Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Apple Cider Vinegar Gummies Ingredients & Drug Interactions

by Goli Nutrition

Apple Cider Vinegar Gummies label
See full label image
Gummy Or Jelly Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Apple Cider Vinegar Gummies against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Apple Cider Vinegar Gummies is a dietary supplement by Goli Nutrition with 4 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 339 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sodium, Apple Cider Vinegar, Folic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Apple Cider Vinegar Gummies by Goli Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Apple Cider Vinegar Gummies by Goli Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Apple Cider Vinegar Gummies by Goli Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • “Folate” is listed as a grouped ingredient — the label gives one combined amount (400 mcg DFE) without saying how much of each component you get.

Goli Nutrition's Apple Cider Vinegar Gummies contain four active ingredients: folic acid (a B vitamin that helps prevent birth defects and treat deficiency), sodium (an electrolyte your body needs in small amounts), vitamin B12 (essential for nerve function and red blood cells), and apple cider vinegar (fermented apple juice with acetic acid). The gummies also contain inactive ingredients—cane sugar, tapioca syrup, pectin, citric acid, sodium citrate, natural flavors, malic acid, fruit and vegetable juice, and powders of beet and pomegranate—which serve as sweeteners, thickeners, and flavorings.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Incorporate apple cider vinegar into daily routine.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for this product's intended uses varies by ingredient. Folic acid is effective for folate deficiency and likely effective for preventing neural tube birth defects and reducing methotrexate toxicity; it's possibly effective for depression, phenytoin-induced gum overgrowth, and cognitive impairment.

Vitamin B12 is effective for B12 deficiency and cyanide poisoning, and possibly effective for canker sores and nerve pain. Apple cider vinegar, however, has insufficient evidence for acne, athletic performance, cognitive function, dental plaque, depression, or eczema—we don't know yet whether it works for these claims.

Sodium's effectiveness for cystic fibrosis is likely established, but evidence is insufficient for congestive heart failure or bipolar disorder.

The evidence, ingredient by ingredient Sodium Vitamin B12 Folic Acid Apple Cider Vinegar

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Folic acid is generally well tolerated at recommended doses in adults and is considered safe during pregnancy and breastfeeding at standard prenatal amounts. At doses of 5 mg daily or higher, some people report abdominal cramps, diarrhea, or rash; at 15 mg daily, bitter taste, confusion, hyperactivity, sleep problems, and irritability can occur.

Rare serious adverse effects (long-term use) include cancer, cardiovascular complications, liver injury, and seizures. Sodium is safe at normal dietary levels but poses risk with excess intake—high sodium is linked to high blood pressure, kidney disease, and heart strain, and may increase gastric cancer risk.

Apple cider vinegar in food amounts is well tolerated, but long-term use in larger doses can cause low potassium, bone loss, and kidney effects; topically it may cause chemical burns. Vitamin B12 is generally very safe with no upper limit, though allergic reactions and rare severe low potassium (with B12 correction of certain anemias) have been reported.

Folic acid use late in pregnancy has been associated with increased childhood asthma and respiratory infections in some population research, though early pregnancy or pre-pregnancy use has not.

Side effects, ingredient by ingredient Sodium Vitamin B12 Folic Acid Apple Cider Vinegar

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Apple Cider Vinegar, Vitamin B12, Folic Acid, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications; lithium.
  • For scale: 339 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take seizure medications (phenobarbital, phenytoin, primidone), cancer drugs (methotrexate, capecitabine, 5-fluorouracil), blood pressure medications, lithium, digoxin, diuretics, insulin, diabetes drugs, or corticosteroids. The sodium and apple cider vinegar in particular pose Moderate-severity risks with several of these, and folic acid can interfere with seizure control and cancer treatment efficacy.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be helpful if you're looking to supplement folic acid or vitamin B12, but the apple cider vinegar and sodium components carry documented interactions with common medications—especially seizure drugs, blood pressure drugs, diabetes drugs, lithium, and heart medications. Before you start, run your prescription list through our interaction checker on this page.

If you take seizure medications, cancer drugs, or manage blood pressure or electrolytes with medication, talk with your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Apple Cider Vinegar Gummies, straight from the product label.

