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Dietary supplement

Bugleweed Ingredients & Drug Interactions

by Herb Pharm

Bugleweed label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bugleweed against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bugleweed is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for mild overactive thyroid symptoms, heart palpitations and rapid heartbeat, anxiety and restlessness.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bugleweed Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bugleweed by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Bugleweed by Herb Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bugleweed by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: bugleweed liquid extract. The extract is prepared using certified organic grain alcohol, distilled water, and vegetable glycerine as the carrier base, with bugleweed extractives as the source material.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Bugleweed's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports healthy thyroid and nervous system function.
  • We looked for evidence on: Hyperthyroidism, Premenstrual syndrome (PMS), tachycardia, anxiety.
  • The closest evidence on file: Bugleweed is rated "Insufficient Reliable Evidence To Rate" for Hyperthyroidism (Natural Medicines).
  • Also on file: Bugleweed is rated "Insufficient Reliable Evidence To Rate" for Premenstrual syndrome (PMS).

The evidence we hold on bugleweed's effectiveness is insufficient. We don't have reliable data to rate whether it works for hyperthyroidism, insomnia, or premenstrual syndrome (PMS) — the conditions it's traditionally used for.

That doesn't mean it doesn't work; it means the studies we have access to don't establish it clearly enough for us to make a claim.

The evidence, ingredient by ingredient Bugleweed

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bugleweed is not recommended in pregnancy — the safety data advises against it due to possible hormone effects. While breastfeeding, it's possibly unsafe because bugleweed may lower prolactin and reduce milk supply.

Because this product can affect thyroid function, use it only under the guidance of a healthcare provider. No adverse effects were reported in the data we hold, but that doesn't guarantee you won't experience any.

Side effects, ingredient by ingredient Bugleweed

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bugleweed.
  • The most serious interaction on file is rated Moderate.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take thyroid hormone replacement (for an underactive or overactive thyroid), check your exact medication with the tool below before starting bugleweed — it may reduce how well your thyroid medicine works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

If you're curious about bugleweed for thyroid support or another reason, talk to your doctor or pharmacist first — especially if you take thyroid medication or are pregnant or breastfeeding. Anyone with a thyroid condition should get personalized advice before adding this to their routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bugleweed, straight from the product label.

Brand Herb Pharm
Net contents 8 fl. Oz.
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 23110
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bugleweed by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
30 Drop(s)
Maximum serving Sizes:
40 Drop(s)
IngredientAmount% DV
Bugleweed Liquid Extract0 NP--

Other ingredients: certified organic grain Alcohol, distilled Water, Vegetable Glycerine, Bugleweed extractives

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

We prepare our Bugleweed Extract from the flowering aerial parts of Lycopus spp. plants which are Certified Organically Grown on our own farm or are Custom Wildcrafted(TM) in their natural wild habitat. To assure optimal extraction of Bugleweed's bioactive compounds, the herb is hand-harvested while in full flower, is carefully shade-dried, and is then thoroughly extracted.

401854-1M48

LIQUID HERBAL EXTRACT

FDA Statement of Identity

HERBAL SUPPLEMENT

Suggested/Recommended/Usage/Directions

SUGGESTED USE Shake Well Before using Two to four times per day take 30 to 40 drops in a little water.

Shake Well Before Dispensing From This Bottle

Precautions

Caution: Consult a qualified midwife or physician before taking during pregnancy.

Keep Out of the Reach of Children

General

007

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bugleweed by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bugleweed label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bugleweed by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size30 Drop(s) Dosage formLiquid Amounts shown are per serving.

Bugleweed Liquid Extract

Interacts with
16 drugs
0 NP per serving

Bugleweed is a traditional herb most often used for mild overactive thyroid symptoms and the rapid heartbeat that can come with it, but high-quality h...

Bugleweed Liquid Extract monograph & interactions

Other (inactive) ingredients: Certified organic grain Alcohol, Distilled Water, Vegetable Glycerine, Bugleweed extractives. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bugleweed by Herb Pharm Drug Interactions

Want to check YOUR meds against Bugleweed?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Moderate

Ingredients driving the most interactions

Bugleweed Liquid Extract 16

Individual Drug Interactions

The ingredients in Bugleweed interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Bugleweed interact with drugs. Each result below shows which ingredient is responsible. Bugleweed Liquid Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Bugleweed with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bugleweed Liquid Extract1 drug type · 16 drugs

Thyroid Hormone

Theoretically, bugleweed may alter thyroid function.
Concomitant use of bugleweed may reduce the effects of thyroid hormones by blocking peripheral conversion of thyroxine (T4) to triiodothyronine (T3).

Likelihood Probable Evidence D
Bugleweed Liquid Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bugleweed, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Bugleweed by Herb Pharm: Common Questions

Does Bugleweed by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Bugleweed has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bugleweed contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
No, the safety data advises against bugleweed during pregnancy. Talk with your doctor before considering it if you're pregnant or planning to become pregnant.
Is it safe while breastfeeding?
Bugleweed is possibly unsafe while breastfeeding because it may lower prolactin levels and reduce milk production. It's best avoided if you're nursing — check with your doctor or pharmacist.
Does bugleweed actually work for hyperthyroidism?
The evidence we have is insufficient to say whether it works. That's why using it only under a healthcare provider's guidance is so important — they can monitor whether it's helping your specific situation.
What does bugleweed actually do in the body?
Bugleweed may affect how your body converts thyroid hormone into its active form and can influence thyroid function overall. That's why medical supervision is necessary if you use it.
What's in the liquid besides the active ingredient?
The extract is suspended in certified organic grain alcohol, distilled water, and vegetable glycerine. These are the carriers that keep the bugleweed extractives in solution.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bugleweed is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bugleweed label
Go deeper

The Full Monographs Behind Bugleweed’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bugleweed

Interacts with 16 drugs

Bugleweed is a traditional herb most often used for mild overactive thyroid symptoms and the rapid heartbeat that can come with it, but high-quality human evidence is very limited. Because i...

Read the full Bugleweed monograph →
Sources

Sources & How We Checked

Bugleweed's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bugleweed 4 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Bugleweed monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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