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Dietary supplement

Berry Well Ingredients & Drug Interactions

by Vital Kids

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Berry Well is a dietary supplement by Vital Kids with 4 active ingredients. Its ingredients are commonly taken for immune support, cold and flu prevention, digestive and gut health.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astragalus root extract, Arabinogalactan powder, Elderberry fruit extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Berry Well by Vital Kids

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Berry Well contains four active ingredients: arabinogalactan powder (from larch), astragalus root extract, isatis tinctoria root extract, and elderberry fruit extract. These are combined with inactive ingredients including glutamine, freeze-dried pineapple powder, xylitol, and silica to make up the powder formula.

The product is designed as a children's supplement blend, though the product facts don't specify the age range or intended daily dose.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Immune support for children.
  • We looked for evidence on: Common cold, Lower respiratory tract infections, Upper respiratory tract infection (URTI), Respiratory tract infections, Flu prevention, Cold prevention — and 1 related terms.
  • The closest evidence on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Lower respiratory tract infections.
  • Also on file: Isatis is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections.

The evidence supporting these ingredients is limited. Arabinogalactan has insufficient reliable evidence for common cold or cholesterol (hyperlipidemia).

Astragalus likewise shows insufficient evidence for hay fever, amenorrhea, anemia, angina, asthma, and beta-thalassemia. Isatis tinctoria is rated possibly effective for psoriasis, but insufficient evidence for respiratory infections, prostate cancer, ulcerative colitis, hepatitis, and aging skin.

Elderberry is rated insufficient for hay fever, heart disease, chronic fatigue, COPD, cognitive function, and respiratory infections. In short, none of these ingredients have established effectiveness for the conditions they're commonly used for.

The evidence, ingredient by ingredient Larch Arabinogalactan Astragalus Isatis Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Arabinogalactan is generally well tolerated as a fiber, though some people experience bloating and flatulence; long-term safety data are limited. Astragalus is generally well tolerated short-term in healthy adults, but adverse effects in trials have included dizziness and—in one case—a type of chest pain called lacunar angina (though it's unclear whether astragalus caused it).

Isatis tinctoria has limited human safety data. Elderberry from ripe, cooked fruit is generally well tolerated, but raw or unripe berries, seeds, leaves, and bark contain toxins that can cause nausea, vomiting, severe diarrhea, weakness, dizziness, numbness, and in rare cases, autoimmune hepatitis (liver inflammation).

This product is made from an extract, so it should be prepared safely, but always check the label to confirm. During pregnancy, astragalus, isatis tinctoria, and elderberry are advised against due to insufficient safety data.

Astragalus and isatis tinctoria are also not recommended while breastfeeding. Elderberry is rated likely safe in pregnancy and lactation, though safety information is still limited.

Side effects, ingredient by ingredient Larch Arabinogalactan Astragalus Isatis Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Elderberry, Astragalus, Larch Arabinogalactan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before giving Berry Well to your child, check with your pharmacist or doctor if they take immunosuppressants (like cyclosporine or tacrolimus after a transplant), lithium for mood disorders, cyclophosphamide or pazopanib for cancer, or any diabetes medication. All of these carry Moderate interactions with ingredients in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Berry Well is marketed to children, but the active ingredients lack strong evidence for their claimed uses and carry Moderate interactions with immunosuppressants, lithium, some cancer drugs, and diabetes medications. If your child takes any prescription medication—especially anything that affects the immune system, heart, cancer treatment, or blood sugar—talk with your child's doctor or pharmacist before adding this product.

Even without medications, the limited safety data and lack of proven benefit mean it's worth discussing with a healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Berry Well, straight from the product label.

Brand Vital Kids
Barcode (UPC) 693465264119
Net contents 90 Gram(s); 3.17 Ounce(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 223035
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children (All), Infants/Baby (0 - 1 Year), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Berry Well by Vital Kids, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 tsp
Maximum serving Sizes:
1 tsp
Servings per container
30
UPC/BARCODE
693465264119
IngredientAmount% DV
Arabinogalactan powder1200 mg--
Astragalus root extract240 mg--
Isatis tinctoria root extract240 mg--
Elderberry fruit extract120 mg--

Other ingredients: Glutamine, freeze dried Pineapple powder, Xylitol, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store sealed in a cool dry place

Precautions

Keep out of reach of children

Use only if safety seal is intact

Warning If pregnant, consult your physician before taking.

Inner seal may lift off when cap is removed. Seal integrity is maintained until cap is removed.