Brand Goli Nutrition
Barcode (UPC) 627987249620
Net contents 60 Gummy(ies)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 331114
Product type Botanical With Nutrients
Supplement form Gummy Or Jelly
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Apple Cider Vinegar Gummies by Goli Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gummy(ies)
Maximum serving Sizes:
2 Gummy(ies)
Servings per container
30
UPC/BARCODE
627987249620
IngredientAmount% DV
Calories25 Calorie(s)--
Total Carbohydrates6 Gram(s)2%
Folic Acid240 mcg--
Sodium15 mg1%
Vitamin B122.4 mcg100%
Added Sugars4 Gram(s)8%
Total Sugars4 Gram(s)--
Folate400 mcg DFE100%
Apple Cider Vinegar1000 mg--

Other ingredients: Cane Sugar, Tapioca Syrup, Water, Pectin, Sodium Citrate, Natural Flavors, Malic Acid, Citric Acid, Fruit and Vegetable Juice, Beet, Powder, Pomegranate, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Goli Nutrition Taste the apple. Not the vinegar.

www.goli.com/patents

General Statements

Goli Nutrition is an inventive, people-focused nutrition company driven by the belief that happiness and wellness go hand in hand.

Health Simple.

Facebook / Instagram/ Twitter @golinutrition #golinutrition

Formula

Our goal was to create an easy and delicious way to incorporate Apple Cider Vinegar, plus added vitamins, into your daily routine.

World's First Apple Cider Vinegar Gummies

OU (Kosher) Pareve

Formulation

We are proud that our Goli Gummies are gluten-free, Non-GMO, gelatin-free and Vegan.

We are proud that our Goli Gummies are gluten-free, Non-GMO, gelatin-free and Vegan.

Made in a FDA registered and cGMP certified facility in the U.S.A.

Gluten-free Non-GMO Unfiltered Apple cider vinegar

Vegan

Does not contain: yeast, wheat, eggs, gluten, soy, gelatin, peanuts, shellfish, dairy, synthetic colors, agave, and salicylates.

Seals/Symbols

Certified B Corporation

OU (Kosher) Pareve

Storage

Store in a cool, dry place after opening.

Precautions

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Warning: Consult a physician prior to use if pregnant or nursing, taking any medications or have any medical conditions.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 1-2 gummies, 3 times daily. Chew thoroughly.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Apple Cider Vinegar Gummies by Goli Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Apple Cider Vinegar Gummies label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Apple Cider Vinegar Gummies by Goli Nutrition

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sodium

Interacts with
205 drugs
15 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Vitamin B12

Interacts with
20 drugs
2.4 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Folate

400 mcg DFE per serving Form: Folic Acid

Apple Cider Vinegar

Interacts with
162 drugs
1000 mg per serving Form: Acetic Acid

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...

Apple Cider Vinegar monograph & interactions

Other (inactive) ingredients: Cane Sugar, Tapioca Syrup, Water, Pectin, Sodium Citrate, Natural Flavors, Malic Acid, Citric Acid, Fruit and Vegetable Juice, Beet, Powder, Pomegranate, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Apple Cider Vinegar Gummies by Goli Nutrition Drug Interactions

Want to check YOUR meds against Apple Cider Vinegar Gummies?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
339Drugs
266 Moderate 73 Minor

Ingredients driving the most interactions

Sodium 205
Apple Cider Vinegar 162
Folic Acid 40
Vitamin B12 20

Individual Drug Interactions

The ingredients in Apple Cider Vinegar Gummies interact with 339 drugs. Click any drug to see the details.

4 of the 4 ingredients in Apple Cider Vinegar Gummies interact with drugs. Each result below shows which ingredient is responsible. Sodium Apple Cider Vinegar Folic Acid Vitamin B12

Each ingredient & the kinds of drugs it affects

For each ingredient in Apple Cider Vinegar Gummies with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Apple Cider Vinegar4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B
Apple Cider Vinegar full monograph & interactions

Folic Acid7 drug types · 40 drugs

5-Fluorouracil

Theoretically, high doses of folic acid might increase the toxicity of 5-fluorouracil.
Increases in gastrointestinal side effects of 5-fluorouracil, such as stomatitis and diarrhea, have been described in two clinical studies when leucovorin, a form of folic acid, was administered with 5-fluorouracil.

Likelihood Possible Evidence D
Capecitabine (Xeloda)

Use of high-dose folic acid might contribute to capecitabine toxicity.
Clinical research suggests that higher serum folate levels are associated with an increased risk for moderate or severe toxicity during capecitabine-based treatment for colorectal cancer. Additionally, in one case report, taking folic acid 15 mg daily might have contributed to increased toxicity, including severe diarrhea, vomiting, edema, hand-foot syndrome, and eventually death, in a patient prescribed capecitabine.

Likelihood Possible Evidence D
Methotrexate (Trexall, Others)

Folic acid might reduce the efficacy of methotrexate as a cancer treatment when given concurrently.
Methotrexate exerts its cytotoxic effects by preventing conversion of folic acid to the active form needed by cells. There is some evidence that folic acid supplements reduce the efficacy of methotrexate in the treatment of acute lymphoblastic leukemia, and theoretically they could reduce its efficacy in the treatment of other cancers. Advise cancer patients to consult their oncologist before using folic acid supplements. In patients treated with long-term, low-dose methotrexate for rheumatoid arthritis (RA) or psoriasis, folic acid supplements can reduce the incidence of side effects, without reducing efficacy.

Likelihood Probable Evidence B
Phenobarbital (Luminal)

Folic acid might have antagonistic effects on phenobarbital and increase the risk for seizures.
Folic acid can have direct convulsant activity in some people, reversing the effects of phenobarbital and worsening seizure control. Monitor closely for increased seizure activity.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Folic acid might reduce serum levels of phenytoin in some patients.
Folic acid may be a cofactor in phenytoin metabolism. Folic acid, in doses of 1 mg daily or more, can reduce serum levels of phenytoin in some patients. Increases in seizure frequency have been reported. If folic acid supplements are added to established phenytoin therapy, monitor serum phenytoin levels closely. If phenytoin and folic acid are started at the same time and continued together, adverse changes in phenytoin pharmacokinetics are avoided. Note that phenytoin also reduces serum folate levels.

Likelihood Probable Evidence B
Primidone (Mysoline)

Folic acid might have antagonistic effects on primidone and increase the risk for seizures.
Folic acid can have direct convulsant activity in some people, reversing the effects of primidone and worsening seizure control. Monitor closely for increased seizure activity. Note that primidone also reduces serum folate levels.

Likelihood Probable Evidence B
Pyrimethamine (Daraprim)

Folic acid might antagonize the effects of pyrimethamine.
Folic acid can antagonize the antiparasitic effects of pyrimethamine against toxoplasmosis and Pneumocystis carinii pneumonia. Folic acid doesn't antagonize the effects of pyrimethamine in the treatment of malaria, because malarial parasites cannot use exogenous folic acid. Use folinic acid as an alternative to folic acid when indicated.

Likelihood Probable Evidence D
Folic Acid full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Apple Cider Vinegar Gummies, from the product label.

Goli Nutrition

See all Goli Nutrition products
Name
Goli Nutrition Inc.
City
West Hollywood
State
CA
ZipCode
90069
Phone Number
1-888-345-1452
Web Address
www.goli.com/ashwa
Pharmacist Counseling Corner

Apple Cider Vinegar Gummies by Goli Nutrition: Common Questions

Does Apple Cider Vinegar Gummies by Goli Nutrition interact with any medications?
Yes. Based on its ingredients, Apple Cider Vinegar Gummies has a known interaction with 339 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Apple Cider Vinegar Gummies contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take these gummies if I'm pregnant or breastfeeding?
Folic acid and vitamin B12 are both considered safe during pregnancy and breastfeeding at recommended amounts—in fact, folic acid is recommended during pregnancy to help prevent birth defects. However, folic acid use late in pregnancy has been linked in population studies to increased childhood asthma and respiratory infections, while early pregnancy use has not. Talk with your obstetrician or midwife about whether this product is right for you, since it also contains sodium and apple cider vinegar for which pregnancy/breastfeeding data is limited or flagged as possibly unsafe.
What dose of folic acid is in each gummy, and is it safe?
The product facts don't specify the per-gummy dose of folic acid. Folic acid is generally well tolerated at recommended doses, but doses of 5 mg daily or higher can cause abdominal cramps, diarrhea, and rash, and 15 mg daily can cause confusion, sleep problems, and hyperactivity. Check the label for the exact amount per serving, and talk with your pharmacist if you're taking other sources of folic acid or if you have concerns about dosage.
Will these gummies help my blood sugar if I have diabetes?
Apple cider vinegar might reduce blood sugar levels, so theoretically it could have additive effects if you take diabetes medication—but the evidence isn't conclusive, and we don't have clear data on how much vinegar is needed or how strong the effect is. If you use insulin or diabetes drugs, check with your pharmacist first, since there's a documented Minor interaction risk with antidiabetes medications.
Are there any side effects from taking these gummies?
At normal doses, the ingredients are generally well tolerated. Folic acid can cause abdominal cramps, diarrhea, and rash at higher doses (5 mg daily and above). Apple cider vinegar in food amounts is safe, but large or long-term medicinal doses may cause low potassium, which can affect your heart and bones. Vitamin B12 is very safe and well tolerated, with only rare allergic reactions reported.
Can I take these if I have high blood pressure?
These gummies contain sodium, which can increase blood pressure, and theoretically high sodium intake might reduce how well your blood pressure medications work. If you have high blood pressure or take blood pressure medications, check with your pharmacist before starting these gummies to make sure they won't interfere with your treatment.
What is the apple cider vinegar in these for?
Apple cider vinegar is a fermented apple juice that's marketed for various health claims—acne, cognitive function, dental plaque, and others. However, we don't have reliable evidence that it works for any of these yet. It's been used in food for a long time and is well tolerated in food amounts, but large doses over time can cause low potassium and bone loss.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Apple Cider Vinegar Gummies label
Go deeper

