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Dietary supplement

Children's Acidophilus Ingredients & Drug Interactions

by Vitabase

Children's Acidophilus label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Children's Acidophilus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Children's Acidophilus is a dietary supplement by Vitabase with 3 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacilli acidophilus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Children's Acidophilus by Vitabase

Ask about any prescription or over-the-counter medication and we check it for interactions with Children's Acidophilus by Vitabase — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Children's Acidophilus by Vitabase

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary probiotic blend” is a proprietary blend — the label gives one combined amount (12 mg) without saying how much of each component you get.

This product has 3 active ingredients: two named Lactobacillus strains (salivarius and acidophilus) and Bifidobacterium animalis lactis, all live bacteria that are meant to support digestive and immune health. These are probiotics — beneficial microorganisms — suspended in a tablet form.

The other ingredients listed are inactive: fillers, flavors, and binders that help hold the tablet together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Digestive health and balance for children.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Colic, Constipation, Clostridioides difficile infection, Irritable bowel syndrome (IBS) — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Lactose intolerance, Rotaviral diarrhea, Travelers' diarrhea.

The evidence for Lactobacillus acidophilus shows it's possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis. For atopic disease (allergic conditions) the evidence suggests it may not be effective, and there isn't enough reliable evidence yet to say how it performs for acute respiratory distress syndrome.

The effectiveness data we hold applies only to L. acidophilus; we don't have comparable evidence ratings for the other two bacteria in this product.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy children. That said, there is some caution worth noting: since it contains live, active microorganisms, there's a theoretical concern that in rare cases it could cause infection in certain patients — cases of bacteremia (bacteria in the bloodstream), sepsis, and other serious infections have been isolated, though these are thought to occur mainly when bacteria move from other parts of the body where they naturally live.

Orally, taking this product with other probiotics may occasionally cause mild gastrointestinal side effects like belly discomfort, gas, bloating, diarrhea, or burping, but these are uncommon. One trial reported a few cases of rash and itching, though it's unclear whether L. acidophilus or another factor was responsible.

For pregnancy and lactation, Lactobacillus acidophilus is rated possibly safe during pregnancy. There is no lactation data on file for this ingredient in our records, so talk with your pharmacist or doctor about breastfeeding use.

The safety data for the other two bacteria in this product is limited, so ask your healthcare provider before use, especially if your child has a weakened immune system or is very ill.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotic drugs are the main concern: they can kill the live bacteria in this product and reduce its effectiveness. Since these bacteria have been linked in rare cases to serious infections in vulnerable patients, ask your pharmacist to review your child's full health picture before starting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a multi-strain probiotic aimed at children's digestive health. If your child is on antibiotics, separate the timing — don't give them together — and check the exact antibiotic with your pharmacist first.

For any child with a serious illness or weakened immunity, talk with your doctor before starting it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Children's Acidophilus, straight from the product label.

Brand Vitabase
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Mar 23, 2012
DSLD ID 7019
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Children's Acidophilus by Vitabase, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
IngredientAmount% DV
Lactobacillus salivarius0 NP--
Bifidobacterium animalis lactis0 NP--
Proprietary probiotic blend12 mg--
Lactobacilli acidophilus0 NP--

Other ingredients: Sorbitol, Xylitol, natural Grape flavor, Microcrystalline Cellulose, Vegetable Stearin, Maltodextrin, Citric Acid, Silica, Magnesium Stearate, luo han guo fruit extract, Carmine color

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, children five (5) years and older chew one (1) tablet daily during a meal, or as directed by a health care professional.

Storage

Store in a cool, dry place and away from direct light.

No refrigeration required.

General Statements

QUALITY AND POTENCY GUARANTEED.

Each Bio-Enhanced, Acid Resistant Strain (BEARS) has been specifically designed to survive stomach acid secretions during digestion. BEARS eliminates the need for enteric coating by preventing the destruction of viable cells that occurs when weaker strains are exposed to an acid environment.

This proprietary blend is produced exclusively by Danisco, a world leader in probiotics. Danisco's probiotic strains are stabilized using a patented poly matrix system (patent # 6,653,062) that provides shelf stability at normal room temperature.

Chewable Grape Flavor Protected Against Stomach Acid

Formulation

Contains No salt, yeast, wheat, soy, gluten, preservatives, artificial colors or flavors.

FDA Statement of Identity

DIETARY SUPPLEMENT

Formula

Contains milk.

Seals/Symbols

Vb

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Children's Acidophilus by Vitabase label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Children's Acidophilus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Children's Acidophilus by Vitabase

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary probiotic blend

12 mg per serving

Other (inactive) ingredients: Sorbitol, Xylitol, Natural Grape flavor, Microcrystalline Cellulose, Vegetable Stearin, Maltodextrin, Citric Acid, Silica, Magnesium Stearate, Luo han guo fruit extract, Carmine color. These complete the product’s ingredient list but are not active constituents.

Interaction report

Children's Acidophilus by Vitabase Drug Interactions

Want to check YOUR meds against Children's Acidophilus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacilli acidophilus 182

Individual Drug Interactions

The ingredients in Children's Acidophilus interact with 182 drugs. Click any drug to see the details.

1 of the 3 ingredients in Children's Acidophilus interact with drugs. Each result below shows which ingredient is responsible. Lactobacilli acidophilus

Each ingredient & the kinds of drugs it affects

For each ingredient in Children's Acidophilus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacilli acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacilli acidophilus full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Children's Acidophilus, from the product label.

Vitabase

See all Vitabase products
Name
Vitabase.com
City
Monroe
State
GA
ZipCode
30656
Pharmacist Counseling Corner

Children's Acidophilus by Vitabase: Common Questions

Does Children's Acidophilus by Vitabase interact with any medications?
Yes. Based on its ingredients, Children's Acidophilus has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Children's Acidophilus contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can my child take this at the same time as an antibiotic?
No — antibiotics can kill off the live bacteria in this probiotic, making it less effective. Ask your pharmacist to help you space them apart, usually a few hours before or after the antibiotic dose.
What does this product do?
It contains live beneficial bacteria (probiotics) that may help with irritable bowel syndrome, antibiotic-associated diarrhea, certain bacterial infections, and vaginal health. The evidence shows it's possibly effective for these uses, though results vary.
Is it safe for my child?
It's generally well tolerated in healthy kids. But since it has live organisms, check with your doctor first if your child has a weakened immune system or serious illness. Also ask about pregnancy use if relevant — it's rated possibly safe, but data for breastfeeding are not on file.
What side effects might happen?
Mild belly discomfort, gas, bloating, diarrhea, or burping are uncommon but possible. In rare cases, rash or itching has been reported, though it's not clear if the probiotic was responsible.
What are the inactive ingredients for?
They're fillers and binders that help hold the tablet together and make it taste better — things like sorbitol, xylitol, grape flavor, and cellulose. They're not active medicine.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Children's Acidophilus is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Children's Acidophilus label
Go deeper

The Full Monographs Behind Children's Acidophilus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Children's Acidophilus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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