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Dietary supplement

White Mulberry Leaf Tea Ingredients & Drug Interactions

by Bio Nutrition

White Mulberry Leaf Tea label
See full label image
Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking White Mulberry Leaf Tea against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

White Mulberry Leaf Tea is a dietary supplement by Bio Nutrition with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, high cholesterol, weight management.Based on those ingredients, 87 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are White Mulberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against White Mulberry Leaf Tea by Bio Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with White Mulberry Leaf Tea by Bio Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of White Mulberry Leaf Tea by Bio Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This tea contains one active ingredient: white mulberry leaf. That's it — no other active ingredients, and no inactive fillers or additives are listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see White Mulberry's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support healthy blood sugar level.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (prediabetes), Hyperlipidemia, Hypertension, Obesity, metabolic syndrome — and 1 related terms.
  • The closest evidence on file: White Mulberry is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: White Mulberry is rated "Insufficient Reliable Evidence To Rate" for Hyperlipidemia, Hypertension, Obesity, Impaired glucose tolerance (prediabetes).

The evidence for white mulberry leaf is limited. The data we hold shows insufficient reliable evidence to rate it for androgenic alopecia (hair loss), osteoporosis, common cold, diabetes, or high cholesterol (hyperlipidemia).

In other words, we don't have solid clinical proof that it works for these uses yet.

The evidence, ingredient by ingredient White Mulberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

White mulberry leaf is generally well tolerated when taken by mouth. In a clinical study, people taking 4.6 grams three times daily for up to 12 weeks experienced bloating and gas in about half of the participants, loose stools in a quarter, and constipation in a fifth — but these side effects tended to fade as the study went on, so they may be temporary.

As a food, mulberry leaf is considered likely safe. However, concentrated supplements are less well studied and can lower blood sugar.

The safety data during pregnancy and breastfeeding isn't strong enough to recommend medicinal amounts — talk with your doctor or pharmacist for personalized advice on whether it's right for you.

Side effects, ingredient by ingredient White Mulberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — White Mulberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 87 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this tea, check whether you take any diabetes medications (antidiabetes drugs) — white mulberry leaf can increase the risk of low blood sugar with these. You should also double-check if any of your medications are OCT2 substrates, since white mulberry leaf may slow their clearance.

Use the medication checker below to look up your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're thinking about this tea for general wellness, it's likely well tolerated and may cause temporary digestive upset in some people. But if you take diabetes medication or any drug that uses OCT2 transporters to clear from your kidneys, you need to check your specific medications before starting.

Talk to your pharmacist — they can tell you if this product will interfere with what you're taking.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about White Mulberry Leaf Tea, straight from the product label.

Brand Bio Nutrition
Barcode (UPC) 854936003549
Net contents 1.61 Oz(s); 45 Gram(s); 30 Tea Bag(s)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 200798
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for White Mulberry Leaf Tea by Bio Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Not Present
Maximum serving Sizes:
2 Not Present
UPC/BARCODE
854936003549
IngredientAmount% DV
White Mulberry0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Steep one tea bag for several minutes once or twice daily, may be sweetened to taste and can be enjoyed hot or cold.

General Statements

Recycle Made in USA

Blood Sugar Controller Supports an Active Lifestyle

Formulation

Vegetarian

Free of gluten, yeast, corn, dairy, sugar, salt, wheat, soy and preservatives

Seals/Symbols

Vegetarian

Formula

Bio Nutrition selects the finest White Mulberry leaves for the production of this healthful tea. White Mulberry Leaf has been traditionally used to support healthy blood sugar level.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

White Mulberry Leaf Tea by Bio Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

White Mulberry Leaf Tea label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in White Mulberry Leaf Tea by Bio Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Not Present Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

White Mulberry

Interacts with
87 drugs
0 NP per serving

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is gen...

White Mulberry monograph & interactions
Interaction report

White Mulberry Leaf Tea by Bio Nutrition Drug Interactions

Want to check YOUR meds against White Mulberry Leaf Tea?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
87Drugs
87 Moderate

Ingredients driving the most interactions

White Mulberry 87

Individual Drug Interactions

The ingredients in White Mulberry Leaf Tea interact with 87 drugs. Click any drug to see the details.

