Interactions on record — worth a quick check against your medications. Based on 3 of 9 ingredients. Check your meds →
Dietary supplement

Anabolic XT Ingredients & Drug Interactions

by SNS Serious Nutrition Solutions

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Anabolic XT is a dietary supplement by SNS Serious Nutrition Solutions with 9 active ingredients. Its ingredients are commonly taken for antioxidant support, heart and circulation health, blood sugar support.Based on those ingredients, 1,072 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are BioPerine, Black Ginger Rhizome Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Anabolic XT by SNS Serious Nutrition Solutions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 9 of its 9 active ingredients.
  • “Anabolic XT Ultimate Anabolic Complex” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Anabolic XT Absorption Enhancement Complex” is a proprietary blend — the label doesn't break down how much of each component you get.

Anabolic XT contains 9 active ingredients, including BioPerine (black pepper extract for absorption), Ecklonia cava extract (a seaweed ingredient), and several proprietary blends: the Anabolic XT Ultimate Anabolic Complex, the Anabolic XT Absorption Enhancement Complex, and individual components like SA3X, SR10X, AstraGin, G670X, C30X, and black ginger rhizome extract. The product also contains inactive ingredients — cellulose, titanium dioxide, rice flour, and magnesium stearate — which are standard capsule fillers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: lean muscle gains and strength with anabolic support.
  • We looked for evidence on: Athletic performance, Muscle hypertrophy, Strength gains, Body composition, Muscle retention.
  • The closest evidence on file: Black Pepper is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Ecklonia Cava is rated "Insufficient Reliable Evidence To Rate" for Athletic performance.

The evidence for BioPerine itself is limited across the conditions it's studied for — hay fever, asthma, athletic performance, headache, depression, and diarrhea all have insufficient reliable evidence to rate. Ecklonia cava extract shows possibly effective evidence for high cholesterol (hypercholesterolemia), though it's been studied mainly short-term.

For athletic performance, cancer, and diabetes, the evidence for Ecklonia cava is insufficient. We hold no effectiveness data on the other active ingredients in this product.

The evidence, ingredient by ingredient Ecklonia Cava Ginger Black Pepper

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

BioPerine is generally well tolerated when used in food amounts or as a single medicinal dose; the most common side effects are a burning aftertaste, indigestion, and reduced taste perception. Concentrated piperine supplements should be used cautiously and only under medical guidance.

Serious allergic reactions are rare but possible in sensitive individuals. Ecklonia cava extract carries caution flags: long-term safety isn't well established, and seaweed can contain high iodine levels.

Single cases of hair loss, nausea, indigestion, and diarrhea were reported in trials. The safety data advises against Ecklonia cava during breastfeeding.

We hold no pregnancy or breastfeeding data for BioPerine or the other active ingredients.

Side effects, ingredient by ingredient Ecklonia Cava Ginger Black Pepper

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Black Pepper, Ginger.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 1,073 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Anabolic XT, double-check if you take any blood pressure or heart medications (propranolol), seizure medications (phenytoin), cholesterol medications (atorvastatin), breathing medications (theophylline), HIV medications (nevirapine), tuberculosis antibiotics (rifampin), immunosuppressants (cyclosporine), or sedatives (pentobarbital) — BioPerine in this product is documented to raise blood levels of all of these. If you do, run your exact medications through the checker below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking to support athletic performance or cholesterol levels, the evidence for most ingredients here is either limited or missing. If you take any heart, blood pressure, seizure, HIV, antibiotic, immunosuppressant, or breathing medications, you must check your specific drugs against our interaction tool before starting — BioPerine can raise blood levels of several of them.

Talk with your pharmacist about whether this product is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Anabolic XT, straight from the product label.

Brand SNS Serious Nutrition Solutions
Barcode (UPC) 850008039720
Net contents 180 Veggie Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 318422
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Anabolic XT by SNS Serious Nutrition Solutions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
850008039720
IngredientAmount% DV
BioPerine10 mg--
Eucommia ulmoides Bark Extract900 mg--
Ecklonia cava extract600 mg--
SA3X500 mg--
SR10X1500 mg--
Anabolic XT Ultimate Anabolic Complex0 NP--
AstraGin25 mg--
G670X500 mg--
C30X350 mg--
Black Ginger Rhizome Extract100 mg--
Anabolic XT Absorption Enhancement Complex0 NP--

Other ingredients: Cellulose, Titanium Dioxide, Rice Flour, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Hardcore natural anabolic powered by natural phytoandrogens SNS Anabolic XT is a hardcore natural anabolic formula backed by clinically researched ingredients designed to provide both anabolic and anti-catabolic benefits to support dramatic lean muscle, strength, performance, and much more.

