Cang Zhu Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Cang Zhu against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cang Zhu is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for digestive upset and poor appetite, bloating and fluid retention, general fatigue or 'weakness'.Based on those ingredients, 801 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Atractylis lancea Root Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Cang Zhu by Herbal Terra
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AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Cang Zhu by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This liquid contains one active ingredient: atractylodes root extract (in dry form). Atractylodes is a plant used traditionally in herbal medicine, though what it actually does in the body isn't well established by research.
The product also contains alcohol, water, and glycerin as inactive ingredients that help deliver and preserve the extract.
Does it work?
Couldn't assess
The evidence for what atractylodes does isn't established in our data. It's been studied traditionally for anorexia nervosa, cancer cachexia (wasting), lung cancer, common cold, and diarrhea, but in each case the reliable evidence is insufficient to rate whether it works.
If you're considering this for a specific condition, talk with your pharmacist or doctor about whether there's solid evidence behind it.
How safe is it?
Well-documented data
Human safety data for atractylodes are limited, so use this product cautiously and under guidance from a healthcare provider. The most common side effects reported orally are allergic reaction, dry mouth, and nausea.
The safety data advises against use during pregnancy, and safety while breastfeeding is unknown, so it's best avoided if you're pregnant or nursing. A thorough safety evaluation hasn't been completed, so unexpected effects are possible.
Meds to double-check
Moderate interaction found
Check your medications against this product if you take blood thinners or antiplatelet drugs (like warfarin, clopidogrel, or aspirin), aromatase inhibitors for cancer, or any medication your liver breaks down — especially if it's a narrow-window drug where even small changes matter.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Cang Zhu is a traditional herbal product with limited human safety data and theoretical interactions with blood thinners and several other medication types — none proven in people yet, but worth checking. If you take any prescription medications, especially blood thinners or cancer drugs, run them through our checker before starting.
Talk with your pharmacist about whether the evidence supports what you're hoping it will do.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cang Zhu, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7386004903954 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2024 |
| DSLD ID | 324882 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cang Zhu by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Atractylis lancea Root Extract, Dry | 983 mg | -- |
Other ingredients: Alcohol, Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.
Precautions
We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!
Do not use if you are allergic to any ingredients.
Storage
Store in a cool, dry, dark place.
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Sugar free
Expertly extracted 100% natural Premium product
Organic alcohol
No artificial ingredients, color additives, fillers or binders.
Natural Gluten free
Formula
Atractylis lancea
Organic alcohol
FDA Statement of Identity
Herbal Supplement
General Statements
Organic raw material.
Seals/Symbols
Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cang Zhu by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cang Zhu by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Atractylis lancea Root Extract, Dry
Interacts with801 drugs
Atractylodes is a root used for centuries in traditional Chinese, Japanese, and Thai medicine, mostly for digestive complaints and fatigue, often as p...
Atractylis lancea Root Extract, Dry monograph & interactionsOther (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Cang Zhu by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Cang Zhu by Herbal Terra contains atractylodes, a botanical that interacts with several medication types.
The most serious concern is with blood thinners and antiplatelet drugs (like warfarin or aspirin) — atractylodes may theoretically increase your bleeding risk, though this hasn't been proven in humans yet, only in the lab.
Read the full breakdown — every affected drug type, severity by severity
It also has moderate theoretical interactions with aromatase inhibitors (used for hormone-sensitive cancers) and hexobarbital (a sedative rarely used today). Additionally, atractylodes may affect how your body processes certain medications broken down by CYP1A2 and CYP3A4 enzymes — potentially lowering levels of some drugs or raising levels of others.
Again, these are animal findings not yet shown in people.
Altogether, these interactions span 791 individual medications. Before you start this product, run your exact medications through the checker below — especially if you take blood thinners, cancer drugs, or anything metabolized by your liver.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Cang Zhu?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Cang Zhu interact with 801 drugs. Click any drug to see the details.
1 of the 1 ingredient in Cang Zhu interact with drugs. Each result below shows which ingredient is responsible. Atractylis lancea Root Extract, Dry
AbciximabReoPro
How Abciximab interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylis Lancea Root Extract, Dry + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Anagrelide interactionAnastrozoleArimidex
How Anastrozole interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAromatase Inhibitors Moderate
Interaction Summary
Theoretically, atractylodes may have an additive effect when used with other aromatase inhibitors.
Read the full Atractylis Lancea Root Extract, Dry + Anastrozole interactionAnisindioneMiradon
How Anisindione interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylis Lancea Root Extract, Dry + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Cang Zhu — through 1 ingredient. Tap an ingredient for the detail:
Atractylis Lancea Root Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylis Lancea Root Extract, Dry + Aspirin, Caffeine, Orphenadrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Cang Zhu with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Atractylis lancea Root Extract, Dry
Anticoagulant/Antiplatelet Drugs
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Laboratory research suggests that atractylenolides II and III, constituents of atractylodes, reduce platelet activation. So far, this has not been shown in humans.
Aromatase Inhibitors
Theoretically, atractylodes may have an additive effect when used with other aromatase inhibitors.
Laboratory research suggests that atractylodes and its constituents exhibit aromatase inhibitor effects.
Hexobarbital
Theoretically, taking atractylodes may prolong the therapeutic and adverse effects of hexobarbital.
In animals, atractylodes has been shown to prolong the effects of hexobarbital. These effects have not been shown in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
In animals, atractylodes administered at high doses has been shown to induce CYP1A2 activity. This effect has not been shown in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
In animals, atractylodes administered at high doses has been shown to inhibit CYP3A1 activity, which is a homolog to the human CYP3A4 enzyme. This effect has not been shown in humans.
Brand information
Manufacturer and brand details for Cang Zhu, from the product label.
Herbal Terra
See all Herbal Terra products- Name
- Herbal Terra LLC
- Phone Number
- +18083857868
- Web Address
- herbalterra.com
Cang Zhu by Herbal Terra: Common Questions
Does Cang Zhu by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is Cang Zhu safe to take if I'm pregnant or breastfeeding?
What are the most common side effects?
Does atractylodes actually work for anything?
What is atractylodes and why is it in this product?
Will this interact with my blood thinner?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cang Zhu is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cang Zhu’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cang Zhu's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Atractylodes 6 references
- Liu Y, Jia Z, Dong L, et al. A randomized pilot study of atractylenolide I on gastric cancer cachexia patients. Evid Based Complement Alternat Med 2008;5:337-44. PubMed
- Chen Y, Yang W, Guo L, Wu X, Zhang T, Liu J, Zhang J. Atractylodes lactone compounds inhibit platelet activation. Platelets. 2017 Mar;28(2):194-202. PubMed
- Jiang H, Shi J, Li Y. Screening for compounds with aromatase inhibiting activities from Atractylodes macrocephala Koidz. Molecules. 2011 Apr 14;16(4):3146-51. PubMed
- Koonrungsesomboon N, Na-Bangchang K, Karbwang J. Therapeutic potential and pharmacological activities of Atractylodes lancea (Thunb.) DC. Asian Pac J Trop Med. 2014 Jun;7(6):421-8. PubMed
- Li L, Tang LY, Man GC, Yeung BH, Lau CB, Leung PC, Wang CC. Potential reproductive toxicity of Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage. Hum Reprod. 2011 Dec;26(12):3280-8. PubMed
- Muhamad N, Plengsuriyakarn T, Na-Bangchang K. Atractylodes lancea for cholangiocarcinoma: Modulatory effects on CYP1A2 and CYP3A1 and pharmacokinetics in rats and biodistribution in mice. PLoS One 2022;17(11):e0277614. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC