American Ginseng Ingredients & Drug Interactions
by Energique
What is this page for?
First and foremost: checking American Ginseng against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
American Ginseng is a dietary supplement by Energique with 1 active ingredient. Its ingredients are commonly taken for stress and energy support, immune support and colds, blood sugar management.Based on those ingredients, 217 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are American Ginseng. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against American Ginseng by Energique
Ask about any prescription or over-the-counter medication and we check it for interactions with American Ginseng by Energique — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of American Ginseng by Energique
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This liquid contains one active ingredient: American Ginseng. The product also includes water and ethanol as inactive ingredients — the ethanol is a preservative commonly used in liquid herbal supplements.
Does it work?
Moderate evidence
The evidence on American Ginseng points to possibly effective for upper respiratory tract infections (URTI). For anemia of chronic disease and breast cancer, the evidence we hold is insufficient to rate whether it works — the research simply isn't solid enough to draw a conclusion.
How safe is it?
Well-documented data
American Ginseng is generally well tolerated in the short term for healthy adults, though quality and dosing vary between products and long-term safety hasn't been well studied. Headache has been reported by some users.
The safety data advises against use during pregnancy and while breastfeeding because there isn't enough information to know it's safe in those situations.
Meds to double-check
Major interaction found
Before you start, double-check your medications against warfarin (Coumadin), immunosuppressants, diabetes drugs, and monoamine oxidase inhibitors (MAOIs) using the search tool on this page. These are the drug types with documented interactions — warfarin carries the most serious risk.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
American Ginseng may help with upper respiratory infections, but it's not for everyone. If you take warfarin, immunosuppressants, diabetes drugs, or MAOIs, check with your pharmacist first — the interactions can be significant.
Pregnant or breastfeeding? Skip it.
Otherwise, a short course is typically safe, but talk to your pharmacist about your full medication list.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about American Ginseng, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for American Ginseng by Energique, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1.5 mL | -- |
| American Ginseng | 0 NP | -- |
Other ingredients: Water, Purified, Ethanol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Warnings: If pregnant or breast-feeding, ask a health professional before use.
Consult a physician for use in children under 12 years of age. Keep out of reach of children.
Do not use if tamper evident seal is broken or missing.
Storage
Store in a cool, dry place.
Suggested/Recommended/Usage/Directions
Suggested use: 10 to 30 drops in water or juice 3 times daily or as otherwise directed. Shake well before use.
Brand IP Statement(s)
Energique Since 1987
FDA Statement of Identity
Herbal Supplement
Formula
Panax quinquefolius (root)
Formulation
Organic and wild-crafted herbs used when possible.
Organic and wild-crafted herbs used when possible.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
American Ginseng by Energique label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in American Ginseng by Energique
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.5 mL Dosage formLiquid Servings per container39 Amounts shown are per serving.
Proprietary Blend
Other (inactive) ingredients: Water, Purified, Ethanol. These complete the product’s ingredient list but are not active constituents.
American Ginseng by Energique Drug Interactions
HelloPharmacist Interaction Report
Energique American Ginseng is a single-ingredient liquid supplement that does interact with several medication types.
The most serious concern is warfarin (Coumadin), a blood thinner — American ginseng appears to decrease how well warfarin works by lowering your INR (a measure of blood thinning), which could reduce its protective effect against clots.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to check if you take immunosuppressants (drugs that calm your immune system after transplant or for certain conditions), diabetes medications, or monoamine oxidase inhibitors (MAOIs) — older antidepressants like phenelzine (Nardil). American ginseng may interfere with all three: it might reduce immunosuppressant effectiveness, increase the risk of low blood sugar (hypoglycemia) when combined with diabetes drugs, and case reports suggest it can cause insomnia, headache, tremors, or mood changes with MAOIs.
Altogether, these interactions span 212 individual medications. Please run your exact prescriptions through the medication checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against American Ginseng?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in American Ginseng interact with 217 drugs. Click any drug to see the details.
