Cheaters Relief Ingredients & Drug Interactions
by BSN
What is this page for?
First and foremost: checking Cheaters Relief against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cheaters Relief is a dietary supplement by BSN with 9 active ingredients. Its ingredients are commonly taken for blood sugar control, high cholesterol, hangover symptoms.Based on those ingredients, 916 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Citrillin HCA, Fenugreek extract, R-ALA. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Cheaters Relief by BSN
Ask about any prescription or over-the-counter medication and we check it for interactions with Cheaters Relief by BSN — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Cheaters Relief by BSN
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Cheaters Relief contains 9 ingredients, six of which are active: Prickly Pear Cactus, Chitosan, Cassia Nomame extract, Citrillin HCA (garcinia), R-ALA (alpha-lipoic acid), and Fenugreek extract. The product also includes proprietary blends called the Cheaters Relief Proprietary Matrix, Fat Relief Blend, and Carb Relief Blend, as well as three inactive ingredients—magnesium stearate, gelatin, and silicon dioxide—used as binders and capsule material.
Three ingredients—Phaseo-Lean and Cinnulin-PF—have no interaction data on file, and effectiveness information for some of the blends isn't detailed.
Does it work?
Moderate evidence
Evidence for the active ingredients varies. Prickly Pear Cactus is possibly effective for diabetes.
Chitosan is possibly effective for obesity, postoperative recovery, and high blood pressure. Alpha-lipoic Acid (R-ALA) is possibly effective for diabetic nerve damage (neuropathy), high cholesterol, and obesity.
Fenugreek extract is possibly effective for sexual dysfunction, sexual arousal, difficult menstrual periods (dysmenorrhea), and diabetes. For Citrillin HCA (garcinia), the evidence we hold shows insufficient reliable evidence for athletic performance, fatty liver disease, and high cholesterol.
For Cassia Nomame, no effectiveness ratings are on file. The evidence for the proprietary blends themselves isn't established in our data.
How safe is it?
Well-documented data
Most of these ingredients are generally well tolerated in short-term use. Prickly Pear Cactus commonly causes abdominal fullness, indigestion, mild diarrhea, and nausea; rare cases of headache, insomnia, and dizziness have been reported.
Chitosan commonly causes constipation, diarrhea, bloating, stomach discomfort, nausea, and throat dryness; in one case, someone with kidney failure experienced itching. Citrillin HCA (garcinia) commonly causes diarrhea, stomach discomfort, headache, and nausea; rare serious cases include liver injury and liver failure, heart inflammation, and mania.
Alpha-lipoic Acid (R-ALA) commonly causes headache, heartburn, nausea, and vomiting; rare cases of insulin autoimmune syndrome have been reported. Fenugreek extract commonly causes stomach pain, bloating, diarrhea, indigestion, gas, and nausea; severe allergic reactions including anaphylaxis are rare but documented.
None of these ingredients have adequate safety data for pregnancy, and you should avoid them during pregnancy. For breastfeeding: Prickly Pear Cactus, Chitosan, Citrillin HCA, and Alpha-lipoic Acid should be avoided; Fenugreek extract is possibly safe for breastfeeding and is sometimes used to support milk supply, but discuss this with your provider first.
Cassia Nomame has no reliable safety data for breastfeeding.
Meds to double-check
Moderate interaction found
Before taking Cheaters Relief, check with your pharmacist if you take serotonergic drugs (antidepressants, some anxiety medications)—this product carries the most serious risk. Also screen for diabetes medications, blood thinners (warfarin, clopidogrel, or other anticoagulants/antiplatelet drugs), theophylline, phenytoin, sildenafil, metoprolol, acyclovir, thyroid hormone, or any chemotherapy drugs.
If you have liver disease or a history of liver problems, discuss this product with your pharmacist—rare cases of liver injury have been reported.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is a multi-ingredient formula with a wide range of documented interactions, particularly with serotonergic drugs, diabetes medications, blood thinners, and thyroid medications. If you take any prescription drugs—especially antidepressants, blood thinners, diabetes medications, or thyroid hormone—check them against the medication tool before starting.
