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Dietary supplement

Alpha GPC Capsules 150 mg Ingredients & Drug Interactions

by Nootropics Depot

Alpha GPC Capsules 150 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Alpha GPC Capsules 150 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Alpha GPC Capsules 150 mg is a dietary supplement by Nootropics Depot with 1 active ingredient. Its ingredients are commonly taken for memory and learning support, age-related cognitive decline, alzheimer's disease and dementia (under study).Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Alpha-Glycerylphosphorylcholine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Alpha GPC Capsules 150 mg by Nootropics Depot

Ask about any prescription or over-the-counter medication and we check it for interactions with Alpha GPC Capsules 150 mg by Nootropics Depot — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Alpha GPC Capsules 150 mg by Nootropics Depot

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: alpha-GPC (alpha-glycerylphosphorylcholine), a compound involved in brain cell membranes and signaling. The capsule also includes inactive ingredients—microcrystalline cellulose, silicon dioxide, tricalcium phosphate, and cellulose—which are fillers and binders that have no therapeutic role.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: memory and cognitive function support.
  • We looked for evidence on: Cognitive function, Alzheimer disease, Vascular dementia, memory, learning, age-related cognitive decline.
  • The strongest evidence on file: Alpha-gpc is rated "Possibly Effective" for Alzheimer disease (Natural Medicines).
  • Also on file: Alpha-gpc is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Vascular dementia.

The evidence for alpha-GPC is mixed. It's rated possibly effective for Alzheimer disease based on available research.

For cognitive function, vascular dementia, stroke, and brain tumor, the evidence isn't strong enough to make a clear rating. If you're considering it for memory or brain health, talk it over with your doctor about what the current evidence supports for your situation.

The evidence, ingredient by ingredient Alpha-gpc

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Alpha-GPC is generally well tolerated in studies, though long-term safety hasn't been fully established. Rare side effects include dizziness, headache, insomnia, nausea, heartburn, and diarrhea.

There's a less common but serious concern: long-term use (at least 2 months) has been rarely associated with an increased risk of stroke compared to non-use or shorter-term use. Pregnancy and lactation safety data isn't on file for this ingredient—talk with your doctor or pharmacist about whether it's appropriate for you.

Side effects, ingredient by ingredient Alpha-gpc

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Alpha-gpc.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you use a scopolamine patch (Transderm Scop) for motion sickness, alpha-GPC may reduce its effectiveness—Minor severity. Check all your current medications with the search tool below before taking this product, since interaction data exists for multiple drug types even though only scopolamine is detailed here.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Alpha-GPC may be worth considering if you're interested in brain health and Alzheimer support, but the evidence for other cognitive uses is still developing. If you take motion sickness patches or any other medications, check them against the tool on this page before starting.

Long-term safety and stroke risk are worth discussing with your doctor or pharmacist, especially if you're thinking of using it for months at a time.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Alpha GPC Capsules 150 mg, straight from the product label.

Brand Nootropics Depot
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD May 24, 2023
DSLD ID 285680
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Alpha GPC Capsules 150 mg by Nootropics Depot, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
IngredientAmount% DV
Alpha-Glycerylphosphorylcholine150 mg--

Other ingredients: Microcrystalline Cellulose, Silicon Dioxide, Tricalcium Phosphate, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Precautions

Disclaimer: Always consult with a qualified health physician before taking any new dietary supplement.

Warning: Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).

FDA Disclaimer Statement

This product is not intended to diagnose, treat, cure or prevent any diseases. These statements have not been evaluated by the Food & Drug Administration.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 1 capsule 1-2 times daily.

Storage

Storage: Store in a cool and dry place. Keep away from direct sunlight and heat.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Alpha GPC Capsules 150 mg by Nootropics Depot label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Alpha GPC Capsules 150 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Alpha GPC Capsules 150 mg by Nootropics Depot

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Alpha-Glycerylphosphorylcholine

Interacts with
16 drugs
150 mg per serving

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition...

Alpha-Glycerylphosphorylcholine monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Silicon Dioxide, Tricalcium Phosphate, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Alpha GPC Capsules 150 mg by Nootropics Depot Drug Interactions

Want to check YOUR meds against Alpha GPC Capsules 150 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Alpha-Glycerylphosphorylcholine 16

Individual Drug Interactions

The ingredients in Alpha GPC Capsules 150 mg interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Alpha GPC Capsules 150 mg interact with drugs. Each result below shows which ingredient is responsible. Alpha-Glycerylphosphorylcholine

Each ingredient & the kinds of drugs it affects

For each ingredient in Alpha GPC Capsules 150 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Alpha-Glycerylphosphorylcholine1 drug type · 16 drugs

Scopolamine (Transderm Scop)

Theoretically, alpha-GPC might decrease the effects of scopolamine.
A small clinical study shows that alpha-GPC can partially counteract the attention and memory impairment effects caused by scopolamine given intramuscularly. Whether alpha-GPC can decrease the beneficial anti-motion sickness effects of the scopolamine patch (Transderm Scop) is unclear.

Likelihood Possible Evidence B
Alpha-Glycerylphosphorylcholine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Alpha GPC Capsules 150 mg, from the product label.

Nootropics Depot

See all Nootropics Depot products
Name
Nootropics Depot
Street Address
8380 S. Kyrene Rd. Ste. 110
City
Tempe
State
AZ
ZipCode
85284
Web Address
nootropicsdepot.com
Pharmacist Counseling Corner

Alpha GPC Capsules 150 mg by Nootropics Depot: Common Questions

Does Alpha GPC Capsules 150 mg by Nootropics Depot interact with any medications?
Yes. Based on its ingredients, Alpha GPC Capsules 150 mg has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Alpha GPC Capsules 150 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does alpha-GPC really help with memory and Alzheimer disease?
For Alzheimer disease, the evidence is rated possibly effective—there's some support, but it's not conclusive. For general cognitive function and memory, the evidence isn't strong enough to rate yet. Your doctor can help you decide if it's right for your situation.
Are there side effects I should watch for?
Alpha-GPC is generally well tolerated, but rare side effects include dizziness, headache, insomnia, nausea, and heartburn. There's also a less common but serious concern: long-term use (2 months or longer) has been rarely linked to stroke risk, so this is worth discussing with your doctor if you're planning extended use.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data on file for alpha-GPC in pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether it's appropriate for you in those situations.
Will this interact with my motion sickness patch?
Yes—alpha-GPC may decrease how well a scopolamine patch (Transderm Scop) works. A small study showed alpha-GPC can partly counteract the cognitive effects of scopolamine, so it might also weaken its motion sickness benefits. Check with your doctor or pharmacist before combining them.
What exactly is alpha-GPC?
Alpha-GPC is a compound found naturally in your brain that's involved in cell membranes and how brain cells signal to each other. It's extracted and concentrated in this supplement form.
How long does it take to work?
That depends on your goal and the condition being treated—the facts we hold don't specify a typical timeframe. Your doctor or pharmacist can give you a better sense of what to expect.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Alpha GPC Capsules 150 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Alpha GPC Capsules 150 mg label
Go deeper

The Full Monographs Behind Alpha GPC Capsules 150 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Alpha-gpc

Interacts with 16 drugs

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition in people with dementia, but evidence i...

Read the full Alpha-gpc monograph →
Sources

Sources & How We Checked

Alpha GPC Capsules 150 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Alpha-gpc 4 references
  1. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to the evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res 1991;19:330-41.
  2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, et al. Alpha-glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994;717:253-69. PubMed
  3. Canal N, Franceschi M, Alberoni M, et al. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine. Int J Clin Pharmacol Ther Toxicol 1991;29:103-7.
  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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