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Dietary supplement

California Poppy Seed Ingredients & Drug Interactions

by Bio Nutrition

California Poppy Seed label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking California Poppy Seed against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

California Poppy Seed is a dietary supplement by Bio Nutrition with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, trouble sleeping (insomnia), mild aches and pains.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are California Poppy. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against California Poppy Seed by Bio Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with California Poppy Seed by Bio Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of California Poppy Seed by Bio Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: California poppy. It's a botanical traditionally used for relaxation and sleep support.

The inactive ingredients are vegetable stearate, vegetable cellulose, and silica — common capsule materials and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see California Poppy's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: promote relaxation, sleep and pain relief.
  • We looked for evidence on: Anxiety, Insomnia, stress, nervous tension.
  • The closest evidence on file: California Poppy is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: California Poppy is rated "Insufficient Reliable Evidence To Rate" for Insomnia.

The evidence for California poppy isn't established in our data. We hold ratings of insufficient reliable evidence for anxiety, insomnia, and nocturnal enuresis (bedwetting).

That means the research so far hasn't been strong enough to confirm whether it actually works for these uses — not that it doesn't work, just that we can't say from the studies available.

The evidence, ingredient by ingredient California Poppy

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

California poppy is generally considered mild for short-term use, though human safety data are limited. The side-effect information we hold is sparse — most reports come from combination products with other herbs, and it's unclear whether California poppy itself or the combination caused the effects reported.

Safety data during pregnancy and breastfeeding are not adequate, so the data advise against it in both situations. Talk with your doctor or pharmacist before use if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient California Poppy

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — California Poppy.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start California Poppy Seed, double-check all CNS depressants (sedative drugs) — sleep aids, anti-anxiety medications, certain pain relievers, and similar drugs — with your own doctor or pharmacist. Taking this product alongside them may increase sedation beyond what either would cause alone.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

California poppy might appeal to you if you're looking for a mild herbal relaxation aid, but keep in mind the evidence for its effectiveness isn't solid yet. If you take any sedative medication — sleep aids, anxiety drugs, or certain pain relievers — this product could boost drowsiness, so check with your doctor or pharmacist first.

Pregnant or breastfeeding? Skip it unless your healthcare provider says otherwise.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about California Poppy Seed, straight from the product label.

Brand Bio Nutrition
Barcode (UPC) 854936003204
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 200561
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for California Poppy Seed by Bio Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
854936003204
IngredientAmount% DV
California Poppy500 mg--

Other ingredients: Vegetable Stearate, Vegetable Cellulose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one (1) capsule at bedtime or as needed.

Formula

Description: For centuries the miracle Poppy plant has been used as a natural remedy to promote relaxation, sleep and pain relief. Bio Nutrition uses only the highest quality California Poppy Seed Extract (Narcotic-free).

Formulation

Bio Nutrition uses only the highest quality California Poppy Seed Extract (Narcotic-free).

Made in an easy to swallow vegetarian capsule.

Vegetarian

Free of gluten, yeast, corn, sugar, salt, wheat, soy, artificial ingredients and preservatives.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Recycle Made in USA

Each serving supplies:

Seals/Symbols

Vegetarian

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

California Poppy Seed by Bio Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

California Poppy Seed label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in California Poppy Seed by Bio Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

California Poppy

Interacts with
248 drugs
500 mg per serving

California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs. Human research is...

California Poppy monograph & interactions

Other (inactive) ingredients: Vegetable Stearate, Vegetable Cellulose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

California Poppy Seed by Bio Nutrition Drug Interactions

Want to check YOUR meds against California Poppy Seed?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

California Poppy 248

Individual Drug Interactions

The ingredients in California Poppy Seed interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in California Poppy Seed interact with drugs. Each result below shows which ingredient is responsible. California Poppy

Each ingredient & the kinds of drugs it affects

For each ingredient in California Poppy Seed with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

California Poppy1 drug type · 248 drugs

Cns Depressants

Theoretically, taking California poppy with drugs with sedative effects may increase the risk of sedative effects.
Laboratory research shows that California poppy has sedative effects.

Likelihood Possible Evidence D
California Poppy full monograph & interactions
The maker

Brand information

Manufacturer and brand details for California Poppy Seed, from the product label.

Bio Nutrition

See all Bio Nutrition products
Name
Bio Nutrition, Inc.
City
Island Park
State
NY
ZipCode
11558
Phone Number
516-432-1590
Web Address
www.bionutritioninc.com
Pharmacist Counseling Corner

California Poppy Seed by Bio Nutrition: Common Questions

Does California Poppy Seed by Bio Nutrition interact with any medications?
Yes. Based on its ingredients, California Poppy Seed has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
California Poppy Seed contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does California poppy actually help with sleep or anxiety?
The evidence isn't established yet. We have ratings of insufficient reliable evidence for both insomnia and anxiety — meaning the research so far hasn't been strong enough to confirm it works for either one.
Can I take this with my sleep medication?
That's a question for your doctor or pharmacist. California poppy has sedative effects, so taking it with sleep aids or other sedative drugs might increase drowsiness more than either alone would. Your healthcare provider can tell you whether it's safe for your situation.
What side effects should I watch for?
Detailed side-effect data are limited. Reports from combination products containing California poppy, hawthorn, and magnesium mention muscular stiffness, morning fatigue, and nausea — though it's unclear whether California poppy caused these or the other ingredients did.
Is it safe if I'm pregnant or breastfeeding?
No — the safety data advise against it in both situations. There isn't enough research to know it's safe, so talk with your doctor or pharmacist before considering it if you're pregnant, planning pregnancy, or nursing.
What's actually in this product?
One capsule contains California poppy, the active ingredient, plus inactive materials — vegetable stearate, vegetable cellulose, and silica — that make up the capsule and help keep it stable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if California Poppy Seed is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

California Poppy Seed label
Go deeper

The Full Monographs Behind California Poppy Seed’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

California Poppy

Interacts with 248 drugs

California poppy is a traditional herbal remedy used mainly for anxiety and sleep problems, often combined with other calming herbs. Human research is very limited, so its true benefits are...

Read the full California Poppy monograph →
Sources

Sources & How We Checked

California Poppy Seed's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

California Poppy 3 references
  1. Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate
  2. Paul LD, Springer D, Staack RF, et al. Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine. Eur J Pharmacol 2004;485:69-79. PubMed
  3. Paul LD, Maurer HH. Studies on the metabolism and toxicological detection of the Eschscholtzia californica alkaloids californine and protopine in urine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2003;789:43-5

See these in context on the California Poppy monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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