If you're pregnant or breastfeeding, talk to your pharmacist or doctor first. The ingredients are generally tolerated short-term, but quality evidence for the product's overall effectiveness is limited.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2011.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cheaters Relief, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cheaters Relief by BSN, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Cheaters Relief Proprietary Matrix | 510 mg | -- |
| Fat Relief Blend | 0 NP | -- |
| NeOpuntia Prickly Pear | 0 NP | -- |
| Chitosan | 0 NP | -- |
| Cassia nomame extract | 0 NP | -- |
| Carb Relief Blend | 0 NP | -- |
| Citrillin HCA | 0 NP | -- |
| Phaseo-Lean | 0 NP | -- |
| R-ALA | 0 NP | -- |
| Fenugreek extract | 0 NP | -- |
| Cinnulin-PF | 0 NP | -- |
Other ingredients: Magnesium Stearate, Gelatin, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
DIETARY SUPPLEMENT
Suggested/Recommended/Usage/Directions
Carbs Per Meal 45g-64g 65g-84g 85g + Fats Per Meal 8g-15g 16g-23g 24g + 15 min. Before Meal 2 capsules 3 capsules 4 capsules 15 min. After Meal 2 capsules 3 capsules 4 capsules
Consume a minimum of 120 oz. of water per day alongside a well balanced nutritional program and regular exercise.
RECOMMENDED USE: As a dietary supplement, use the chart below to determine the amount of capsules to take 15-20 minutes prior to, and 15-20 minutes after a meal which corresponds to the carbohydrates and fats listed in the chart. Drink with 8 oz. of water. Any fat-soluble vitamins (A, D, E & K) or essential fatty acids should be taken at least 4 hours before or after ingestion of this product. Do not consume more than 3 servings per day.
Precautions
Keep out of reach of children and pets.
Do no use if you are contemplating pregnancy, pregnant or nursing.
Allergen Warning: DO NOT USE CHEATERS RELIEF(TM) if you are sensitive or allergic to shellfish (this product contains Chitosan which is derived from shellfish).
Manufactured on equipment which processes products containing milk, egg, soybeans, shellfish, fish, tree nuts and peanuts.
Not intended for use by persons under the age of 18.
WARNING: Before consuming CHEATERS RELIEF(TM) seek advice from a health care practitioner if you are unaware of your current health condition or have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, storke; heart, liver, or thyroid disease; anxiety, depression, seizure diorder, psychiatric disease, diabetes, pernicious anemia, difficulty urinating due to prostate enlargement, or if you are taking an MAO inhibitor or any other medication.
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Storage
Store in a cool dry place.
Formula
DESIGNED FOR: Healthy adults seeking to manage unwanted body fat.*
General Statements
CARB & FAT REGULATION* - WEIGHT MANAGEMENT* - LEAN MUSCLE*
CORE SERIES
FOUNDATION
Made in the USA.
PRE & POST-MEAL CARB & FAT REGULATION*
RELIEF
This product contains ingredients of international and domestic origin
General
V.3.120.0409US
Brand IP Statement(s)
CHEATERS RELIEF(TM) supports the following segment of the BSN Supplement Pyramid(TM): Weight Management.
Cinnulin PF(R) is a registered trademark of Integrity Nutraceuticals International.
FINISH FIRST.(R)
MORE FREEDOM TO ENJOY.(TM)*
Stack with ATRO-PHEX(TM), NITRIX(R), LEAN DESSERT PROTEIN(TM), N.O.-XPLODE(TM), AND SYNTHA-6(TM) for maximum physique and performance impact.*
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cheaters Relief by BSN label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cheaters Relief by BSN
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Cheaters Relief Proprietary Matrix
Fat Relief Blend
Carb Relief Blend
- › Citrillin HCA
- › Phaseo-Lean
- › R-ALA
- › Fenugreek extract
- › Cinnulin-PF
Other (inactive) ingredients: Magnesium Stearate, Gelatin, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Cheaters Relief by BSN Drug Interactions
HelloPharmacist Interaction Report
Cheaters Relief by BSN can interact with a number of medications.
The most serious interaction we've documented is with serotonergic drugs (antidepressants, some anti-anxiety medications) via its Citrillin HCA ingredient—combining them theoretically raises the risk of serotonin syndrome, a potentially dangerous condition marked by agitation, confusion, and rapid heart rate. One case report describes a patient who developed serotonin syndrome after taking garcinia extract with escitalopram.