Anabolic XT Highlights/Supports: Incredible lean muscle gains Hardcore strength gains Fat loss & improved body-composition Optimal athletic performance Lean muscle retention while dieting Improved recovery between sets & workouts Increased endurance/reduced fatigue Increases in free & total testosterone levels Improved sexual performance & libido Improved sense of well-being Longevity & anti-aging properties Potent anabolic & anti-catabolic benefits Powered by natural phytoandrogens 9 high end active ingredients Clinically researched key ingredients

Hardcore natural anabolic Hardcore lean muscle & strength Powerful anabolic & anti-catabolic benefits Powered by natural phytoandrogens 9 high end active ingredients

Allergen information: Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients.

Suggested/Recommended/Usage/Directions

SNS Anabolic XT can be stacked with Optimize-T, VasoForce XT, VasoForce Rush, Lean Edge, Thermagize XT, Joint Support XT, Stress & Anxiety Support, or a variety of other SNS products for improved synergistic results.

Suggested use: As a dietary supplement, take 3 capsules twice per day.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

To report a serious adverse event, or obtain product information, contact SNS at [email protected]

Warning: This product is intended for healthy adults over 18 years of age. Keep stored in a cool, dry place away from children and animals.

Do not use this product if you are pregnant or nursing. Consult your physician before using this or any dietary supplement, especially if you are taking any medication or suffer from any health condition(s).

Allergen information: Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients. Produced in a GMP facility that may process other ingredients containing these allergens.

Formula

1,500 mg Symplocos 900 mg Eucommia Ulmoides 600 mg Ecklonia Cava 500 mg Spilanthes 350 mg Cistanche 100 mg Black Ginger

SA3X SR10X AstraGin BioPerine G70X C30X

General Statements

30 day supply

FDA Statement of Identity

Dietary Supplement

Storage

Keep stored in a cool, dry place away from children and animals.

See for yourself

Anabolic XT by SNS Serious Nutrition Solutions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Anabolic XT by SNS Serious Nutrition Solutions

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Anabolic XT Ultimate Anabolic Complex

0 NP per serving

Anabolic XT Absorption Enhancement Complex

0 NP per serving

Other (inactive) ingredients: Cellulose, Titanium Dioxide, Rice Flour, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Anabolic XT by SNS Serious Nutrition Solutions Drug Interactions

Want to check YOUR meds against Anabolic XT?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,072Drugs
976 Moderate 96 Minor

Ingredients driving the most interactions

BioPerine 1,019

Each ingredient & the kinds of drugs it affects

For each ingredient in Anabolic XT with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

BioPerine17 drug types · 1,019 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, black pepper might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
In vitro research shows that piperine, a constituent of black pepper, seems to inhibit platelet aggregation. This has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, black pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that piperine, a constituent of black pepper, can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Atorvastatin (Lipitor)

Theoretically, black pepper might increase blood levels of atorvastatin.
Animal research shows that taking piperine, a constituent of black pepper, 35 mg/kg can increase the maximum serum concentration of atorvastatin three-fold. This has not been reported in humans.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, black pepper might increase the effects and side effects of cyclosporine.
In vitro research shows that piperine, a constituent of black pepper, increases the bioavailability of cyclosporine. This has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, black pepper might increase levels of drugs metabolized by CYP2D6.
In vitro research suggests that some constituents of black pepper inhibit CYP2D6. This has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, black pepper might increase levels of drugs metabolized by CYP3A4.
In vitro research and pharmacokinetic simulation data suggest that piperine, a constituent of black pepper, as well as the pepper fruit seem to inhibit CYP3A4. This has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, black pepper might increase blood levels of lithium due to its diuretic effects. The dose of lithium might need to be reduced.
Black pepper is thought to have diuretic properties.

