Major interaction on record — check this product against your medications before combining. Based on 5 of 10 ingredients. Check your meds →
Dietary supplement

Breast Protect Plus Ingredients & Drug Interactions

by True Botanica

Breast Protect Plus label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Breast Protect Plus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Breast Protect Plus is a dietary supplement by True Botanica with 10 active ingredients. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 528 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Broccoli Bud, Stem Extract, Apatite, Total Tocotrienols. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Breast Protect Plus by True Botanica

Ask about any prescription or over-the-counter medication and we check it for interactions with Breast Protect Plus by True Botanica — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Breast Protect Plus by True Botanica

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 3 of its 10 active ingredients.
  • “DeltaGold Mixed Tocotrienols” is listed as a grouped ingredient — the label gives one combined amount (250 mg) without saying how much of each component you get.
  • “Trace Minerals Pentas BrP Mix” is listed as a grouped ingredient — the label gives one combined amount (10 mg) without saying how much of each component you get.

Breast Protect Plus contains 10 ingredients total. The active components include Inulin (a fiber that may support blood sugar and digestive health), Sulfur (a mineral), Broccoli Bud and Stem Extract (rich in plant compounds), Total Tocotrienols (a form of vitamin E), and Apatite (a mineral source containing calcium).

The product also contains several other ingredients we were unable to verify: HMRLignan, Slate, Porphyry, Dioptase, and Topaz. The inactive ingredients—Brown Rice Flour, Cellulose, Magnesium Stearate, Silicon Dioxide, and Chlorophyll—are fillers and binders that hold the capsule together.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: supports breast tissue health and hormonal balance.
  • We looked for evidence on: Breast cancer, Menopausal symptoms, Postmenopausal conditions, Breast health, Hormonal balance, Estrogen metabolism.
  • The closest evidence on file: Calcium is rated "Possibly Ineffective" for Breast cancer (Natural Medicines).
  • Also on file: Inulin is rated "Insufficient Reliable Evidence To Rate" for Menopausal symptoms.
  • Also on file: Broccoli is rated "Insufficient Reliable Evidence To Rate" for Breast cancer.

The evidence for Breast Protect Plus's ingredients is mixed. Inulin is possibly effective for obesity, constipation, and diabetes support.

Sulfur is possibly effective for scabies and dandruff. Broccoli extract is possibly effective for colorectal cancer prevention.

Tocotrienols are possibly effective for diabetes support, though they appear possibly ineffective for high cholesterol. For several conditions the ingredients may address—such as breast cancer or fibromyalgia—the evidence is insufficient to establish effectiveness.

We hold no effectiveness data for Slate, Porphyry, HMRLignan, Dioptase, or Topaz.

The evidence, ingredient by ingredient Broccoli Tocotrienols Inulin Sulfur Calcium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inulin is generally well tolerated but commonly causes gas, bloating, diarrhea, and stomach cramps, especially at higher doses—start low and increase gradually. Sulfur taken by mouth can cause diarrhea and, in rare cases with very high doses, metabolic acidosis.

Broccoli extract may cause loose stools, diarrhea, and abdominal pain at high doses. Tocotrienols are generally well tolerated in studies; no adverse effects were reported in clinical trials, though topical forms may cause mild itching.

For pregnancy and breastfeeding: Inulin is likely safe. Sulfur is possibly safe.

Broccoli is likely safe. Tocotrienols carry insufficient safety data during pregnancy, so the facts recommend avoiding supplemental doses; breastfeeding safety is also unclear, so check with your doctor.

Apatite (calcium) is likely safe in pregnancy and possibly unsafe in breastfeeding—talk to your provider about appropriate amounts.

Side effects, ingredient by ingredient Broccoli Tocotrienols Inulin Sulfur Calcium

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Calcium, Inulin, Broccoli, Tocotrienols.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 528 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check if you're on dolutegravir or elvitegravir (HIV drugs)—calcium in this product requires separation by 2-6 hours. Also check levothyroxine (thyroid), sotalol (heart rhythm), raltegravir (HIV), diltiazem (blood pressure), or calcipotriene (psoriasis)—calcium timing matters here too.

If you take ceftriaxone intravenously, avoid this product entirely. Finally, if you're on any drug metabolized by CYP1A2 or CYP2A6 liver enzymes, or on blood thinners or antidiabetes medications, ask your pharmacist about the broccoli and inulin content.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you take HIV medications (dolutegravir, elvitegravir, raltegravir), thyroid medication, heart rhythm drugs, or blood thinners, you'll need to check this product with your pharmacist first—some ingredients can significantly reduce how well these drugs work or increase bleeding risk. Otherwise, this may be worth considering if you're interested in broccoli and mineral supplementation, though be prepared for possible digestive effects from the inulin.

