Major interaction on record — check this product against your medications before combining. Based on 6 of 21 ingredients. Check your meds →
Dietary supplement

Anavar Ingredients & Drug Interactions

by Hi-Tech Pharmaceuticals

Anavar label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Anavar against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Anavar is a dietary supplement by Hi-Tech Pharmaceuticals with 21 active ingredients. Its ingredients are commonly taken for improving high-intensity exercise performance, building muscle strength and size, sports and athletic training.Based on those ingredients, 1,027 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Dehydroepiandrosterone Acetate, L-Arginine Hydrochloride, Adenosine Triphosphate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Anavar by Hi-Tech Pharmaceuticals

Ask about any prescription or over-the-counter medication and we check it for interactions with Anavar by Hi-Tech Pharmaceuticals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Anavar by Hi-Tech Pharmaceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 21 active ingredients.
  • “Proprietary Blend with Extend-Rx Technology” is a proprietary blend — the label gives one combined amount (1,900 mg) without saying how much of each component you get.

Anavar contains 21 ingredients. The active components include two forms of creatine (creatine HCl and creatine nitrate) for muscle strength and athletic performance, L-arginine hydrochloride for blood vessel function, inosine ethyl ester, and adenosine triphosphate.

The product also contains four DHEA variants (dehydroepiandrosterone acetate, cypionate, propionate, and enanthate), 4-androstenolone, and plant-derived compounds including quebracho blanco HCl. Several other active ingredients—including 25-R-spirostan-5a-diol-6-one-3-one, 5a hydroxy laxogenin acetate, 6-keto diosgenin acetate, 20-hydroxyecdysone decanoate, and 1-androstenolone—are included in a proprietary blend with Extend-Rx technology.

The product contains no listed inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: increases strength, lean muscle mass, and size.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Muscle strength, Physical performance, Sarcopenia, Muscle breakdown — and 4 related terms.
  • The strongest evidence on file: Creatine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Creatine is rated "Possibly Effective" for Muscle strength, Sarcopenia.
  • Also on file: Adenosine is rated "Possibly Effective" for Cachexia.

Creatine (both HCl and nitrate forms) is possibly effective for muscle strength, athletic performance, sarcopenia (age-related muscle loss), and cerebral creatine deficiency syndromes, but possibly ineffective for Huntington disease and osteopenia. The DHEA variants are likely effective for vaginal atrophy and possibly effective for infertility, aging skin, and depression.

Inosine ethyl ester and adenosine triphosphate lack reliable evidence in our data—the research on their effectiveness for conditions like ALS, athletic performance, or cancer is insufficient to rate. For quebracho blanco HCl, we hold no effectiveness data.

The data we have does not establish the effectiveness of 6,7 dihydroxybergamottin, naringen, or the other proprietary blend ingredients.

The evidence, ingredient by ingredient Creatine L-arginine Inosine Adenosine Dhea Quebracho Blanco

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Creatine is generally well tolerated in healthy adults but should be used cautiously by those with kidney issues. Common side effects include dehydration, diarrhea, stomach upset, muscle cramps, and water retention.

Rare serious effects reported in case studies include kidney damage and blood clots, though large studies haven't confirmed these. L-arginine is often well tolerated short-term but can lower blood pressure and requires medical supervision for self-treatment.

Common side effects include stomach pain, bloating, nausea, diarrhea, headache, and insomnia. Inosine raises uric acid levels, which is concerning if you have gout or kidney problems; common side effects include kidney stones and high uric acid.

Adenosine's oral supplement form has limited safety data; the prescription injectable form carries serious cardiovascular risks. DHEA forms are generally well tolerated short-term but hormonal side effects include acne (especially in women), headache, insomnia, mood changes, and in women, voice deepening and facial hair growth.

Long-term use raises theoretical cancer concerns. Quebracho blanco has limited human safety data; it may cause headache, dizziness, drowsiness, and at high doses nausea and vomiting.

Side effects, ingredient by ingredient Creatine L-arginine Inosine Adenosine Dhea Quebracho Blanco

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 6 matched ingredients can interact with medications — Dhea, Inosine, L-arginine, Adenosine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,028 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check with your pharmacist if you're on a beta-blocker (like metoprolol), blood thinner (warfarin, apixaban, aspirin), blood pressure medication (lisinopril, losartan, diltiazem), diabetes medication, antidepressant, cancer hormone therapy (tamoxifen, aromatase inhibitor, fulvestrant), carbamazepine (Tegretol), triazolam (Halcion), sildenafil (Viagra), gout medication, or methylxanthines (caffeine supplements, theophylline). No interactions are documented for the creatine or quebracho blanco components we could fully check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a multi-ingredient athletic and hormonal supplement with creatine, DHEA variants, and L-arginine. If you're on any blood pressure medication, blood thinner, diabetes drug, antidepressant, or cancer hormone therapy, or if you have kidney or gout issues, talk to your pharmacist or doctor before starting—the interaction list is extensive.

Women should know that DHEA can cause masculinizing effects, and long-term hormone use needs medical oversight. Creatine alone is generally tolerated, but the DHEA and L-arginine components require caution.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 11 of 21 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Anavar, straight from the product label.

Brand Hi-Tech Pharmaceuticals
Net contents 180 ct
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 242302
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Anavar by Hi-Tech Pharmaceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Tablet(s)
Maximum serving Sizes:
3 Tablet(s)
Servings per container
60
IngredientAmount% DV
Creatine HCl0 NP--
6,7 Dihydroxybergamottin0 NP--
L-Arginine Hydrochloride0 NP--
Naringen0 NP--
Proprietary Blend with Extend-Rx Technology1900 mg--
S-(2 Boronoethyl) L-Cysteine HCl0 NP--
2-(S)-Amino-6-Boronohexanoic Acid0 NP--
Creatine Nitrate0 NP--
Inosine Ethyl Ester0 NP--
Adenosine Triphosphate0 NP--
25-R-Spirostan-5A-Diol-6-One-3-One0 NP--
Dehydroepiandrosterone Acetate0 NP--
Dehydroepiandrosterone Cypionate0 NP--
Dehydroepiandrosterone Propionate0 NP--
Dehydroepiandrosterone Enanthate0 NP--
5a Hydroxy Laxogenin Acetate0 NP--
6-Keto Diosgenin Acetate0 NP--
20-Hydroxyecdysone Decanoate0 NP--
1-Androstenolone0 NP--
4-Androstenolone0 NP--
Epiandrostenolone0 NP--
Quebracho Blanco HCl0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Controlled-release natural steroidal anabolic agent Increases strength by stimulating adenosine triphosphate Elevates testosterone levels throughout the day Increases strength, lean muscle mass, and size

FDA Statement of Identity

Dietary Supplement

Formula

633 mg

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Anavar by Hi-Tech Pharmaceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Anavar label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Anavar by Hi-Tech Pharmaceuticals

These are the 21 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend with Extend-Rx Technology

1900 mg per serving
Interaction report

Anavar by Hi-Tech Pharmaceuticals Drug Interactions

Want to check YOUR meds against Anavar?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,027Drugs
2 Major 1,002 Moderate 23 Minor

Ingredients driving the most interactions

Dehydroepiandrosterone Acetate 776
L-Arginine Hydrochloride 403
Adenosine Triphosphate 47
Inosine Ethyl Ester 9

Individual Drug Interactions

The ingredients in Anavar interact with 1,027 drugs. Click any drug to see the details.

4 of the 21 ingredients in Anavar interact with drugs. Each result below shows which ingredient is responsible. Dehydroepiandrosterone Acetate L-Arginine Hydrochloride Adenosine Triphosphate Inosine Ethyl Ester

Each ingredient & the kinds of drugs it affects

For each ingredient in Anavar with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dehydroepiandrosterone Acetate10 drug types · 776 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Human and laboratory research show that DHEA and DHEA-S can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidepressant Drugs

Theoretically, DHEA might increase the risk of psychiatric adverse events when used with antidepressants.
In a human case report, the use of a selective serotonin reuptake inhibitor (SSRI) with DHEA caused a manic episode. Concern for this interaction may be greater in younger individuals with higher baseline DHEA levels.