Likelihood Probable Evidence D
Nevirapine (Viramune)

Black pepper might increase blood levels of nevirapine.
Clinical research shows that piperine, a constituent of black pepper, increases the plasma concentration of nevirapine. However, no adverse effects were observed in this study.

Likelihood Probable Evidence D
P-Glycoprotein Substrates

Theoretically, black pepper might increase levels of P-glycoprotein substrates.
In vitro research shows that piperine, a constituent of black pepper, seems to inhibit P-glycoprotein.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, black pepper might increase the sedative effects of pentobarbital.
Animal research shows that piperine, a constituent of black pepper, increases pentobarbital-induced sleeping time.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Black pepper might increase blood levels of phenytoin.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption, slow elimination, and increase levels of phenytoin. Taking a single dose of black pepper 1 gram along with phenytoin seems to double the serum concentration of phenytoin. Consuming a soup with black pepper providing piperine 44 mg/200 mL of soup along with phenytoin also seems to increase phenytoin levels when compared with consuming the same soup without black pepper.

Likelihood Possible Evidence B
Propranolol (Inderal)

Black pepper might increase blood levels of propranolol.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of propranolol.

Likelihood Possible Evidence B
Rifampin (Rifadin)

Black pepper might increase blood levels of rifampin.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and serum levels of rifampin.

Likelihood Possible Evidence B
Theophylline

Black pepper might increase blood levels of theophylline.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of theophylline.

Likelihood Possible Evidence D
Amoxicillin (Amoxil, Trimox)

Theoretically, black pepper might increase the effects and side effects of amoxicillin.
Animal research shows that taking piperine, a constituent of black pepper, with amoxicillin increases plasma levels of amoxicillin. This has not been reported in humans.

Likelihood Possible Evidence D
Carbamazepine (Tegretol)

Theoretically, black pepper might increase blood levels of carbamazepine, potentially increasing the effects and side effects of carbamazepine.
One clinical study in patients taking carbamazepine 300 mg or 500 mg twice daily shows that taking a single 20 mg dose of purified piperine, a constituent of black pepper, increases carbamazepine levels. Piperine may increase carbamazepine absorption by increasing blood flow to the GI tract, increasing the surface area of the small intestine, or inhibiting cytochrome P450 3A4 (CYP3A4) in the gut wall. Absorption was significantly increased by 7-10 mcg/mL/hour. The time to eliminate carbamazepine was also increased by 4-8 hours. Although carbamazepine levels were increased, this did not appear to increase side effects. In vitro research also shows that piperine can increase carbamazepine levels by 11% in a time-dependent manner.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, black pepper might decrease levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research suggests that black pepper induces CYP1A2. This has not been reported in humans.

Likelihood Possible Evidence D

Black Ginger Rhizome Extract14 drug types · 1,007 drugs

Anticoagulant/Antiplatelet Drugs

Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, research is conflicting.
Laboratory research suggests that ginger inhibits thromboxane synthetase and decreases platelet aggregation. However, this has not been demonstrated unequivocally in humans, with mixed results from clinical trials. Theoretically, excessive amounts of ginger might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Animal and human research suggests that ginger might increase insulin levels and/or decrease blood glucose levels.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Ginger might increase or decrease the levels of CYP3A4 substrates.
In vitro research and some case reports suggest that ginger inhibits CYP3A4 activity. Three case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are CYP3A4 substrates (imatinib, dabrafenib, and crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Conversely, other in vitro research suggests that ginger induces CYP3A4 activity, leading to reduced levels of CYP3A4 substrates. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Losartan (Cozaar)

Theoretically, ginger might increase levels of losartan and the risk of hypotension.
In animal research, ginger increased the levels and hypotensive effects of a single dose of losartan. It is not clear if ginger alters the concentration or effects of losartan when taken continuously. Additionally, this interaction has not been shown in humans.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Ginger may have antiplatelet effects and increase the risk of bleeding if used with nifedipine.
Clinical research shows that combined treatment with ginger 1 gram plus nifedipine 10 mg significantly inhibits platelet aggregation when compared to nifedipine or ginger alone.

Likelihood Possible Evidence B
P-Glycoprotein Substrates

Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
In vitro research and case reports suggest that ginger inhibits drug efflux by P-gp, potentially increasing absorption and serum levels of P-gp substrates. Two case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are P-gp substrates (trametinib, crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.