Suggested/Recommended/Usage/Directions

Recommendations 6 mos. to 3 yr. - 1/4 to 1/2 teaspoon 1 to 3 times a day; over 3 yrs. - 1/2 to 1 teaspoon 1 to 3 times a day in juice, water, soft food, or as directed by your healthcare professional.

Formulation

This product may naturally clump.

Excludes coatings, binders, gluten (wheat, rye, barley), milk/dairy (casein, whey), soy protein, egg protein, sugar. Verified by independent testing

Immune support

Raw materials and finished products are independently tested by U.S. labs. Learn more at vitalnutrients.net

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This is a statement of nutritional support. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Formulated by Josh Berry N.D.

See for yourself

Berry Well by Vital Kids label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Berry Well by Vital Kids

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.25 tsp Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Arabinogalactan powder

Interacts with
121 drugs
1200 mg per serving Form: Eastern Larch

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...

Arabinogalactan powder monograph & interactions

Astragalus root extract

Interacts with
208 drugs
240 mg per serving

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...

Astragalus root extract monograph & interactions

Isatis tinctoria root extract

No known
interactions
240 mg per serving

Isatis is a plant long used in traditional Chinese medicine, mainly for sore throats, fevers, and colds. Modern evidence in people is very limited, so...

Isatis tinctoria root extract monograph & interactions

Elderberry fruit extract

Interacts with
121 drugs
120 mg per serving

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Elderberry fruit extract monograph & interactions

Other (inactive) ingredients: Glutamine, Freeze dried Pineapple powder, Xylitol, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Berry Well by Vital Kids Drug Interactions

Want to check YOUR meds against Berry Well?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Berry Well with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Astragalus root extract4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D

Arabinogalactan powder1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D

Elderberry fruit extract2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Berry Well, from the product label.

Vital Kids

See all Vital Kids products
Name
Vital Nutrients
Street Address
45 Kenneth Dooley Dr
City
Middletown
State
CT
ZipCode
06457
Web Address
vitalnutrients.net
Pharmacist Counseling Corner

Berry Well by Vital Kids: Common Questions

Does Berry Well by Vital Kids interact with any medications?
Yes. Based on its ingredients, Berry Well has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Berry Well contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy or while breastfeeding?
The product contains astragalus and isatis tinctoria, which the safety data advises against in pregnancy and lactation due to limited information. Elderberry in this product is rated likely safe, but overall there isn't enough data to know for sure. Talk with your doctor or pharmacist for personalized guidance.
Can this cause side effects?
Arabinogalactan and astragalus may cause bloating and flatulence in some people. Astragalus has also been associated with dizziness in clinical studies. Elderberry from properly prepared ripe fruit is generally well tolerated, but raw or unripe berries can cause nausea, vomiting, severe diarrhea, and dizziness due to natural toxins. This product should be made safely, but always check the label.
Does elderberry really prevent colds?
No—elderberry is rated as having insufficient reliable evidence for respiratory infections. The same goes for the other ingredients in this blend; none have established effectiveness for the conditions they're often used for.
What is arabinogalactan and why is it in here?
Arabinogalactan is a soluble fiber extracted from larch wood. It's included because some people believe it supports immune function, though the evidence for common cold or cholesterol is insufficient. It's generally well tolerated but may cause bloating.
What about the inactive ingredients—are there fillers?
Yes, the product contains inactive ingredients including glutamine, freeze-dried pineapple powder, xylitol, and silica. These are added for texture, sweetness, or to hold the powder together. None of these are considered harmful, but if your child has allergies or sensitivities, check the full label.
Is this safe for a child with an autoimmune condition?
Because three of the four active ingredients may stimulate the immune system and could theoretically interfere with autoimmune treatments or immunosuppressants, it's important to check with your child's doctor before using this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Berry Well is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Berry Well label
Sources

Sources & How We Checked

Berry Well's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Larch Arabinogalactan 8 references
  1. D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
  2. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
  3. Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
  4. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
  5. Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
  6. Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
  7. Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
  8. Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.

See these in context on the Larch Arabinogalactan monograph →

Astragalus 13 references
  1. Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
  2. Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
  3. Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
  4. Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
  5. Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
  6. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
  7. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
  8. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
  9. Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
  10. Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
  11. Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
  12. Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
  13. Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):

See these in context on the Astragalus monograph →

Isatis 3 references
  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source
  3. About Herbs, Botanicals & Other Products — Memorial Sloan Kettering Cancer Center Source

See these in context on the Isatis monograph →

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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