The Full Monographs Behind Apple Cider Vinegar Gummies’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Folic Acid

Interacts with 40 drugs

Folic acid is the man-made form of vitamin B9 and is one of the most well-studied supplements, especially for preventing serious birth defects when taken before and during early pregnancy. I...

Read the full Folic Acid monograph → Herb & supplement monograph

Apple Cider Vinegar

Interacts with 162 drugs

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...

Read the full Apple Cider Vinegar monograph →
Sources

Sources & How We Checked

Apple Cider Vinegar Gummies's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 135 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Folic Acid 56 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Duhra P. Treatment of gastrointestinal symptoms associated with methotrexate therapy for psoriasis. J Am Acad Dermatol 1993;28:466-9. PubMed
  3. Morgan SL, Baggott JE, Vaughn WH, et al. Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial. Ann Intern Med 1994;121:833-41. PubMed
  4. Froscher W, Maier V, Laage M, et al. Folate deficiency, anticonvulsant drugs, and psychiatric morbidity. Clin Neuropharmacol 1995;18:165-82. PubMed
  5. Lewis DP, Van Dyke DC, Willhite LA, et al. Phenytoin-folic acid interaction. Ann Pharmacother 1995;29:726-35. PubMed
  6. Berg MJ, Stumbo PJ, Chenard CA, et al. Folic acid improves phenytoin pharmacokinetics. J Am Diet Assoc 1995;95:352-6. PubMed
  7. Berg MJ, Fincham RW, Ebert BE, et al. Phenytoin pharmacokinetics: Before and after folic acid administration. Epilepsia 1992;33:712-20. PubMed
  8. Shafer RB, Nuttall FQ. Calcium and folic acid absorption in patients taking anticonvulsant drugs. J Clin Endocrinol Metab 1975;41:1125-9. PubMed
  9. Leeb BF, Witzmann G, Ogris E, et al. Folic acid and cyanocobalamin levels in serum and erythrocytes during low-dose methotrexate therapy of rheumatoid arthritis and psoriatic arthritis patients. Clin Exp Rheumatol 1995;13:459-63.
  10. Morgan SL, Baggott JE, Lee JY, Alarcón GS. Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during longterm, low dose methotrexate therapy for rheumatoid arthritis: implications for cardiovascular disease preventi
  11. Dijkmans BA. Folate supplementation and methotrexate. Br J Rheumatol 1995;34:1172-4. PubMed
  12. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  13. Lambie DG, Johnson RH. Drugs and folate metabolism. Drugs 1985;30:145-55. PubMed
  14. Amer College of Rheumatology ad hoc committee on clinical guidelines. Guidelines for monitoring drug therapy in rheumatoid arthritis. Arthritis Rheum 1996;39:723-31. DOI
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Sodium 38 references
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Vitamin B12 30 references
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  20. Kartel O, Gulec M, Demirel F, et al. Vitamin B12 allergy and successful desensitization with cyanocobalamin: A case report. Allergol Immunopath (Madr) 2012;40(5):324-5.
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Apple Cider Vinegar 11 references
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  6. Bunick CG, Lott JP, Warren CB, et al. Chemical burn from topical apple cider vinegar. J Am Acad Dermatol 2012;67(4):e143-4. PubMed
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