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Dietary supplement

Burdock Root 425 mg Ingredients & Drug Interactions

by Pure Naturals Herbs

Burdock Root 425 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Burdock Root 425 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Burdock Root 425 mg is a dietary supplement by Pure Naturals Herbs with 1 active ingredient. Its ingredients are commonly taken for skin conditions like acne and eczema, digestive support, diuretic ('detox') and blood purifier.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Burdock. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Burdock Root 425 mg by Pure Naturals Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Burdock Root 425 mg by Pure Naturals Herbs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Burdock Root 425 mg by Pure Naturals Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This capsule contains one active ingredient: burdock root at 425 mg per dose. Burdock is a plant root that's been used in traditional medicine and eaten as a food for generations.

The capsule itself is made with gelatin and magnesium stearate, which are inactive ingredients that help form and stabilize the product.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Burdock product and its label doesn't state a use — see Burdock's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for burdock root's effectiveness isn't established in the data we hold. Studies haven't produced reliable evidence to rate it for acne, aging skin, breast cancer, common cold, or eczema.

That doesn't mean it doesn't work — it means we don't have solid trial data to confirm whether it does.

The evidence, ingredient by ingredient Burdock

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When eaten as food or used short-term, burdock is generally well tolerated in healthy adults, though human safety data are limited. The main side effects reported are rare allergic reactions, including contact dermatitis and anaphylaxis.

One case of liver inflammation was reported with a multi-ingredient herbal tea containing burdock, though it's unclear whether burdock alone caused it. Contact dermatitis has occurred with prolonged use of burdock root oil or plasters, sometimes days after application.

Don't use medicinal amounts during pregnancy — the safety data aren't there and burdock may affect the uterus. The same caution applies to breastfeeding: there isn't enough safety information to recommend it.

Side effects, ingredient by ingredient Burdock

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Burdock.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood thinners or antiplatelet drugs — like warfarin, aspirin, clopidogrel, dabigatran, or similar medications — double-check with us before starting this product. The interaction is theoretical but documented at a Moderate severity level.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Burdock root is a traditional herbal supplement with limited modern evidence for the conditions it's marketed for, but it's generally well tolerated when used as a food or short-term. If you take blood thinners or antiplatelet drugs, this one needs a conversation with us first.

Pregnant or breastfeeding? Skip it until you've talked to your pharmacist or doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Burdock Root 425 mg, straight from the product label.

Brand Pure Naturals Herbs
Barcode (UPC) 816511022802
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 323840
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Burdock Root 425 mg by Pure Naturals Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
120
UPC/BARCODE
816511022802
IngredientAmount% DV
Burdock425 mg--

Other ingredients: Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, adults take one (1) to two (2) capsules daily, preferably with a meal or as directed by a health care professional. (Capsules may be opened and prepared as tea.)

Precautions

Caution: For adults only.

If you are pregnant, nursing, taking medication(s) or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Visit us online @ purenaturals.co

Herbal remedy

Email: [email protected]

Formulation

Supports blood detoxification Promotes inflammatory response Support overall health & well-being

Contains no: Preservatives, artificial colors, flavors or sweeteners, sugar, milk, lactose, gluten, wheat, yeast, fish or sodium.

An FDA regulated facility

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made in USA Sourced from a GMP Certified Facility Good Manufacturing Practice Quality Assured

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Burdock Root 425 mg by Pure Naturals Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Burdock Root 425 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Burdock Root 425 mg by Pure Naturals Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Burdock

Interacts with
122 drugs
425 mg per serving

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and mo...

Burdock monograph & interactions

Other (inactive) ingredients: Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Burdock Root 425 mg by Pure Naturals Herbs Drug Interactions

Want to check YOUR meds against Burdock Root 425 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Burdock 122

Individual Drug Interactions

The ingredients in Burdock Root 425 mg interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Burdock Root 425 mg interact with drugs. Each result below shows which ingredient is responsible. Burdock

Each ingredient & the kinds of drugs it affects

For each ingredient in Burdock Root 425 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Burdock1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Burdock full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Burdock Root 425 mg, from the product label.

Pure Naturals Herbs

See all Pure Naturals Herbs products
Name
Pure Naturals Herbs
City
Jersey City
State
NJ
Web Address
purenaturals.co
Pharmacist Counseling Corner

Burdock Root 425 mg by Pure Naturals Herbs: Common Questions

Does Burdock Root 425 mg by Pure Naturals Herbs interact with any medications?
Yes. Based on its ingredients, Burdock Root 425 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Burdock Root 425 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data aren't there, and burdock in medicinal amounts may affect your uterus during pregnancy. Avoid it while breastfeeding too — there's not enough information to know it's safe. Talk to your doctor or pharmacist for personalized advice.
Does burdock root actually work for acne or eczema?
We don't have reliable evidence in the data we hold to say it does. That doesn't mean it can't help — just that studies haven't confirmed it yet.
What are the side effects?
Most people tolerate it well, especially when eaten as food. Rare serious side effects are allergic reactions, including contact dermatitis and anaphylaxis. Contact dermatitis has been reported with prolonged use of burdock root oil or plasters, sometimes days after you apply it.
Is this safe to take long-term?
Burdock has a long history of use with few noted side effects, but human safety data for long-term medicinal use are limited. If you're thinking of using it regularly, check with your pharmacist first.
What exactly is burdock?
It's the root of a plant that's been eaten as food and used in traditional medicine for generations. Each capsule here contains 425 mg of burdock root.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Burdock Root 425 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Burdock Root 425 mg label
Go deeper

The Full Monographs Behind Burdock Root 425 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Burdock

Interacts with 122 drugs

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...

Read the full Burdock monograph →
Sources

Sources & How We Checked

Burdock Root 425 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Burdock 11 references
  1. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  2. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
  3. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
  5. Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. DOI
  6. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254. PubMed
  7. Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
  8. Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157. DOI
  9. <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p> DOI
  10. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
  11. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed

See these in context on the Burdock monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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