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Dietary supplement

Artemisinin Ingredients & Drug Interactions

by HUMANX

Artemisinin label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Artemisinin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Artemisinin is a dietary supplement by HUMANX with 1 active ingredient. Its ingredients are commonly taken for malaria (traditional), fever, inflammation.Based on those ingredients, 889 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Artemisinin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Artemisinin by HUMANX

Ask about any prescription or over-the-counter medication and we check it for interactions with Artemisinin by HUMANX — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Artemisinin by HUMANX

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: artemisinin, the compound derived from Sweet Annie. Artemisinin has been studied for hay fever, malaria, fatty liver disease, and osteoarthritis.

The capsule itself is made from methylcellulose, an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports healthy gut and digestive wellness.
  • We looked for evidence on: Digestive health, Gut health, General wellness.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Artemisinin is possibly effective for allergic rhinitis (hay fever) based on the evidence we hold. For nonalcoholic fatty liver disease, malaria, and osteoarthritis, the evidence is insufficient to rate — meaning we don't yet know whether it works for these uses.

If you're taking it for one of those uncertain uses, talk with your doctor or pharmacist about whether there's clinical support for your situation.

The evidence, ingredient by ingredient Sweet Annie

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Artemisinin is generally well tolerated when taken by mouth in the short term. The most common side effects are nausea and vomiting.

Rarely, hepatotoxicity (liver damage) has been reported — one documented case involved a patient who developed hepatitis after taking artemisinin 200 mg three times daily for 10 days; symptoms resolved after stopping. A mild allergic reaction with rash and cough has also been reported once.

The safety data advises against artemisinin during pregnancy because of possible harm to a developing baby. There isn't enough safety information to recommend it while breastfeeding — talk with your doctor or pharmacist for personalized advice.

Quality and doses vary widely across products, so artemisinin should not replace proven medical treatments.

Side effects, ingredient by ingredient Sweet Annie

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sweet Annie.
  • The most serious interaction on file is rated Moderate.
  • For scale: 890 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take artemisinin, double-check any medications that stress the liver (hepatotoxic drugs) — the risk is moderate. Also check drugs metabolized by the liver enzymes CYP3A4 and CYP2B6, since artemisinin may alter their blood levels and effects — also rated moderate.

Use the medication search tool on this page to verify your specific prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Artemisinin may be worth considering if you have hay fever and are interested in herbal options, but it interacts with a substantial number of medications and can affect how your liver processes drugs. If you take any prescription medications, check them against this product's interactions before you start — especially if you take drugs that are hard on the liver or depend on liver enzymes to work.

Talk to your pharmacist, particularly if you're pregnant, breastfeeding, or have liver concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 19, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Artemisinin, straight from the product label.

Brand HUMANX
Barcode (UPC) X002LIKHY9
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD May 19, 2022
DSLD ID 267995
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Artemisinin by HUMANX, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
X002LIKHY9
IngredientAmount% DV
Artemisinin450 mg--

Other ingredients: Methylcellulose Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Artemisinin supports a healthy gut for optimal digestive and general health.

Artemisinin 450 milligrams per serving

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take three capsules per day with a glass of water, or as recommended by your healthcare professional.

Precautions

Caution: Keep out of reach of children and pets.

Consult with a qualified healthcare professional prior to using this product. Do not exceed recommended daily intake. Do not use if safety seal is damaged or missing.

Storage

Store at room temperature, in a dry place. Protect product from excessive heat, freezing, humidity, and light.

General Statements

100% Refund Guaranteed Refund Guarantee We offer a full refund on the purchase price of your order (minus return costs) within 30 days of purchase. Restrictions apply. Please visit shophumanx.com for full details.

Formulation

Supports healthy digestion & wellness

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Artemisinin by HUMANX label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Artemisinin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Artemisinin by HUMANX

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Artemisinin

Interacts with
889 drugs
450 mg per serving Form: Wormwood

Sweet Annie (Artemisia annua) is the source of artemisinin, a compound used in prescription antimalarial drugs. While the purified drug is well studie...

Artemisinin monograph & interactions

Other (inactive) ingredients: Methylcellulose Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Artemisinin by HUMANX Drug Interactions

Want to check YOUR meds against Artemisinin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
889Drugs
889 Moderate

Ingredients driving the most interactions

Artemisinin 889

Individual Drug Interactions

The ingredients in Artemisinin interact with 889 drugs. Click any drug to see the details.

1 of the 1 ingredient in Artemisinin interact with drugs. Each result below shows which ingredient is responsible. Artemisinin

Each ingredient & the kinds of drugs it affects

For each ingredient in Artemisinin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Artemisinin3 drug types · 889 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP2B6.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP2B6, possibly increasing CYP2B6 activity by 1.6-fold. However, Sweet Annie extract seems to inhibit the activity of CYP2B6 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP2B6 substrates.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Sweet Annie may alter plasma levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that the Sweet Annie constituent artemisinin induces CYP3A4, possibly increasing CYP3A4 activity by 1.9-fold. However, Sweet Annie extract seems to inhibit the activity of CYP3A4 in vitro, suggesting that other constituents of Sweet Annie play a role in its effects on the overall activity of this enzyme. More information is needed to determine whether taking Sweet Annie extract affects the metabolism of CYP3A4 substrates.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use might have additive adverse hepatotoxic effects.
There is some concern that Sweet Annie can adversely affect the liver.

Likelihood Possible Evidence D
Artemisinin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Artemisinin, from the product label.

HUMANX

See all HUMANX products
Name
Illumina LLC
Street Address
302 Washington St #151
City
San Diego
State
CA
ZipCode
92103
Web Address
www.shophumanx.com
Pharmacist Counseling Corner

Artemisinin by HUMANX: Common Questions

Does Artemisinin by HUMANX interact with any medications?
Yes. Based on its ingredients, Artemisinin has a known interaction with 889 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Artemisinin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take artemisinin if I'm pregnant or breastfeeding?
The safety data advises against artemisinin during pregnancy because of possible harm to your baby. While breastfeeding, there isn't enough safety information to know either way — talk with your doctor or pharmacist for personalized advice.
What's the most common side effect?
Nausea and vomiting are the most common side effects when taken by mouth. They're generally mild, but if they persist, let your pharmacist know.
Does artemisinin work for malaria or fatty liver disease?
The evidence we hold is insufficient to rate artemisinin for either condition. While it's been studied, we don't yet know if it's reliably effective. Talk with your doctor if you're considering it for these uses.
Is artemisinin safe to take long-term?
It's generally used short-term, and quality and dose vary widely across products. It shouldn't replace proven treatments. Check with your pharmacist about how long you should take it.
Can artemisinin harm my liver?
There's documented concern that artemisinin may adversely affect the liver. One rare case of hepatitis has been reported after taking high doses for 10 days. If you have liver disease or take medications hard on the liver, talk with your pharmacist first.
What's in this capsule besides artemisinin?
The capsule itself is made from methylcellulose, an inactive ingredient. There are no other added ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Artemisinin is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Artemisinin label
Go deeper

The Full Monographs Behind Artemisinin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sweet Annie

Interacts with 889 drugs

Sweet Annie (Artemisia annua) is the source of artemisinin, a compound used in prescription antimalarial drugs. While the purified drug is well studied for malaria, the herb itself as a supp...

Read the full Sweet Annie monograph →
Sources

Sources & How We Checked

Artemisinin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sweet Annie 11 references
  1. Mueller MS, Karhagomba IB, Hirt HM, Wemakor E. The potential of Artemisia annua L. as a locally produced remedy for malaria in the tropics: agricultural, chemical and clinical aspects. J Ethnopharmacol 2000;73:487-93. PubMed
  2. Rath K, Taxis K, Walz G, et al. Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood). Am J Trop Med Hyg 2004;70:128-32. DOI
  3. Centers for Disease Control and Prevention (CDC). Hepatitis temporally associated with an herbal supplement containing artemisinin-Washington, 2008. MMWR Morb Mortal Wkly Rep 2009;58:854-8.
  4. Xing J, Kirby BJ, Whittington D, et al. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes. Drug Metabl Dispos 2012;40(9):1757-64. PubMed
  5. Savage RL, Hill GR, Barnes J, Kenyon SH, Tatley MV. Suspected hepatotoxicity with a supercritical carbon dioxide extract of Artemisia annua in grapeseed oil used in New Zealand. Front Pharmacol. 2019;10:1448. PubMed
  6. Ruperti-Repilado FJ, Haefliger S, Rehm S, et al. Danger of herbal tea: a case of acute cholestatic hepatitis due to Artemisia annua tea. Front Med (Lausanne). 2019;6:221. PubMed
  7. Yang J, Shen Z, Liu L, et al. Clinical efficacy and safety of Artesimia annua-Sublingual immunotherapy in seasonal allergic rhinitis patients based on different intervention time. Int Arch Allergy Immunol 2022;183(8):852-859.
  8. Kane NF, Kiani BH, Desrosiers MR, Towler MJ, Weathers PJ. Artemisia extracts differ from artemisinin effects on human hepatic CYP450s 2B6 and 3A4 in vitro. J Ethnopharmacol 2022. DOI
  9. Feng Y, Cao Y, Liu Y, et al. Clinical efficacy and safety of coseasonal initiation of Artemisia annua sublingual immunotherapy on patients with Artemisia-induced rhinoconjunctivitis. Am J Otolaryngol 2023;44(5):103942. PubMed
  10. Yang J, Wang W, Shen Z, et al. Efficacy and safety of Artemisia annua sublingual immunotherapy in patients with seasonal allergic rhinoconjunctivitis over two pollen seasons. Eur Arch Otorhinolaryngol. 2023;280(11):4939-4947. PubMed
  11. Shen Z, Zhang P, Kang W, et al. Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals. Am J Otolaryngol 2023;44(6):104002. PubMed

See these in context on the Sweet Annie monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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