Likelihood Possible Evidence D
Aromatase Inhibitors

Theoretically, DHEA might interfere with the clinical effects of aromatase inhibitors.
DHEA is a potent estrogen agonist, which may antagonize the anti-estrogen activity of aromatase inhibitors.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Some preliminary evidence shows that DHEA may inhibit CYP3A4; however, the clinical significance of this potential interaction is not known.

Likelihood Possible Evidence D
Fulvestrant (Faslodex)

Theoretically, DHEA might interfere with the anti-estrogen effects of fulvestrant.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist action of fulvestrant in estrogen-receptor positive cancer cells.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, DHEA might interfere with the anti-estrogen effects of tamoxifen.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist activity of tamoxifen in estrogen-receptor positive cancer cells.

Likelihood Possible Evidence D
Triazolam (Halcion)

DHEA can increase blood levels of triazolam.
Administration of DHEA 200 mg daily for two weeks was shown to inhibit the cytochrome P450 3A4 (CYP3A4) metabolism of triazolam. This inhibition appears to be due to DHEA-S, rather than DHEA.

Likelihood Probable Evidence D
Tuberculosis Vaccine

DHEA might reduce the effectiveness of the tuberculosis vaccine.
Animal research shows that high doses of DHEA can reduce the efficacy of the Bacillus Calmette-Guérin (BCG) tuberculosis vaccine.

Likelihood Possible Evidence D
Estrogens

Theoretically, DHEA might increase the effects and adverse effects of estrogen therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. Also, in clinical research, estrogen-progestin oral contraceptives and conjugated estrogens reduce blood levels of DHEA and DHEA-S. The clinical significance of these findings is unclear.

Likelihood Possible Evidence D
Testosterone

Theoretically, DHEA might increase the effects and side effects of testosterone therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. The clinical significance of these findings is unclear.

Likelihood Possible Evidence D
Dehydroepiandrosterone Acetate full monograph & interactions

L-Arginine Hydrochloride9 drug types · 403 drugs

Ace Inhibitors (Aceis)

Theoretically, concomitant use of L-arginine and ACE inhibitors may increase the risk for hypotension and hyperkalemia.
Combining L-arginine with some antihypertensive drugs, especially ACE inhibitors, seems to have additive vasodilating and blood pressure-lowering effects. Furthermore, ACE inhibitors can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ACE inhibitors with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, concomitant use of L-arginine and ARBs may increase the risk of hypotension and hyperkalemia.
L-arginine increases nitric oxide, which causes vasodilation. Combining L-arginine with ARBs seems to increase L-arginine-induced vasodilation. Furthermore, ARBs can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ARBs with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of bleeding.
Preliminary research suggests that L-arginine infusions reduce platelet aggregation in humans. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of L-arginine might have additive effects with antidiabetes drugs.
Preliminary clinical research shows that L-arginine decreases blood glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.
L-arginine increases nitric oxide, which causes vasodilation. Clinical evidence shows that L-arginine can reduce blood pressure in some individuals with hypertension. Furthermore, combining L-arginine with some antihypertensive drugs seems to have additive vasodilating and blood pressure-lowering effects.

Likelihood Probable Evidence D
Isoproterenol (Isuprel)

Theoretically, concurrent use of isoproterenol and L-arginine might result in additive effects and hypotension.
Preliminary clinical evidence suggests that L-arginine enhances isoproterenol-induced vasodilation in patients with essential hypertension or a family history of essential hypertension.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically concomitant use of potassium-sparing diuretics with L-arginine may increases the risk of hyperkalemia.
Potassium-sparing diuretics can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and L-arginine might increase the risk for hypotension.
In vivo, concurrent use of L-arginine and sildenafil has resulted in increased vasodilation. Theoretically, concurrent use might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
Testosterone

Theoretically, concomitant use of L-arginine and testosterone might have additive effects.
In clinical research, L-arginine increases the level of testosterone in male patients with erectile dysfunction. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
L-Arginine Hydrochloride full monograph & interactions

Adenosine Triphosphate3 drug types · 47 drugs

Dipyridamole (Persantine)

Dipyridamole can increase the therapeutic and toxic effects of adenosine.
Dipyridamole decreases the metabolism of adenosine. Intravenous infusion of adenosine in patients who are taking dipyridamole can cause dizziness, bradycardia, and syncope. Dipyridamole should be discontinued for several days prior to a cardiac stress test using adenosine.

Likelihood Likely Evidence D
Carbamazepine (Tegretol)

Carbamazepine might increase the risk of heart block when used concomitantly with adenosine.
Carbamazepine and adenosine can both cause heart block. Giving them concurrently might produce an additive effect.

Likelihood Possible Evidence D
Methylxanthines

Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
The methylxanthines, aminophylline, caffeine, and theophylline, can block the effects of adenosine by acting as competitive antagonists at adenosine cell surface receptors. It is recommended that methylxanthines be avoided for 24 hours prior to cardiac stress tests.

Likelihood Possible Evidence D
Adenosine Triphosphate full monograph & interactions

Inosine Ethyl Ester1 drug type · 9 drugs

Antigout Drugs

Inosine might reduce the effects of antigout medications.
Inosine increases uric acid levels in the serum and urine, potentially resulting in hyperuricemia and reducing the effects of medications used for the prevention and treatment of gout.

Likelihood Possible Evidence D
Inosine Ethyl Ester full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Anavar, from the product label.

Hi-Tech Pharmaceuticals

See all Hi-Tech Pharmaceuticals products
Name
Hi-Tech Pharmaceuticals
Pharmacist Counseling Corner

Anavar by Hi-Tech Pharmaceuticals: Common Questions

Does Anavar by Hi-Tech Pharmaceuticals interact with any medications?
Yes. Based on its ingredients, Anavar has a known interaction with 1,027 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Anavar contains 21 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have high blood pressure?
L-arginine in this product can lower blood pressure, and combining it with blood pressure medications may cause a dangerous drop. Talk to your doctor or pharmacist before using this product if you're on any blood pressure drug—they'll need to check your specific medication against the ingredients.
Is it safe during pregnancy?
No. Both creatine forms and all DHEA variants in this product advise against use during pregnancy because safety hasn't been established or because DHEA affects hormone levels. Talk to your doctor if you're pregnant or planning to become pregnant.
What about nursing?
Safety data for nursing mothers isn't available for the creatine, DHEA variants, inosine, adenosine, or quebracho blanco in this product. Avoid use while breastfeeding unless your doctor advises otherwise.
Does this really help with muscle and strength?
Creatine—one of the main active ingredients—is possibly effective for muscle strength and athletic performance. The DHEA forms lack strong evidence for muscle building in our data. Other ingredients lack sufficient evidence to rate.
What are the most common side effects?
From creatine: dehydration, diarrhea, stomach upset, muscle cramps, and water retention. From L-arginine: stomach pain, bloating, nausea, and headache. From DHEA: acne, headache, insomnia, and mood changes. Women may experience voice changes and increased facial hair.
Can I take this if I have kidney disease?
Both creatine forms advise caution in people with kidney issues. Inosine can raise uric acid and cause kidney stones, especially if combined with calcium supplements. Talk to your doctor before using this product if you have kidney problems.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Anavar label
Go deeper

The Full Monographs Behind Anavar’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Creatine

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...

Read the full Creatine monograph → Herb & supplement monograph

L-arginine

Interacts with 403 drugs

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for blood pressure, erectile dysfunction, and...

Read the full L-arginine monograph → Herb & supplement monograph

Inosine

Interacts with 9 drugs

Inosine is a nucleoside (a building block of DNA and RNA) that the body makes on its own and is also sold as a supplement, mostly marketed for athletic performance. Solid evidence that it bo...

Read the full Inosine monograph → Herb & supplement monograph

Adenosine

Interacts with 47 drugs

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat certain fast heart rhythms. As an over-t...

Read the full Adenosine monograph → Herb & supplement monograph

Dhea

Interacts with 776 drugs

DHEA is a natural hormone that the body makes and that declines with age, and it is sold as a supplement claiming many benefits. The evidence is mixed and limited for most uses, and because...

Read the full Dhea monograph → Herb & supplement monograph

Quebracho Blanco

Quebracho Blanco is the bark of a South American tree traditionally used for breathing problems and coughs, but high-quality human studies are lacking. It contains alkaloids that may affect...

Read the full Quebracho Blanco monograph →
Sources

Sources & How We Checked

Anavar's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 268 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Creatine 86 references
  1. Koshy KM, Griswold E, Schneeberger EE. Interstitial nephritis in a patient taking creatine. N Engl J Med 1999;340:814-5. PubMed
  2. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  3. Greenhaff P. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;352:233-4. PubMed
  4. Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training (abstract). J Appl Physiol 1997;83:2055-63. PubMed
  5. Hultman E, Soderlund K, Timmons JA, et al. Muscle creatine loading in men. J Appl Physiol 1996;81:232-7. PubMed
  6. Pritchard NR, Kalra PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252-3. PubMed
  7. Poortmans JR, Auquier H, Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men (abstract). Eur J Appl Physiol Occup Physiol 1997;76:566-7. PubMed
  8. Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108-10. PubMed
  9. Mihic S, MacDonald JR, McKenzie S, Tarnopolsky MA. Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. Med Sci Sports Exerc 2000;32:291-6. PubMed
  10. Rawson ES, Wehnert ML, Clarkson PM. Effects of 30 days of creatine ingestion in older men. Eur J Appl Physiol Occup Physiol 1999;80:139-44. PubMed
  11. Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci (Colch) 1996;91:113-8. PubMed
  12. Juhn MS. Oral creatine supplementation. Separating fact from hype. Phys Sportsmed 1999;27:47-50,53-54,56,61,89. PubMed
  13. Juhn MS, O'Kane JW, Vinci DM. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am Diet Assoc 1999;99:593-5.
  14. Green AL, Hultman E, Macdonald IA, et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am J Physiol 1996;271:E821-6. PubMed
  15. Balsom PD, Soderlund K, Sjodin B, Ekblom B. Skeletal muscle metabolism during short duration high-intensity exercise: influence of creatine supplementation. Acta Physiol Scand 1995;154:303-10. PubMed
  16. Snow RJ, McKenna MJ, Selig SE, et al. Effect of creatine supplementation on sprint exercise performance and muscle metabolism. (abstract) J Appl Physiol 1998;84:1667-73. PubMed
  17. McNaughton LR, Dalton B, Tarr J. The effects of creatine supplementation on high-intensity exercise performance in elite performers. (abstract) Eur J Appl Physiol Occup Physiol 1998;78:236-40. PubMed
  18. Groeneveld GJ, Veldink JH, van der Tweel I, et al. A randomized sequential trial of creatine in amyotrophic lateral sclerosis. Ann Neurol 2003;53:437-45. . PubMed
  19. Robinson SJ. Acute quadriceps compartment syndrome and rhabdomyolysis in a weight lifter using high-dose creatine supplementation. J Am Board Fam Pract 2000;13:134-7. PubMed
  20. Kammer RT. Lone atrial fibrillation associated with creatine monohydrate supplementation. Pharmacotherapy 2005;25:762-4. PubMed
  21. Gualano B, Ugrinowitsch C, Novaes RB, et al. Effects of creatine supplementation on renal function: a randomized, double-blind, placebo-controlled clinical trial. Eur J Appl Physiol 2008;103:33-40. PubMed
  22. Pfeffer, G., Majamaa, K., Turnbull, D. M., Thorburn, D., and Chinnery, P. F. Treatment for mitochondrial disorders. Cochrane Database.Syst.Rev. 2012;4:CD004426. PubMed
  23. Boos, C. J., White, S. H., Bland, S. A., and McAllister, P. D. Dietary supplements and military operations: caution is advised. J R.Army Med Corps 2010;156(1):41-43. PubMed
  24. Kreider, R. B. Dietary supplements and the promotion of muscle growth with resistance exercise. Sports Med 1999;27(2):97-110. PubMed
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See these in context on the Creatine monograph →

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See these in context on the Dhea monograph →

Quebracho Blanco 1 reference
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Quebracho Blanco monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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