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Dietary supplement

California Poppy Extract Ingredients & Drug Interactions

by Genesis Today

California Poppy Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking California Poppy Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

California Poppy Extract is a dietary supplement by Genesis Today with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, trouble sleeping (insomnia), mild aches and pains.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are California Poppy (Eschscholzia californica cham.) (aerial part) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against California Poppy Extract by Genesis Today

Ask about any prescription or over-the-counter medication and we check it for interactions with California Poppy Extract by Genesis Today — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of California Poppy Extract by Genesis Today

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: California poppy extract (from the aerial parts of the plant). The capsule itself is made from vegetable material.

California poppy has a long history of traditional use for relaxation and sleep, though the scientific evidence supporting these uses in people remains limited.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see California Poppy's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports rest and peaceful relaxation.
  • We looked for evidence on: Anxiety, Insomnia, nervousness, sleeplessness.
  • The closest evidence on file: California Poppy is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: California Poppy is rated "Insufficient Reliable Evidence To Rate" for Insomnia.

The evidence we hold doesn't yet establish that California poppy works reliably for anxiety, insomnia, or bedwetting (nocturnal enuresis). Each of these uses is rated as having insufficient reliable evidence to rate.

That doesn't mean it doesn't work—it means larger, well-designed human studies are needed to know either way.

The evidence, ingredient by ingredient California Poppy

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

California poppy is generally considered mild for short-term use, but human safety data are limited. When used in combination products containing hawthorn and magnesium, some people have reported muscular stiffness, morning fatigue, and nausea—though it's unclear whether these came from California poppy itself or the other ingredients or their combination.

The safety data available aren't robust enough to recommend this product during pregnancy or while breastfeeding, so those are best avoided unless you've discussed it with your doctor or pharmacist.

Side effects, ingredient by ingredient California Poppy

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — California Poppy.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking California Poppy Extract, check with your doctor or pharmacist if you take any CNS depressants—sedatives, sleep medications, anti-anxiety drugs, or other medicines meant to calm the nervous system. The combination may increase sedative effects.

No other medication types are documented as interacting with this product's ingredient.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

California Poppy Extract might appeal to anyone interested in a traditional herbal approach to relaxation or sleep, but the scientific backing for its effectiveness is still thin. If you take sedatives, sleep aids, or anti-anxiety medications, check with your doctor or pharmacist before starting it—the combination could strengthen drowsiness.

And if you're pregnant, breastfeeding, or dealing with a serious sleep or anxiety condition, talk it over with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about California Poppy Extract, straight from the product label.

Brand Genesis Today
Barcode (UPC) 812711012759
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD May 24, 2017
DSLD ID 73700
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for California Poppy Extract by Genesis Today, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
812711012759
IngredientAmount% DV
California Poppy (Eschscholzia californica cham.) (aerial part) extract533 mg--

Other ingredients: Vegetable capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Picture yourself relaxing in a field of brilliant yellow poppy flowers. Genesis Today's California Poppy Extract is derived from the beautiful flower and is thought to support healthy rest and peaceful relaxation. California Poppy Extract offers support for rest and relaxation in a gentle, non-habit forming supplement.

Austin based

Supports rest & relaxation Supports peaceful relaxation

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

533mg California Poppy per serving

Formulation

Vegetarian

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one (1) capsule three times per day with a full glass of water or as directed by your healthcare provider.

Precautions

Caution: Do not use if seal around cap is broken.

Keep out of reach of children.

Do not take if you are pregnant or nursing.

Storage

Store in a cool, dry place.

General

RDL 18-095 LSGT131-2

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

California Poppy Extract by Genesis Today label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

California Poppy Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in California Poppy Extract by Genesis Today

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

California Poppy (Eschscholzia californica cham.) (aerial part) extract

Interacts with
248 drugs
533 mg per serving Form: Alkaloids

California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs. Human research is...

California Poppy (Eschscholzia californica cham.) (aerial part) extract monograph & interactions

Other (inactive) ingredients: Vegetable capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

California Poppy Extract by Genesis Today Drug Interactions

Want to check YOUR meds against California Poppy Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

California Poppy (Eschscholzia californica cham.) (aerial part) extract 248

Individual Drug Interactions

The ingredients in California Poppy Extract interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in California Poppy Extract interact with drugs. Each result below shows which ingredient is responsible. California Poppy (Eschscholzia californica cham.) (aerial part) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in California Poppy Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

California Poppy (Eschscholzia californica cham.) (aerial part) extract1 drug type · 248 drugs

Cns Depressants

Theoretically, taking California poppy with drugs with sedative effects may increase the risk of sedative effects.
Laboratory research shows that California poppy has sedative effects.

Likelihood Possible Evidence D
California Poppy (Eschscholzia californica cham.) (aerial part) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for California Poppy Extract, from the product label.

Genesis Today

See all Genesis Today products
Name
Genesis Today, Inc.
City
Austin
State
TX
ZipCode
78744
Phone Number
(800) 916-6642
Web Address
GenesisToday.com
Pharmacist Counseling Corner

California Poppy Extract by Genesis Today: Common Questions

Does California Poppy Extract by Genesis Today interact with any medications?
Yes. Based on its ingredients, California Poppy Extract has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
California Poppy Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will California poppy help me sleep?
We don't have enough reliable evidence yet to say whether it works for insomnia. It has a traditional reputation for sleep support and lab studies show it has sedative properties, but human trials haven't confirmed real-world effectiveness.
Is it safe to take long-term?
Human safety data are limited. Short-term use is considered mild, but we don't have strong evidence about what happens with extended use, so talk with your pharmacist or doctor about duration if you're considering this regularly.
Can I take it while pregnant or breastfeeding?
The safety data aren't robust enough to recommend it during pregnancy or while breastfeeding. If you're pregnant or nursing and interested in this product, speak with your doctor or pharmacist to weigh your options.
What are the side effects?
There's limited information about side effects from California poppy alone. In combination products with hawthorn and magnesium, some people reported muscular stiffness, morning fatigue, and nausea, but it's not clear whether those came from California poppy or the other ingredients.
Will it make me too drowsy during the day?
The ingredient has sedative effects, so daytime drowsiness is possible—especially if you're also taking other sedating medications. If you're considering this product and are concerned about daytime alertness, talk it over with your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

California Poppy Extract label
Go deeper

The Full Monographs Behind California Poppy Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

California Poppy

Interacts with 248 drugs

California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs. Human research is very limited, so its true benefits are...

Read the full California Poppy monograph →
Sources

Sources & How We Checked

California Poppy Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

California Poppy 3 references
  1. Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate
  2. Paul LD, Springer D, Staack RF, et al. Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine. Eur J Pharmacol 2004;485:69-79. PubMed
  3. Paul LD, Maurer HH. Studies on the metabolism and toxicological detection of the Eschscholtzia californica alkaloids californine and protopine in urine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2003;789:43-5

See these in context on the California Poppy monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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