Read the full breakdown — every affected drug type, severity by severity
Moderate interactions are documented with several other drug types. Prickly Pear Cactus can increase the risk of low blood sugar (hypoglycemia) when combined with diabetes medications like metformin and glyburide.
Chitosan may reduce absorption of the antiviral acyclovir and theoretically increase bleeding risk with warfarin. Citrillin HCA also carries moderate risks with blood thinners (anticoagulants/antiplatelet drugs), drugs that damage the liver (hepatotoxic drugs), and diabetes medications.
Alpha-lipoic Acid (R-ALA) may increase bleeding risk with anticoagulants or antiplatelet drugs, alter how certain chemotherapy drugs work, and theoretically lower thyroid hormone effectiveness; it carries a minor risk with diabetes medications. Fenugreek extract has multiple documented moderate interactions: with blood thinners, diabetes medications, theophylline, warfarin, clopidogrel, metoprolol, phenytoin, and sildenafil.
We could not check interaction data for three ingredients: the Cheaters Relief Proprietary Matrix, Phaseo-Lean, and Cinnulin-PF. Cassia Nomame was checked and shows no interactions documented in our data.
Although this list is extensive, it reflects the medications we have data for—not necessarily every medication that might interact. Use the medication checker on this page to search your exact drugs before starting Cheaters Relief.
Altogether, these interactions span 917 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Cheaters Relief?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Cheaters Relief interact with 916 drugs. Click any drug to see the details.
5 of the 9 ingredients in Cheaters Relief interact with drugs. Each result below shows which ingredient is responsible. Citrillin HCA Fenugreek extract R-ALA NeOpuntia Prickly Pear Chitosan
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Cheaters Relief — through 3 ingredients. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Abciximab interactionCitrillin HcaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Citrillin Hca + Abciximab interactionFenugreek ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Extract + Abciximab interactionAbiraterone
How Abiraterone interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Cheaters Relief — through 3 ingredients. Tap an ingredient for the detail:
Citrillin HcaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Citrillin Hca + Abrocitinib interactionFenugreek ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Extract + Abrocitinib interactionR-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Cheaters Relief — through 4 ingredients. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acarbose interactionFenugreek ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Extract + Acarbose interactionNeopuntia Prickly PearAntidiabetes Drugs Moderate
Interaction Summary
Combining prickly pear cactus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Neopuntia Prickly Pear + Acarbose interactionR-alaAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking alpha-lipoic acid with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full R-ala + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Cheaters Relief — through 2 ingredients. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acebutolol interactionFenugreek ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Cheaters Relief — through 3 ingredients. Tap an ingredient for the detail:
Fenugreek ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Extract + Acenocoumarol interactionR-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Acenocoumarol interactionCitrillin HcaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Citrillin Hca + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Cheaters Relief — through 3 ingredients. Tap an ingredient for the detail:
Fenugreek ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Extract + Acetaminophen, Aspirin interactionR-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Acetaminophen, Aspirin interactionCitrillin HcaHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Cheaters Relief — through 3 ingredients. Tap an ingredient for the detail:
Citrillin HcaAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Citrillin Hca + Acetaminophen, Aspirin, Caffeine interactionR-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Acetaminophen, Aspirin, Caffeine interactionFenugreek ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Citrillin Hca + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Citrillin Hca + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Citrillin Hca + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Citrillin Hca + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Cheaters Relief — through 1 ingredient. Tap an ingredient for the detail:
Citrillin HcaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Citrillin Hca + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Cheaters Relief with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Citrillin HCA
Anticoagulant/Antiplatelet Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
HCA inhibits platelet aggregation in vitro. The inhibitory effect seems to be greater in platelets extracted from diabetic subjects than non-diabetic subjects.
Antidiabetes Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
HCA reduces fasting and postprandial blood glucose levels in animal models, theoretically by delaying glucose absorption. This effect has not been reported in humans.
Hepatotoxic Drugs
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
There have been reports of acute hepatitis with elevated liver enzymes associated with garcinia, when taken alone or in combination with other ingredients. Case reports collected from the Drug Induced Liver Injury Network suggest this risk may be greater in people who carry the HLA B*35:01 allele.
Serotonergic Drugs
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
In one report, a patient experienced serotonin syndrome after taking garcinia extract (60% hydroxycitric acid) 1000 mg daily in combination with escitalopram 20 mg, which had been taken for a year. The patient was switched to sertraline 50 mg daily and again experienced serotonin syndrome.
