Major interaction on record — check this product against your medications before combining. Based on 3 of 7 ingredients. Check your meds →
Dietary supplement

Baby Probiotic Powder with Colostrum Unflavored Ingredients & Drug Interactions

by GNC Milestones

Powder Category: Non-nutrient/non-botanical
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Baby Probiotic Powder with Colostrum Unflavored is a dietary supplement by GNC Milestones with 7 active ingredients. Its ingredients are commonly taken for digestive health and regularity, constipation relief, immune support.Based on those ingredients, 318 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Bifidobacterium animalis subsp. lactis (CUL 34 ), Bifidobacterium bifidum (CUL 20), Saccharomyces cerevisiae subsp. boulardii (CNCM-I-1079). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Baby Probiotic Powder with Colostrum Unflavored by GNC Milestones

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 6 active ingredients.
  • “LAB4B Probiotics” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This powder contains 6 active ingredients: two Bifidobacterium strains (animalis subsp. lactis and bifidum), two Lactobacillus strains (salivarius and paracasei), brewer's yeast (Saccharomyces cerevisiae subsp. boulardii), and colostrum. The first five are live probiotics—beneficial bacteria and yeast intended to support digestive and immune health.

Colostrum is the early milk produced after birth, rich in antibodies and nutrients. The product also contains inactive ingredients (potato maltodextrin and rice hull concentrate) as carriers and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Digestive health and immune support for infants.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Diarrhea, Irritable bowel syndrome (IBS), Malnourishment-related diarrhea — and 4 related terms.
  • The strongest evidence on file: Brewer's Yeast is rated "Possibly Effective" for Irritable bowel syndrome (IBS) (Natural Medicines).
  • Also on file: Bifidobacterium Animalis Subsp. Lactis is rated "Possibly Effective" for Constipation, Irritable bowel syndrome (IBS), Colic.
  • Also on file: Bifidobacterium Bifidum is rated "Possibly Effective" for Irritable bowel syndrome (IBS).

The probiotics in this product show some evidence for digestive and respiratory support. Both Bifidobacterium strains are rated Possibly Effective for irritable bowel syndrome (IBS) and respiratory tract infections, while B. lactis is also Possibly Effective for constipation.

Brewer's yeast is Possibly Effective for IBS as well. For other conditions listed—hay fever, Alzheimer disease, anxiety, C. difficile infection, influenza, and high cholesterol—the evidence we hold is insufficient to rate effectiveness.

Colostrum's effectiveness for any condition is not established in the data we have.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both Bifidobacterium strains and brewer's yeast are generally well tolerated by healthy people when taken as directed. The most common side effect reported with B. lactis is diarrhea; B. bifidum and brewer's yeast can cause bloating, flatulence, and abdominal discomfort.

Rare serious concerns include possible infection risk with probiotics in people with weakened immune systems, and rare cases of anaphylaxis or severe reaction with brewer's yeast in sensitive individuals. For pregnancy and lactation, B. bifidum is rated Possibly Safe during pregnancy, but data for the other ingredients is either limited or not on file—talk with your pediatrician before giving this to your baby.

Safety data for colostrum during infancy is not on file in our data.

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Brewer's Yeast, Bifidobacterium Animalis Subsp. Lactis, Bifidobacterium Bifidum.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 318 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before giving this to your baby, check whether they take MAOIs (a Major interaction with brewer's yeast), antibiotics or antifungals (Moderate to Minor interactions with the probiotic strains), antidiabetes drugs (Moderate with brewer's yeast), or lithium (Moderate with brewer's yeast). If your baby is on any prescription, ask your pediatrician or pharmacist to verify these against the product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This probiotic powder may help support infant digestive and respiratory health, but it's designed for babies and should only be given under pediatric guidance. If your baby takes any antibiotics, MAOIs (rare in infants, but important to know), antifungals, or antidiabetes medications, check with your pediatrician first.

Run your baby's full medication list through the tool below before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Baby Probiotic Powder with Colostrum Unflavored, straight from the product label.

Brand GNC Milestones
Barcode (UPC) 048107179359
Net contents 0.07 oz.; 2 Gram(s)
Market status On market
Date entered into DSLD Aug 23, 2019
DSLD ID 206322
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Children (All), Infants/Baby (0 - 1 Year)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Baby Probiotic Powder with Colostrum Unflavored by GNC Milestones, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Packet(s)
Maximum serving Sizes:
1 Packet(s)
UPC/BARCODE
048107179359
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates1 Gram(s)--
Saturated Fat1 Gram(s)5%
Total Fat1 Gram(s)1%
Protein1 Gram(s)--
Total Sugars0.5 Gram(s)--
LAB4B Probiotics0 NP--
Bifidobacterium animalis subsp. lactis (CUL 34 )0 NP--
Bifidobacterium bifidum (CUL 20)0 NP--
Lactobacillus salivarius (CUL 61)0 NP--
Lactobacillus paracasei (CUL 08)0 NP--
Saccharomyces cerevisiae subsp. boulardii (CNCM-I-1079)0 NP--
Colostrum1500 mg--

Other ingredients: Potato Maltodextrin, Rice hull concentrate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of reach of children.

Contains: Milk.

Storage

Store in a cool, dry place. No refrigeration required.

FDA Statement of Identity

Dietary Supplement

General Statements

Made in the UK

Formula

Contains: Milk.

See for yourself

Baby Probiotic Powder with Colostrum Unflavored by GNC Milestones label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Baby Probiotic Powder with Colostrum Unflavored by GNC Milestones

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Packet(s) Dosage formPowder Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

1 Gram(s) per serving

LAB4B Probiotics

0 NP per serving
0 NP per serving

Brewer's yeast is a nutrient-rich fungus that provides B vitamins, protein, and minerals, and a related yeast product (S. boulardii) is used for some...

Saccharomyces cerevisiae subsp. boulardii (CNCM-I-1079) monograph & interactions

Colostrum

1500 mg per serving Form: Immunoglobulin G1 + G2

Other (inactive) ingredients: Potato Maltodextrin, Rice hull concentrate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Baby Probiotic Powder with Colostrum Unflavored by GNC Milestones Drug Interactions

Want to check YOUR meds against Baby Probiotic Powder with Colostrum Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
318Drugs
9 Major 269 Moderate 40 Minor

Each ingredient & the kinds of drugs it affects

For each ingredient in Baby Probiotic Powder with Colostrum Unflavored with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium animalis subsp. lactis (CUL 34 )1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium lactis with antibiotic drugs might decrease the effectiveness of B. lactis.
Since B. lactis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. lactis preparations by at least 2 hours.

Likelihood Probable Evidence D

Bifidobacterium bifidum (CUL 20)1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.

Likelihood Probable Evidence D

Saccharomyces cerevisiae subsp. boulardii (CNCM-I-1079)4 drug types · 136 drugs

Monoamine Oxidase Inhibitors (Maois)

Theoretically, taking brewer's yeast with MAOIs might increase the risk of hypertension.
Brewer's yeast contains tyramine. Taking brewer's yeast with MAOIs might increase the risk for hypertensive crisis.

Likelihood Likely Evidence D
Antidiabetes Drugs

Taking brewer's yeast with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking chromium-containing brewer's yeast can decrease levels of blood glucose in diabetic patients being treated with antidiabetes drugs.

Likelihood Possible Evidence B
Lithium

Theoretically, taking brewer's yeast with lithium might cause additive effects and side effects.
Some brewer's yeast products contains lithium.

Likelihood Possible Evidence D
Antifungals

Theoretically, taking antifungals with some brewer's yeast products might decrease the effectiveness of brewer's yeast.
Some brewer's yeast products contain live yeast. Therefore, simultaneously taking antifungals might kill a significant number of the organisms.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Baby Probiotic Powder with Colostrum Unflavored, from the product label.

