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Dietary supplement

Choline L-Bitartrate & Inositol 1000 mg Ingredients & Drug Interactions

by NusaPure

Choline L-Bitartrate & Inositol 1000 mg label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Choline L-Bitartrate & Inositol 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Choline L-Bitartrate & Inositol 1000 mg is a dietary supplement by NusaPure with 2 active ingredients. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 102 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol, Choline L-Bitartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Choline L-Bitartrate & Inositol 1000 mg by NusaPure

Ask about any prescription or over-the-counter medication and we check it for interactions with Choline L-Bitartrate & Inositol 1000 mg by NusaPure — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Choline L-Bitartrate & Inositol 1000 mg by NusaPure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Choline L-Bitartrate” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.

This product contains 2 active ingredients: inositol and choline, supplied as choline L-bitartrate. The capsules also contain inactive ingredients (cellulose, magnesium stearate, rice flour, and silica) which are fillers and binders that help deliver the actives.

Inositol is a naturally occurring compound your body makes, involved in cell signaling and blood sugar regulation. Choline is an essential nutrient important for nerve and brain function, as well as cell structure.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Polycystic ovary syndrome (PCOS) — rated "Possibly Effective" (Inositol) (Natural Medicines).
  • On file: Preterm labor — rated "Possibly Effective" (Inositol) (Natural Medicines).
  • On file: Metabolic syndrome — rated "Possibly Effective" (Inositol) (Natural Medicines).

Inositol is possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome, and possibly effective for preventing preterm labor. The evidence rates it as possibly ineffective for anxiety, diabetic nerve pain (diabetic neuropathy), and depression.

Choline's evidence is more limited here. We hold insufficient reliable evidence to rate it for athletic performance, bronchitis, age-related cognitive decline, liver fat (TPN-associated hepatic steatosis), hay fever, or Alzheimer disease.

The evidence, ingredient by ingredient Inositol Choline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated at normal doses, though some people experience mild digestive side effects like diarrhea, gas, or nausea. Safety in pregnancy hasn't been fully established, so use only under medical supervision if you're pregnant or planning to become pregnant.

Choline is likely safe during pregnancy and breastfeeding when used at the right dose, though your doctor should guide supplementation since choline needs are higher during breastfeeding. At high doses (9 grams daily or more), choline can cause fishy body odor, diarrhea, nausea, and vomiting.

The safe upper limit is 3.5 grams daily.

Side effects, ingredient by ingredient Inositol Choline

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Inositol, Choline.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 102 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your exact medications if you take antidiabetes drugs (metformin, insulin, sulfonylureas, and others)—inositol may increase low blood sugar risk and needs monitoring. Also flag any use of atropine or similar anticholinergic medications, though that interaction is minor.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Consider this supplement if you have PCOS, metabolic syndrome, or want to support brain and nerve function—but inositol may lower your blood sugar, so diabetes medication users need to check with us first. Choline is generally well tolerated at the dose here.

If you're pregnant, breastfeeding, or take any prescription medications, talk to your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Choline L-Bitartrate & Inositol 1000 mg, straight from the product label.

Brand NusaPure
Barcode (UPC) X001WSB07H
Net contents 200 Veg Cap(s)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 246353
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Choline L-Bitartrate & Inositol 1000 mg by NusaPure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veggie Capsule(s)
Maximum serving Sizes:
2 Veggie Capsule(s)
Servings per container
100
UPC/BARCODE
X001WSB07H
IngredientAmount% DV
Inositol500 mg--
Choline195 mg--
Choline L-Bitartrate500 mg35%

Other ingredients: Cellulose, Magnesium Stearate, Rice Flour, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) capsules daily preferably with a meal.

Precautions

Warning: Pregnant or lactating women should consult a doctor before using any product. Consult your doctor before use if you had, or have had, any health condition or if you are taking any medications or remedies including OTC medications or are planning any medical procedure.

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Storage

Store in cool dry place. Avoid excessive heat or moisture.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Premium Quality Assembled in USA GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility

Manufactured in a cGMP Inspected Facility

Formulation

GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility

1000 mg per serving Assembled in USA Tested Supports healthy nerve transmission Supports fatty acid metabolism Supports healthy brain function Supports healthy cell membranes Max Strength

Allergen Information: Contains no artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

Natural color variation may occur in this product.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Choline L-Bitartrate & Inositol 1000 mg by NusaPure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Choline L-Bitartrate & Inositol 1000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Choline L-Bitartrate & Inositol 1000 mg by NusaPure

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Inositol

Interacts with
86 drugs
500 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions

Choline L-Bitartrate

Interacts with
16 drugs
500 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline L-Bitartrate monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Rice Flour, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Choline L-Bitartrate & Inositol 1000 mg by NusaPure Drug Interactions

Want to check YOUR meds against Choline L-Bitartrate & Inositol 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
102Drugs
86 Moderate 16 Minor

Ingredients driving the most interactions

Inositol 86
Choline L-Bitartrate 16

Individual Drug Interactions

The ingredients in Choline L-Bitartrate & Inositol 1000 mg interact with 102 drugs. Click any drug to see the details.

2 of the 2 ingredients in Choline L-Bitartrate & Inositol 1000 mg interact with drugs. Each result below shows which ingredient is responsible. Inositol Choline L-Bitartrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Choline L-Bitartrate & Inositol 1000 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol full monograph & interactions

Choline L-Bitartrate1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline L-Bitartrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Choline L-Bitartrate & Inositol 1000 mg, from the product label.

NusaPure

See all NusaPure products
Name
Gmax Central LLC
Street Address
4700 Millenia Boulevard, Suite 175 PMB 92909
City
Orlando
State
FL
ZipCode
32839
Pharmacist Counseling Corner

Choline L-Bitartrate & Inositol 1000 mg by NusaPure: Common Questions

Does Choline L-Bitartrate & Inositol 1000 mg by NusaPure interact with any medications?
Yes. Based on its ingredients, Choline L-Bitartrate & Inositol 1000 mg has a known interaction with 102 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Choline L-Bitartrate & Inositol 1000 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this lower my blood sugar if I take diabetes medication?
Inositol does lower blood sugar, so pairing it with diabetes drugs creates a moderate risk of low blood sugar (hypoglycemia). Don't start this without checking your exact medications with a pharmacist first—your doctor may need to adjust your diabetes medication dose.
Is it safe to take while pregnant?
Inositol hasn't been fully studied in pregnancy, so use only under medical supervision if you're pregnant or trying to conceive. Choline is likely safe during pregnancy, but your doctor should guide the dose. Talk to your OB or pharmacist about what's right for you.
Can I take this while breastfeeding?
Choline is likely safe while breastfeeding and may be especially important then, but only use as directed by your healthcare provider. There's not enough data on inositol during breastfeeding, so check with your doctor before adding this supplement.
What are the most common side effects?
Inositol may cause mild digestive upset—diarrhea, gas, or nausea. Choline can cause a fishy body odor. These are uncommon at normal doses, but high doses of choline (9+ grams daily) bring more severe digestive symptoms; this product is unlikely to reach that level on its own.
Does this actually work for PCOS or metabolic syndrome?
Inositol is possibly effective for both PCOS and metabolic syndrome based on clinical research. Results vary by person, and it's not a replacement for diet, exercise, or prescribed treatment—talk to your doctor about whether it fits your plan.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Choline L-Bitartrate & Inositol 1000 mg label
Go deeper

The Full Monographs Behind Choline L-Bitartrate & Inositol 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph → Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph →
Sources

Sources & How We Checked

Choline L-Bitartrate & Inositol 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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