Fenugreek extract
Anticoagulant/Antiplatelet Drugs
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .
Antidiabetes Drugs
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.
Clopidogrel (Plavix)
Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.
Metoprolol (Toprol)
Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.
Phenytoin (Dilantin)
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.
Sildenafil (Viagra)
Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.
Theophylline
Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.
Warfarin (Coumadin)
Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.
Antihypertensive Drugs
Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.
R-ALA
Alkylating Agents
Theoretically, the antioxidant effects of alpha-lipoic acid might alter the effectiveness of alkylating agents.
The use of antioxidants like alpha-lipoic acid during chemotherapy is controversial. There are concerns that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as alpha-lipoic acid have on chemotherapy. Advise patients to consult their oncologist before using alpha-lipoic acid.
Anticoagulant/Antiplatelet Drugs
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro, alpha-lipoic acid inhibits platelet aggregation.
Antitumor Antibiotics
Theoretically, the antioxidant effects of alpha-lipoic acid might alter the effectiveness of antitumor antibiotics.
The use of antioxidants like alpha-lipoic acid during chemotherapy is controversial. There are concerns that antioxidants could reduce the activity of antitumor antibiotic drugs, which work by generating free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as alpha-lipoic acid have on chemotherapy involving antitumor antibiotics. Advise patients to consult their oncologist before using alpha-lipoic acid.
Thyroid Hormone
Theoretically, alpha-lipoic acid might decrease the effects of thyroid hormone drugs.
Animal research suggests that co-administration of thyroxine with alpha-lipoic acid reduces conversion into the active T3 form.
Antidiabetes Drugs
Theoretically, taking alpha-lipoic acid with antidiabetes drugs might increase the risk of hypoglycemia.
Although some small clinical studies have suggested that alpha-lipoic acid can lower blood glucose levels, larger clinical studies in patients with diabetes have shown no clinically meaningful effect. Additionally, co-administration of single doses of alpha-lipoic acid and glyburide or acarbose did not cause detectable drug interactions in healthy volunteers.
NeOpuntia Prickly Pear
Antidiabetes Drugs
Combining prickly pear cactus with antidiabetes drugs might increase the risk of hypoglycemia.
Case reports show that combining prickly pear cactus with antidiabetes drugs such as chlorpropamide, glyburide, glipizide, and metformin can increase the risk of hypoglycemia in patients with type 2 diabetes. Advise patients to monitor glucose levels closely. Dose adjustments may be necessary.
Chitosan
Acyclovir (Zovirax)
Chitosan can reduce the absorption of acyclovir, potentially increasing the risk for treatment failure.
Clinical research in humans shows that taking chitosan along with acyclovir 200 mg reduces acyclovir absorption. Concomitant administration of chitosan 400 mg or 1000 mg reduced the acyclovir area under the curve (AUC) and peak plasma concentration by about 30% and 40%, respectively, compared with control. Concomitant administration with chitosan 1000 mg also increased time to peak concentration from 1 hour to 2 hours. In vitro research suggests that the mechanism for reduced absorption is due to acyclovir entrapment in chitosan-mucus complexes, which reduces intestinal absorption.
Warfarin (Coumadin)
Theoretically, chitosan might increase the risk of bleeding when taken with warfarin.
In a case report, a patient taking warfarin had a significantly increased international normalized ratio (INR) after starting chitosan 1200 mg daily. The INR normalized after chitosan was discontinued and vitamin K was administered. The patient once again started taking chitosan and again had a significant increase in INR. The INR stabilized again once chitosan was discontinued. Researchers theorize that this interaction might occur because chitosan decreases absorption of fat-soluble vitamins, including vitamin K, which could increase the anticoagulant effect of warfarin.
Brand information
Manufacturer and brand details for Cheaters Relief, from the product label.
Cheaters Relief by BSN: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cheaters Relief’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Prickly Pear Cactus
Interacts with 86 drugsPrickly pear cactus is a desert plant whose pads and fruit are eaten as food and taken as a supplement, mainly for blood sugar, cholesterol, and hangover symptoms. Some small studies suggest...