Likelihood Possible Evidence D
Phenprocoumon (Marcoumar, Others)

Ginger might increase the risk of bleeding with phenprocoumon.
Phenprocoumon, a warfarin-related anticoagulant, might increase the international normalized ratio (INR) when taken with ginger. There is one case report of a 76-year-old woman with a stable INR on phenprocoumon that increased to greater than 10 when she began consuming dried ginger and ginger tea.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Ginger might increase the risk of bleeding with warfarin.
Laboratory research suggests that ginger might inhibit thromboxane synthetase and decrease platelet aggregation. In one case report, ginger increased the INR when taken with phenprocoumon, which has similar pharmacological effects as warfarin. In another case report, ginger increased the INR when taken with a combination of warfarin, hydrochlorothiazide, and acetaminophen. A longitudinal analysis suggests that taking ginger increases the risk of bleeding in patients taking warfarin for at least 4 months. However, research in healthy people suggests that ginger has no effect on INR, or the pharmacokinetics or pharmacodynamics of warfarin. Until more is known, monitor INRs closely in patients taking large amounts of ginger.

Likelihood Possible Evidence B
Calcium Channel Blockers

Theoretically, taking ginger with calcium channel blockers might increase the risk of hypotension.
Some animal and in vitro research suggests that ginger has hypotensive and calcium channel-blocking effects. Another animal study shows that concomitant administration of ginger and the calcium channel blocker amlodipine leads to greater reductions in blood pressure when compared with amlodipine alone.

Likelihood Unlikely Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, when taken prior to cyclosporine, ginger might decrease cyclosporine levels.
In an animal model, ginger juice taken 2 hours prior to cyclosporine administration reduced the maximum concentration and area under the curve of cyclosporine by 51% and 40%, respectively. This effect was not observed when ginger juice and cyclosporine were administered at the same time.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ginger might increase the levels of CYP1A2 substrates.
In vitro research shows that ginger inhibits CYP1A2 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, ginger might increase the levels of CYP2B6 substrates.
In vitro research shows that ginger inhibits CYP2B6 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, ginger might increase the levels of CYP2C9 substrates.
In vitro research shows that ginger inhibits CYP2C9 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Metronidazole (Flagyl)

Theoretically, ginger might increase levels of metronidazole.
In an animal model, ginger increased the absorption and plasma half-life of metronidazole. In addition, the elimination rate and clearance of metronidazole was significantly reduced.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Anabolic XT, from the product label.

SNS Serious Nutrition Solutions

See all SNS Serious Nutrition Solutions products
Name
Serious Nutrition Solutions, LLC.
City
Danville
State
VA
ZipCode
24540
Web Address
www.SeriousNutritionSolutions.com
Pharmacist Counseling Corner

Anabolic XT by SNS Serious Nutrition Solutions: Common Questions

Does Anabolic XT by SNS Serious Nutrition Solutions interact with any medications?
Yes. Based on its ingredients, Anabolic XT has a known interaction with 1,072 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Anabolic XT contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is BioPerine and what does it do in this product?
BioPerine is an extract from black pepper. It's included here because it can increase how your body absorbs other ingredients — that's why it's in the absorption enhancement complex. However, this same effect means it can also raise blood levels of certain medications, so it's important to check before you start if you're on any prescriptions.
Does this product work for building muscle or athletic performance?
The evidence for the active ingredients here — including BioPerine and Ecklonia cava — doesn't establish that they work for athletic performance. We have insufficient reliable evidence to rate them for that use. If athletic performance is your goal, talk with your pharmacist or doctor about what the research actually supports.
What are the most common side effects I might notice?
BioPerine, the main ingredient we have side-effect data for, typically causes a burning aftertaste, indigestion, or reduced taste perception. A small number of trial participants taking Ecklonia cava reported nausea, indigestion, or diarrhea. Serious allergic reactions are rare but possible if you're sensitive to black pepper.
Is this safe to take while breastfeeding?
We have no pregnancy or breastfeeding data on file for BioPerine or most of the other active ingredients. For Ecklonia cava, the safety data advises against use during breastfeeding. Because the safety information isn't complete, talk with your doctor or pharmacist before starting this product if you're breastfeeding.
Can I take this if I have high cholesterol?
Ecklonia cava extract in this product shows possibly effective evidence for high cholesterol. However, studies have been short-term, and long-term safety isn't well established. If you take a cholesterol medication like atorvastatin, BioPerine can raise its blood levels, so check with us first. Talk to your doctor about whether this product fits your overall cholesterol plan.
What ingredients are in here that I should know about?
This product has 9 active ingredients, but we have limited or no interaction and effectiveness data on several of them — Eucommia ulmoides bark, SA3X, SR10X, AstraGin, G670X, C30X, and black ginger rhizome. The ones we do have data for are BioPerine (black pepper) and Ecklonia cava extract (seaweed). If you're concerned about a specific ingredient, ask us.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Anabolic XT label
Sources

