Ajwain Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Ajwain against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ajwain is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for vitiligo (loss of skin color), psoriasis, digestive complaints.Based on those ingredients, 954 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ajwain Seed Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ajwain by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Ajwain by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Ajwain by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This liquid supplement contains one active ingredient: ajwain seed extract, dry (also called bishop's weed). The extract also includes alcohol, water, and glycerin as inactive ingredients.
Does it work?
Couldn't assess
We don't have effectiveness data on file for ajwain seed extract in our database, so we can't tell you what it's intended to do or how well it works for any particular use.
How safe is it?
Well-documented data
Ajwain seed extract contains light-sensitizing compounds and carries real safety concerns. Taken by mouth, it's been reported to cause nausea, vomiting, and headache.
Applied to skin, it can trigger photoreactive reactions, phototoxicity, and contact dermatitis — in one case, a person experienced allergic contact reactions after handling the plant. The safety data advises against using this product during pregnancy.
Safety while breastfeeding is unknown, so it's best avoided then too. Because the plant contains potentially harmful compounds, the safety notes emphasize use only under medical supervision.
Meds to double-check
Moderate interaction found
Check with your pharmacist before using this if you take blood thinners or antiplatelet drugs (aspirin, warfarin, clopidogrel, enoxaparin, heparin, and others), medications processed by CYP3A4 (certain anxiety meds, heart drugs, statins, and immunosuppressants), or photosensitizing drugs (tetracyclines, quinolones like ciprofloxacin, sulfa antibiotics, or tricyclic antidepressants). Use the search tool on this page to check your specific medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you take any prescription medication — especially blood thinners, antibiotics, heart drugs, or psychiatric medications — talk to your pharmacist or doctor before starting this product. The photosensitivity risk means you'll need to protect your skin from sunlight carefully while taking it.
This isn't a product to use on your own without professional guidance.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ajwain, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7386004727970 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Dec 21, 2024 |
| DSLD ID | 324735 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ajwain by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Ajwain Seed Extract, Dry | 983 mg | -- |
Other ingredients: Alcohol, Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.
Precautions
We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!
Do not use if you are allergic to any ingredients.
Storage
Store in a cool, dry, dark place.
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Sugar free
Expertly extracted 100% natural Premium product
Organic alcohol
No artificial ingredients, color additives, fillers or binders.
Natural Gluten free
Formula
Trachyspermum ammi
Organic alcohol
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ajwain by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ajwain by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Ajwain Seed Extract, Dry
Interacts with954 drugs
Bishop's Weed (Ammi majus) is a flowering plant whose seeds contain natural light-sensitizing compounds called psoralens, which have been studied main...
Ajwain Seed Extract, Dry monograph & interactionsOther (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Ajwain by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Herbal Terra's Ajwain contains ajwain seed extract (also known as bishop's weed), which has documented interactions with several medication types.
The most serious concern is photosensitizing drugs — bishop's weed can increase your skin's sensitivity to sunlight, and taking it alongside medications like tetracyclines, quinolones (certain antibiotics), sulfa drugs, or tricyclic antidepressants like amitriptyline may heighten that risk.
Read the full breakdown — every affected drug type, severity by severity
Bishop's weed also contains bergapten, a compound that can slow how your liver metabolizes certain medications. This affects a large group of drugs processed by the CYP3A4 enzyme pathway — including some anxiety medications, heart drugs, immunosuppressants, and statins.
Blood levels of these drugs could rise, raising the risk of side effects.
Additionally, bergapten has mild blood-thinning properties. Combined with blood thinners or antiplatelet drugs — aspirin, warfarin, clopidogrel, heparin, enoxaparin, and others — there's a theoretical risk of increased bleeding.
Altogether, these interactions span 944 individual medications. Use the medication checker on this page to look up your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ajwain?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ajwain interact with 954 drugs. Click any drug to see the details.
1 of the 1 ingredient in Ajwain interact with drugs. Each result below shows which ingredient is responsible. Ajwain Seed Extract, Dry
Acetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Dexbrompheniramine, PseudoephedrineSinadrin Plus
How Acetaminophen, Dexbrompheniramine, Pseudoephedrine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Ibuprofen interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has antiplatelet activity.
Read the full Ajwain Seed Extract, Dry + Acetylsalicylic Acid interactionAcitretinSoriatane
How Acitretin interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Acitretin interactionAdagrasibKrazati
How Adagrasib interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Adagrasib interactionAlectinib HydrochlorideAlecensa
How Alectinib Hydrochloride interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Alectinib Hydrochloride interactionAlfentanilAlfenta
How Alfentanil interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Alfuzosin interactionAliskirenTekturna
How Aliskiren interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Aliskiren interactionAlitretinoinPanretin
How Alitretinoin interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Ajwain Seed Extract, Dry + Alitretinoin interactionAlmotriptanAlmogran, Axert
How Almotriptan interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Almotriptan interactionAlogliptinNesina
How Alogliptin interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Alogliptin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Alogliptin, Pioglitazone interactionAlpelisibPiqray
How Alpelisib interacts with Ajwain — through 1 ingredient. Tap an ingredient for the detail:
Ajwain Seed Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Ajwain Seed Extract, Dry + Alpelisib interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ajwain with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Ajwain Seed Extract, Dry
Anticoagulant/Antiplatelet Drugs
Bergapten, a constituent of bishop's weed, has antiplatelet activity. Theoretically, bishop's weed might have additive effects with anticoagulant or antiplatelet drugs and possibly increase the risk of bleeding.
Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro. Theoretically, bishop's weed might inhibit elimination and increase blood levels of drugs metabolized by CYP3A4.
Some drugs metabolized by CYP3A4 include alprazolam (Xanax), amitriptyline (Elavil), amiodarone (Cordarone), buspirone (Buspar), cerivastatin (Baycol), citalopram (Celexa), felodipine (Plendil), fexofenadine (Allegra), itraconazole (Sporanox), ketoconazole (Nizoral), lansoprazole (Prevacid), losartan (Cozaar), lovastatin (Mevacor), ondansetron (Zofran), prednisone (Deltasone, Orasone), sertraline (Zoloft), sibutramine (Meridia), sildenafil (Viagra), simvastatin (Zocor), verapamil (Calan, Covera-HS, Isoptin), and many others.
Photosensitizing Drugs
Bishop's weed constituents seem to cause photosensitivity. Theoretically, concomitant use of bishop's weed with photosensitizing drugs might result in increased photosensitivity.
Some drugs that cause photosensitivity include amitriptyline (Elavil), quinolones (Ciprofloxacin, others), sulfa drugs (Septra, Bactrim, others), and tetracycline.
Brand information
Manufacturer and brand details for Ajwain, from the product label.
Herbal Terra
See all Herbal Terra products- Name
- Herbal Terra LLC
- Phone Number
- +18083857868
- Web Address
- herbalterra.com
Ajwain by Herbal Terra: Common Questions
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How can one product interact with so many drugs?
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What side effects might I experience?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ajwain is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ajwain’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Ajwain's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 8 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bishop's Weed 8 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Kiistala R, Makinen-Kiljunen S, Heikkinen K, et al. Occupational allergic rhinitis and contact urticaria caused by bishop's weed (Ammi majus). Allergy 1999;54:635-9.
- Ossenkoppele PM, van der Sluis WG, van Vloten WA. [Phototoxic dermatitis following the use of Ammi majus fruit for vitiligo]. Ned Tijdschr Geneeskd 1991;135:478-80.
- Malhotra S, Bailey DG, Paine MF, Watkins PB. Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins. Clin Pharmacol Ther 2001;69:14-23. PubMed
- Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
- Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
- Dollahite, J. W., Younger, R. L., and Hoffman, G. O. Photosensitization in cattle and sheep caused by feeding Ammi majus (greater Ammi; Bishop's-Weed). Am J Vet.Res 1978;39(1):193-197. DOI
- Kavli, G. and Volden, G. Phytophotodermatitis. Photodermatol. 1984;1(2):65-75.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC