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Dietary supplement

Blueberry Leaf Extract 60 mg Ingredients & Drug Interactions

by Botanic Choice

Blueberry Leaf Extract 60 mg label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Blueberry Leaf Extract 60 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Blueberry Leaf Extract 60 mg is a dietary supplement by Botanic Choice with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Blueberry extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Blueberry Leaf Extract 60 mg by Botanic Choice

Ask about any prescription or over-the-counter medication and we check it for interactions with Blueberry Leaf Extract 60 mg by Botanic Choice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Blueberry Leaf Extract 60 mg by Botanic Choice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Blueberry Leaf Extract contains one active ingredient: blueberry extract at 60 mg per softgel capsule. The extract is delivered in a softgel capsule made with gelatin, soybean oil, vegetable glycerin, soy lecithin, beeswax, caramel, and purified water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: natural antioxidant protection.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for blueberry extract's effectiveness is mixed. For hypertension (high blood pressure), it's rated possibly ineffective.

For age-related cognitive decline, anxiety, athletic performance, high cholesterol (hyperlipidemia), and cardiovascular disease, the evidence is insufficient to rate — meaning we don't yet have reliable data either way on how well it works for those purposes.

The evidence, ingredient by ingredient Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberries as food are generally well tolerated and widely eaten. When taken as an oral supplement, blueberry is also generally well tolerated, though freeze-dried blueberries in particular have been linked to constipation, diarrhea, nausea, and vomiting; in one trial, a quarter of participants taking a high dose stopped within the first week due to stomach complaints.

For pregnancy, the product facts rate blueberry extract as likely safe, though concentrated supplements have not been well studied in pregnancy — so if you're pregnant, talk it over with your doctor or pharmacist. For breastfeeding, the safety of high-dose extracts is unknown; eating blueberries as food is fine, but concentrated supplements warrant a conversation with your healthcare provider.

Side effects, ingredient by ingredient Blueberry

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blueberry.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you're on antidiabetes drugs (minor interaction risk of low blood sugar), buspiron or other anti-anxiety medications (minor risk of increased blood levels), or flurbiprofen or related nonsteroidal anti-inflammatories (minor risk of increased levels). Use the medication checker on this page to search your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Blueberry Leaf Extract may be worth considering if you're interested in general antioxidant support, though evidence for specific health claims is limited or lacking. If you take blood sugar medications or anti-anxiety drugs like buspiron, or take flurbiprofen for pain, you'll want to check with your doctor or pharmacist before starting this, since the extract could theoretically raise levels of those medications in your blood.

Pregnant or breastfeeding women should confirm with their doctor or pharmacist whether this extract is right for them.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blueberry Leaf Extract 60 mg, straight from the product label.

Brand Botanic Choice
Barcode (UPC) 703308830590
Net contents 90 Softgel(s)
Market status On market
Date entered into DSLD Sep 21, 2017
DSLD ID 78374
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blueberry Leaf Extract 60 mg by Botanic Choice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Softgel(s)
Maximum serving Sizes:
3 Softgel(s)
UPC/BARCODE
703308830590
IngredientAmount% DV
Total Fat3 Gram(s)5%
Blueberry extract180 mg--

Other ingredients: Gelatin, Soybean Oil, Vegetable Glycerin, Soy Lecithin, yellow Beeswax, Caramel, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

General Statements

Trusted since 1910 Essentials

Natural antioxidant protection

Actual pill size

Formulation

Gluten free Non GMO

Seals/Symbols

Non GMO

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 to 3 softgels daily, with a meal, as a dietary supplement, or as directed by a physician.

Precautions

Warning: If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.

For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)

Keep out of reach of children

FDA Disclaimer Statement

This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

IBG Indiana Botanic Gardens

Storage

Store in a dry, cool place.

General

C-104918

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Blueberry Leaf Extract 60 mg by Botanic Choice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Blueberry Leaf Extract 60 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Blueberry Leaf Extract 60 mg by Botanic Choice

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Blueberry extract

Interacts with
88 drugs
180 mg per serving Form: Chlorogenic Acid

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...

Blueberry extract monograph & interactions

Other (inactive) ingredients: Gelatin, Soybean Oil, Vegetable Glycerin, Soy Lecithin, Yellow Beeswax, Caramel, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blueberry Leaf Extract 60 mg by Botanic Choice Drug Interactions

Want to check YOUR meds against Blueberry Leaf Extract 60 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
88Drugs
88 Minor

Ingredients driving the most interactions

Blueberry extract 88

Individual Drug Interactions

The ingredients in Blueberry Leaf Extract 60 mg interact with 88 drugs. Click any drug to see the details.

1 of the 1 ingredient in Blueberry Leaf Extract 60 mg interact with drugs. Each result below shows which ingredient is responsible. Blueberry extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Blueberry Leaf Extract 60 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blueberry extract3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
Blueberry extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Blueberry Leaf Extract 60 mg, from the product label.

Botanic Choice

See all Botanic Choice products
Name
Indiana Botanic Gardens, Inc.
Street Address
3401 W. 37th Ave.
City
Hobart
State
IN
ZipCode
46342
Phone Number
1-800-644-8327
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Blueberry Leaf Extract 60 mg by Botanic Choice: Common Questions

Does Blueberry Leaf Extract 60 mg by Botanic Choice interact with any medications?
Yes. Based on its ingredients, Blueberry Leaf Extract 60 mg has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blueberry Leaf Extract 60 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on diabetes medication?
Blueberry extract may theoretically lower blood sugar further, raising the risk of hypoglycemia. Talk to your doctor or pharmacist before adding it if you take antidiabetes drugs — they can help you decide whether it's safe for you and whether you need any adjustments to monitoring.
What are the side effects?
Blueberry extract is generally well tolerated. Freeze-dried blueberries in particular may cause constipation, diarrhea, nausea, or vomiting — in one trial, about a quarter of people taking a high dose stopped because of stomach upset in the first week.
Is it safe during pregnancy?
Blueberry extract is rated likely safe in pregnancy, though concentrated supplements haven't been well studied. If you're pregnant, confirm with your doctor or pharmacist whether this product is right for you.
Will this really help my blood pressure?
The evidence rates blueberry extract as possibly ineffective for hypertension, so it's unlikely to be a reliable tool for blood pressure control on its own.
What exactly is in this softgel?
Each capsule contains 60 mg of blueberry extract in a softgel made with gelatin, soybean oil, vegetable glycerin, soy lecithin, beeswax, caramel, and water. If you're allergic to soy or gelatin, check the label carefully.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blueberry Leaf Extract 60 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blueberry Leaf Extract 60 mg label
Go deeper

The Full Monographs Behind Blueberry Leaf Extract 60 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blueberry

Interacts with 88 drugs

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...

Read the full Blueberry monograph →
Sources

Sources & How We Checked

Blueberry Leaf Extract 60 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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