No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Beta Alanine Extreme Ingredients & Drug Interactions

by Prolab

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

Beta Alanine Extreme is a dietary supplement by Prolab with 2 active ingredients. Its ingredients are commonly taken for skin conditions like eczema, anemia related to kidney disease, allergy and inflammation support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Beta Alanine Extreme by Prolab

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 2 active ingredients. L-Histidine is an amino acid with limited evidence for a few conditions; the main focus here is likely beta-alanine (CarnoSyn), which is added to support athletic and physical performance.

The capsule also contains inactive ingredients: rice flour, microcrystalline cellulose, magnesium stearate, and gelatin.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: delay muscle fatigue during exercise.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle breakdown, Physical performance, muscle endurance, high-intensity exercise capacity, carnosine buffering — and 1 related terms.
  • The strongest evidence on file: Beta-alanine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beta-alanine is rated "Possibly Effective" for Physical performance.
  • Also on file: Beta-alanine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle breakdown.

Beta-alanine is rated possibly effective for athletic performance and physical performance — meaning there's some evidence it may help, but it's not definitive. L-Histidine shows possibly effective evidence only for cholera; for eczema, rheumatoid arthritis, and kidney failure, the evidence is too weak or absent to rate it reliably.

The other claimed benefits of beta-alanine (age-related cognitive decline, COPD, cognitive function, menopausal symptoms) lack enough established evidence in the data we hold.

The evidence, ingredient by ingredient Histidine Beta-alanine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-alanine is generally well tolerated in healthy adults, but it commonly causes a harmless tingling sensation (paresthesias) and flushing, usually starting on the scalp within 20 minutes and lasting about an hour. The intensity depends on dose — it's very mild at lower amounts and more noticeable at higher ones.

The product has not been studied for long-term high-dose use. L-Histidine at dietary amounts is likely safe, but safety data on supplement doses is not well established, so caution is advised.

Beta-alanine is not recommended during pregnancy or breastfeeding due to insufficient safety information.

Side effects, ingredient by ingredient Histidine Beta-alanine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients in this product.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product is geared toward people looking to support athletic or physical performance with beta-alanine. If you're pregnant, breastfeeding, or have concerns about the tingling side effect, talk with your pharmacist or doctor first.

No drug interactions are documented, but it's still worth checking your exact medications before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta Alanine Extreme, straight from the product label.

Brand Prolab
Barcode (UPC) 750902102493
Net contents 56 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 321832
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta Alanine Extreme by Prolab, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
28
UPC/BARCODE
750902102493
IngredientAmount% DV
L-Histidine75 mg, 300 mg--
CarnoSyn800 mg, 3200 mg--

Other ingredients: Rice Flour, Microcrystalline Cellulose, Magnesium Stearate, Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Prolab Beta Alanine Extreme is a dynamic blend of CarnoSyn beta alanine and the amino acid L-Histidine, designed to delay muscle fatigue. Beta alanine floods the muscles with the specialized amino acid carnosine to work as a buffer against lactic acid buildup helping you to train at a higher intensity for a longer period of time before fatigue sets in. This product is to be used in conjunction with a healthy diet and exercise regimen.

CarnoSyn Carnosine Synthesizer

Brand IP Statement(s)

Prolab You do your part. We'll do ours.

Natural Alternatives International (NAI) is the owner of patents as listed on www.carnosyn.com and registered trademark CarnoSyn. Copyright 2020 Prolab Nutrition LLC

Prolab Performance Simplified

General Statements

Join the Prolab Nation: www.prolab.com

Precautions

Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant or lactating.

Keep out of reach of children.

Seals/Symbols

Prolab Quality Assurance

Formulation

Endurance recovery stamina Delays muscle fatigue with a loading dose of 6,400 mg per day for 6 days.

No: Milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, yeast, artificial colors or flavors, added sugar or preservatives.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 2 capsules, four times daily, with a meal.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Beta Alanine Extreme by Prolab label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Beta Alanine Extreme by Prolab

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container28 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Histidine

No known
interactions
75 mg per serving

Histidine is an essential amino acid your body needs to build proteins and to make compounds like histamine and carnosine. Most people get enough from...

L-Histidine monograph & interactions

CarnoSyn

No known
interactions
800 mg per serving Form: Beta-Alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

CarnoSyn monograph & interactions

Other (inactive) ingredients: Rice Flour, Microcrystalline Cellulose, Magnesium Stearate, Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta Alanine Extreme by Prolab Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Beta Alanine Extreme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Beta Alanine Extreme, from the product label.

Prolab

See all Prolab products
Name
Prolab Nutrition LLC
Street Address
PO Box 18215
City
Fairfield
State
OH
ZipCode
45018
Phone Number
1-833-776-5221
Web Address
www.prolab.com
Pharmacist Counseling Corner

Beta Alanine Extreme by Prolab: Common Questions

Does Beta Alanine Extreme by Prolab interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Beta Alanine Extreme. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Beta Alanine Extreme contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will I get that tingling feeling everyone talks about with beta-alanine?
You might. Beta-alanine commonly causes a harmless pins-and-needles sensation and skin flushing, usually starting on the scalp within 20 minutes and lasting about an hour. How intense it is depends on your dose — lower amounts cause mild or no tingling, while higher doses make it more noticeable. It's not dangerous, just uncomfortable for some people.
Is this safe to take while pregnant?
No. Beta-alanine is best avoided during pregnancy because there isn't enough safety information. L-Histidine at dietary amounts is likely safe in pregnancy, but we don't have reliable data on supplement doses of it either. Talk with your doctor or pharmacist before taking any supplement while pregnant.
Can I take this while breastfeeding?
Beta-alanine is best avoided while breastfeeding due to insufficient safety information. There's no reliable data on L-Histidine supplementation during breastfeeding either. Check with your doctor or pharmacist first.
What is L-Histidine supposed to do in this product?
L-Histidine has possibly effective evidence only for cholera. For other conditions like eczema, rheumatoid arthritis, and kidney failure, the evidence is too weak to rate it reliably. The main active ingredient driving the product's claims is beta-alanine, not L-Histidine.
Does this actually improve athletic performance?
Beta-alanine is rated possibly effective for athletic and physical performance, meaning there's some evidence it may help — but the evidence isn't conclusive. Results vary from person to person, and the effect is modest.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beta Alanine Extreme is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta Alanine Extreme label
Sources

Sources & How We Checked

Beta Alanine Extreme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Histidine 3 references
  1. Histidine — MedlinePlus (U.S. National Library of Medicine) Source
  2. Amino Acids — MedlinePlus (U.S. National Library of Medicine) Source
  3. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

See these in context on the Histidine monograph →

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
  4. Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
  5. Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
  6. Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
  7. Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
  8. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
  9. Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
  10. Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
  11. da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
  12. Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
  13. Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed

See these in context on the Beta-alanine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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