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Dietary supplement

Blueberry Extract 250 mg Ingredients & Drug Interactions

by Indiana Botanic Gardens

Blueberry Extract 250 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Blueberry Extract 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Blueberry Extract 250 mg is a dietary supplement by Indiana Botanic Gardens with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Wild Blueberry extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Blueberry Extract 250 mg by Indiana Botanic Gardens

Ask about any prescription or over-the-counter medication and we check it for interactions with Blueberry Extract 250 mg by Indiana Botanic Gardens — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Blueberry Extract 250 mg by Indiana Botanic Gardens

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: wild blueberry extract at 250 mg per capsule. The extract comes from the fruit and is intended to deliver the plant's natural compounds in concentrated form.

The capsule itself is made from gelatin, and the formula also contains rice flour and magnesium stearate as inactive ingredients to hold everything together and fill out the capsule.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Blueberry product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Blueberry's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“Antioxidant support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence for blueberry extract is mixed and often limited. For high blood pressure (hypertension), the data suggests it is possibly ineffective — meaning current studies don't support a benefit.

For age-related cognitive decline, anxiety, athletic performance, high cholesterol (hyperlipidemia), and cardiovascular disease, there isn't enough reliable evidence yet to rate how well it works. If you're considering this supplement for one of these reasons, talk it over with your doctor or pharmacist about whether the evidence supports its use for your situation.

The evidence, ingredient by ingredient Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberries eaten as food are generally well tolerated and safe for most people. This concentrated supplement, however, has not been well studied in pregnancy or during breastfeeding, so the safety data advises caution if you're pregnant or nursing — talk with your doctor or pharmacist for personalized guidance.

The most common side effects reported with freeze-dried blueberries are constipation, diarrhea, nausea, and vomiting. In one clinical trial, about a quarter of participants taking a high daily dose stopped within the first week due to stomach upset.

Side effects, ingredient by ingredient Blueberry

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blueberry.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs, be aware that blueberry extract may lower blood glucose and raise the risk of low blood sugar — watch for shakiness, sweating, or confusion and check your numbers more often. Also double-check before taking this product if you use flurbiprofen (Ansaid) or buspirone (BuSpar), as blueberry may slow how your body clears these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Only minor medication interactions are documented, and safety information is well characterized.

Blueberry extract is generally well tolerated, but it may interact with blood sugar medications, pain relievers like flurbiprofen, and anti-anxiety drugs like buspirone. If you take any medications for diabetes, pain, or anxiety, check with your doctor or pharmacist before starting this product.

Pregnant or breastfeeding? Talk it over with your healthcare provider first, since safety data is limited in those situations.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blueberry Extract 250 mg, straight from the product label.

Brand Indiana Botanic Gardens
Barcode (UPC) 703308010732
Net contents 30 Capsule(s); 250 mg
Market status On market
Date entered into DSLD Jun 25, 2015
DSLD ID 46786
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blueberry Extract 250 mg by Indiana Botanic Gardens, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
703308010732
IngredientAmount% DV
Wild Blueberry extract250 mg--

Other ingredients: Rice Flour, Gelatin Capsule, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule daily, with a snack, as a dietary supplement, or as directed by a physician.

Precautions

Warning: If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.

For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)

KEEP OUT OF REACH OF CHILDREN

General Statements

Best if used by date on bottle.

Antioxidant Support

Storage

Store in a dry, cool place.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

THIS STATEMENT HAS NOT BEEN EVALUATED BY THE FOOD & DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

Seals/Symbols

IBG INDIANA BOTANIC GARDENS(R)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Blueberry Extract 250 mg by Indiana Botanic Gardens label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Blueberry Extract 250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Blueberry Extract 250 mg by Indiana Botanic Gardens

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Wild Blueberry extract

Interacts with
88 drugs
250 mg per serving Form: Total Anthocyanins

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...

Wild Blueberry extract monograph & interactions

Other (inactive) ingredients: Rice Flour, Gelatin Capsule, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blueberry Extract 250 mg by Indiana Botanic Gardens Drug Interactions

Want to check YOUR meds against Blueberry Extract 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
88Drugs
88 Minor

Ingredients driving the most interactions

Wild Blueberry extract 88

Individual Drug Interactions

The ingredients in Blueberry Extract 250 mg interact with 88 drugs. Click any drug to see the details.

1 of the 1 ingredient in Blueberry Extract 250 mg interact with drugs. Each result below shows which ingredient is responsible. Wild Blueberry extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Blueberry Extract 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wild Blueberry extract3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
Wild Blueberry extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Blueberry Extract 250 mg, from the product label.

Indiana Botanic Gardens

See all Indiana Botanic Gardens products
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Blueberry Extract 250 mg by Indiana Botanic Gardens: Common Questions

Does Blueberry Extract 250 mg by Indiana Botanic Gardens interact with any medications?
Yes. Based on its ingredients, Blueberry Extract 250 mg has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blueberry Extract 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises caution. Eating blueberries as food is fine during pregnancy and breastfeeding, but concentrated supplements like this haven't been well studied in those situations. Talk with your doctor or pharmacist to decide what's right for you.
What are the side effects I should watch for?
Blueberry extract is generally well tolerated, but some people report constipation, diarrhea, nausea, or vomiting — especially at higher doses. In one trial, about one in four people taking a large daily dose experienced stomach upset bad enough to quit within the first week.
Does blueberry extract really lower blood pressure?
The current evidence suggests it's possibly ineffective for high blood pressure, meaning studies haven't shown a real benefit. For the other conditions this supplement is marketed for — like heart health or brain function — we don't yet have enough reliable evidence to say whether it works.
What exactly is wild blueberry extract?
It's a concentrated form of the blueberry fruit, containing the plant's natural compounds in a single 250 mg dose. The extract is put into a gelatin capsule along with rice flour and magnesium stearate to form the tablet.
Can I take this with my diabetes medication?
Animal and lab research suggests blueberry extract may lower blood sugar levels. If you take diabetes medication, there's a theoretical risk of low blood sugar when combined. Check with your doctor or pharmacist before starting, and if you do take both, monitor your blood glucose more closely.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blueberry Extract 250 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blueberry Extract 250 mg label
Go deeper

The Full Monographs Behind Blueberry Extract 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blueberry

Interacts with 88 drugs

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...

Read the full Blueberry monograph →
Sources

Sources & How We Checked

Blueberry Extract 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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