Read the full Prickly Pear Cactus monograph → Herb & supplement monographChitosan
Interacts with 3 drugsChitosan is a fiber-like substance made from the shells of shrimp, crabs, and other shellfish, often marketed for weight loss and cholesterol. The evidence for these benefits is weak, and an...
Read the full Chitosan monograph → Herb & supplement monographCassia Nomame
Cassia nomame is a legume plant traditionally used in parts of Asia and now marketed mainly in weight-loss supplements for its supposed ability to block fat absorption. Human evidence is ver...
Read the full Cassia Nomame monograph → Herb & supplement monographGarcinia
Interacts with 704 drugsGarcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific evidence is weak and mixed, with most studies...
Read the full Garcinia monograph → Herb & supplement monographAlpha-lipoic Acid
Interacts with 263 drugsAlpha-lipoic acid (ALA) is an antioxidant made naturally by the body and found in small amounts in foods. It is most studied for diabetic nerve pain, where some evidence suggests it may help...
Read the full Alpha-lipoic Acid monograph → Herb & supplement monographFenugreek
Interacts with 389 drugsFenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. Some early research is encouraging for blo...
Read the full Fenugreek monograph →Sources & How We Checked
Cheaters Relief's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 151 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Prickly Pear Cactus 9 references
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- Rayburn K, Martinez R, Escobedo M, et al. Glycemic effects of various species of nopal (Opuntia sp.) in type 2 diabetes mellitus. Texas J Rural Health 1998;26:68-76.
- Bush TM, Rayburn KS, Holloway SW, et al. Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey. Altern Ther Health Med 2007;13:30-5.
- Sobieraj DM, Freyer CW. Probable hypoglycemic adverse drug reaction associated with prickly pear cactus, glipizide, and metformin in a patient with type 2 diabetes mellitus. Ann Pharmacother 2010;44:1334-7. PubMed
- Kleiner, O., Cohen, Z., and Mares, A. J. Low colonic obstruction due to Opuntia ficus indica seeds: the aftermath of enjoying delicious cactus fruits. Acta Paediatr. 2002;91(5):606-607.
- Steinberg, J. M. and Eitan, A. Prickly pear fruit bezoar presenting as rectal perforation in an elderly patient. Int J Colorectal Dis. 2003;18(4):365-367. PubMed
- Meckes-Lozyoa, M. and Roman-Ramos, R. Opuntia streptacantha: a coadjutor in the treatment of diabetes mellitus. Am J Chin Med 1986;14(3-4):116-118.
- Onakpoya IJ, O'Sullivan J, Heneghan CJ. The effect of cactus pear (Opuntia ficus-indica) on body weight and cardiovascular risk factors: a systematic review and meta-analysis of randomized clinical trials. Nutrition. 2015;31(5):640-6. PubMed
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Chitosan 17 references
- Jing SB, Li L, Ji D, et al. Effect of chitosan on renal function in patients with chronic renal failure. J Pharm Pharmacol 1997;49:721-3. PubMed
- Pittler MH, Abbot NC, Harkness EF, Ernst E. Randomized, double-blind trial of chitosan for body weight reduction. Eur J Clin Nutr 1999;53:379-81. PubMed
- Ho SC, Tai ES, Eng PH, et al. In the absence of dietary surveillance, chitosan does not reduce plasma lipids or obesity in hypercholesterolaemic obese Asian subjects. Singapore Med J 2001;42:6-10.
- Bokura H, Kobayashi S. Chitosan decreases total cholesterol in women: a randomized, double-blind, placebo-controlled trial. Eur J Clin Nutr 2003;57:721-5. PubMed
- Mhurchu CN, Poppitt SD, McGill AT, et al. The effect of the dietary supplement, Chitosan, on body weight: a randomised controlled trial in 250 overweight and obese adults. Int J Obes Relat Metab Disord 2004;28:1149-56. PubMed
- Huang SS, Sung SH, Chiang CE. Chitosan potentiation of warfarin effect. Ann Pharmacother 2007;41:1912-4. PubMed
- Tsai, G. J. and Su, W. H. Antibacterial activity of shrimp chitosan against Escherichia coli. J Food Prot. 1999;62(3):239-243. PubMed
- Wuolijoki, E., Hirvela, T., and Ylitalo, P. Decrease in serum LDL cholesterol with microcrystalline chitosan. Methods Find.Exp Clin Pharmacol. 1999;21(5):357-361. PubMed
- Nelson, J. L., Alexander, J. W., Gianotti, L., Chalk, C. L., and Pyles, T. Influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutrition 1994;10(1):32-36.
