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Dietary supplement

Bugleweed Ingredients & Drug Interactions

by Herbs Etc.

Bugleweed label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bugleweed against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bugleweed is a dietary supplement by Herbs Etc. with 1 active ingredient. Its ingredients are commonly taken for mild overactive thyroid symptoms, heart palpitations and rapid heartbeat, anxiety and restlessness.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are fresh Bugleweed. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bugleweed by Herbs Etc.

Ask about any prescription or over-the-counter medication and we check it for interactions with Bugleweed by Herbs Etc. — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Bugleweed by Herbs Etc.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: fresh bugleweed. It's prepared as a liquid extract with 40% grain alcohol and purified water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Bugleweed product and its label doesn't state a use — see Bugleweed's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for bugleweed isn't established in our data. Effectiveness ratings for hyperthyroidism, insomnia, and premenstrual syndrome (PMS) all show insufficient reliable evidence.

That doesn't mean it doesn't work — it means the research we have on file isn't strong enough to say either way.

The evidence, ingredient by ingredient Bugleweed

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bugleweed should only be used under the guidance of a healthcare provider because of its effects on thyroid function. The safety data advises against it during pregnancy.

Additionally, bugleweed may reduce prolactin and milk production, so it should not be used while breastfeeding. No adverse effects were reported in our data, but that's not the same as a clean safety profile — thyroid function itself is the main concern here.

Side effects, ingredient by ingredient Bugleweed

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bugleweed.
  • The most serious interaction on file is rated Moderate.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any thyroid hormones (levothyroxine, liothyronine, desiccated thyroid, or combination thyroid products) with your pharmacist before starting bugleweed. The interaction is Moderate, and it could reduce how well your medication works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

If you're considering bugleweed for thyroid support, talk to your doctor or pharmacist first — especially if you're already on thyroid medication. It's not safe in pregnancy or while nursing.

The biggest thing: don't combine it with thyroid drugs without checking in.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bugleweed, straight from the product label.

Brand Herbs Etc.
Net contents 8 Fluid Ounce(s); 236 mL
Market status On market
Date entered into DSLD Sep 25, 2015
DSLD ID 50190
Product type Botanical
Supplement form Liquid
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bugleweed by Herbs Etc., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0 Not Present
Maximum serving Sizes:
0 Not Present
IngredientAmount% DV
fresh Bugleweed0 NP--

Other ingredients: 40% Grain Alcohol, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Herbal Single

Professional Strength

99029

For dispensing purposes only

Formula

Fresh herb extract

Lycopus virginicus

FDA Statement of Identity

Fast-Acting dietary supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bugleweed by Herbs Etc. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bugleweed label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bugleweed by Herbs Etc.

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0 Not Present Dosage formLiquid Amounts shown are per serving.

Fresh Bugleweed

Interacts with
16 drugs
0 NP per serving

Bugleweed is a traditional herb most often used for mild overactive thyroid symptoms and the rapid heartbeat that can come with it, but high-quality h...

Fresh Bugleweed monograph & interactions

Other (inactive) ingredients: 40% Grain Alcohol, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bugleweed by Herbs Etc. Drug Interactions

Want to check YOUR meds against Bugleweed?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Moderate

Ingredients driving the most interactions

fresh Bugleweed 16

Individual Drug Interactions

The ingredients in Bugleweed interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Bugleweed interact with drugs. Each result below shows which ingredient is responsible. fresh Bugleweed

Each ingredient & the kinds of drugs it affects

For each ingredient in Bugleweed with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

fresh Bugleweed1 drug type · 16 drugs

Thyroid Hormone

Theoretically, bugleweed may alter thyroid function.
Concomitant use of bugleweed may reduce the effects of thyroid hormones by blocking peripheral conversion of thyroxine (T4) to triiodothyronine (T3).

Likelihood Probable Evidence D
fresh Bugleweed full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bugleweed, from the product label.

Herbs Etc.

Name
Herbs, Etc.
Street Address
1340 Rufina Circle
City
Santa Fe
State
NM
ZipCode
87507
Web Address
www.herbsetc.com
Pharmacist Counseling Corner

Bugleweed by Herbs Etc.: Common Questions

Does Bugleweed by Herbs Etc. interact with any medications?
Yes. Based on its ingredients, Bugleweed has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bugleweed contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take bugleweed if I'm on levothyroxine?
Not without talking to your doctor or pharmacist first. Bugleweed may reduce how well your thyroid medication works. This one needs professional guidance — don't start it on your own.
Is bugleweed safe during pregnancy?
No. The safety data advises against using bugleweed in pregnancy. If you're pregnant or planning to be, skip this one.
Can I use bugleweed while breastfeeding?
No. Bugleweed may reduce prolactin and milk production, which is why it shouldn't be used while nursing.
Does bugleweed actually work for hyperthyroidism?
We don't have strong evidence on file either way. The effectiveness rating is insufficient reliable evidence, so the research isn't clear enough for us to say it works.
What's in this liquid besides the herb?
The liquid contains 40% grain alcohol and purified water as inactive ingredients. If you need to avoid alcohol, this form may not be right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bugleweed is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bugleweed label
Go deeper

The Full Monographs Behind Bugleweed’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bugleweed

Interacts with 16 drugs

Bugleweed is a traditional herb most often used for mild overactive thyroid symptoms and the rapid heartbeat that can come with it, but high-quality human evidence is very limited. Because i...

Read the full Bugleweed monograph →
Sources

Sources & How We Checked

Bugleweed's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bugleweed 4 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Bugleweed monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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