1 of the 1 ingredient in American Ginseng interact with drugs. Each result below shows which ingredient is responsible. American Ginseng
EfalizumabRaptiva
How Efalizumab interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Efalizumab interactionEfgartigimod Alfa-fcabVyvgart
How Efgartigimod Alfa-fcab interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Efgartigimod Alfa-fcab interactionElranatamabElrexfio
How Elranatamab interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Elranatamab interactionEmapalumab-lzsgGamifant
How Emapalumab-lzsg interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Emapalumab-lzsg interactionEmpagliflozinJardiance
How Empagliflozin interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Empagliflozin, Metformin Hydrochloride interactionEpcoritamab-byspEpkinly
How Epcoritamab-bysp interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Epcoritamab-bysp interactionErtugliflozinSteglatro
How Ertugliflozin interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Ertugliflozin interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Ertugliflozin, Metformin Hydrochloride interactionEtanercept-szzsErelzi
How Etanercept-szzs interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Etanercept-szzs interactionEtanercept-ykroEticovo
How Etanercept-ykro interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Etanercept-ykro interactionEtrasimodVelsipity
How Etrasimod interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Etrasimod interactionExenatideBydureon, Byetta
How Exenatide interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Exenatide interactionExenatide SyntheticBydureon BCISE
How Exenatide Synthetic interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Exenatide Synthetic interactionFingolimodGilenya, Tascenso ODT
How Fingolimod interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Fingolimod interactionFludrocortisoneFlorinef Acetate
How Fludrocortisone interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Fludrocortisone interactionFluorouracil (iv)Fluorouracil
How Fluorouracil (iv) interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Fluorouracil (iv) interactionFlupenthixolFluanxol
How Flupenthixol interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Flupenthixol interactionFostamatinibTavalisse
How Fostamatinib interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Fostamatinib interactionGlatiramer AcetateCopaxone
How Glatiramer Acetate interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Glatiramer Acetate interactionGliclazideDiamicron
How Gliclazide interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Gliclazide interactionGlimepirideAmaryl
How Glimepiride interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Glimepiride interactionGlipizideGlucotrol, Glucotrol XL
How Glipizide interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Glipizide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Glipizide, Metformin interactionGlofitamab-gxbmColumvi
How Glofitamab-gxbm interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengImmunosuppressants Moderate
Interaction Summary
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
Read the full American Ginseng + Glofitamab-gxbm interactionGlucagonBaqsimi, Glucagon
How Glucagon interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Glucagon interactionGlucoseIV Glucose
How Glucose interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Glucose interactionGlyburideAlbert Glyburide, Diabeta, Glycron, Glynase, Glynase PresTab, Micronase +1 more
How Glyburide interacts with American Ginseng — through 1 ingredient. Tap an ingredient for the detail:
American GinsengAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full American Ginseng + Glyburide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in American Ginseng with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
American Ginseng
Warfarin (Coumadin)
American ginseng seems to decrease the effectiveness of warfarin therapy.
Healthy patients receiving warfarin 5 mg daily, who also take American ginseng 1 gram twice daily, seem to have a significantly reduced international normalized ratio (INR).
Antidiabetes Drugs
Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
American ginseng seems to lower postprandial blood glucose. Theoretically, concomitant use with antidiabetes drugs might enhance blood glucose lowering effects and possibly cause hypoglycemia.
Immunosuppressants
Theoretically, American ginseng use might interfere with immunosuppressive therapy.
American ginseng seems to stimulate immune function. Theoretically, American ginseng might decrease the effectiveness of immunosuppressant drugs.
Monoamine Oxidase Inhibitors (Maois)
Theoretically, American ginseng can interfere with MAOI therapy.
There is one case report of insomnia, headache, and tremors when an unspecified ginseng product was used with phenelzine (Nardil), an MAOI. There is also one case report of hypomania when an unspecified ginseng product was used with phenelzine. Theoretically, American ginseng may interfere with MAOI therapy.
Brand information
Manufacturer and brand details for American Ginseng, from the product label.
Energique
See all Energique products- Name
- Energique, Inc.
- Street Address
- 201 Apple Blvd.
- City
- Woodbine
- State
- IA
- ZipCode
- 51579
- Phone Number
- 800.869.8078
American Ginseng by Energique: Common Questions
Does American Ginseng by Energique interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What's the liquid made of besides the ginseng?
Does it really help with colds?
Are there any side effects I should know about?
Can I take this long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if American Ginseng is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind American Ginseng’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
American Ginseng's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
American Ginseng 12 references
- Shader RI, Greenblatt DJ. Phenelzine and the dream machine-ramblings and reflections. J Clin Psychopharmacol 1985;5:65. PubMed
- Jones BD, Runikis AM. Interaction of ginseng with phenelzine. J Clin Psychopharmacol 1987;7:201-2. PubMed
- Janetzky K, Morreale AP. Probable interaction between warfarin and ginseng. Am J Health Syst Pharm 1997;54:692-3. PubMed
- Vuksan V, Sievenpiper JL, Koo VY, et al. American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000;160:1009-13. PubMed
- Vuksan V, Stavro MP, Sievenpiper JL, et al. Similar postprandial glycemic reductions with escalation of dose and administration time of American ginseng in type 2 diabetes. Diabetes Care 2000;23:1221-6. PubMed
- Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
- McElhaney JE, Gravenstein S, Cole SK, et al. A Placebo-Controlled Trial of a Proprietary Extract of North American Ginseng (CVT-E002) to Prevent Acute Respiratory Illness in Institutionalized Older Adults. J Am Geriatr Soc 2004;52:13-9. PubMed
- Yuan CS, Wei G, Dey L, et al. American ginseng reduces warfarin's effect in healthy patients: a randomized, controlled trial. Ann Intern Med 2004;141:23-7.
- Predy GN, Goel V, Lovlin R, et al. Efficacy of an extract of North American ginseng containing poly-furanosyl-pyranosyl-saccharides for preventing upper respiratory tract infections: a randomized controlled trial. CMAJ 2005;173:1043-8.. PubMed
- McElhaney JE, Goel V, Toane B, et al. Efficacy of COLD-fX in the prevention of respiratory symptoms in community-dwelling adults: a randomized, double-blinded, placebo controlled trial. J Altern Complement Med 2006;12:153-7. PubMed
- Predy GN, Goel V, Lovlin RE, et al. Immune modulating effects of daily supplementation of COLD-fX (a proprietary extract of North American ginseng) in healthy adults. J Clin Biochem Nutr 2006;39:162-167. DOI
- Stavro PM, Woo M, Leiter LA, et al. Long-term intake of North American ginseng has no effect on 24-hour blood pressure and renal function. Hypertension 2006;47(4):791-6. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC