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Dietary supplement

Ashwagandha Gummies Ingredients & Drug Interactions

by Goli Nutrition

Gummy Or Jelly Category: Botanical With Nutrients
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Ashwagandha Gummies is a dietary supplement by Goli Nutrition with 3 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 1,397 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are KSM-66, Vitamin D2, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Ashwagandha Gummies by Goli Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Ashwagandha Gummies contains 3 active ingredients. Sodium is included in the formulation—a mineral essential in small amounts but one to watch if you're managing blood pressure or kidney health.

Vitamin D2 (also called ergocalciferol) supports bone health and calcium regulation, particularly for conditions like rickets and osteomalacia. KSM-66 is a standardized ashwagandha extract, an herb traditionally used to address stress, anxiety, and sleep.

The product also contains inactive ingredients like tapioca syrup, cane sugar, pectin, natural flavors, citric acid, and sunflower lecithin as binders and sweeteners in the gummy form.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: reduce stress and support memory concentration.
  • We looked for evidence on: Anxiety, Generalized anxiety disorder (GAD), Cognitive function, Age-related cognitive decline, Cognitive impairment, Fatigue — and 3 related terms.
  • The strongest evidence on file: Ashwagandha is rated "Possibly Effective" for Anxiety (Natural Medicines).
  • Also on file: Ashwagandha is rated "Possibly Effective" for Generalized anxiety disorder (GAD), Stress.
  • Also on file: Vitamin D is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline, Generalized anxiety disorder (GAD), Cognitive function, Cognitive impairment.

Vitamin D2 is well-established for treating certain bone and mineral disorders—it's rated Effective for familial hypophosphatemia, osteomalacia, renal osteodystrophy, rickets, and hypoparathyroidism. Ashwagandha (KSM-66) has preliminary support as Possibly Effective for insomnia, anxiety, stress, and generalized anxiety disorder, though the evidence is not as robust.

Sodium's effectiveness ratings in the data relate to cystic fibrosis (rated Likely Effective) and amphotericin B nephrotoxicity (Possibly Effective), which are medical conditions typically managed under a doctor's care, not common reasons someone would take a gummy supplement. The evidence for ashwagandha in bipolar disorder and other indications on this label is Insufficient Reliable Evidence To Rate.

The evidence, ingredient by ingredient Sodium Vitamin D Ashwagandha

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin D2 is well tolerated at recommended doses; serious adverse effects from toxicity are rare but can occur with very high doses over time and include symptoms of high calcium levels (hypercalcemia). Ashwagandha is generally well tolerated short-term in healthy adults, though quality and long-term safety data are limited.

The most common side effects from ashwagandha are mild—diarrhea, gastrointestinal upset, nausea, and vomiting—and are uncommon at typical doses. Rare serious adverse effects include acute hepatitis and liver failure; one case report also described intracranial bleeding possibly linked to ashwagandha use.

Sodium is fine in normal dietary amounts, but excess sodium is linked to high blood pressure and heart strain, and supplements should be avoided without medical guidance. Pregnancy and lactation: ashwagandha safety data suggests avoiding it during pregnancy (traditionally thought to risk miscarriage) and while breastfeeding due to insufficient information.

Vitamin D2 has no pregnancy or lactation data on file—talk to your doctor. Sodium is listed as Likely Safe in pregnancy but Possibly Unsafe in lactation.

Side effects, ingredient by ingredient Sodium Vitamin D Ashwagandha

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Vitamin D, Ashwagandha, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 1,398 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Ashwagandha Gummies, double-check any hepatotoxic (liver-damaging) drugs, blood pressure medications, blood sugar medications, benzodiazepines or other sedatives, thyroid hormones, immunosuppressants, and lithium. Also check corticosteroids, digoxin (Lanoxin), thiazide diuretics, and calcium-channel blockers like verapamil and diltiazem.

The sodium content matters if you take lithium or other sodium-sensitive medications. These are all Moderate interactions except for minor enzyme interactions.

No interactions are documented for the inactive ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're addressing vitamin D deficiency or bone health under medical supervision, the vitamin D2 in this product may help. The ashwagandha may support stress or sleep, though evidence is preliminary.

However, the sodium content and multiple drug interactions—especially with blood pressure, blood sugar, liver medications, sedatives, and thyroid drugs—mean you should check your exact medications with our tool before starting. Avoid this product during pregnancy or while breastfeeding.

Talk to your pharmacist before adding it to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ashwagandha Gummies, straight from the product label.

Brand Goli Nutrition
Barcode (UPC) 628176357942
Net contents 60 Gummy(ies)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 333642
Product type Botanical With Nutrients
Supplement form Gummy Or Jelly
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ashwagandha Gummies by Goli Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummy(ies)
Maximum serving Sizes:
2 Gummy(ies)
Servings per container
30
UPC/BARCODE
628176357942
IngredientAmount% DV
Calories25 Calorie(s)--
Total Carbohydrates6 Gram(s)2%
Sodium20 mg1%
Vitamin D225 mcg125%
Added Sugars4 Gram(s)8%
Total Sugars4 Gram(s)--
KSM-66300 mg--

Other ingredients: Tapioca Syrup, Cane Sugar, Water, Pectin, Natural Flavors, Malic Acid, Citric Acid, Sodium Citrate, Fruit and Vegetable Juice, Sunflower Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Relax. Restore. Unwind.

