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Dietary supplement

Catnip Ingredients & Drug Interactions

by Pure Herbs

Catnip label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Catnip against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Catnip is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for sleep and insomnia, anxiety and stress, digestive upset.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Catnip Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Catnip by Pure Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Catnip by Pure Herbs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Catnip by Pure Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: catnip aerial parts extract (the leaves, stems, and flowering tops). The extract form concentrates the plant's compounds into a liquid for easier dosing.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Catnip's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: relieve temporary muscle spasms and occasional gas.
  • We looked for evidence on: Flatulence, Dyspepsia, muscle tension, cramping.
  • The closest evidence on file: Catnip is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).
  • Also on file: Catnip is rated "Insufficient Reliable Evidence To Rate" for Flatulence.

The evidence for catnip is limited. Our data shows insufficient reliable evidence to rate its effectiveness for amenorrhea, anxiety, tension headaches, upper respiratory tract infections, indigestion (dyspepsia), or bloating (flatulence).

While catnip has a long history of traditional use, the clinical evidence to support it for these conditions isn't yet established in our monograph.

The evidence, ingredient by ingredient Catnip

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Catnip is generally well tolerated when used in amounts typical for tea. However, human safety data are limited, so caution is warranted.

The most common side effects from oral use are headache, malaise (a general sense of discomfort), and vomiting. Taking too much catnip may cause stomach upset and vomiting; in one case, a toddler who ingested a large amount of catnip tea developed stomach pain, irritability, and then lethargy and a hypnotic (sleep-like) state.

Avoid catnip during pregnancy—it may stimulate the uterus and safety has not been established. There is not enough safety information available for other situations, so talk with your pharmacist or doctor before using it if you have any health concerns.

Side effects, ingredient by ingredient Catnip

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Catnip.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take lithium (a mood stabilizer)—catnip may raise its levels. Also double-check any central nervous system depressants, such as sedatives, sleep aids, anxiety medications, or certain pain relievers, as catnip may add to their sedative effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Catnip has a traditional history but limited scientific evidence for most conditions. If you're interested in trying it, steer clear if you take lithium or CNS depressants like sedatives or anxiety medications—those interactions are real.

Talk with your pharmacist or doctor before starting, especially if you're pregnant, breastfeeding, or have other health conditions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Catnip, straight from the product label.

Brand Pure Herbs
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 279302
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Catnip by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
60
IngredientAmount% DV
Catnip Aerial Parts Extract1881 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.

Shake well before use

Formulation

Provides nourishment for the nervous system. Helps to relieve temporary muscle spasms and occasional gas.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.

Discontinue use and consult with your doctor if any adverse reactions occur.

Keep out of reach of children

Brand IP Statement(s)

Pure Herbs, Ltd. Natural Herbal Extracts

FDA Statement of Identity

Dietary Supplement

General Statements

"No expense has been spared to provide the finest nature has to offer."

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Catnip by Pure Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Catnip label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Catnip by Pure Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Catnip Aerial Parts Extract

Interacts with
248 drugs
1881 mg per serving

Catnip is a mint-family herb most often used as a calming tea for sleep, anxiety, and minor digestive upset, but solid human research supporting these...

Catnip Aerial Parts Extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Catnip by Pure Herbs Drug Interactions

Want to check YOUR meds against Catnip?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
248 Moderate

Ingredients driving the most interactions

Catnip Aerial Parts Extract 248

Individual Drug Interactions

The ingredients in Catnip interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Catnip interact with drugs. Each result below shows which ingredient is responsible. Catnip Aerial Parts Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Catnip with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Catnip Aerial Parts Extract2 drug types · 248 drugs

Cns Depressants

Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Clinical and animal research shows that catnip has sedative properties.

Likelihood Possible Evidence D
Lithium

Theoretically, catnip might reduce excretion and increase levels of lithium.
Catnip is thought to have diuretic properties which might reduce lithium excretion. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Catnip Aerial Parts Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Catnip, from the product label.

Pure Herbs

See all Pure Herbs products
Name
Pure Herbs, Ltd.
City
Sterling Heights
State
MI
Phone Number
(800) 860-4372
Web Address
www.pureherbs.com
Pharmacist Counseling Corner

Catnip by Pure Herbs: Common Questions

Does Catnip by Pure Herbs interact with any medications?
Yes. Based on its ingredients, Catnip has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Catnip contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
No, you should avoid catnip during pregnancy. It may stimulate the uterus and safety hasn't been established. Talk with your doctor or pharmacist about alternatives.
What are the side effects?
When used in normal amounts, catnip is generally well tolerated. The most common side effects are headache, malaise, and vomiting. Taking too much can cause stomach upset; a single case report described a toddler who became very drowsy after ingesting a large amount of catnip tea.
Does catnip actually work for anxiety or sleep?
The evidence isn't established enough to say. Our data shows insufficient reliable evidence to rate catnip for anxiety. While it does have sedative properties, we don't have solid clinical proof it helps either condition.
Is this safe for me if I don't take any medications?
Catnip is likely fine for most adults in tea-like amounts, though human safety data are limited. The most common side effects are mild—headache, malaise, and vomiting. If you have any health conditions or concerns, check with your pharmacist first.
What is catnip aerial parts extract?
It's a concentrated liquid made from the leaves, stems, and flowers of the catnip plant. This form allows for easier dosing than the dried herb alone.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Catnip is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Catnip label
Go deeper

The Full Monographs Behind Catnip’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Catnip

Interacts with 248 drugs

Catnip is a mint-family herb most often used as a calming tea for sleep, anxiety, and minor digestive upset, but solid human research supporting these uses is lacking. It is generally consid...

Read the full Catnip monograph →
Sources

Sources & How We Checked

Catnip's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Catnip 7 references
  1. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Osterhoudt KC, Lee SK, Callahan JM, Henretig FM. Catnip and the alteration of human consciousness. Vet Hum Toxicol 1997;39:373-5.
  5. Sherry, C. J. and Hunter, P. S. The effect of an ethanol extract of catnip (Nepeta cataria) on the behavior of the young chick. Experientia 2-15-1979;35(2):237-238. PubMed
  6. Harney, J. W., Barofsky, I. M., and Leary, J. D. Behavioral and toxicological studies of cyclopentanoid monoterpenes from Nepeta cataria. Lloydia. 1978;41(4):367-374.
  7. Massoco, C. O., Silva, M. R., Gorniak, S. L., Spinosa, M. S., and Bernardi, M. M. Behavioral effects of acute and long-term administration of catnip (Nepeta cataria) in mice. Vet.Hum.Toxicol 1995;37(6):530-533.

See these in context on the Catnip monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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