- Schiller RN, Barrager E, Schauss EA, and et al. A randomized, double-blind, placebo-controlled study examining the effects of a rapidly soluble chitosan dietary supplement on weight loss and body composition in overweight and mildly obese individuals. J
- Koide, S. S. Chitin-chitosan: properties, benefits and risks. Nutrition Research 1998;8(6):1091-1101. DOI
- Maezaki Y, Tsuji K, Nakawa, and et al. Hypocholesterolaemic effect of chitosan in adult males. Biosc Biochem Biotech 1993;57:1439-1444.
- Kubbinga M, Nguyen MA, Staubach P, et al. The influence of chitosan on the oral bioavailability of acyclovir-a comparative bioavailability study in humans. Pharm Res 2015;32(7):2241-9. PubMed
- Jull AB, Ni Mhurchu C, Bennett DA, et al. Chitosan for overweight or obesity. Cochrane Database Syst Rev 2008;(3):CD003892. PubMed
- Schmidl D, Werkmeister R, Kaya S, et al. A Controlled, Randomized Double-Blind Study to Evaluate the Safety and Efficacy of Chitosan-N-Acetylcysteine for the Treatment of Dry Eye Syndrome. J Ocul Pharmacol Ther. 2017;33(5):375-382.
- Moraru C, Mincea MM, Frandes M, Timar B, Ostafe V. A meta-analysis on randomised controlled clinical trials evaluating the effect of the dietary supplement chitosan on weight loss, lipid parameters and blood pressure. Medicina (Kaunas). 2018;54(6):109. PubMed
- García MA, Hensler G, Al-Gousous J, Pielenhofer J, Wagner M, Lennernäs H, Langguth P. Novel food drug interaction mechanism involving acyclovir, chitosan and endogenous mucus. Drug Metab Pharmacokinet. 2023;49:100491. PubMed
Cassia Nomame 3 references
Garcinia 44 references
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- Soni MG, Burdock GA, Preuss HG, et al. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol 2004;42:1513-29. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Willis SL, Moawad FJ, Hartzell JD, et al. Hypertensive retinopathy associated with use of the ephedra-free weight-loss herbal supplement Hydroxycut. MedGenMed 2006;8:82.
- Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180.
- Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. Am J Med Sci 2004;327:356-357. PubMed
- Lopez AM, Kornegay J, Hendrickson RG. Serotonin Toxicity Associated with Garcinia cambogia Over-the-counter Supplement. J Med Toxicol. 2014 Apr 4. [Epub ahead of print]. PubMed
- Michno A, Skibowska A, Raszeja-Specht A, Cwikowska J, Szutowicz A. The role of adenosine triphosphate citrate lyase in the metabolism of acetyl coenzyme a and function of blood platelets in diabetes mellitus. Metabolism 2004;53(1):66-72. PubMed
- Asghar M, Monjok E, Kouamou G, et al. Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in developing obese Zucker rats. Mol Cell Biochem 2007;304(1-2):93-99. PubMed
- Wielinga PY, Wachters-Hagedoorn RE, Bouter B, et al. Hydroxycitric acid delays intestinal glucose absorption in rats. Am J Physiol Gastrointest Liver Physiol 2005;288(6):G1144-G1149. PubMed
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- Bunchorntavakul, C. and Reddy, K. R. Review article: herbal and dietary supplement hepatotoxicity. Aliment.Pharmacol.Ther 2013;37(1):3-17. PubMed
- Vasques CA, Schneider R, Klein-Júnior LC, et al. Hypolipemic effect of Garcinia Cambogia in obese women. Phytother Res 2014;28(6):887-91.
- Marquez F, Babio N, Bullo M, Salas-Salvado J. Evaluation of the safety and efficacy of hydroxycitric acid or Garcinia cambogia extracts in humans. Crit Rev Food Sci Nutr 2012;52:585-94.