Talk to your pharmacist before starting, especially if you're on any prescription medication.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Breast Protect Plus, straight from the product label.

Brand True Botanica
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336210
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Breast Protect Plus by True Botanica, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Inulin0 NP--
Sulfur0 NP--
Slate0 NP--
Porphyry0 NP--
Broccoli Bud, Stem Extract300 mg--
DeltaGold Mixed Tocotrienols250 mg--
Total Tocotrienols75.25 mg--
HMRLignan40 mg--
Trace Minerals Pentas BrP Mix10 mg--
Dioptase0 NP--
Topaz0 NP--
Apatite0 NP--

Other ingredients: Brown Rice Flour, Cellulose, Magnesium Stearate, Silicon Dioxide, Chlorophyll

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

This formulation significantly supports the ongoing health of breast tissue. Also promotes liver detoxification, healthy hormonal balance and healthy hair growth.

Contains no milk, eggs, fish, Crustacean shellfish, tree nuts, peanuts, soy, wheat, or sesame.

Vegetarian capsules.

Precautions

Consult your health care provider before using this product if you are pregnant, lactating or have other medical concerns or compatibility issues.

Do not use this product if allergies to the listed ingredients are known to exist or if any adverse effects result after taking the first dose.

This product contains a desiccant package, which should not be eaten. Keep desiccant in the bottle until all capsules have been taken.

Keep out of the reach of children.

Brand IP Statement(s)

HMRlignan trademark is used under license from Linnea SATM. DeltaGold is a registered trademark of American River Nutrition, Inc.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Usage: Two capsules daily, or as suggested by your health care provider.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Breast Protect Plus by True Botanica label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Breast Protect Plus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Breast Protect Plus by True Botanica

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Broccoli Bud, Stem Extract

Interacts with
187 drugs
300 mg per serving Form: Broccoli Bud Extract, Broccoli Stem Extract

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Broccoli Bud, Stem Extract monograph & interactions

DeltaGold Mixed Tocotrienols

250 mg per serving

HMRLignan

40 mg per serving Form: 7-Hydroxymatairesinol

Trace Minerals Pentas BrP Mix

10 mg per serving

Other (inactive) ingredients: Brown Rice Flour, Cellulose, Magnesium Stearate, Silicon Dioxide, Chlorophyll. These complete the product’s ingredient list but are not active constituents.

Interaction report

Breast Protect Plus by True Botanica Drug Interactions

Want to check YOUR meds against Breast Protect Plus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
528Drugs
7 Major 326 Moderate 195 Minor

Ingredients driving the most interactions

Broccoli Bud, Stem Extract 187
Apatite 168
Total Tocotrienols 122
Inulin 86

Individual Drug Interactions

The ingredients in Breast Protect Plus interact with 528 drugs. Click any drug to see the details.

4 of the 10 ingredients in Breast Protect Plus interact with drugs. Each result below shows which ingredient is responsible. Broccoli Bud, Stem Extract Apatite Total Tocotrienols Inulin

Each ingredient & the kinds of drugs it affects

For each ingredient in Breast Protect Plus with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Broccoli Bud, Stem Extract2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Broccoli Bud, Stem Extract full monograph & interactions

Apatite18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Apatite full monograph & interactions

Total Tocotrienols1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Concomitant use of tocotrienols with anticoagulant or antiplatelet agents might increase the risk of bleeding. However, this has not been reported in humans.
Taking tocotrienols orally inhibits experimentally-induced platelet aggregation in humans. Theoretically tocotrienols might increase the risk of bleeding if taken with antiplatelet or anticoagulant drugs. However, tocotrienols 400-800 mg daily have been used with aspirin and/or clopidogrel for 1 year with no clear cumulative antiplatelet effects and no reports of bleeding.

Likelihood Unlikely Evidence B
Total Tocotrienols full monograph & interactions

Inulin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.

Likelihood Unlikely Evidence D
Inulin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Breast Protect Plus, from the product label.

