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Dietary supplement

Blueberry Extract Powder 500 mg Ingredients & Drug Interactions

by BulkSupplements.com

Powder Category: Botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Blueberry Extract Powder 500 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Blueberry Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Blueberry Extract Powder 500 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: blueberry fruit extract at 500 mg per serving. The only other ingredient listed is maltodextrin, an inactive filler used to make the powder.

Blueberry extract is a concentrated form of compounds from blueberry fruit. Because it's a powder, you're getting a more potent dose than eating fresh blueberries would provide.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Blueberry product and its label doesn't state a use — see Blueberry's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for blueberry extract is mixed and mostly limited. It's rated possibly ineffective for high blood pressure.

For age-related cognitive decline, anxiety, athletic performance, high cholesterol (hyperlipidemia), and heart disease prevention, there isn't enough reliable evidence yet to know whether it works. The data we hold doesn't establish that this extract is effective for any of these uses.

The evidence, ingredient by ingredient Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberries as food are generally well tolerated and widely eaten without issue. However, concentrated supplements like this one haven't been thoroughly studied in pregnancy or while breastfeeding—the facts indicate concentrated extracts carry unknown risks in those situations, so talk with your doctor or pharmacist if you're pregnant, planning pregnancy, or nursing.

Orally, blueberry extract is generally well tolerated, though some people report constipation, diarrhea, nausea, or vomiting. Freeze-dried blueberries in particular caused gastrointestinal upset in a small number of trial participants—about a quarter of one study group dropped out in the first week due to stomach complaints.

Side effects, ingredient by ingredient Blueberry

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blueberry.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take antidiabetes drugs (risk of low blood sugar), flurbiprofen (Ansaid) or other pain relievers that work similarly, or buspirone (BuSpar). All three have Minor-severity documented interactions with blueberry extract.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Blueberry extract may appeal to you if you're interested in antioxidant support, but the evidence for specific health benefits is thin or absent. If you take diabetes medications, pain relievers like flurbiprofen, or anxiety medications like buspirone, check your exact drugs with the tool on this page first.

Pregnant or breastfeeding? Talk to your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blueberry Extract Powder 500 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X000Y1QCJ9
Net contents 100 Gram(s); 3.5 Ounce(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 330450
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blueberry Extract Powder 500 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
200
UPC/BARCODE
X000Y1QCJ9
IngredientAmount% DV
Blueberry Fruit Extract500 mg--

Other ingredients: Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Blueberry Extract Powder 500 mg per serving

Brand IP Statement(s)

BulkSupplements.com Clean & pure bulk supplements

Formulation

Free of: Added sugar, soy, dairy, yeast, gluten

Color may vary

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 500 mg (about 1/5 tsp) once or twice daily, or as directed by a physician.

General Statements

Use an accurate milligram scale.

New

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

See for yourself

Blueberry Extract Powder 500 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Blueberry Extract Powder 500 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container200 Amounts shown are per serving.

Blueberry Fruit Extract

Interacts with
88 drugs
500 mg per serving

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...

Blueberry Fruit Extract monograph & interactions

Other (inactive) ingredients: Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blueberry Extract Powder 500 mg by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Blueberry Extract Powder 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
88Drugs
88 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Blueberry Extract Powder 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blueberry Fruit Extract3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Blueberry Extract Powder 500 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Blueberry Extract Powder 500 mg by BulkSupplements.com: Common Questions

Does Blueberry Extract Powder 500 mg by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Blueberry Extract Powder 500 mg has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blueberry Extract Powder 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is blueberry extract safe to take while I'm pregnant?
The facts show concentrated blueberry extracts haven't been well studied in pregnancy. Eating blueberries as food is fine, but a high-dose supplement like this one carries unknown risks. Talk with your doctor or pharmacist for personalized advice based on your situation.
What's the difference between this powder and eating fresh blueberries?
This is a concentrated extract—you're getting a much higher dose of blueberry compounds in a small amount of powder than you'd get from eating fresh fruit. That concentration is why the safety profile for supplements hasn't been as well studied as for whole blueberries as food.
Can blueberry extract help with my blood sugar?
Animal and lab research suggests blueberry extract might lower blood glucose levels, which is why it could theoretically increase low blood sugar risk if you take diabetes medications. But we don't have solid human evidence that it actually works for blood sugar control on its own.
What side effects might I experience?
Most people tolerate it well, but some experience constipation, diarrhea, nausea, or vomiting—especially with freeze-dried forms. In one study, about a quarter of participants taking a higher dose stopped within the first week due to stomach upset.
Does this powder have any fillers?
Yes—maltodextrin is listed as an inactive ingredient. It's a common filler used to make powders easier to mix and measure.
Does blueberry extract actually work for memory or thinking problems?
The evidence isn't established in the data we hold. Age-related cognitive decline is rated as having insufficient reliable evidence, so we can't say whether this extract helps with memory or mental clarity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blueberry Extract Powder 500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blueberry Extract Powder 500 mg label
Go deeper

The Full Monographs Behind Blueberry Extract Powder 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Blueberry Extract Powder 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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