GNC Milestones

See all GNC Milestones products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Baby Probiotic Powder with Colostrum Unflavored by GNC Milestones: Common Questions

Does Baby Probiotic Powder with Colostrum Unflavored by GNC Milestones interact with any medications?
Yes. Based on its ingredients, Baby Probiotic Powder with Colostrum Unflavored has a known interaction with 318 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Baby Probiotic Powder with Colostrum Unflavored contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I give this to my baby if they're on antibiotics?
The Bifidobacterium strains in this powder may be less effective if taken at the same time as antibiotics, because the antibiotic can kill the live bacteria. Ask your pediatrician or pharmacist to space them several hours apart so the probiotic can work better.
What are the most common side effects I should watch for?
Diarrhea, bloating, and flatulence are the most common. These are usually mild and temporary. Rarely, some babies have reported abdominal discomfort. If side effects are severe or persistent, stop and call your pediatrician.
Is this safe during pregnancy and breastfeeding?
Bifidobacterium bifidum is rated Possibly Safe during pregnancy. We don't have enough safety data on file for the other ingredients during pregnancy or lactation, so talk with your OB or midwife before taking it yourself or giving it to your nursing infant.
Does this powder contain any fillers or additives?
Yes, it contains potato maltodextrin and rice hull concentrate as inactive ingredients—these are carriers and binders to hold the powder together. There are no other ingredients listed.
What is colostrum, and why is it in a baby formula?
Colostrum is the nutrient-rich milk produced right after birth, naturally high in antibodies and immune factors. It's included in this product to support infant immune and digestive health, though we don't have effectiveness evidence on file for it.
Is this the same as the probiotics given to premature babies in the hospital?
This product contains similar probiotic strains used in some clinical settings, but it's a dietary supplement, not a medical treatment. Only give it to your baby under your pediatrician's recommendation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Baby Probiotic Powder with Colostrum Unflavored is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Baby Probiotic Powder with Colostrum Unflavored label
Sources

Sources & How We Checked

Baby Probiotic Powder with Colostrum Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Animalis Subsp. Lactis 8 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Phuapradit P, Varavithya W, Vathanophas K, et al. Reduction of rotavirus infection in children receiving bifidobacteria-supplemented formula. J Med Assoc Thai 1999;82:S43-8.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  5. Taipale TJ, Pienihäkkinen K, Isolauri E, Jokela JT, Söderling EM. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in early childhood. Pediatr Res. 2016;79(1-1):65-9. PubMed
  6. Amat-Bou M, Garcia-Ribera S, Climent E, et al. Effects of Bifidobacterium animalis Subsp. lactis (BPL1) supplementation in children and adolescents with prader-willi syndrome: A randomized crossover trial. Nutrients. 2020;12(10):3123. PubMed
  7. Mäkelä SM, Forssten SD, Kailajärvi M, et al. Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti-inflammatory drug: A randomized, placebo-controlled, double-blind clinical trial. Br J Clin Ph
  8. Wildt S, Munck LK, Vinter-Jensen L, et al. Probiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis. Inflamm Bowel Dis 2006;12(5):395-401. PubMed

See these in context on the Bifidobacterium Animalis Subsp. Lactis monograph →

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Brewer's Yeast 6 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Lewis SJ, Freedman AR. Review article: the use of biotherapeutic agents in the prevention and treatment of gastrointestinal disease. Aliment Pharmacol Ther 1998;12:807-22. PubMed
  3. Bahijiri, S. M., Mira, S. A., Mufti, A. M., and Ajabnoor, M. A. The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes. Saudi.Med.J. 2000;21(9):831-837. DOI
  4. Schrauzer, G. N. and de, Vroey E. Effects of nutritional lithium supplementation on mood. A placebo-controlled study with former drug users. Biol.Trace Elem.Res. 1994;40(1):89-101. PubMed
  5. Gayathri R, Aruna T, Malar S, Shilpa B, Dhanasekar KR. Efficacy of Saccharomyces cerevisiae CNCM I-3856 as an add-on therapy for irritable bowel syndrome. Int J Colorectal Dis. 2020;35(1):139-145. PubMed
  6. Mourey F, Decherf A, Jeanne JF, et al. Saccharomyces cerevisiae I-3856 in irritable bowel syndrome with predominant constipation. World J Gastroenterol 2022;28(22):2509-2522.

See these in context on the Brewer's Yeast monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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