Made in a FDA registered and cGMP certified facility in the U.S.A.

Gluten-free Non-GMO

Plant-based

Vegan

Does not contain: yeast, wheat, eggs, gluten, soy, gelatin, peanuts, shellfish, dairy, synthetic colors, agave, and salicylates.

Formula

Our Goli Ashwa Gummies are made with clinically studied KSM-66 Ashwagandha. This root-only extract helps reduce cortisol levels to promote a healthy response to everyday stress and also supports certain aspects of memory and concentration, quality of sleep and more. Ashwagandha is an ancient herb that has been used for centuries for healthy living by helping to relax, restore and unwind.

Made with clinically studied KSM-66

OU Kosher Pareve

General Statements

Goli Nutrition is an inventive, people-focused nutrition company driven by the belief that happiness and wellness go hand in hand. We strive to provide innovative products, uniquely formulated with complementary ingredients all backed by science, in a delivery format that makes taking your daily supplements enjoyable!

Facebook / Instagram/ X @golinutrition #golinutrition

Seals/Symbols

Certified B Corporation

OU Kosher Pareve

Storage

Store in a cool, dry place after opening.

Precautions

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Warning: Consult a physician prior to use if pregnant or nursing, taking any medications or have any medical conditions.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 2 gummies, twice daily. Chew thoroughly.

See for yourself

Ashwagandha Gummies by Goli Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Ashwagandha Gummies by Goli Nutrition

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sodium

Interacts with
205 drugs
20 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Vitamin D2

Interacts with
715 drugs
25 mcg per serving Form: Ergocalciferol

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D2 monograph & interactions

KSM-66

Interacts with
1,372 drugs
300 mg per serving Form: Ashwagandha Root Extract

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...

KSM-66 monograph & interactions

Other (inactive) ingredients: Tapioca Syrup, Cane Sugar, Water, Pectin, Natural Flavors, Malic Acid, Citric Acid, Sodium Citrate, Fruit and Vegetable Juice, Sunflower Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ashwagandha Gummies by Goli Nutrition Drug Interactions

Want to check YOUR meds against Ashwagandha Gummies?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,397Drugs
948 Moderate 449 Minor

Ingredients driving the most interactions

KSM-66 1,372
Sodium 205

Each ingredient & the kinds of drugs it affects

For each ingredient in Ashwagandha Gummies with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

KSM-6610 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C

Vitamin D28 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
The maker

Brand information

Manufacturer and brand details for Ashwagandha Gummies, from the product label.

Goli Nutrition

See all Goli Nutrition products
Name
Goli Nutrition Inc.
City
West Hollywood
State
CA
ZipCode
90069
Phone Number
1-888-345-1452
Web Address
www.goli.com/ashwa
Pharmacist Counseling Corner

Ashwagandha Gummies by Goli Nutrition: Common Questions

Does Ashwagandha Gummies by Goli Nutrition interact with any medications?
Yes. Based on its ingredients, Ashwagandha Gummies has a known interaction with 1,397 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ashwagandha Gummies contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
No, you should avoid ashwagandha during pregnancy because it's traditionally been thought to carry a miscarriage risk. Vitamin D2 has no pregnancy safety data on file—talk to your doctor about whether it's right for you. Sodium is listed as Possibly Unsafe during lactation, so if you're breastfeeding, skip this product and speak with your pharmacist.
What is KSM-66, and what does it do?
KSM-66 is a standardized extract of ashwagandha, an herb used to support relaxation and stress relief. The research shows it's possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder, though the evidence is not as strong as for some other remedies.
Are there any side effects I should expect?
Most people tolerate ashwagandha well. The most common side effects are mild—diarrhea, nausea, or gastrointestinal upset—and they don't usually happen at typical doses. Rare serious side effects include liver damage, so stop and contact your doctor if you notice yellowing of the skin or eyes, dark urine, or unexplained bruising.
Does this product work for anxiety?
Ashwagandha in this product is rated Possibly Effective for anxiety and generalized anxiety disorder, meaning preliminary research supports its use but evidence is still developing. Results vary, and it's not a replacement for prescription medications if your doctor has recommended them.
Why is there sodium in a supplement gummy?
Sodium is added during manufacturing, likely as part of the formulation or flavor profile. If you're watching your sodium intake or taking blood pressure or kidney medications, this is worth discussing with your pharmacist, because even small extra sodium can add up.
Is vitamin D2 in this product safe to take daily?
Vitamin D2 is well tolerated at recommended doses. However, very high doses over time can cause toxicity with symptoms of high calcium levels. Stick to the dosage on the label and talk to your doctor if you're also taking other vitamin D supplements or medications that affect calcium, like thiazide diuretics or digoxin.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ashwagandha Gummies label
Sources

Sources & How We Checked

Ashwagandha Gummies's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 96 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
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Ashwagandha 32 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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