True Botanica

See all True Botanica products
Name
True Botanica, LLC
Street Address
1005 Richards Road, Suite D
City
Hartland
State
WI
ZipCode
53029
Phone Number
1-800-315-8783
Web Address
www.truebotanica.com
Pharmacist Counseling Corner

Breast Protect Plus by True Botanica: Common Questions

Does Breast Protect Plus by True Botanica interact with any medications?
Yes. Based on its ingredients, Breast Protect Plus has a known interaction with 528 medications, including 7 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Breast Protect Plus contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this product stop my thyroid medication from working?
Possibly, if you take levothyroxine. Calcium in this product can reduce how much of your thyroid drug your body absorbs. Take your thyroid medication at least 4 hours apart from this supplement—morning and evening doses work well. Your pharmacist can help you schedule them.
What's inulin, and why does it make me gassy?
Inulin is a fiber from plants that feeds good bacteria in your gut—that's partly why it's here. Those bacteria produce gas as they digest it, which is why many people feel bloated or gassy, especially when they first start. Starting with a smaller amount and building up usually helps.
Is this safe to take while I'm pregnant?
Most ingredients are likely or possibly safe in pregnancy—inulin, sulfur, and broccoli are fine. But tocotrienols don't have enough safety data, so the facts recommend avoiding them during pregnancy. Talk to your doctor or pharmacist about whether this product is right for you right now.
Can I take this with blood thinners like warfarin?
Tocotrienols in this product theoretically increase bleeding risk with blood thinners, though it hasn't been seen in people yet. You should still check with your pharmacist before starting—don't skip this one.
What's the calcium dose in here?
The product facts don't specify how much calcium (from Apatite) is in each capsule, so I can't tell you the exact amount. Ask the brand or check the label, especially if you're already taking calcium supplements or taking medications that interact with calcium.
Will this help prevent breast cancer?
The evidence isn't there yet. Broccoli has been studied for colorectal cancer with possibly effective evidence, but for breast cancer the data is too thin to say. This product isn't proven for cancer prevention.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Breast Protect Plus label
Go deeper

The Full Monographs Behind Breast Protect Plus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph → Herb & supplement monograph

Tocotrienols

Interacts with 122 drugs

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early research is interesting but far from conclusi...

Read the full Tocotrienols monograph → Herb & supplement monograph

Inulin

Interacts with 86 drugs

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements and processed foods. It may help with regu...

Read the full Inulin monograph → Herb & supplement monograph

Sulfur

Sulfur is a mineral used mainly in topical skin products for acne, rosacea, dandruff, and certain skin infections, and has a long history in dermatology. Topical sulfur is generally well tol...

Read the full Sulfur monograph → Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph →
Sources

Sources & How We Checked

Breast Protect Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 105 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inulin 17 references
  1. Williams CM. Effects of inulin on lipid parameters in humans. J Nutr 1999 Jul;129(7 Suppl):1471S-3S. PubMed
  2. Pedersen A, Sandstrom B, Van Amelsvoort JM. The effect of ingestion of inulin on blood lipids and gastrointestinal symptoms in healthy females. Br J Nutr 1997;78:215-22. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
  5. Dehghan P, Gargari BP, Jafar-Abadi MA, Aliasgharzadeh A. Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial. Int J Food Sci Nutr 2014;65(1):117-23. PubMed
  6. Guess ND, Dornhorst A, Oliver N, Frost GS. A randomised crossover trial: the effect of inulin on glucose homeostasis in subtypes of prediabetes. Ann Nutr Metab 2016;68(1):26-34. PubMed
  7. Marteau P, Jacobs H, Cazaubiel M, Signoret C, Prevel JM, Housez B. Effects of chicory inulin in constipated elderly people: a double-blind controlled trial. Int J Food Sci Nutr 2011;62(2):164-70. PubMed
  8. Mensink MA, Frijlink HW, van der Voort Maarschalk K, Hinrichs WL. Inulin, a flexible oligosaccharide I: review of its physicochemical characteristics. Carbohydr Polym 2015;130:405-19. PubMed
  9. Slavin J, Feirtag J. Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects. Food Funct. 2011;2(1):72-7. PubMed
  10. Micka A, Siepelmeyer A, Holz A, Theis S, Schön C. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr. 2017;68(1):82-89. PubMed
  11. Smiljanec K, Mitchell CM, Privitera OF, Neilson AP, Davy KP, Davy BM. Pre-meal inulin consumption does not affect acute energy intake in overweight and obese middle-aged and older adults: A randomized controlled crossover pilot trial. Nutr Health. 2017;23 PubMed
  12. Cai X, Yu H, Liu L, et al. Milk powder co-supplemented with inulin and resistant dextrin improves glycemic control and insulin resistance in elderly type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial. Mol Nutr Food Res PubMed
  13. Rao M, Gao C, Xu L, et al. Effect of inulin-type carbohydrates on insulin resistance in patients with type 2 diabetes and obesity: a systematic review and meta-analysis. J Diabetes Res. 2019;2019:5101423. PubMed
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Broccoli 5 references
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Tocotrienols 4 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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