Sources & How We Checked

Anabolic XT's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 94 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Pepper 29 references
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Bano G, Amla V, Raina RK, et al. The effect of piperine on pharmacokinetics of phenytoin in healthy volunteers. Planta Med 1987;53:568-9. PubMed
  4. Bano G, et al. Effect of piperine on bioavailability and pharmacokinetics of propranolol and theophylline in healthy volunteers. Eur J Clin Pharmacol 1991;41;615-7. PubMed
  5. Cohle SD, Trestrail JD III, Graham MA, et al. Fatal pepper aspiration. Am J Dis Child 1988;142:633-6. PubMed
  6. Bhardwaj RK, Glaeser H, Becquemont L, et al. Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4. J Pharmacol Exp Ther 2002;302:645-50. PubMed
  7. Velpandian T, Jasuja R, Bhardwaj RK, et al. Piperine in food: interference in the pharmacokinetics of phenytoin. Eur J Drug Metab Pharmacokinet 2001;26:241-7. PubMed
  8. Pattanaik S, Hota D, Prabhakar S, et al. Pharmacokinetic interaction of a single dose of piperine with steady-state carbamazepine in epilepsy patients. Phytother Res 2009;23:1281-6.
  9. Munakata, M., Kobayashi, K., Niisato-Nezu, J., Tanaka, S., Kakisaka, Y., Ebihara, T., Ebihara, S., Haginoya, K., Tsuchiya, S., and Onuma, A. Olfactory stimulation using black pepper oil facilitates oral feeding in pediatric patients receiving long-term en
  10. Myers, B. M., Smith, J. L., and Graham, D. Y. Effect of red pepper and black pepper on the stomach. Am J Gastroenterol 1987;82(3):211-214.
  11. Raghavendra, R. H. and Naidu, K. A. Spice active principles as the inhibitors of human platelet aggregation and thromboxane biosynthesis. Prostaglandins Leukot.Essent.Fatty Acids 2009;81(1):73-78. PubMed
  12. Subehan, Usia, T., Kadota, S., and Tezuka, Y. Mechanism-based inhibition of human liver microsomal cytochrome P450 2D6 (CYP2D6) by alkamides of Piper nigrum. Planta Med 2006;72(6):527-532.
  13. Kasibhatta, R. and Naidu, M. U. Influence of piperine on the pharmacokinetics of nevirapine under fasting conditions: a randomised, crossover, placebo-controlled study. Drugs R.D. 2007;8(6):383-391. PubMed
  14. Usia, T., Iwata, H., Hiratsuka, A., Watabe, T., Kadota, S., and Tezuka, Y. CYP3A4 and CYP2D6 inhibitory activities of Indonesian medicinal plants. Phytomedicine. 2006;13(1-2):67-73. PubMed
  15. Mujumdar, A. M., Dhuley, J. N., Deshmukh, V. K., Raman, P. H., Thorat, S. L., and Naik, S. R. Effect of piperine on pentobarbitone induced hypnosis in rats. Indian J Exp.Biol. 1990;28(5):486-487.
  16. Panda, S. and Kar, A. Piperine lowers the serum concentrations of thyroid hormones, glucose and hepatic 5'D activity in adult male mice. Horm.Metab Res. 2003;35(9):523-526. PubMed
  17. Lawless, H. and Stevens, D. A. Effects of oral chemical irritation on taste. Physiol Behav. 1984;32(6):995-998. PubMed
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Ecklonia Cava 1 reference
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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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