1 of the 1 ingredient in White Mulberry Leaf Tea interact with drugs. Each result below shows which ingredient is responsible. White Mulberry

Each ingredient & the kinds of drugs it affects

For each ingredient in White Mulberry Leaf Tea with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

White Mulberry2 drug types · 87 drugs

Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that white mulberry leaf can lower blood glucose levels. Advise patients to monitor glucose levels closely.

Likelihood Possible Evidence D
Organic Cation Transporter 2 (Oct2) Substrates

Theoretically, white mulberry leaf might slow the elimination and increase the adverse effects of drugs which are OCT2 substrates.
Animal research shows that coadministration of white mulberry leaf extract with metformin, an OCT2 substrate, slows the renal elimination of metformin via inhibition of OCT2 activity. OCT2 is expressed in the kidneys and is responsible for transporting cationic drugs into tubular epithelial cells in order to be excreted in the urine.

Likelihood Possible Evidence D
White Mulberry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for White Mulberry Leaf Tea, from the product label.

Bio Nutrition

See all Bio Nutrition products
Name
Bio Nutrition, Inc.
City
Island Park
State
NY
ZipCode
11558
Phone Number
516-432-1590
Web Address
www.bionutritioninc.com
Pharmacist Counseling Corner

White Mulberry Leaf Tea by Bio Nutrition: Common Questions

Does White Mulberry Leaf Tea by Bio Nutrition interact with any medications?
Yes. Based on its ingredients, White Mulberry Leaf Tea has a known interaction with 87 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
White Mulberry Leaf Tea contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this tea actually help my diabetes or cholesterol?
The evidence isn't established in the data we hold. We have insufficient reliable evidence to rate white mulberry leaf for diabetes or high cholesterol. It *can* lower blood glucose, which is why you need to be careful if you're already on diabetes medication — but we don't have solid proof it's an effective treatment on its own.
What side effects should I expect?
Most people tolerate it well. The most common side effects are temporary digestive ones — bloating, gas, loose stools, or constipation — but they tend to fade over a few weeks. About half of study participants had bloating or gas, a quarter had loose stools, and a fifth had constipation, but these improved as time went on.
Is it safe to drink while pregnant or breastfeeding?
There isn't enough safety data to know either way with medicinal amounts. Talk with your doctor or pharmacist before using this during pregnancy or while breastfeeding — they can give you personalized advice based on your situation.
Can I drink this if I take metformin?
You need to talk to your pharmacist first. Metformin is both a diabetes drug and an OCT2 substrate, so white mulberry leaf creates a double concern: it can lower blood sugar *and* slow how your kidneys clear metformin. Your pharmacist can help you decide whether it's safe for you and how to monitor yourself.
What is white mulberry leaf supposed to do?
We have data showing it can lower blood glucose levels. The research is less clear on whether it's effective for hair loss, bone health, colds, or cholesterol — that's why the evidence is rated insufficient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if White Mulberry Leaf Tea is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

White Mulberry Leaf Tea label
Go deeper

The Full Monographs Behind White Mulberry Leaf Tea’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

White Mulberry

Interacts with 87 drugs

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is generally well tolerated as a food and tea,...

Read the full White Mulberry monograph →
Sources

Sources & How We Checked

White Mulberry Leaf Tea's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

White Mulberry 6 references
  1. Andallu B, Suryakantham V, Lakshmi Srikanthi B, Reddy GK. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 2001;314:47-53. PubMed
  2. Mudra M, Ercan-Fang N, Zhong L, et al. Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic and control subjects. Diabetes Care 2007;30:1272-4. PubMed
  3. Kimura T, Nakagawa K, Kubota H, et al. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 2007;55:5869-74. PubMed
  4. Huh HW, Na YG, Bang KH, et al. Extended intake of mulberry leaf extract delayed metformin elimination via inhibiting the organic cation transporter 2. Pharmaceutics. 2020;12(1):49. PubMed
  5. Thaipitakwong T, Supasyndh O, Rasmi Y, Aramwit P. A randomized controlled study of dose-finding, efficacy, and safety of mulberry leaves on glycemic profiles in obese persons with borderline diabetes. Complement Ther Med. 2020;49:102292. PubMed
  6. Thondre PS, Lightowler H, Ahlstrom L, Gallagher A. Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study. Nutr Metab (Lond) 2021;18(1):41. PubMed

See these in context on the White Mulberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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