Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
258Drugs
258 Moderate

Ingredients driving the most interactions

Agmatine Sulfate 258

Individual Drug Interactions

The ingredients in Agmatine 750 Unflavored interact with 258 drugs. Click any drug to see the details.

1 of the 1 ingredient in Agmatine 750 Unflavored interact with drugs. Each result below shows which ingredient is responsible. Agmatine Sulfate

Each ingredient & the kinds of drugs it affects

For each ingredient in Agmatine 750 Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Agmatine Sulfate2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D
Agmatine Sulfate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Agmatine 750 Unflavored, from the product label.

Evlution Nutrition

See all Evlution Nutrition products
Name
EVLUTION NUTRITION
Street Address
1560 Sawgrass Corporate Parkway, 4th Floor
City
Sunrise
State
Florida
ZipCode
33323
Phone Number
1(855)385-2300
Pharmacist Counseling Corner

Agmatine 750 Unflavored by Evlution Nutrition: Common Questions

Does Agmatine 750 Unflavored by Evlution Nutrition interact with any medications?
Yes. Based on its ingredients, Agmatine 750 Unflavored has a known interaction with 258 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Agmatine 750 Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the most common side effects?
Diarrhea, indigestion, and nausea are the main ones reported in studies. They usually show up within a few days and go away once you stop taking it, but if they're bothersome, stop and talk with your pharmacist.
Is this safe to take long-term?
Short-term use looks okay, but we don't have good data on how safe it is over months or years. If you're thinking about taking this regularly, check in with your pharmacist first.
Can I take this if I'm pregnant or breastfeeding?
No — there isn't enough safety data, so it's best to avoid it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist if you're in either situation and looking for other options.
Does agmatine actually work for the conditions listed?
The evidence isn't solid enough to say yet. All six uses on the label are listed as having insufficient reliable evidence — meaning we don't know if it works. Your pharmacist can tell you what current research does support.
What is agmatine and where does it come from?
Agmatine is a compound your body makes naturally from an amino acid called arginine. This supplement gives you a concentrated dose of it in powder form.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Agmatine 750 Unflavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Agmatine 750 Unflavored label
Go deeper

The Full Monographs Behind Agmatine 750 Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agmatine

Interacts with 258 drugs

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...

Read the full Agmatine monograph →
Sources

Sources & How We Checked

Agmatine 750 Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agmatine 3 references
  1. Piletz JE, Aricioglu F, Cheng JT, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today 2013;18(17-18):880-93. PubMed
  2. Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Safety and efficacy of dietary agmatine sulfate in lumbar disc-associated radiculopathy. An open-label, dose-escalating study followed by a randomized, double-blind, placebo-controlled trial. Pain Med 201 PubMed
  3. Shopsin B. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Acta Neuropsychiatr 2013;25(2):113-8. PubMed

See these in context on the Agmatine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team