Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Androdiol Ingredients & Drug Interactions

by Hi-Tech Pharmaceuticals

Androdiol label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Androdiol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Androdiol is a dietary supplement by Hi-Tech Pharmaceuticals with 2 active ingredients. Its ingredients are commonly taken for muscle building, strength and athletic performance, boosting testosterone.Based on those ingredients, 8 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 4-Androstene-3b-ol, 17-one Decanoate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Androdiol by Hi-Tech Pharmaceuticals

Ask about any prescription or over-the-counter medication and we check it for interactions with Androdiol by Hi-Tech Pharmaceuticals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Androdiol by Hi-Tech Pharmaceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Androdiol contains 2 active ingredients. The main one, 4-Androstene-3b-ol, 17-one Decanoate, is a prohormone—a compound your body is supposed to convert into testosterone and related androgens.

The other active ingredient is 5a-Hydroxy Laxogenin Acetate, which we don't have detailed information on. The product has no inactive fillers or other ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: muscle building and testosterone support.
  • We looked for evidence on: strength, athletic performance, lean muscle gain.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We don't hold effectiveness ratings for either ingredient in Androdiol, so the evidence for whether it actually works as intended isn't established in our data.

The evidence, ingredient by ingredient 4-androsterone

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Prohormones like the ones in this product can disrupt your hormone balance, put stress on your liver, and change your cholesterol levels—and how safe they really are hasn't been well studied. Do not use during pregnancy; androgenic hormones can harm a developing baby.

Breastfeeding isn't safe either; we don't know how these hormonal effects would reach a nursing infant or what they might do. There's concern that 4-androsterone could theoretically cause serious side effects similar to anabolic steroids, including stroke, kidney failure, and liver injury, though specific adverse effect data is limited.

Side effects, ingredient by ingredient 4-androsterone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — 4-androsterone.
  • The most serious interaction on file is rated Moderate.
  • For scale: 8 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take testosterone medications or products, check with your pharmacist before using Androdiol—the combination could raise levels dangerously high and strain your cardiovascular system, kidneys, and liver.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Androdiol is a prohormone product meant to boost testosterone, but effectiveness data isn't available. If you take testosterone or are on hormone-related medications, this product carries a Moderate interaction risk.

Anyone pregnant or breastfeeding should not use it. Talk to your pharmacist before starting, especially if you have liver or kidney concerns or take any testosterone-related drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Androdiol, straight from the product label.

Brand Hi-Tech Pharmaceuticals
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 210056
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses Structure/Function
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Androdiol by Hi-Tech Pharmaceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
IngredientAmount% DV
5a-Hydroxy Laxogenin Acetate50 mg--
4-Androstene-3b-ol, 17-one Decanoate75 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Anabolic agent Test booster Minimal water retention Low estrogen conversion Lean muscle gains

Cyclosome Delivery

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Androdiol by Hi-Tech Pharmaceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Androdiol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Androdiol by Hi-Tech Pharmaceuticals

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

5a-Hydroxy Laxogenin Acetate

50 mg per serving

4-Androstene-3b-ol, 17-one Decanoate

Interacts with
8 drugs
75 mg per serving

4-Androsterone (sometimes called 4-DHEA) is a lab-made prohormone marketed to bodybuilders as a way to raise testosterone and build muscle, but human...

4-Androstene-3b-ol, 17-one Decanoate monograph & interactions
Interaction report

Androdiol by Hi-Tech Pharmaceuticals Drug Interactions

Want to check YOUR meds against Androdiol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
8Drugs
8 Moderate

Ingredients driving the most interactions

4-Androstene-3b-ol, 17-one Decanoate 8

Individual Drug Interactions

The ingredients in Androdiol interact with 8 drugs. Click any drug to see the details.

1 of the 2 ingredients in Androdiol interact with drugs. Each result below shows which ingredient is responsible. 4-Androstene-3b-ol, 17-one Decanoate

Each ingredient & the kinds of drugs it affects

For each ingredient in Androdiol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

4-Androstene-3b-ol, 17-one Decanoate1 drug type · 8 drugs

Testosterone

4-Androsterone is purportedly converted to testosterone and other androgens upon ingestion. Theoretically, taking 4-androsterone with testosterone may increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.

Likelihood Possible Evidence D
4-Androstene-3b-ol, 17-one Decanoate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Androdiol, from the product label.

Hi-Tech Pharmaceuticals

See all Hi-Tech Pharmaceuticals products
Name
Hi-Tech Pharmaceuticals
Pharmacist Counseling Corner

Androdiol by Hi-Tech Pharmaceuticals: Common Questions

Does Androdiol by Hi-Tech Pharmaceuticals interact with any medications?
Yes. Based on its ingredients, Androdiol has a known interaction with 8 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Androdiol contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Androdiol if I'm on testosterone therapy?
No—combining them is documented as a Moderate interaction risk. Taking both could increase testosterone to unsafe levels and cause mood changes, heart problems, or kidney and liver strain. Talk to your doctor or pharmacist before adding this product.
Is Androdiol safe during pregnancy?
No. Androgenic hormones can harm a developing baby, so the safety data advises against use during pregnancy. If you're planning to get pregnant or think you might be, don't use this product.
Is it safe to take while breastfeeding?
No. We don't know how the hormonal effects reach a nursing infant or what damage they might cause, and the safety data advises against it. Avoid this product while breastfeeding.
What does 4-Androstene-3b-ol, 17-one Decanoate do?
It's a prohormone meant to convert into testosterone and related androgens in your body. That's the theory—we don't have solid effectiveness data confirming it actually works that way.
What are the possible side effects?
Specific side effect data is limited, but because 4-androsterone is thought to convert to anabolic compounds, there's concern it could cause serious steroid-like effects: stroke, kidney failure, and liver injury. More broadly, prohormones can disrupt hormones, strain the liver, and change cholesterol.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Androdiol label
Go deeper

The Full Monographs Behind Androdiol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

4-androsterone

Interacts with 8 drugs

4-Androsterone (sometimes called 4-DHEA) is a lab-made prohormone marketed to bodybuilders as a way to raise testosterone and build muscle, but human studies are very limited and it carries...

Read the full 4-androsterone monograph →
Sources

Sources & How We Checked

Androdiol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

4-androsterone 3 references
  1. Anabolic Steroids and Other Appearance and Performance Enhancing Drugs (APEDs) — NIH National Institute on Drug Abuse Source
  2. Dietary Supplements for Exercise and Athletic Performance — NIH Office of Dietary Supplements Source
  3. DHEA — MedlinePlus Source

See these in context on the 4-androsterone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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