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Dietary supplement

Blueberry Extract Ingredients & Drug Interactions

by DC

Blueberry Extract label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Blueberry Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Blueberry Extract is a dietary supplement by DC with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Blueberry 25:1 extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Blueberry Extract by DC

Ask about any prescription or over-the-counter medication and we check it for interactions with Blueberry Extract by DC — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Blueberry Extract by DC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains one active ingredient: blueberry 25:1 extract, a concentrated form of blueberry. The extract is suspended in inactive ingredients including gelatin, soybean oil, glycerin, soy lecithin, beeswax, and caramel color, which serve as the capsule and delivery system.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Blueberry product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Blueberry's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“antioxidant support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence for blueberry extract is mixed. For hypertension (high blood pressure), it's rated possibly ineffective — meaning the available data do not support its use.

For age-related cognitive decline, anxiety, athletic performance, cardiovascular disease, and high cholesterol (hyperlipidemia), the evidence is insufficient to rate it one way or the other. That means we don't have enough reliable data in our monograph to say whether it works for these purposes.

The evidence, ingredient by ingredient Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberries as whole food are safe and widely eaten. The blueberry extract itself is generally well tolerated when taken by mouth.

However, freeze-dried blueberries — which may be similar to this concentrated extract — have caused constipation, diarrhea, nausea, and vomiting in some people; in one clinical trial, about a quarter of participants taking 50 grams daily stopped due to stomach complaints in the first week. For pregnancy, the safety data advises caution: eating blueberries is fine, but concentrated supplements have not been well studied during pregnancy.

The safety of high-dose extracts while breastfeeding is also unknown. If you're pregnant or breastfeeding, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Blueberry

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blueberry.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist if you take antidiabetes drugs (insulin, metformin, sulfonylureas, and others) — blueberry extract might increase the risk of low blood sugar. Also double-check if you take flurbiprofen or buspirone, as blueberry extract may raise their blood levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Only minor medication interactions are documented, and safety information is well characterized.

Blueberry Extract by DC may appeal to people looking for cardiovascular or cognitive support, though the evidence for most of those uses is not yet established. If you take antidiabetes drugs, flurbiprofen, or buspirone, check your exact medications with your doctor or pharmacist before starting it.

Stomach upset is possible, especially at higher doses. Talk with your own healthcare provider about whether this product fits your health plan.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blueberry Extract, straight from the product label.

Brand DC
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 245302
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blueberry Extract by DC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
IngredientAmount% DV
Blueberry 25:1 extract60 mg--

Other ingredients: Gelatin, Soybean Oil, Glycerin, Soy Lecithin, yellow Beeswax, natural Caramel color

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Blueberry possesses antioxidant properties that help neutralize cell-damaging free radicals.

Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing do not take this product.

Contains soy ingredients.

Formulation

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Contains: No artificial flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no wheat, no yeast, no fish, Non-GMO.

Gluten free

Helps neutralize cell damaging free radicals

Made in USA

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Quali Pure

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 softgel daily.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Blueberry Extract by DC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Blueberry Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Blueberry Extract by DC

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Blueberry 25:1 extract

Interacts with
88 drugs
60 mg per serving

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...

Blueberry 25:1 extract monograph & interactions

Other (inactive) ingredients: Gelatin, Soybean Oil, Glycerin, Soy Lecithin, Yellow Beeswax, Natural Caramel color. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blueberry Extract by DC Drug Interactions

Want to check YOUR meds against Blueberry Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
88Drugs
88 Minor

Ingredients driving the most interactions

Blueberry 25:1 extract 88

Individual Drug Interactions

The ingredients in Blueberry Extract interact with 88 drugs. Click any drug to see the details.

1 of the 1 ingredient in Blueberry Extract interact with drugs. Each result below shows which ingredient is responsible. Blueberry 25:1 extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Blueberry Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blueberry 25:1 extract3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
Blueberry 25:1 extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Blueberry Extract, from the product label.

DC

See all DC products
Name
Dee Cee Laboratories, Inc.
Street Address
304 Dee Cee Rd.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Blueberry Extract by DC: Common Questions

Does Blueberry Extract by DC interact with any medications?
Yes. Based on its ingredients, Blueberry Extract has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blueberry Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will blueberry extract lower my blood sugar?
Animal and laboratory research suggests blueberry extract can lower blood glucose levels. That's why it theoretically could increase the risk of low blood sugar (hypoglycemia) if you're already taking an antidiabetes drug. If you have diabetes or prediabetes and take any diabetes medication, talk with your doctor or pharmacist before adding this product.
Can I take this if I'm pregnant or breastfeeding?
Eating blueberries is fine during pregnancy and breastfeeding, but concentrated supplements like this extract haven't been well studied in either. The safety data we have is not complete enough to say it's safe or unsafe. Talk with your doctor or pharmacist for personalized advice.
What side effects might I experience?
Blueberry extract is generally well tolerated. However, freeze-dried blueberries — which are similar to this extract — can cause constipation, diarrhea, nausea, and vomiting. In one trial, about a quarter of people taking 50 grams daily had stomach problems bad enough to quit in the first week.
Does blueberry extract actually help with cognitive decline or heart health?
The evidence isn't established yet in our data. For age-related cognitive decline and cardiovascular disease, we have insufficient reliable evidence to say whether it works. For high cholesterol, the evidence is also rated insufficient. For blood pressure, it's rated possibly ineffective.
What's in this capsule besides blueberry?
The inactive ingredients are gelatin, soybean oil, glycerin, soy lecithin, beeswax, and caramel color — these are the capsule and delivery system. If you're allergic to soy, note that it contains soybean oil and soy lecithin.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blueberry Extract label
Go deeper

The Full Monographs Behind Blueberry Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blueberry

Interacts with 88 drugs

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...

Read the full Blueberry monograph →
Sources

Sources & How We Checked

Blueberry Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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