- Allen SF, Godley RW, Evron JM, et al. Acute necrotizing eosinophilic myocarditis in a patient taking Garcinia cambogia extract successfully treated with high-dose corticosteroids. Can J Cardiol 2014;30(12):1732 e13-1732 e15. PubMed
- Dara L, Hewett J, Lim JK. Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements. World J Gastroenterol. 2008 Dec 7;14(45):6999-7004. PubMed
- Sharma T, Wong L, Tsai N, Wong RD. Hydroxycut(®) (herbal weight loss supplement) induced hepatotoxicity: a case report and review of literature. Hawaii Med J. 2010 Aug;69(8):188-90.
- Rashid NN, Grant J. Hydroxycut hepatotoxicity. Med J Aust. 2010 Feb 1;192(3):173-4. PubMed
- Actis GC, Bugianesi E, Ottobrelli A, Rizzetto M. Fatal liver failure following food supplements during chronic treatment with montelukast. Dig Liver Dis. 2007 Oct;39(10):953-5. PubMed
- Corey R, Werner KT, Singer A, Moss A, Smith M, Noelting J, Rakela J. Acute liver failure associated with Garcinia cambogia use. Ann Hepatol. 2016 Jan-Feb;15(1):123-6. PubMed
- Melendez-Rosado J, Snipelisky D, Matcha G, Stancampiano F. Acute hepatitis induced by pure Garcinia cambogia. J Clin Gastroenterol. 2015 May-Jun;49(5):449-50. PubMed
- García-Cortés M, Robles-Díaz M, Ortega-Alonso A, Medina-Caliz I, Andrade RJ. Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics. Int J Mol Sci. 2016 Apr 9;17(4):537. PubMed
- Dehoney S, Wellein M. Rhabdomyolysis associated with the nutritional supplement Hydroxycut. Am J Health Syst Pharm. 2009;66(2):142-8. PubMed
- Fong TL, Klontz KC, Canas-Coto A, et al. Hepatotoxicity due to hydroxycut: a case series. Am J Gastroenterol. 2010;105(7):1561-6. PubMed
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- Lobb A. Hepatoxicity associated with weight-loss supplements: a case for better post-marketing surveillance. World J Gastroenterol. 2009;15(14):1786-7. PubMed
- Lunsford KE, Bodzin AS, Reino DC, Wang HL, Busuttil RW. Dangerous dietary supplements: Garcinia cambogia -associated hepatic failure requiring transplantation. World J Gastroenterol. 2016;22(45):10071-10076.
- Narasimha A, Shetty PH, Nanjundaswamy MH, Viswanath B, Bada Math S. Hydroxycut - Dietary supplements for weight loss: Can they induce mania? Aust N Z J Psychiatry. 2013;47(12):1205-6. PubMed
- Shim M, Saab S. Severe hepatotoxicity due to Hydroxycut: a case report. Dig Dis Sci. 2009;54(2):406-8. PubMed
- Stohs SJ, Preuss HG, Ohia SE, et al. No evidence demonstrating hepatotoxicity associated with hydroxycitric acid. World J Gastroenterol. 2009;15(32):4087-9. PubMed
- Gavril A, Ribnikar M, Smid L, Luzar B, Stabuc B. Fat burner-induced acute liver injury: case series of four patients. Nutrition. 2018;47:110-114. doi: 10.1016/j.nut.2017.10.002. PubMed
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Alpha-lipoic Acid 48 references
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- Jacob S, Henriksen EJ, Schiemann AL, et al. Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45:872-4.
- Jacob S, Ruus P, Hermann R, et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled, pilot trial. Free Rad Biol Med 1999;27:309-14.
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- Gu X. M., Zhang S. S., Wu J. C., Tang Z. Y., Lu Z. Q., Li H., Liu C., Chen L., Ning, G. [Efficacy and safety of high-dose a-lipoic acid in the treatment of diabetic polyneuropathy]. Zhonghua Yi Xue Za Zhi 2010;90(35):2473-2476.
- Porasuphatana S., Suddee S., Nartnampong A., Konsil J., Harnwong B., Santaweesuk A. Glycemic and oxidative status of patients with type 2 diabetes mellitus following oral administration of alpha-lipoic acid: a randomized double-blinded placebo-controlled
- Ansar H., Mazloom Z., Kazemi F., Hejazi N. Effect of alpha-lipoic acid on blood glucose, insulin resistance and glutathione peroxidase of type 2 diabetic patients. Saudi Med J 2011;32(6):584-588. DOI
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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