Catnip Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Catnip against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Catnip is a dietary supplement by Nature's Sunshine with 1 active ingredient. Its ingredients are commonly taken for sleep and insomnia, anxiety and stress, digestive upset.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Catnip. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Catnip by Nature's Sunshine
Ask about any prescription or over-the-counter medication and we check it for interactions with Catnip by Nature's Sunshine — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Catnip by Nature's Sunshine
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: catnip. The capsule itself is an inactive ingredient used to deliver the catnip powder.
Does it work?
Not established
The evidence for catnip's effectiveness isn't established in the data we hold. We have insufficient reliable evidence to rate it for amenorrhea, anxiety, tension headaches, upper respiratory tract infections, indigestion, or gas.
If you're considering catnip for any of these, talk with your doctor about whether the evidence supports it for your situation.
How safe is it?
Some data gaps
Catnip is generally well tolerated when taken by mouth in typical amounts, though human safety data are limited. The most common side effects reported are headache, malaise, and vomiting.
Taking too much may also cause stomachache. Catnip is not recommended during pregnancy, as it may stimulate the uterus and its safety in pregnancy is not established.
There isn't enough safety information available for other situations either, so discuss this with your doctor or pharmacist if you're pregnant, breastfeeding, or have specific health concerns.
Meds to double-check
Moderate interaction found
Before taking catnip, check with your doctor or pharmacist if you take CNS depressants (drugs that cause drowsiness or sedation, including sleep aids and anti-anxiety medications) or lithium. Catnip may amplify drowsiness with the first group and could alter lithium levels with the second.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.
Catnip may appeal to you if you're exploring herbal options for anxiety or sleep, but the evidence supporting those uses isn't solid yet. If you take CNS depressants (like sleeping pills or anti-anxiety drugs) or lithium, check with your doctor or pharmacist first—the interactions are real and could affect how those medications work.
A conversation with your own healthcare provider will help you decide if this is the right choice for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Catnip, straight from the product label.
| Brand | Nature's Sunshine |
|---|---|
| Barcode (UPC) | 099904001800 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 278039 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Catnip by Nature's Sunshine, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Bottle made from 100% post consumer recycled material. We are committed to you and our planet. Scan to learn more. We source the world's purest ingredients, no matter where they are grown, to ensure the active nutrients are delivered just as nature intended.
New look! Same great product
Seals/Symbols
Ko Pareve (Kosher)
Formula
Ko Pareve (Kosher)
Precautions
Do not use if inner seal is missing or damaged.
Formulation
Calming support Traditional nervous system support
Guaranteed pure
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
Natures Sunshine Herbal experts since 1972
Suggested/Recommended/Usage/Directions
Recommended Use: Take 2 capsules with a meal three times daily.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Catnip by Nature's Sunshine label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Catnip by Nature's Sunshine
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.
Catnip
Interacts with248 drugs
Catnip is a mint-family herb most often used as a calming tea for sleep, anxiety, and minor digestive upset, but solid human research supporting these...
Catnip monograph & interactionsOther (inactive) ingredients: Capsule. These complete the product’s ingredient list but are not active constituents.
Catnip by Nature's Sunshine Drug Interactions
HelloPharmacist Interaction Report
Catnip by Nature's Sunshine can interact with medications, most notably with drugs that slow down your central nervous system.
When catnip's sedative properties combine with CNS depressants—like sleeping pills, anti-anxiety medications, or pain relievers that cause drowsiness—you may experience additive sedation and side effects. Talk with your doctor or pharmacist before combining them.
Read the full breakdown — every affected drug type, severity by severity
Catnip may also affect lithium levels. Because catnip is thought to have mild diuretic properties, it could theoretically reduce how much lithium your body excretes, raising its concentration in your blood.
If you take lithium for mood disorders, your doctor may need to adjust your dose.
Altogether, these interactions span 248 individual medications. Use the search tool below to check your specific prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Catnip?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Catnip interact with 248 drugs. Click any drug to see the details.
1 of the 1 ingredient in Catnip interact with drugs. Each result below shows which ingredient is responsible. Catnip
AmitriptylineElavil
How Amitriptyline interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Amitriptyline, Perphenazine interactionAmobarbitalAmytal
How Amobarbital interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Amobarbital, Secobarbital interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aprobarbital, Butabarbital, Phenobarbital interactionAripiprazoleAbilify, Abilify Maintena, Abilify Mycite
How Aripiprazole interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aripiprazole interactionAripiprazole LauroxilAristada, Aristada Initio Kit
How Aripiprazole Lauroxil interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aripiprazole Lauroxil interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Hydrocodone interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Aspirin, Pentazocine interactionAtropine, Hyoscyamine, PhenobarbitalHypnaldyne
How Atropine, Hyoscyamine, Phenobarbital interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Atropine, Hyoscyamine, Phenobarbital interactionAtropine, Hyoscyamine, Phenobarbital, ScopolamineBarbidonna No. 2, Belladonna Phenobarbital
How Atropine, Hyoscyamine, Phenobarbital, Scopolamine interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionAtropine, Hyoscyamine, Scopolamine, PhenobarbitalBarbeloid, Donnatal #2, Donphen
How Atropine, Hyoscyamine, Scopolamine, Phenobarbital interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionAtropine, PhenobarbitalAnthrocol
How Atropine, Phenobarbital interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Atropine, Phenobarbital interactionAtropine, MeperidineAtropine, Meperidine
How Atropine, Meperidine interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Atropine, Meperidine interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Atropine, Morphine Sulfate interactionBelladona Extract, PhenobarbitalChardonna-2
How Belladona Extract, Phenobarbital interacts with Catnip — through 1 ingredient. Tap an ingredient for the detail:
CatnipCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Catnip + Belladona Extract, Phenobarbital interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Catnip with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Catnip
Cns Depressants
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Clinical and animal research shows that catnip has sedative properties.
Lithium
Theoretically, catnip might reduce excretion and increase levels of lithium.
Catnip is thought to have diuretic properties which might reduce lithium excretion. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Catnip, from the product label.
Nature's Sunshine
See all Nature's Sunshine products- Name
- Nature's Sunshine Products, Inc.
- City
- Spanish Fork
- State
- UT
- ZipCode
- 84660
- Phone Number
- 1-800-223-8225
- Web Address
- www.naturessunshine.com
Catnip by Nature's Sunshine: Common Questions
Does Catnip by Nature's Sunshine interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will catnip make me drowsy?
Is catnip safe during pregnancy?
Can I take catnip with my sleeping pills?
Does catnip actually work for anxiety or sleep?
What's in each capsule?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Catnip is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Catnip’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Catnip's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Catnip 7 references
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Osterhoudt KC, Lee SK, Callahan JM, Henretig FM. Catnip and the alteration of human consciousness. Vet Hum Toxicol 1997;39:373-5.
- Sherry, C. J. and Hunter, P. S. The effect of an ethanol extract of catnip (Nepeta cataria) on the behavior of the young chick. Experientia 2-15-1979;35(2):237-238. PubMed
- Harney, J. W., Barofsky, I. M., and Leary, J. D. Behavioral and toxicological studies of cyclopentanoid monoterpenes from Nepeta cataria. Lloydia. 1978;41(4):367-374.
- Massoco, C. O., Silva, M. R., Gorniak, S. L., Spinosa, M. S., and Bernardi, M. M. Behavioral effects of acute and long-term administration of catnip (Nepeta cataria) in mice. Vet.Hum.Toxicol 1995;37(6):530-533.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC