Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Bone, Beauty & Hormone Formula Ingredients & Drug Interactions

by GNC Women's Ultra Mega

Bone, Beauty & Hormone Formula label
See full label image
Softgel Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bone, Beauty & Hormone Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bone, Beauty & Hormone Formula is a dietary supplement by GNC Women's Ultra Mega with 3 active ingredients. Its ingredients are commonly taken for skin conditions like acne and eczema, digestive support, diuretic ('detox') and blood purifier.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Burdock root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bone, Beauty & Hormone Formula by GNC Women's Ultra Mega

Ask about any prescription or over-the-counter medication and we check it for interactions with Bone, Beauty & Hormone Formula by GNC Women's Ultra Mega — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bone, Beauty & Hormone Formula by GNC Women's Ultra Mega

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This formula has three active ingredients. Burdock root extract is included for general wellness support.

Gamma-linolenic acid is an omega-6 fatty acid thought to support skin and hormone health. MBP (milk basic protein) is a dairy-derived component marketed for bone support.

The capsules are made from gelatin and softened with safflower oil, glycerin, and colorants.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Burdock product and its label doesn't state a use — see Burdock's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that burdock root extract works for acne, aging skin, breast cancer prevention, colds, or eczema — the data simply isn't reliable enough to say either way. The same goes for gamma-linolenic acid and MBP; effectiveness ratings for those aren't on file.

If you're considering this product for a specific concern, talk it over with your doctor or pharmacist about what the broader evidence shows.

The evidence, ingredient by ingredient Burdock

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Burdock is generally well tolerated when eaten as food, and it's been used safely in traditional medicine for a long time. Short-term use in healthy adults is considered likely safe, though human safety studies are limited.

You should avoid medicinal amounts of burdock during pregnancy because of a lack of safety data and possible effects on the uterus, and avoid it while breastfeeding due to insufficient safety information. Allergic reactions including contact dermatitis are rare but possible, and a single case of liver injury has been reported with a burdock-containing supplement — though it's unclear if burdock alone was responsible.

Side effects, ingredient by ingredient Burdock

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Burdock.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take a blood thinner or antiplatelet drug — including warfarin, aspirin, clopidogrel, or similar medications — check with your doctor or pharmacist before starting this product, as burdock may increase bleeding risk. The other ingredients haven't been checked against medications in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a bone-and-hormone support blend best suited for people looking for general wellness support who don't take blood thinners. If you're on a blood thinner or antiplatelet drug, check with your doctor or pharmacist before starting.

Pregnant and breastfeeding people should avoid medicinal doses of burdock. Run your medications through the checker on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bone, Beauty & Hormone Formula, straight from the product label.

Brand GNC Women's Ultra Mega
Net contents 30 Pack(s)
Market status On market
Date entered into DSLD Jan 25, 2017
DSLD ID 69502
Product type Botanical With Nutrients
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bone, Beauty & Hormone Formula by GNC Women's Ultra Mega, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Reddish-Orange Softgel(s)
Maximum serving Sizes:
1 Reddish-Orange Softgel(s)
IngredientAmount% DV
Calories5 Calorie(s)--
Calories from Fat5 Calorie(s)--
Gamma-Linolenic Acid250 mg--
Total Fat0.5 Gram(s)1%
MBP40 mg--
Burdock root extract100 mg--

Other ingredients: Safflower Oil, Gelatin, Glycerin, Annatto color, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

CODE 204611 GQG

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take the contents of one pack daily with food. For maximum benefits, take as directed every day.

General Statements

Each pack contains: Bone, Beauty & Hormone Formula

Physician endorsed This product is endorsed by the GNC Medical Advisory Board. This team of esteemed physicians utilizes their extensive medical knowledge and experience to aid in the creation of GNC premium products, helping you to achieve optimal health through comprehensive nutritional support so you can live your best life!

Achieve your daily nutritional goals with customized ingredients plus multivitamins that have more antioxidant power than ever, contain over 30 clinically studied ingredients - and are smaller and easier to swallow.

Targets 13 core functions for head-to-toe support

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blends for six weeks experienced significant improvements in serum levels of certain key nutrients compared to a placebo and a basic multivitamin formula based upon multivariate statistical analyses of a group of B vitamins (thiamin, niacin, riboflavin, pantothenic acid, biotin, folic acid and vitamins B-6 and B-12) and key antioxidants and carotenoids (a group of beta-carotene, alpha-tocopherol, selenium, lutein and lycopene). Statistical improvements in SF-36 vitality and mental health scores were also observed compared to placebo.

Conforms to USP <2091> for weight. Meet USP <2040> disintegration.

Formula

Contains: Milk and Soybeans.

Skin health Biotin and GLA for beautiful, healthy skin

Hormonal balance GLA to help regulate body processes and hormonal balance

Bone health Clinically proven MBP plus Vitamin D and calcium for healthy bones

Precautions

Contains: Milk and Soybeans.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Keep out of reach of children.

Seals/Symbols

Actual Size

MBP.

Physician endorsed

Formulation

No artificial colors, no artificial flavors, yeast free.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

MBP is registered in the U.S.A. by Megamilk snow brand Co., LTD.

Vitapak program with clinically studied multivitamin

Our most comprehensive Vitapak program that provides support for both wellness and performance

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bone, Beauty & Hormone Formula by GNC Women's Ultra Mega label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bone, Beauty & Hormone Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bone, Beauty & Hormone Formula by GNC Women's Ultra Mega

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Reddish-Orange Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Gamma-Linolenic Acid

250 mg per serving

MBP

40 mg per serving

Burdock root extract

Interacts with
122 drugs
100 mg per serving

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and mo...

Burdock root extract monograph & interactions

Other (inactive) ingredients: Safflower Oil, Gelatin, Glycerin, Annatto color, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bone, Beauty & Hormone Formula by GNC Women's Ultra Mega Drug Interactions

Want to check YOUR meds against Bone, Beauty & Hormone Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Burdock root extract 122

Individual Drug Interactions

The ingredients in Bone, Beauty & Hormone Formula interact with 122 drugs. Click any drug to see the details.

1 of the 3 ingredients in Bone, Beauty & Hormone Formula interact with drugs. Each result below shows which ingredient is responsible. Burdock root extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Bone, Beauty & Hormone Formula with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Burdock root extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Burdock root extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bone, Beauty & Hormone Formula, from the product label.

GNC Women's Ultra Mega

See all GNC Women's Ultra Mega products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Bone, Beauty & Hormone Formula by GNC Women's Ultra Mega: Common Questions

Does Bone, Beauty & Hormone Formula by GNC Women's Ultra Mega interact with any medications?
Yes. Based on its ingredients, Bone, Beauty & Hormone Formula has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bone, Beauty & Hormone Formula contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
You should avoid medicinal amounts of burdock during pregnancy because of a lack of safety data and possible effects on the uterus. Talk with your doctor or pharmacist about whether this product is right for you.
Is it safe while breastfeeding?
There isn't enough safety information to use medicinal amounts of burdock while breastfeeding. Check with your doctor or pharmacist for personalized advice.
What does gamma-linolenic acid do?
Gamma-linolenic acid is an omega-6 fatty acid included in this formula for skin and hormone support, though we don't have effectiveness ratings for it on file.
Does burdock root actually work for skin or bones?
The evidence we hold doesn't establish that burdock root is effective for acne, aging skin, eczema, or the other conditions listed on this product. The data simply isn't reliable enough to say either way.
What are the side effects of burdock?
Burdock is well tolerated when eaten as food, and serious side effects are rare. Allergic reactions including contact dermatitis can occur, especially with prolonged skin use. A single case of liver injury has been reported with a burdock-containing supplement, though it's unclear if burdock alone was responsible.
Are there any fillers in this?
Yes — the capsules contain safflower oil, glycerin, annatto color, and titanium dioxide as inactive ingredients alongside the three active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bone, Beauty & Hormone Formula is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bone, Beauty & Hormone Formula label
Go deeper

The Full Monographs Behind Bone, Beauty & Hormone Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Burdock

Interacts with 122 drugs

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...

Read the full Burdock monograph →
Sources

Sources & How We Checked

Bone, Beauty & Hormone Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Burdock 11 references
  1. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  2. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
  3. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
  5. Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. DOI
  6. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254. PubMed
  7. Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
  8. Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157. DOI
  9. <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p> DOI
  10. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
  11. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed

See these in context on the Burdock monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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