Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Brain Fuel Ingredients & Drug Interactions

by Om Mushroom Superfood

Brain Fuel label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Brain Fuel against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Brain Fuel is a dietary supplement by Om Mushroom Superfood with 3 active ingredients. Its ingredients are commonly taken for memory and cognitive support, nerve health, mood and anxiety.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lion's Mane, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Brain Fuel by Om Mushroom Superfood

Ask about any prescription or over-the-counter medication and we check it for interactions with Brain Fuel by Om Mushroom Superfood — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Brain Fuel by Om Mushroom Superfood

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Certified Organic Mushroom Powder Blend” is a proprietary blend — the label gives one combined amount (2 Gram(s)) without saying how much of each component you get.

Brain Fuel contains three active ingredients: Folate (a B vitamin), a Certified Organic Mushroom Powder Blend, and Lion's Mane mushroom powder. The product also includes two inactive ingredients — vegetable cellulose (the capsule) and myceliated oats (a binder).

Lion's Mane and the mushroom blend make up the core of this formula.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lion's Mane Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: mental clarity focus alertness.
  • We looked for evidence on: Cognitive function, Memory, Cognitive impairment, Anxiety, alertness, mental acuity.
  • The closest evidence on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Cognitive impairment, Memory.

The evidence for Lion's Mane isn't established yet in the data we hold. Studies have rated it as having insufficient reliable evidence for Alzheimer disease, anxiety, athletic performance, cancer, cognitive function, and cognitive impairment.

That doesn't mean it doesn't work — it means the research so far isn't robust enough to say either way. For Folate and Reishi, effectiveness information isn't on file.

The evidence, ingredient by ingredient Lion's Mane Mushroom

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lion's Mane is generally well tolerated as a food, but long-term supplement safety hasn't been studied thoroughly. The most common side effects reported orally are gastrointestinal discomfort, nausea, and skin rash.

Because there isn't enough safety data, the facts advise against using it during pregnancy or while breastfeeding — talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Lion's Mane Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Brain Fuel, double-check these with your pharmacist or doctor: blood thinners and antiplatelet drugs (Moderate risk of increased bleeding), diabetes medications (Moderate risk of added blood-sugar-lowering effect), and immunosuppressants (Moderate risk of interference with immune suppression). No interactions are documented for the Folate or Reishi in this product in the data we hold.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Brain Fuel is built around Lion's Mane mushroom, which has shown promise in some areas but lacks solid evidence in the research we hold. The main concern is interaction with blood thinners, diabetes medications, and immunosuppressants — so check your medications first.

If you take any of those drug types or you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Brain Fuel, straight from the product label.

Brand Om Mushroom Superfood
Barcode (UPC) 856210008196
Net contents 90 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2022
DSLD ID 271714
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Brain Fuel by Om Mushroom Superfood, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
856210008196
IngredientAmount% DV
Folate800 mcg DFE200%
Certified Organic Mushroom Powder Blend2 Gram(s)--
Lion's Mane, Powder0 NP--
Reishi, Powder0 NP--

Other ingredients: Vegetable Cellulose, myceliated Oats

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Mental Clarity Focus & Alertness

We grow our OM. We grow a diverse range of mushroom species at our indoor farm in California and capture the complete nutritional value of the growing cycle. Whole food mushrooms are important because they provide a full spectrum of active compounds to support optimal health. Whole Food Nutrition Tested for Heavy Meals

Non GMO Project Verified Gluten Free

Vegan

Formula

The Smart Mushroom Superfood. Calm your mind and spark clarity with an expertly curated blend of Lion's Mane and Reishi, plus Folate, one of the body's key building blocks.

Powered by Lion's Mane + Folate Mushroom superfood daily boost capsules

Certified Kosher by Earth Kosher

KETO Keto-Friendly PF Paleo-Friendly

Beta Glucans and Prebiotics Om grown mushroom blend 2,000 mg per serving See supplement facts

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Non GMO Project Verified nongmoproject.org

USA Grown Mushrooms

EarthKosher

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take three (3) capsules per day with a glass of water.

Precautions

Take as directed.

If you have a medical condition, are on medication or are pregnant or nursing, please seek the direction of a qualified health care professional before using.

Keep out of the reach of children.

Storage

Store in a cool, dry place.

General Statements

Facebook Instagram @OmMushrooms OmMushrooms.com

Scan code to learn more 30 day supply

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Brain Fuel by Om Mushroom Superfood label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Brain Fuel label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Brain Fuel by Om Mushroom Superfood

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Folate

800 mcg DFE per serving Form: Folic Acid

Certified Organic Mushroom Powder Blend

2 Gram(s) per serving

Other (inactive) ingredients: Vegetable Cellulose, Myceliated Oats. These complete the product’s ingredient list but are not active constituents.

Interaction report

Brain Fuel by Om Mushroom Superfood Drug Interactions

Want to check YOUR meds against Brain Fuel?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Lion's Mane, Powder 327

Individual Drug Interactions

The ingredients in Brain Fuel interact with 327 drugs. Click any drug to see the details.

1 of the 3 ingredients in Brain Fuel interact with drugs. Each result below shows which ingredient is responsible. Lion's Mane, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Brain Fuel with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lion's Mane, Powder3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
Lion's Mane, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Brain Fuel, from the product label.

Om Mushroom Superfood

See all Om Mushroom Superfood products
Name
M2 Ingredients
City
Carlsbad
State
CA
ZipCode
92008
Pharmacist Counseling Corner

Brain Fuel by Om Mushroom Superfood: Common Questions

Does Brain Fuel by Om Mushroom Superfood interact with any medications?
Yes. Based on its ingredients, Brain Fuel has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Brain Fuel contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Lion's Mane mushroom supposed to do?
Lion's Mane is marketed for cognitive support and brain health, but the evidence we hold shows insufficient data to reliably rate it for Alzheimer disease, anxiety, cognitive function, cognitive impairment, athletic performance, or cancer. Talk with your doctor about whether it's a fit for what you're hoping to address.
Can I take Brain Fuel if I'm pregnant or breastfeeding?
The safety data advises against it — there isn't enough information to know it's safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist about your options if you're in either situation.
What side effects might I have from Lion's Mane?
The most common ones are gastrointestinal discomfort, nausea, and skin rash. Most people tolerate it well, but long-term safety hasn't been thoroughly studied as a supplement.
Does this have any fillers or extra stuff?
The active ingredients are Folate, the Certified Organic Mushroom Powder Blend, and Lion's Mane powder. The inactive ingredients are vegetable cellulose (the capsule itself) and myceliated oats, which help hold the formula together.
I take warfarin for blood clots. Can I use Brain Fuel?
Lion's Mane in this product may theoretically increase bleeding risk with warfarin and other blood thinners. Check with your doctor or pharmacist before starting — don't combine them without their okay.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Brain Fuel is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Brain Fuel label
Go deeper

The Full Monographs Behind Brain Fuel’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lion's Mane Mushroom

Interacts with 327 drugs

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...

Read the full Lion's Mane Mushroom monograph →
Sources

Sources & How We Checked

Brain Fuel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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